Wyszukiwarka
Wyniki wyszukiwania dla: ONCOLOGY
-
Why they want to be treated in clinical trial -fundamental reasons of patient's decision
Publikacja -
PUB073 Lung Cancer Screening with LDCT – Results of a Small Cohort Continual Monitoring (Pilot Silesian Study)
Publikacja -
P3.13-032 The Impact of Tobacco Exposure on Lung Nodules and Emphysema in a Pilot Silesian Study of Early Lung Cancer with LDCT
Publikacja -
Retrospective assessment of Lung-RADS® performance in the Silesian Lung Cancer Screening Pilot Study
Publikacja -
The prognostic role of p53 and its correlation with CDK9 in urothelial carcinoma
Publikacja -
Longitudinal drug synergy assessment using convolutional neural network image-decoding of glioblastoma single-spheroid cultures
PublikacjaAbstract Background In recent years, drug combinations have become increasingly popular to improve therapeutic outcomes in various diseases, including difficult to cure cancers such as the brain cancer glioblastoma. Assessing the interaction between drugs over time is critical for predicting drug combination effectiveness and minimizing the risk of therapy resistance. However, as viability readouts of drug combination experiments...
-
Screening of predicted synergistic multi-target therapies in glioblastoma identifies new treatment strategies
PublikacjaAbstract Background IDH-wildtype glioblastoma (GBM) is a highly malignant primary brain tumor with a median survival of 15 months after standard of care, which highlights the need for improved therapy. Personalized combination therapy has shown to be successful in many other tumor types and could be beneficial for GBM patients. Methods We performed the largest drug combination screen to date in GBM, using a high-throughput effort...
-
C-reactive protein as a diagnostic and prognostic factor of endometrial cancer
Publikacja -
Multicentre, Prospective Observational Study of Pegfilgrastim Primary Prophylaxis in Patients at High Risk of Febrile Neutropenia in Poland: PROFIL Study
Publikacja -
The use of Yttrium-90 Ibritumomab Tiuxetan ( 90 Y-IT) as a consolidation therapy in high-risk patients with diffuse large B-cell lymphoma ineligible for autologous stem-cell transplantation
Publikacja -
Primary mediastinal B-cell lymphoma – metabolic and anatomical features in 18FDG-PET/CT and response to therapy
Publikacja -
Can we obtain planning goals for conformal techniques in neoadjuvant and adjuvant radiochemotherapy for gastric cancer patients?
Publikacja -
Preclinical [18F]tetrafluoroborate-PET/CT imaging of pituitary gland hyperplasia
Publikacja -
Reviews Palliative care in patients with lung cancer
Publikacja -
Dejection and self-assessment of quality of life in patients with lung cancer subjected to palliative care
Publikacja -
Selected aspects of palliative care and quality of life at the terminal stage of neoplastic disease
Publikacja -
Sense of coherence and acceptance of the disease in patients with lung cancer during palliative chemotherapy
Publikacja -
A 10-Year-old Girl With Late Acute Lymphoblastic Leukemia Recurrence Diagnosed With COVID-19 and Treated With Remdesivir
Publikacja -
292. Cisplatin and 5-fluorouracil in recurrent, persistent or metastatic cervical carcinoma
Publikacja -
Clinical Presentation of Herpes Zoster in Immunocompetent and Immunocompromised Hospitalized Children Treated With Acyclovir
Publikacja -
LanroNET, a non-interventional, prospective study to assess the resource utilization and cost of lanreotide autogel 120 mg in Polish patients with neuroendocrine tumors – results of interim analysis
Publikacja -
260. The role of patients and doctors in making decisions about the choice of the kind of adjuvant treatment in early brest cancer
Publikacja -
Triazoloacridone C-1305 abrogates the restriction checkpoint in cells lacking functional p53 and promotes their accumulation in the G2/M phase of the cell cycle
PublikacjaTriazoloakrydon C-1305, nowy inhibitor topoizomerazy II, wykazuje wysoką aktywość cytotoksyczną wobec komórek wielu typów nowotworów. Komórki mysie pozbawione genu PARP-1 wykazywały nadwrażliwość na działanie tego związku. W pracy testowaliśmy działanie związku wobec dwóch różnych komóek nowotworowych różniących się statusem p53: komórkami białaczki myelocytarnej HL-60 i raka sutka MCF-7. Wykazaliśmy, że inkubacja ze związkiem...
-
Physical activity, life satisfaction and adjustment to illness in women after treatment of breast cancer
Publikacja -
Notch signalling pathway as an oncogenic factor involved in cancer development
Publikacja -
Psychological adjustment of women after oncological surgery and at the end of treatment
Publikacja -
The role of Snail1 transcription factor in colorectal cancer progression and metastasis
Publikacja -
Gene copy numbers of HER family in breast cancer
Publikacja -
p53 Gene status in relation to ex vivo chemosensitivity of non-small cell lung cancer
Publikacja -
Extracellular matrix metalloproteinase inducer (EMMPRIN) expression correlates positively with active angiogenesis and negatively with basic fibroblast growth factor expression in epithelial ovarian cancer
Publikacja -
Antitumor Activity of Triazine Mimic Antibiotics for DNA-binding Implications (Impressive Activity in Vitro Against a Variety of Tumor Types in the NCI-60 Screen): NSC 710607 To Fight HCT-116 Human Colon Carcinoma Cell Lines in Vivo Using the Hollow Fiber Assay and Xenograft Mouse Models
PublikacjaPurpose Successful clinical applications of DNA-directed selective cytotoxic agents disrupt the vital replication/transcription processes and ultimately lead to cancer cell death. This study aimed to examine the growth screen of two lead triazine compounds in a number of cell lines and xenografts and to develop anticancer agents with noncovalent binding affinity bringing fewer side effects. Methods The NCI initial hollow...
-
DNA methylation analysis of benign and atypical meningiomas: correlation between RUNX3 methylation and WHO grade
Publikacja -
TRF1 and TRF2: pioneering targets in telomere-based cancer therapy
PublikacjaThis article presents an in-depth exploration of the roles of Telomere Repeat-binding Factors 1 and 2 (TRF1 and TRF2), and the shelterin complex, in the context of cancer biology. It emphasizes their emerging significance as potential biomarkers and targets for therapeutic intervention. Central to the shelterin complex, TRF1 and TRF2 are crucial in maintaining telomere integrity and genomic stability, their dysregulation often...
-
Cancer immune escape: the role of antigen presentation machinery
PublikacjaThe mechanisms of antigen processing and presentation play a crucial role in the recognition and targeting of cancer cells by the immune system. Cancer cells can evade the immune system by downregulating or losing the expression of the proteins recognized by the immune cells as antigens, creating an immunosuppressive microenvironment, and altering their ability to process and present antigens. This review focuses on the mechanisms...
-
Novel therapeutic compound acridine–retrotuftsin action on biological forms of melanoma and neuroblastoma
PublikacjaPURPOSE: As a continuation of our search for anticancer agents, we have synthesized a new acridine-retrotuftsin analog HClx9-[Arg(NO2)-Pro-Lys-Thr-OCH3]-1-nitroacridine (named ART) and have evaluated its activity against melanoma and neuroblastoma lines. Both tumors develop from cells (melanocytes, neurons) of neuroectodermal origin, and both are tumors with high heterogeneity and unsatisfactory susceptibility to chemotherapies....
-
Serum MicroRNAs as Xerostomia Biomarkers in Patients With Oropharyngeal Cancer Undergoing Radiation Therapy
Publikacja -
Circulating microRNAs as Biomarkers of Radiation Exposure: A Systematic Review and Meta-Analysis
Publikacja -
Radiation Therapy–Related Changes in Serum Proteome and Lipidome Are Primarily Associated With a Type of Acute Toxicity: Comparison of Radiation-Induced Effects in Patients Treated Because of Head and Neck Cancer or Prostate Cancer
Publikacja -
Radiation Therapy-Related Changes in Serum Proteome Patterns Are Affected by Medium Doses of Radiation Delivered to Large Volumes of Normal Tissue
Publikacja -
Radiation Therapy-Induced Changes in Serum Lipidome of Head and Neck Cancer Patients
Publikacja -
Bystander Effects Induced by Medium From Irradiated Cells: Similar Transcriptome Responses in Irradiated and Bystander K562 Cells
Publikacja -
Serum Proteome Signature of Radiation Response: Upregulation of Inflammation-Related Factors and Downregulation of Apolipoproteins and Coagulation Factors in Cancer Patients Treated With Radiation Therapy—A Pilot Study
Publikacja -
Potential of Serum Proteome Patterns Analysis by MALDI-TOF Mass Spectrometry for Prediction of Acute Radiation Injury Response in Head and Neck Cancers Patients
Publikacja -
Radiation-related Changes in Serum Proteome Profiles Detected by Mass Spectrometry in Blood of Patients Treated with Radiotherapy Due to Larynx Cancer
Publikacja -
Three-dimensional visualization and measurement of conformal dose distributions using magnetic resonance imaging of bang polymer gel dosimeters
Publikacja -
Image registration of BANG® gel dose maps for quantitative dosimetry verification
Publikacja -
Stanisław Łącki-Zynzeling
Osoby -
Joanna Rymaszewska prof. dr hab. n. med.
OsobyCV Joanna Rymaszewska Wroclaw University of Science and Technology, Wroclaw, Poland +48 601 98 26 24, joanna.rymaszewska@pwr.edu.pl orcid.org/0000-0001-8985-3592 2023 → Professor of Wroclaw University of Science and Technology (WUST), Poland 2011 → 2023 Professor of Wroclaw Medical University (WMU), PL 2016 → 2022 Head of the Department of Psychiatry, Wroclaw Medical University 2016 → 2022 Head of the Clinic of Psychiatry,...
-
Jaroslaw Spychala dr
OsobyOprócz bardzo dobrego wykształcenia osoba posiada również wieloletnie doświadczenie zawodowe, które jest poświadczeniem tego, że potrafi wykorzystać swoją wiedzę teoretyczną w praktycznych działaniach. Doświadczenie zawodowe jest bardzo bogate i rozbudowane. Ze względu na nabyte całkiem nowe umiejętności zwiększa się atrakcyjność doświadczonego pracownika. Są to między innymi kreatywne myślenie, zorientowanie na cel, odporność...
-
Clinical situations text database for Polish language
Dane BadawczeDataset contains a database of anonymized texts in Polish for the purposes of building a medical speech corpus, for clinical situations in the following areas: medical interview, interview and description of the result of an oncological examination, description of a radiological examination, description of a pathomorphological examination, description...