Wyszukiwarka
Wyniki wyszukiwania dla: HOMOCITRATE SYNTHASE GENE
-
Prognostic Significance of TOP2A Gene Dosage in HER-2-Negative Breast Cancer
Publikacja -
Germline mutations in theCHEK2 kinase gene are associated with an increased risk of bladder cancer
Publikacja -
Cloning of the thermostable alpha-amylase gene from Pyrococcus woesei in Escherichia coli.
PublikacjaGen kodujący alfa-amylazę z Pyrococcus woesei klonowano do plazmidów pET21d(+)lub pYTB2, którymi transformowano komórki Escherichia coli. Otrzymana rekombinantowa alfa amylaza wykazuje maksymalną aktywność przy pH 5.6 w temperaturze 95 stC i przejawia około 24 % początkowej aktywności nawet po 2 godz. inkubacji w 120 stC. Duża termostabilność otrzymanego preparatu świadczy o jego przydatności do enzymatycznego upłynniania skrobi.
-
Gene set enrichment for reproducible science: comparison of CERNO and eight other algorithms
Publikacja -
Adaptive filtering of microarray gene expression data based on Gaussian mixture decomposition
Publikacja -
Proteins Structure Models in the Evaluation of Novel Variant (C.472_477del) in the MOCS2 Gene
Publikacja -
Optimised expression cassettes of hpt marker gene for biolistic transformation of Miscanthus sacchariflorus
Publikacja -
The Relationship Between Gene Polymorphisms and Dipping Profile in Patients With Coronary Heart Disease
Publikacja -
Relationship between polymorphism in the CRH gene and the traits of body conformation of Salers cows
Publikacja -
The role of FNDC5 gene expression in irisin level changes accompanying thyroid pathologies
Publikacja -
Research Trends of Vitamin D Metabolism Gene Polymorphisms Based on a Bibliometric Investigation
Publikacja -
Association of ENAM gene single nucleotide polymorphisms with dental caries in Polish children
Publikacja -
The role of TGF superfamily gene expression in the regulation of folliculogenesis and oogenesis in mammals: a review
Publikacja -
Molecular modelling of transition state analogue inhibitors of glucosamine-6-P synthase and glucose-6-P isomerase.
PublikacjaStruktura kompleksu 2-amino-2-deoksy-D-glucitolo-6-P (ADGP) z centrum aktywnym syntazy GlcN-6-P z E. coli została wykorzystAna jako punkt wyjścia do modelowania molekularnego analogów ADGP. Używając programu GROMOS96 wygenerowano konformacje analogów o najniższych energiach wewnętrznych, które następnie ''dokowano'' w centrum aktywnym enzymu. Dokonano syntezy wybranych związków i określono parametry kinetyczne i termodynamiczne...
-
Correction to “Emerging Anticancer Activity of Candidal Glucosamine-6-Phosphate Synthase Inhibitors upon Nanoparticle-Mediated Delivery”
Publikacja -
Crystallization and preliminary X-ray analysis of the isomerase domain of glucosamine-6-phosphate synthase from Candida albicans
PublikacjaSyntaza glukozamino-6-fosforanu (EC 2.6.1.16) katalizuje pierwszy, praktycznie nieodwracalny etap w szlaku biosyntezy heksozoamin, którego produktem końcowym jest UDP-GlcNAc, kluczowy substrat dla tworzenia ściany komórkowej drobnoustrojów. Otrzymano kryształy domeny izomerazowej syntazy GlcN-6-P z Candida albicans, składającej się z reszt 346-712 (42 kDa). Analiza rentgenograficzna kryształu wykazała, że należy on do grupy przestrzennej...
-
Relationship between Telomere Length, TERT Genetic Variability and TERT, TP53, SP1, MYC Gene Co-Expression in the Clinicopathological Profile of Breast Cancer
PublikacjaThe molecular mechanisms of telomerase reverse transcriptase (TERT) upregulation in breast cancer (BC) are complex. We compared genetic variability within TERT and telomere length with the clinical data of patients with BC. Additionally, we assessed the expression of the TERT, MYC, TP53 and SP1 genes in BC patients and in BC organoids (3D cell cultures obtained from breast cancer tissues). We observed the same correlation in the...
-
Multiple transcriptional factors regulate transcription of the rpoE gene in Escherichia coli under different growth conditions and when the lipopolysaccharide biosynthesis is defective.
PublikacjaThe RpoE sigma factor is essential for the viability of Escherichia coli. RpoE regulates extracytoplasmic functions including lipopolysaccharide (LPS) translocation and some of its non-stoichiometric modifications. Transcription of the rpoE gene is positively autoregulated by EσE and by unknown mechanisms that control the expression of its distally located promoter(s). Mapping of 5′ ends of rpoE mRNA identified five new transcriptional...
-
Characteristics of the peanut chain in Europe – implications for peanut allergy
Publikacja -
Construction, purification, and functional characterization of His-tagged Candida albicans glucosamine-6-phosphate synthase expressed in Escherichia coli
Publikacja -
Prognostic Value of TOP2A Gene Amplification and Chromosome 17 Polysomy in Early Breast Cancer
Publikacja -
Molecular typing of Staphylococcus aureus based on PCR-RFLP of coa gene and RAPD analysis
Publikacja -
Sensitivity, Specificity and Prioritization of Gene Set Analysis When Applying Different Ranking Metrics
Publikacja -
Association between uridin diphosphate glucuronosylotranserase 1A1 (UGT1A1) gene polymorphism and neonatal hyperbilirubinemia
Publikacja -
Liver steatosis correlates with iron overload but not with HFE gene mutations in chronic hepatitis C
Publikacja -
Associations of ESR1 and ESR2 gene polymorphisms with metabolic syndrome and its components in postmenopausal women
Publikacja -
Cellular and Gene Expression Response to the Combination of Genistein and Kaempferol in the Treatment of Mucopolysaccharidosis Type I
Publikacja -
TGF-β gene polimorphisms as risk factors for asthma control among clinic patients
Publikacja -
TGF-β gene polimorphisms as risk factors for asthma control among clinic patients.
Publikacja -
TGF-β gene polimorphisms as risk factors for asthma control among clinic patients.
Publikacja -
Graphene-encapsulated iron nanoparticles as a non-viral vector for gene delivery into melanoma cells
Publikacja -
Metabolic Gene Expression in the Muscle and Blood Parameters of Broiler Chickens Stimulated In Ovo with Synbiotics
Publikacja -
Morphogenesis-related gene-expression profile in porcine oocytes before and after in vitro maturation
Publikacja -
The effects of p53 gene inactivation on mutant proteome expression in a human melanoma cell model
Publikacja -
Gene Therapy Approaches to Prevent Corneal Graft Rejection: Where Do We Stand?
Publikacja -
Genetic and structural characterization of the growth hormone gene and protein from tench, Tinca tinca
Publikacja -
The carbon source-dependent pattern of antimicrobial activity and gene expression in Pseudomonas donghuensis P482
Publikacja -
Branched-chain fatty acids affect the expression of fatty acid synthase and C-reactive protein genes in the hepatocyte cell line
Publikacja -
Single nucleotide polymorphisms in A4GALT spur extra products of the human Gb3/CD77 synthase and underlie the P1PK blood group system
Publikacja -
HIF1A, EPAS1, and VEGFA: angiogenesis and hypoxia-related gene expression in endometrium and endometrial epithelial tumors
Publikacja -
p53 Gene status in relation to ex vivo chemosensitivity of non-small cell lung cancer
Publikacja -
A new potential mode of cardiorenal protection of KLOTHO gene variability in type 1 diabetic adolescents
Publikacja -
Antioxidative enzymes and expression of rbcL gene as tools to monitor heavy metal-related stress in plants
Publikacja -
Application of PCR-HRM method for microsatellite polymorphism genotyping in the LDHA gene of pigeons (Columba livia)
Publikacja -
Correlation of Polymorphism of AQP7 Gene with the Sperm Cells Quality Traits of the Polish Holstein Friesian Bulls
Publikacja -
P-666 Detecting gene variants correlated with MII oocytes developed during ovarian stimulation
Publikacja -
Single median maxillary central incisor syndrome and variant in SMO gene associated with SHH pathway
Publikacja -
Analysis of miRNA expression associated with gene Lr34 responsible for resistance mechanisms to wheat leaf rust
Publikacja -
Novel method of expression and purification of hirudin based on pBAD TOPO, pTYB12 vectors and gene synthesis
PublikacjaW pracy przedstawiono nową, szybką i tanią metodę otrzymywania, ekspresji i oczyszczania białka hirudyny naturalnie izolowanego z ślinianek pijawki lekarskiej. Hirudyna pełni funkcje bezpośredniego inhibitora trombiny, głównego białka biorącego udział w tworzeniu skrzepów krwi. Właściwości te wykorzystywane są od wielu lat w klinice. Opracowana metoda pozwoliła uzyskać 17 mg/l hodowli E. coli białka o wysokiej czystości i aktywności...
-
Role of miR-15b/16–2 cluster network in endometrial cancer: An in silico pathway and prognostic analysis
PublikacjaEndometrial cancer (EC) is the second most common cancer in women. A large number of human cancers exhibit dysregulation of microRNA expression including EC. MiR-15b/16–2 is one of the best-known miRNA clusters that is expressed in many types of cancer tissues. Herein, we analyzed the expression of individual miR-15b/16–2 cluster members, its paralogues, and their target network analysis, as well as their prognostic significance...