Wyniki wyszukiwania dla: F1-ATPASE
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Novel 5-Substituted 2-(Aylmethylthio)-4-chloro-N-(5-aryl-1,2,4-triazin-3-yl)benzenesulfonamides: Synthesis, Molecular Structure, Anticancer Activity, Apoptosis-Inducing Activity and Metabolic Stability
PublikacjaA series of novel 5-substituted 2-(arylmethylthio)-4-chloro-N-(5-aryl-1,2,4-triazin-3-yl) benzenesulfonamide derivatives 27–60 have been synthesized by the reaction of aminoguanidines with an appropriate phenylglyoxal hydrate in glacial acetic acid. A majority of the compounds showed cytotoxic activity toward the human cancer cell lines HCT-116, HeLa and MCF-7, with IC50 values below 100 M. It was found that for the analogues 36–38...
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CYP3A4 overexpression enhances apoptosis induced by anticancer agent imidazoacridinone C-1311, but does not change the metabolism of C-1311 in CHO cells
PublikacjaWe examine whether CYP3A4 overexpression influences the rate and pattern of antitumor imidazoacridinone C-1311 metabolism, in relation to the impact of this overexpression on cell cycle progression and final cellular response of CHO cells following C-1311 treatment. Methods: Three CHO cell lines: CHO-WT, wild type, CHO-HR, overexpressing cytochrome P450 reductase (CPR) and CHO-HR-3A4, coexpressing CPR and CYP3A4 were applied....
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Mechanical and structural investigations of wings of selected insect species
PublikacjaThis paper presents research and measurements leading to obtaining the Young’s modulus of wing bearing structures of selected insect species. A small testing machine intended for three-point bending and equipped with instruments registering low forces was constructed for the needs of the experiment. The machine was used to perform numerous bending tests of wings of three species of insects (obtained from a breeding farm): Attacus...
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Design and computational fluid dynamics analysis of the last stage of innovative gas-steam turbine
PublikacjaResearch regarding blade design and analysis of flow has been attracting interest for over a century. Meanwhile new concepts and design approaches were created and improved. Advancements in information technologies allowed to introduce computational fluid dynamics and computational flow mechanics. Currently a combination of mentioned methods is used for the design of turbine blades. These methods enabled us to improve flow efficiency...
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Impedance spectra of ZnO varistor type 280 model O M ver. 89
Dane BadawczeThe impedance spectrum of high-voltage ZnO varistor obtained using FRA EIS impedance spectrosocpy measurement method. The 1V sinusoidal excitation was used. The frequency range was chosen from 10 kHz down to 100 uHz. The object under test and the measuring instrument were placed in a Faraday cage due to high impedance of the object. The data was acquired...
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Human UDP-Glucuronosyltransferases: Effects of altered expression in breast and pancreatic cancer cell lines.
PublikacjaIncreased aerobic glycolysis and de novo lipid biosynthesis are common characteristics of invasive cancers. UDP-glucuronosyltransferases (UGTs) are phase II drug metabolizing enzymes that in normal cells possess the ability to glucuronidate these lipids and speed their excretion; however, de-regulation of these enzymes in cancer cells can lead to an accumulation of bioactive lipids, which further fuels cancer progression. We hypothesize...
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A standardised static in vitro digestion method suitable for food – an international consensus
PublikacjaSimulated gastro-intestinal digestion is widely employed in many fields of food and nutritional sciences, as conducting human trials are often costly, resource intensive, and ethically disputable. As a consequence, in vitro alternatives that determine endpoints such as the bioaccessibility of nutrients and non-nutrients or the digestibility of macronutrients (e.g. lipids, proteins and carbohydrates) are used for screening and building...
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Rate performance of (NH4)2V10O25·8H2O as cathode material in Li-ion batteries
Dane BadawczeThe DataSet contains the galvanostatic charge/discharge curves of the ammonium vanadate nanostructures obtained by the hydrothermal method under an initial pressure of 50 bar ((NH4)2V10O25·8H2O). The battery tests of the samples were performed using the ATLAS 0961 MBI multichannel battery testing system with different current densities in the voltage...
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Rate performance of mixture (NH4)2V6O16 and (NH4)2V10O25·8H2O as cathode material in Li-ion batteries
Dane BadawczeThe DataSet contains the galvanostatic charge/discharge curves of the ammonium vanadate nanostructures obtained by the hydrothermal method without initial pressure (mixture (NH4)2V6O16 and (NH4)2V10O25·8H2O). The battery tests of the samples were performed using the ATLAS 0961 MBI multichannel battery testing system with different current densities...
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PARP inhibition potentiates the cytotoxic activity of C-1305, a selective inhibitor of topoisomerase II, in human BRCA1-positive breast cancer cells
PublikacjaTwo cellular proteins encoded by the breast and ovarian cancer type 1 susceptibility (BRCA1 and BRCA2) tumor suppressor genes are essential for DNA integrity and the maintenance of genomic stability.Approximately 5-10% of breast and ovarian cancers result from inherited alterations or mutations in these genes.Remarkably, BRCA1/BRCA2-deficient cells are hypersensitive to selective inhibition of poly(ADPribose) polymerase 1 (PARP-1),...
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On design and analysis of flow characteristics of the last stage of gas-steam turbine
PublikacjaResearch regarding blade design and analysis of flow have been conducted for over a century. Meanwhile new concepts and design approaches were created and improved. Advancements in information technologies allowed to introduce computational fluid dynamics (CFD) and computational flow mechanics (CFM). Currently a combination of mentioned methods is used for design of turbine blades. These methods enabled us to improve flow efficiency...
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Targeting of FLT3-ITD kinase contributes to high selectivity of imidazoacridinone C-1311 against FLT3-activated leukemia cells
PublikacjaDrugs targeting receptor tyrosine kinase FLT3 are of particular interest since activating FLT3-internal tandem duplication (ITD) mutations abundantly occur in fatal acute myeloid leukemias (AMLs). Imidazoacridinone C-1311, a DNA-reactive inhibitor of topoisomerase II, has been previously shown to be a potent and selective inhibitor of recombinant FLT3. Here, we expand those findings by studying its effect on leukemia cells with...
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Novel therapeutic compound acridine–retrotuftsin action on biological forms of melanoma and neuroblastoma
PublikacjaPURPOSE: As a continuation of our search for anticancer agents, we have synthesized a new acridine-retrotuftsin analog HClx9-[Arg(NO2)-Pro-Lys-Thr-OCH3]-1-nitroacridine (named ART) and have evaluated its activity against melanoma and neuroblastoma lines. Both tumors develop from cells (melanocytes, neurons) of neuroectodermal origin, and both are tumors with high heterogeneity and unsatisfactory susceptibility to chemotherapies....
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Impedance spectra of ZnO varistor type 440 model A ver. M
Dane BadawczeThe impedance spectrum of high-voltage ZnO varistor obtained using FRA EIS impedance spectrosocpy measurement method. The 1V sinusoidal excitation was used. The frequency range was chosen from 10 kHz down to 100 uHz. The object under test and the measuring instrument were placed in a Faraday cage due to high impedance of the object. The data was acquired...
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Impedance spectra of ZnO varistor type 680 model A M ver. 93
Dane BadawczeThe impedance spectrum of high-voltage ZnO varistor obtained using FRA EIS impedance spectrosocpy measurement method. The 1V sinusoidal excitation was used. The frequency range was chosen from 10 kHz down to 100 uHz. The object under test and the measuring instrument were placed in a Faraday cage due to high impedance of the object. The data was acquired...
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Impedance spectra of ZnO varistor type 680 model O M ver. 65 13
Dane BadawczeThe impedance spectrum of high-voltage ZnO varistor obtained using FRA EIS impedance spectrosocpy measurement method. The 1V sinusoidal excitation was used. The frequency range was chosen from 10 kHz down to 100 uHz. The object under test and the measuring instrument were placed in a Faraday cage due to high impedance of the object. The data was acquired...
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Impedance spectra of ZnO varistor type 680 model A M ver. xx
Dane BadawczeThe impedance spectrum of high-voltage ZnO varistor obtained using FRA EIS impedance spectrosocpy measurement method. The 1V sinusoidal excitation was used. The frequency range was chosen from 10 kHz down to 100 uHz. The object under test and the measuring instrument were placed in a Faraday cage due to high impedance of the object. The data was acquired...
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Impedance spectra of ZnO varistor type 280 model A ver. M
Dane BadawczeThe impedance spectrum of high-voltage ZnO varistor obtained using FRA EIS impedance spectrosocpy measurement method. The 1V sinusoidal excitation was used. The frequency range was chosen from 10 kHz down to 100 uHz. The object under test and the measuring instrument were placed in a Faraday cage due to high impedance of the object. The data was acquired...
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Impedance spectra of ZnO varistor type 280 model 0 ver. 89
Dane BadawczeThe impedance spectrum of high-voltage ZnO varistor obtained using FRA EIS impedance spectrosocpy measurement method. The 1V sinusoidal excitation was used. The frequency range was chosen from 10 kHz down to 100 uHz. The object under test and the measuring instrument were placed in a Faraday cage due to high impedance of the object. The data was acquired...
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Impedance spectra of ZnO varistor type 280 model O ver. 68
Dane BadawczeThe impedance spectrum of high-voltage ZnO varistor obtained using FRA EIS impedance spectrosocpy measurement method. The 1V sinusoidal excitation was used. The frequency range was chosen from 100 kHz down to 100 uHz. The object under test and the measuring instrument were placed in a Faraday cage due to high impedance of the object. The data was acquired...
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Impedance spectra of ZnO varistor type 440 model O ver. 68
Dane BadawczeThe impedance spectrum of high-voltage ZnO varistor obtained using FRA EIS impedance spectrosocpy measurement method. The 1V sinusoidal excitation was used. The frequency range was chosen from 10 kHz down to 10 uHz. The object under test and the measuring instrument were placed in a Faraday cage due to high impedance of the object. The data was acquired...
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Impedance spectra of ZnO varistor type 680 model O M ver. 65 60
Dane BadawczeThe impedance spectrum of high-voltage ZnO varistor obtained using FRA EIS impedance spectrosocpy measurement method. The 1V sinusoidal excitation was used. The frequency range was chosen from 10 kHz down to 10 uHz. The object under test and the measuring instrument were placed in a Faraday cage due to high impedance of the object. The data was acquired...
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Pealizacija inicjatiw wostocznogo partnerstwa w Azerbajdżane
PublikacjaAzerbaijan established political relations with the EU during the implementation of TACIS Programme projects and signed the Partnership and Cooperation Agreement with the EU in 1996. It joined the European Neighbourhood Policy in 2004 and the Eastern Partnership programme in 2009. Despite the sceptical attitude taken by Azerbaijan's government towards the Eastern Partnership initiative, the EU earmarked further funds for Azerbaijan for 2011 – 2014 as part of the European Neighbourhood and Partnership Instrument. During the third Eastern Partnership summit in Vilnius in November 2013, Azerbaijan signed only an agreement concerning visa facilitations and readmission. However, it also undertook certain measures as part of the five Eastern Partnership initiatives. In the framework of the Integrated Border Management Programme, Azerbaijan implemented projects connected with improving the access of resettled people to the judicial system, creation of electronic border control systems, social protection, increasing public awareness to eliminate domestic violence, improving assimilation of asylum - seekers and immigrants, and supporting occupational health organisations. Activities aimed at supporting SMEs included training for entrepreneurs, promotional conferences and loans to the SME sector. Recommendations of the initiative promoting the creation of regional electrical and renewable energy markets were implemented by Azerbaijan in the form of 33 projects as part of the INOGATE Programme. With respect to environmental management, Azerbaijan developed a digital regional atlas of natural disasters, and with respect to natural disaster mitigation it planned population protection measures. Azerbaijan was ranked last but one in the evaluation presented in the annual report prepared by the EU. The transformation process in this country has been slow and illusory in certain aspects. Nevertheless, the EU has continued its Eastern Partnership initiative activities, allocating between EUR 252,000 and 308,000 for transformations in Azerbaijan
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The bile salt/phospholipid ratio determines the extent of in vitro intestinal lipolysis of triglycerides: Interfacial and emulsion studies
PublikacjaThis study focused on the protein-stabilised triglyceride (TG)/water interfaces and oil-in-water emulsions, and explored the influence of varying molar ratios of bile salts (BSs) and phospholipids (PLs) on the intestinal lipolysis of TGs. The presence of these two major groups of biosurfactants delivered with human bile to the physiological environment of intestinal digestion was replicated in our experiments by using mixtures...
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Electrochemical cell impedance spectra at Eoc+100mV
Dane BadawczeThe dataset presents impedance spectrum of electrochemical cell filled with 3% NaCl solution presented in the figure below. This cell was used measured using Atlas-Sollich 0531 impedance analyser with built-in potentiostat. When changing the DC polarisation of the cell the non-linear phenomena could be observed. The impedance spectrum frequency range...
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Electrochemical cell impedance spectra at Eoc+200mV
Dane BadawczeThe dataset presents impedance spectrum of electrochemical cell filled with 3% NaCl solution presented in the figure below. This cell was used measured using Atlas-Sollich 0531 impedance analyser with built-in potentiostat. When changing the DC polarisation of the cell the non-linear phenomena could be observed. The impedance spectrum frequency range...
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Testing high impedance analyzer in the field on high-voltage line pylon cell 1 exposition 2
Dane BadawczeThe dataset presents impedance spectrum of anticorrosion coating on high-voltage line pylon presented in the figure below. This object was used to test high-impedance analyzer for diagnostic of anticorossion coatings (HIADAC) realized in the frame of Eureka project E!3174. The dataset contains comparative measurements with Atlas-Sollich ATLAS98HI analyser....
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Testing high impedance analyzer in the field on high-voltage line pylon cell 1 exposition 1
Dane BadawczeThe dataset presents impedance spectrum of anticorrosion coating on high-voltage line pylon presented in the figure below. This object was used to test high-impedance analyzer for diagnostic of anticorossion coatings (HIADAC) realized in the frame of Eureka project E!3174. The dataset contains comparative measurements with Atlas-Sollich ATLAS98HI analyser....
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Electrochemical cell impedance spectra at Eoc-100mV
Dane BadawczeThe dataset presents impedance spectrum of electrochemical cell filled with 3% NaCl solution presented in the figure below. This cell was used measured using Atlas-Sollich 0531 impedance analyser with built-in potentiostat. When changing the DC polarisation of the cell the non-linear phenomena could be observed. The impedance spectrum frequency range...
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Electrochemical cell impedance spectra at Eoc
Dane BadawczeThe dataset presents impedance spectrum of electrochemical cell filled with 3% NaCl solution presented in the figure below. This cell was used measured using Atlas-Sollich 0531 impedance analyser with built-in potentiostat. When changing the DC polarisation of the cell the non-linear phenomena could be observed. The impedance spectrum frequency range...
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Testing high impedance analyzer in the field on high-voltage line pylon cell 2 exposition 1
Dane BadawczeThe dataset presents impedance spectrum of anticorrosion coating on high-voltage line pylon presented in the figure below. This object was used to test high-impedance analyzer for diagnostic of anticorossion coatings (HIADAC) realized in the frame of Eureka project E!3174. The dataset contains comparative measurements with Atlas-Sollich ATLAS98HI analyser....
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Electrochemical cell impedance spectra at Eoc-200mV
Dane BadawczeThe dataset presents impedance spectrum of electrochemical cell filled with 3% NaCl solution presented in the figure below. This cell was used measured using Atlas-Sollich 0531 impedance analyser with built-in potentiostat. When changing the DC polarisation of the cell the non-linear phenomena could be observed. The impedance spectrum frequency range...
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Thermographic imaging of electrochemical double layer capacitors during cycling charging - discharging 0 - 3,1 V at 420 mA. Sample 103.
Dane BadawczeDataset contains thermal images of prototype electrochemical double layer capacitor taken during cyclic charging - discharging. The sample was charged to 3,1 V and discharged to 10 mV by constant current 420 mA. Sample 103. Voltage was increased to accelerate the ageing process.The images were taken with thermographic camera VigoCAM V50. The sample...
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Thermographic imaging of electrochemical double layer capacitors during cycling charging - discharging 0 - 2,7 V at 732 mA. Sample J51.
Dane BadawczeDataset contains thermal images of prototype electrochemical double layer capacitor taken during cyclic charging - discharging. The sample was charged to 2,7 V and discharged to 10 mV by constant current 732 mA. Sample J51.The images were taken with thermographic camera VigoCAM V50. The sample was covered by black graphite paint to ensure uniform surface...
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Thermographic imaging of electrochemical double layer capacitors during cycling charging - discharging 0 - 2,7 V at 366 mA. Sample J51.
Dane BadawczeDataset contains thermal images of prototype electrochemical double layer capacitor taken during cyclic charging - discharging. The sample was charged to 2,7 V and discharged to 10 mV by constant current 366 mA. Sample J51.The images were taken with thermographic camera VigoCAM V50. The sample was covered by black graphite paint to ensure uniform surface...
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Thermographic imaging of electrochemical double layer capacitors during cycling charging - discharging 0 - 2,7 V at 534 mA. Sample J53, run #1.
Dane BadawczeDataset contains thermal images of prototype electrochemical double layer capacitor taken during cyclic charging - discharging. The sample was charged to 2,7 V and discharged to 10 mV by constant current 534 mA. Sample J53, experiment run #1. The images were taken with thermographic camera VigoCAM V50. The sample was covered by black graphite paint...
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Thermographic imaging of electrochemical double layer capacitors during cycling charging - discharging 0 - 2,7 V at 534 mA. Sample J53, run #4.
Dane BadawczeDataset contains thermal images of prototype electrochemical double layer capacitor taken during cyclic charging - discharging. The sample was charged to 2,7 V and discharged to 10 mV by constant current 534 mA. Sample J53, experiment run #4. The images were taken with thermographic camera VigoCAM V50. The sample was covered by black graphite paint...
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Thermographic imaging of electrochemical double layer capacitors during cycling charging - discharging 0 - 3,2 V at 420 mA. Sample 103.
Dane BadawczeDataset contains thermal images of prototype electrochemical double layer capacitor taken during cyclic charging - discharging. The sample was charged to 3,2 V and discharged to 10 mV by constant current 420 mA. Sample 103. Voltage was increased to accelerate the ageing process.The images were taken with thermographic camera VigoCAM V50. The sample...
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Thermographic imaging of electrochemical double layer capacitors during cycling charging - discharging 0 - 2,8 V at 420 mA. Sample 103.
Dane BadawczeDataset contains thermal images of prototype electrochemical double layer capacitor taken during cyclic charging - discharging. The sample was charged to 2,8 V and discharged to 10 mV by constant current 420 mA. Sample 103. Voltage was increased to accelerate the ageing process.The images were taken with thermographic camera VigoCAM V50. The sample...
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Thermographic imaging of electrochemical double layer capacitors during cycling charging - discharging 0 - 2,7 V at 1098 mA. Sample J51.
Dane BadawczeDataset contains thermal images of prototype electrochemical double layer capacitor taken during cyclic charging - discharging. The sample was charged to 2,7 V and discharged to 10 mV by constant current 1098 mA. Sample J51.The images were taken with thermographic camera VigoCAM V50. The sample was covered by black graphite paint to ensure uniform...
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Thermographic imaging of electrochemical double layer capacitors during cycling charging - discharging 0 - 2,7 V at 480 mA. Sample 103.
Dane BadawczeDataset contains thermal images of prototype electrochemical double layer capacitor taken during cyclic charging - discharging. The sample was charged to 2,7 V and discharged to 10 mV by constant current 480 mA. Sample 103. The images were taken with thermographic camera VigoCAM V50. The sample was covered by black graphite paint to ensure uniform...
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Thermographic imaging of electrochemical double layer capacitors during cycling charging - discharging 0 - 2,7 V at 915 mA. Sample J51.
Dane BadawczeDataset contains thermal images of prototype electrochemical double layer capacitor taken during cyclic charging - discharging. The sample was charged to 2,7 V and discharged to 10 mV by constant current 915 mA. Sample J51.The images were taken with thermographic camera VigoCAM V50. The sample was covered by black graphite paint to ensure uniform surface...
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Thermographic imaging of electrochemical double layer capacitors during cycling charging - discharging 0 - 2,7 V at 420 mA. Sample 103, run#2.
Dane BadawczeDataset contains thermal images of prototype electrochemical double layer capacitor taken during cyclic charging - discharging. The sample was charged to 2,7 V and discharged to 10 mV by constant current 420 mA. Sample 103, experiment run #2. The images were taken with thermographic camera VigoCAM V50. The sample was covered by black graphite paint...
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Thermographic imaging of electrochemical double layer capacitors during cycling charging - discharging 0 - 2,7 V at 108 mA. Sample J51.
Dane BadawczeDataset contains thermal images of prototype electrochemical double layer capacitor taken during cyclic charging - discharging. The sample was charged to 2,7 V and discharged to 10 mV by constant current 108 mA. Sample J51.The images were taken with thermographic camera VigoCAM V50. The sample was covered by black graphite paint to ensure uniform surface...
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Thermographic imaging of electrochemical double layer capacitors during cycling charging - discharging 0 - 2,7 V at 549 mA. Sample J51.
Dane BadawczeDataset contains thermal images of prototype electrochemical double layer capacitor taken during cyclic charging - discharging. The sample was charged to 2,7 V and discharged to 10 mV by constant current 549 mA. Sample J51.The images were taken with thermographic camera VigoCAM V50. The sample was covered by black graphite paint to ensure uniform surface...
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Thermographic imaging of electrochemical double layer capacitors during cycling charging - discharging 0 - 3,5 V at 420 mA. Sample 103.
Dane BadawczeDataset contains thermal images of prototype electrochemical double layer capacitor taken during cyclic charging - discharging. The sample was charged to 3,5 V and discharged to 10 mV by constant current 420 mA. Sample 103. Voltage was increased to accelerate the ageing process.The images were taken with thermographic camera VigoCAM V50. The sample...
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Thermographic imaging of electrochemical double layer capacitors during cycling charging - discharging 0 - 2,7 V at 420 mA. Sample 103, run#1.
Dane BadawczeDataset contains thermal images of prototype electrochemical double layer capacitor taken during cyclic charging - discharging. The sample was charged to 2,7 V and discharged to 10 mV by constant current 420 mA. Sample 103, experiment run #1. The images were taken with thermographic camera VigoCAM V50. The sample was covered by black graphite paint...
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Thermographic imaging of electrochemical double layer capacitors during cycling charging - discharging 0 - 2,75 V at 241 mA. Sample 24, run #3.
Dane BadawczeDataset contains thermal images of prototype electrochemical double layer capacitor taken during cyclic charging - discharging. The sample was charged to 2,75 V and discharged to 10 mV by constant current 241 mA, experiment run #3The images were taken with thermographic camera VigoCAM V50. The sample was covered by black graphite paint to ensure uniform...
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Thermographic imaging of electrochemical double layer capacitors during cycling charging - discharging 0 - 2,75 V at 241 mA. Sample 24, run #5.
Dane BadawczeDataset contains thermal images of prototype electrochemical double layer capacitor taken during cyclic charging - discharging. The sample was charged to 2,75 V and discharged to 10 mV by constant current 241 mA, experiment run #5.The images were taken with thermographic camera VigoCAM V50. The sample was covered by black graphite paint to ensure uniform...
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Thermographic imaging of electrochemical double layer capacitors during cycling charging - discharging 0 - 2,8 V at 241 mA. Sample 24, run #1.
Dane BadawczeDataset contains thermal images of prototype electrochemical double layer capacitor taken during cyclic charging - discharging. The sample was charged to 2,8 V and discharged to 10 mV by constant current 241 mA, experiment run #1.The images were taken with thermographic camera VigoCAM V50. The sample was covered by black graphite paint to ensure uniform...