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Cell Adhesion & Migration
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Journal of Cell Death
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Methods in Cell Biology
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NATURE CELL BIOLOGY
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JOURNAL OF CELL SCIENCE
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Cell Death Discovery
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JOURNAL OF CELL BIOLOGY
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MOLECULAR BIOLOGY OF THE CELL
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Stem Cell Research
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TRENDS IN CELL BIOLOGY
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Dual-Activity Fluoroquinolone-Transportan 10 Conjugates offer alternative Leukemia therapy during Hematopoietic Cell Transplantation
PublikacjaHematopoietic cell transplantation (HCT) is often considered a last resort leukemia treatment, fraught with limited success due to microbial infections, a leading cause of mortality in leukemia patients. To address this critical issue, we explored a novel approach by synthesizing antileukemic agents containing antibacterial substances. This innovative strategy involves conjugating fluoroquinolone antibiotics, such as ciprofloxacin...
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Imunofan—RDKVYR Peptide—Stimulates Skin Cell Proliferation and Promotes Tissue Repair
PublikacjaRegeneration and wound healing are vital to tissue homeostasis and organism survival. One of the biggest challenges of today’s science and medicine is finding methods and factors to stimulate these processes in the human body. Effective solutions to promote regenerative responses will accelerate advances in tissue engineering, regenerative medicine, transplantology, and a number of other clinical specialties. In this study, we...
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Large cell acanthoma - Male, 63 - Tissue image [9270729565541501]
Dane BadawczeThis is the histopathological image of SKIN tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.
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Induced-fit binding of laccase to gold and carbon electrodes for the biological fuel cell applications
PublikacjaAnalogues of laccase natural substrates (syringic, veratric, ferulic, vanillic, isovanillic, 3,5-dimethoxybenzoic aldehydes) were employed to bind and orient laccase molecules in a way which facilitates adsorption of the catalyst molecules and their electrical connection with the conductive support. Laccase was bound efficiently to these substrates both on gold and carbon electrodes forming, respectively, 2D and 3D films sensitive...
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Clear cell acanthoma - Male, 57 - Tissue image [6190730017335231]
Dane BadawczeThis is the histopathological image of SKIN tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.
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Improved cytotoxicity and preserved level of cell death induced in colon cancer cells by doxorubicin after its conjugation with iron-oxide magnetic nanoparticles
PublikacjaA promising strategy for overcoming the problem of limited efficacy in antitumor drug delivery and in drug release is the use of a nanoparticle-conjugated drug. Doxorubicin (Dox) anticancer chemotherapeutics has been widely studied in this respect, because of severe cardiotoxic side effects. Here, we investigated the cytotoxic effects, the uptake process, the changes in cell cycle progression and the cell death processes in the...
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Clear cell acanthoma - Male, 77 - Tissue image [6260730021886991]
Dane BadawczeThis is the histopathological image of SKIN tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.
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Imunofan - RDKVYR peptide - stimulates skin cell proliferation and promotes tissue repair
PublikacjaRegeneration and wound healing are vital to tissue homeostasis and organism survival. One of the biggest challenges of today's science and medicine is finding methods and factors to stimulate these processes in the human body. Effective solutions to promote regenerative responses will accelerate advances in tissue engineering, regenerative medicine, transplantology, and a number of other clinical...
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Exploring the Beam Squint Effects on Reflectarray Perfromance: A Comprehensive Analysis of the Specular and Scattered Reflection of the Unit Cell
PublikacjaIn this article, the phenomena of beam deviation in reflectarray is discussed. The radiation pattern of the unit cell, which plays a vital role in shaping the beam of the reflectarray, is analyzed by considering undesired specular and scattered reflections. These unwanted reflections adversely affect the pattern of the single unit cell, thereby reducing the overall performance of the reflectarray. To conduct our investigations,...
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9,10-Dioxoanthracenyldithiocarbamates effectively inhibit the proliferation of non-small cell lung cancer by targeting multiple protein tyrosine kinases
PublikacjaAnthraquinones have attracted considerable interest in the realm of cancer treatment owing to their potent anticancer properties. This study evaluates the potential of a series of new anthraquinone derivatives as anticancer agents for non-small-cell lung cancer (NSCLC). The compounds were subjected to a range of tests to assess their cytotoxic and apoptotic properties, ability to inhibit colony formation, pro-DNA damage functions,...
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Cell-Based Therapies with T Regulatory Cells
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Glucose/O2 biofuel cell to generate electricity
PublikacjaOgniwa paliwowe mogą stanowić jedną z głównych technologii do produkowania energii w przyszłości. Pozwalają na uzyskanie energii elektrycznej i ciepła bezpośrednio z zachodzącej w nich reakcji chemicznej. Glukoza utleniana jest do glukonolaktonu przez enzym Glucose Oxidase, który jest immobilizowany ze specyficznym mediatorem na anodzie, podczas gdy tlen jest redukowany do wody za pomocą enzymu Laccase zimmobilizowanego ze specyficznym...
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Estrogen Receptors in Cell Membranes: Regulation and Signaling
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Postibrutinib outcomes in patients with mantle cell lymphoma
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Use of acalabrutinib in patients with mantle cell lymphoma
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Age-structured population model of cell survival
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Performance of the methanol PEM fuel cell module
PublikacjaPrzedstawiono charakterystyki układu zasilania składającego się z dwóch ogniw paliwowych o mocy 1.2 kW każde. Układ był zasilany metanolem, który podlegał procesowi reformowania w reformerze firmy Genesis Fueltech. Sprawność reformera wzrastała od 33% dla obciążenia minimalnego do 78% przy obciążeniu maksymalnym. Czystość uzyskiwanego wodoru była satysfakcjonująca w całym zakresie pracy reformera.
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The DAZgene expression in Sertoli cell only syndrome
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Cellular Interactions in the Intestinal Stem Cell Niche
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Quality inspection system in flexible manufacturing cell.
PublikacjaPublikacja dotyczy struktury procesu produkcyjnego w środowisku komputerowo zintegrowanego wytwarzania (computer integrated manufacturing - CIM). Ukazuje ona aspekty kontroli jakości wykonania części na różnych etapach procesu wytwórczego, podkreślając jego istotność. W celu dokonania szczegółowej analizy problemu zebrano dane o jakości wykonania części na poszczególnych poziomach wytwarzania. Analizy dowiodły, że jakość wykonania...
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Evolution of chemotaxis in single-cell artificial organisms
PublikacjaThe model of a liquid two-dimensional environment, which is based on physics of diffusion, allows us to simulate the diffusion of morphogenes. Artificial organisms move using a chemotaxis reacting to concentration difference. Organisms are controlled by a gene regulatory network coded in a linear genome and reproduce by division. We made a lot of experiments presenting organisms’ behaviour in various environment conditions. We...
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Electrochemically assisted deposition of hydroxyapatite on Ti6Al4V substrates covered by CVD diamond films — Coating characterization and first cell biological results
PublikacjaAlthough titaniumand its alloys are widely used as implant material for orthopedic and dental applications they show only limited corrosion stability and osseointegration in different cases. The aim of the presented research was to develop and characterize a novel surface modification system from a thin diamond base layer and a hydroxyapatite (HAp) top coating deposited on the alloy Ti6Al4V widely used for implants in contact with bone....
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Inhibition of ALDH1A1 activity decreases expression of drug transporters and reduces chemotherapy resistance in ovarian cancer cell lines
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Squamous intraepithelial neoplasia, grade III - Female, 45 - Tissue image [529073002551401]
Dane BadawczeThis is the histopathological image of CORPUS UTERI tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 1000 slide scanner (20x magnification) and saved to DICOM format.
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Squamous intraepithelial neoplasia, grade III - Female, 45 - Tissue image [5290730025514291]
Dane BadawczeThis is the histopathological image of CORPUS UTERI tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 1000 slide scanner (20x magnification) and saved to DICOM format.