Filtry
wszystkich: 8847
-
Katalog
- Publikacje 6517 wyników po odfiltrowaniu
- Czasopisma 272 wyników po odfiltrowaniu
- Konferencje 10 wyników po odfiltrowaniu
- Wydawnictwa 3 wyników po odfiltrowaniu
- Osoby 93 wyników po odfiltrowaniu
- Wynalazki 5 wyników po odfiltrowaniu
- Projekty 5 wyników po odfiltrowaniu
- Kursy Online 81 wyników po odfiltrowaniu
- Wydarzenia 5 wyników po odfiltrowaniu
- Dane Badawcze 1856 wyników po odfiltrowaniu
wyświetlamy 1000 najlepszych wyników Pomoc
Wyniki wyszukiwania dla: PSORIASIS GENETICS, GWAS, EPIGENETIC CHANGES, MIRNA
-
Impact of isoflavone genistein on psoriasis in in vivo and in vitro investigations
Publikacja -
Serum fatty acid profile in psoriasis and its comorbidity
Publikacja -
Serum YKL-40 as a potential biomarker of inflammation in psoriasis
Publikacja -
Effect of psoriasis activity on serum adiponectin and leptin levels
Publikacja -
Role of omentin and vaspin in metabolic diseases in association with psoriasis
Publikacja -
Enigmatic 5-hydroxymethyluracil: Oxidatively modified base, epigenetic mark or both?
Publikacja -
Revealing the epigenetic effect of temozolomide on glioblastoma cell lines in therapeutic conditions
Publikacja -
Epigenetic inhibitor zebularine activates ear pinna wound closure in the mouse
PublikacjaBackground:Most studies on regenerative medicine focus on cell-based therapies and transplantations.Small-molecule therapeutics, though proved effective in different medical conditions, have not been extensivelyinvestigated in regenerative research. It is known that healing potential decreases with development and devel-opmental changes are driven by epigenetic mechanisms, which suggests epigenetic repression of regenerativecapacity.Methods:We...
-
Activation of endogenous regenerative potential in mammals using epigenetic inhibitor zebularine
PublikacjaIn this work, a nucleoside inhibitor of DNA methyltransferases, zebularine, was investigated as a wound healing and regeneration promoting agent. It was found that a high dose of intraperitoneally delivered zebularine improved punch wound closure in the ear pinna in mice. Both cytidine, a zebularine analogue, and uridine, a zebularine metabolite, did not promote ear pinna hole closure. The effect of zebularine on ear pinna healing...
-
Epigenetic regulation and regeneration: the search for differentially methylated genes in the MRL mouse
PublikacjaThe MRL mouse is an inbred laboratory strain, which was developed in the 60’s of the 20th century and has been extensively used as a model of lupus erythematosus. The regenerative abilities of the strain were discovered in the 90' when the MRL mouse was shown to close 2 mm hole punches made in the ear pinnae four weeks after injury without scarring. The phenomenon has not been observed in other mouse strains, where the holes...
-
Properties of a lithium solid electrolyte gas sensor based on reaction kinetics
PublikacjaW artykule przedstawiono zasadę działania, budowę i właściwości czujnika gazu na bazie elektrolitu stałego z mobilnymi jonami litu. Czujnik został przygotowany w technologii grubowarstwowej. Przedstawiono wyniki badań czujnika w mieszaninach gazów toksycznych.
-
Susceptibility of the LLC Resonance Generator for Induction Heating on Changes in Load Parameters Caused by Heating the Charge
Publikacja -
Significance of selected inflammatory factors in metabolic disorders in association with psoriasis
Publikacja -
Examination of epigenetic inhibitor zebularine in treatment of skin wounds in healthy and diabetic mice
PublikacjaDNA methyltransferase inhibitor zebularine was proven to induce regeneration in the ear pinna in mice. We utilized a dorsal skin wound model to further evaluate this epigenetic inhibitor in wound healing. Full-thickness excisional wounds were made on the dorsum of 2 and 10-month-old healthy BALB/c and 3 and 8-month-old diabetic (db/db) mice, followed by topical or intraperitoneal zebularine delivery. Depending on the strain, age,...
-
Transcriptional activity of epigenetic remodeling genes declines in keratinocytes after in vitro expansion
PublikacjaPURPOSE: In vitro expansion is an invaluable method to obtain keratinocytes in amounts necessary for effective transplantation therapies. In vitro cell culturing provokes questions concerning potential epigenetic alterations occurring in expanded cells in the context of usefulness for transplantation and safety. The purpose of this study was to investigate as to whether keratinocyte expansion is associated with changes in the activity...
-
The influence of pre- and postharvest treatments on selected biological and epigenetic activities of Brassica sprouts
PublikacjaIntroduction The Brassica vegetables are rich in glucosinolates (GLs), which are enzymatically hydrolysed to bioactive isothiocynates (ITC) and indoles, regarded as the most promising chemopreventing agents. However, in the majority of brassica sprouts the GL conversion into these beneficial derivatives occurs at the level of about 1 %, while in cabbage leaves exceeds 70%. Since sprouts represent plant material, which is frequently...
-
TLC-based detection of methylated cytosine: application to aging epigenetics
Publikacja -
Potential of Liquid Biopsy in Papillary Thyroid Carcinoma in Context of miRNA, BRAF and p53 Mutation
Publikacja -
Is the Identification of SNP-miRNA Interactions Supporting the Prediction of Human Lymphocyte Transcriptional Radiation Responses?
Publikacja -
Salt Stress Reveals a New Role for ARGONAUTE1 in miRNA Biogenesis at the Transcriptional and Posttranscriptional Levels
Publikacja -
Assessment of Life Quality, Stress and Physical Activity Among Patients with Psoriasis
Publikacja -
Effect of psoriasis activity and topical treatment on serum lipocalin-2 levels
Publikacja -
Serum Fatty Acid-Binding Protein 4 is Increased in Patients with Psoriasis
Publikacja -
Epigenetic modifications and NF-κB pathway activity in Cu,Zn-SOD-deficient mice
Publikacja -
Epigenetic Basis of Regeneration: Analysis of Genomic DNA Methylation Profiles in the MRL/MpJ Mouse
PublikacjaEpigenetic regulation plays essential role in cell differentiation and dedifferentiation, which are the intrinsic processes involved in regeneration. To investigate the epigenetic basis of regeneration capacity, we choose DNA methylation as one of the most important epigenetic mechanisms and the MRL/MpJ mouse as a model of mammalian regeneration known to exhibit enhanced regeneration response in different organs. We report the...
-
GENETICA
Czasopisma -
BEHAVIOR GENETICS
Czasopisma -
CURRENT GENETICS
Czasopisma -
BMC GENETICS
Czasopisma -
Cytology and Genetics
Czasopisma -
CLINICAL GENETICS
Czasopisma -
Community Genetics
Czasopisma -
Cancer Genetics
Czasopisma -
BIOCHEMICAL GENETICS
Czasopisma -
CONSERVATION GENETICS
Czasopisma -
AIMS Genetics
Czasopisma -
Frontiers in Genetics
Czasopisma -
Genetics Research
Czasopisma -
GENETICS IN MEDICINE
Czasopisma -
PLOS Genetics
Czasopisma -
Advances in Genetics
Czasopisma -
Ecological Genetics
Czasopisma -
Investigative Genetics
Czasopisma -
Neurology-Genetics
Czasopisma -
PSYCHIATRIC GENETICS
Czasopisma -
Advanced Genetics
Czasopisma -
ANIMAL GENETICS
Czasopisma -
OBM Genetics
Czasopisma -
OPHTHALMIC GENETICS
Czasopisma -
JOURNAL OF GENETICS
Czasopisma