Wyszukiwarka
Filtry
wszystkich: 27
wybranych: 22
-
Katalog
Filtry wybranego katalogu
Wyniki wyszukiwania dla: casp
-
Melatonin maintains mitochondrial membrane potential and attenuates activation of initiator (casp-9) and effector caspases (casp-3/casp-7) and PARP in UVR-exposed HaCaT keratinocytes
Publikacja -
Modeling SARS‐CoV‐2 proteins in the CASP‐commons experiment
PublikacjaCritical Assessment of Structure Prediction (CASP) is an organization aimed at advancing the state of the art in computing protein structure from sequence. In the spring of 2020, CASP launched a community project to compute the structures of the most structurally challenging proteins coded for in the SARS-CoV-2 genome. Forty-seven research groups submitted over 3000 three-dimensional models and 700 sets of accuracy estimates on...
-
An analysis and evaluation of the WeFold collaborative for protein structure prediction and its pipelines in CASP11 and CASP12
Publikacja -
Nonstationary Pharmacokinetics of Caspofungin in ICU Patients
Publikacja -
Caspase-11 promotes allergic airway inflammation
Publikacja -
Prediction of protein assemblies, the next frontier: The CASP14‐CAPRI experiment
PublikacjaWe present the results for CAPRI Round 50, the 4th joint CASP-CAPRI protein assembly prediction challenge. The Round comprised a total of 12 targets, including 6 dimers, 3 trimers, and 3 higher-order oligomers. Four of these were easy targets, for which good structural templates were available either for the full assembly, or for the main interfaces (of the higher-order oligomers). Eight were difficult targets for which only distantly...
-
Impact of AlphaFold on structure prediction of protein complexes: The CASP15‐CAPRI experiment
PublikacjaWe present the results for CAPRI Round 54, the 5th joint CASP-CAPRI protein assembly prediction challenge. The Round offered 37 targets, including 14 homodimers, 3 homo-trimers, 13 heterodimers including 3 antibody–antigen complexes, and 7 large assemblies. On average 70 CASP and CAPRI predictor groups, including more than 20 automatics servers, submitted models for each target. A total of 21 941 models submitted by these groups...
-
ISO/IEC 27001-Based Estimation of Cybersecurity Costs with Caspea
PublikacjaIn the contemporary, knowledge-based economy, enterprises are forced to bear the costs related to cybersecurity. While breaches negatively affect companies' budgets, accurate decisions on security investments result in visible savings. At the same time, cybersecurity cost assessment methods that support these decisions are lacking. Caspea addresses the gap by enabling the estimation of costs related to personnel activities involved...
-
Lessons from application of the UNRES force field to predictions of structures of CASP10 targets
Publikacja -
Estimating the Cost of Cybersecurity Activities with CAsPeA: A Case Study and Comparative Analysis
PublikacjaContemporary approaches to the estimation of cybersecurity costs in organisations tend to focus on the cost of incidents or technological investments. However, there are other, less transparent costs related to cybersecurity management that need to be properly recognised in order to get a complete picture. These costs are associated with everyday activities and the time spent by employees on cybersecurity-related actions. Such...
-
Assessment of chemical‐crosslink‐assisted protein structure modeling in CASP13
Publikacja -
Modeling protein structures with the coarse-grained UNRES force field in the CASP14 experiment
PublikacjaThe UNited RESidue (UNRES) force field was tested in the 14th Community Wide Experiment on the Critical Assessment of Techniques for Protein Structure Prediction (CASP14), in which larger oligomeric and multimeric targets were present compared to previous editions. Three prediction modes were tested (i) ab initio (the UNRES group), (ii) contact-assisted (the UNRES- contact group), and (iii) template-assisted (the UNRES-template...
-
Performance of protein-structure predictions with the physics-based UNRES force field in CASP11
Publikacja -
Blind prediction of homo‐ and hetero‐protein complexes: The CASP13‐CAPRI experiment
Publikacja -
Improved Consensus-Fragment Selection in Template-Assisted Prediction of Protein Structures with the UNRES Force Field in CASP13
Publikacja -
Evaluation of the scale-consistent UNRES force field in template-free prediction of protein structures in the CASP13 experiment
Publikacja -
Use of the UNRES force field in template-assisted prediction of protein structures and the refinement of server models: Test with CASP12 targets
Publikacja -
Ceragenin CSA-13 as free molecules and attached to magnetic nanoparticle surfaces induce caspase-dependent apoptosis in human breast cancer cells via disruption of cell oxidative balance
Publikacja -
Detection of DNA Replication Intermediates after Two-Dimensional Agarose Gel Electrophoresis Using a Fluorescein-Labeled Probe
Publikacja -
Synthetic analogues of cyanobacterial alkaloid cylindrospermopsin and their toxicological activity
Publikacja -
Characteristics of blond and red star ruby jaffa graefruits (citrus paradisi):results of the studies in vitro, in vivo and on patients suffering from atherosclerosis
PublikacjaCelem projektu, którego wyniki opisano w pracy byly badania dwóch odmian (jasna i czerwona) owoców grejfruta (in vitro i in vivo) stosowanych jako suplement diety pacjentów cierpiących na arterioskleroze. Stwierdzono, że zawartość związków bioaktywnych a w szczególności zwiazakow fenolowych i lepsze właściwosci przeciwutelniajace wykazuja owoce jasnej odmiany grajfruta. Stosowanie diety z dodatkiem owoców czerownego grejfruta w...
-
Multi-GPU-powered UNRES package for physics-based coarse-grained simulations of structure, dynamics, and thermodynamics of protein systems at biological size- and timescales
PublikacjaCoarse-grained models are nowadays extensively used in biomolecular simulations owing to the tremendous extension of size- and time-scale of simulations. The physics-based UNRES (UNited RESidue) model of proteins developed in our laboratory has only two interaction sites per amino-acid residue (united peptide groups and united side chains) and implicit solvent. However, owing to rigorous physics-based derivation, which enabled...