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Development of sensitive cathepsin G fluorogenic substrate using combinatorial chemistry methods
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Photophysics of 7-Hydroxytetrahydroisoquinoline-3-carboxylic Acid and Its Derivatives
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The solvent-free thermal dehydration of hexitols on zeolites
PublicationPodczas termicznej dehydratacji heksytoli w obecności zeolitów otrzymano szereg produktów zachodzących zarówno z inwersją lub retencją konfiguracji przy asymetrycznych atomach węgla. Produkty rozdzielano i identyfikowano przy pomocy chromatografii i spektroskopii NMR. 1,4:3,6-dianhydroiditol scharakteryzowano przy pomocy rentgenowskiej analizy strukturalnej.
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Rozwój technologii wytwarzania szerokopasmowych kabli telekomunikacyjnych
PublicationPrzedstawiono nowe konstrukcje kabli optoelektrokomunikacyjnych: kabel energetyczny z modułem światłowodowym i kable światłowodowe przeznaczone do instalacji w kanalizacji ściekowej. Omówiono metodykę badań i czujniki wpływające na niezawodność produkowanych kabli, w tym mechanizm kompleksowego zarządzania jakością TQM.
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Phytochemical composition and biological activities of differently pigmented cabbage (Brassica oleracea var. capitata) and cauliflower (Brassica oleracea var. botrytis) varieties
PublicationBACKGROUND:Brassica plants contain awide spectrumofbioactive components that are responsible for their health-promoting potential such as vitamins, polyphenols and glucosinolates. This study attempted to relate the composition of bioactive phytochemicals and chosen biological activities (antioxidant, cytotoxic, anti-genotoxic, and influence on enzymatic activities) for extracts from differently pigmented cabbage (white and red)...
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The comparison of betalain composition and chosen biological activities for differently pigmented prickly pear (Opuntia ficus-indica) and beetroot (Beta vulgaris) varieties
PublicationBetalains are a group of plant originated pigments with chemopreventive potential. The aim of this study was to relate the composition of betalains and chosen biological activities (antioxidant, cytotoxic, anti-genotoxic and influence on enzymatic activities) for extracts from differently pigmented varieties of prickly pear (yellow, orange and red) and beetroot (white and red). The assumption was that phytocomplexes of tested varieties...
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Piroxicam derivatives THz classification
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Recommendations for the prevention, diagnosis and treatment of inFLUenza in adults for Primary care physiciAnS: FLU COMPAS PCP – ADULTS
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Structural characterization and biological properties of a new dinuclear oxidovanadium(IV) N -(phosphonomethyl)iminodiacetate complex with the 4-amino-2-methylquinolinium cation
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Mechanism of Binding of Antifungal Antibiotic Amphotericin B to Lipid Membranes: An Insight from Combined Single-Membrane Imaging, Microspectroscopy, and Molecular Dynamics
PublicationAmphotericin B is a lifesaving polyene antibiotic used in the treatment of systemic mycoses. Unfortunately, the pharmacological applicability of this drug is limited because of its severe toxic side effects. At the same time, the lack of a well-defined mechanism of selectivity hampers the efforts to rationally design safer derivatives. As the drug primarily targets the biomembranes of both fungi and humans, new insights into the...
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Magnetic field microsensor based on GaAs MESFET
PublicationA novel concept of the drain separation design in a horizontally-split-drain GaAs MAGFET sensor, based on epitaxial layer growth, was developed. Proper choice of GaAs/AlAs/GaAs epitaxial layer sequence provided good electrical isolation between the drain regions. The measured leakage current between the drain regions was in the range of nA for up to 2V drain voltage bias difference. Performed analytical and numerical calculations...
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Methods of estimating the elements of water balance in a forested catchment basin
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New class of quaternary ammonium salts, derivatives of methyl D-glucopyranosides.
PublicationReakcja zasad azotowych z 6-O-p-tozylo-alfa-D-glukopiranozydem metylu lub 6-O-tozylo-beta-D-glukopiranozydem metylu (prowadzona w skali mikro) dając odpowiednie sole amoniowe. Jako zasady azotowe użyto pirydyny, 2-metylopirydyny i trimetyloaminy. Produkty zostały przebadane przy użyciu spektroskopii 1H, 13C NMR, spektroskopii mas oraz analizy elementarnej a budowa jednego z nich została dodatkowo potwierdzona za pomocą rentgenowskiej...
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Synthesis and structure of selected quaternary N-(1,4-anhydro-5-deoxy-2,3-O-isopropylidene-D,L-ribitol-5-yl)ammonium salts.
PublicationOpracowano metody otrzymywania czwartorzędowych soli amoniowych, pochodnych rybitolu, zawierających reszty: pirydyny, 2-metylopirydyny, 3-karbamoilopirydyny, 4-(N,N-dimetyloamino)pirydyny, chinoliny oraz dwóch amin alifatycznych trimetyloaminy i trietyloaminy. Związki te powstają w reakcji 1,4-anhydro-2,3-O-izopropylideno-5-O-tozylo-D,L-rybitolu z odpowiednimi zasadami azotowymi.
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Synthetic, Structural, and Spectroscopic Characterization of a Novel Family of High-Spin Iron(II) [(β-Diketiminate)(phosphanylphosphido)] Complexes
PublicationThis work describes a series of iron(II) phosphanylphosphido complexes. These compounds were obtained by reacting lithiated diphosphanes R2PP(SiMe3)Li (R = t-Bu, i-Pr) with an iron(II) β-diketiminate complex, [LFe(μ2-Cl)2Li(DME)2] (1), where DME = 1,2-dimethoxyethane and L = Dippnacnac (β-diketiminate). While the reaction of 1 with t-Bu2PP(SiMe3)Li yields [LFe(η1-Me3SiPPt- Bu2)] (2), that of 1 with equimolar amounts of i-Pr2PP(SiMe3)Li,...
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Characterization of antimicrobial and hemolytic properties of short synthetic cationic lipopeptides based on QSAR/QSTR approach
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Wavelet Analysis for Damage Identification in Composite Structures
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Rytuksymab – pierwsze biopodobne przeciwciała monoklonalne w hematoonkologii
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The Disturbances of Magnesium in Patients With Thromboembolic Complications After a Cholecystectomy
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Arterial stiffness, central hemodynamics and wave reflection in normal pregnancy and control nonpregnant women
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The photophysics of β-homo-tyrosine and its simple derivatives
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Influence of Leu5 configuration on the equilibrium constants of complexes of [Leu]-enkephalin with β-cyclodextrin studied by fluorescence spectroscopy, microcalorimetry and 1H NMR spectroscopy
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Recommendations of the Polish Psychiatric Association regarding the treatment of affective disorders in women of childbearing age. Part II: Bipolar disorder
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Highly Specific Substrates of Proteinase 3 Containing 3-(2-Benzoxazol-5-yl)-l-alanine and Their Application for Detection of This Enzyme in Human Serum
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Design of selective substrates of proteinase 3 using combinatorial chemistry methods
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The new fluorogenic substrates of neutrophil proteinase 3 optimized in prime site region
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Identification of acoustic event of selected noise sources in a long-term environmental monitoring systems
PublicationABSTRACT Undertaking long-term acoustic measurements on sites located near an airport is related to a problem of large quantities of recorded data, which very often represents information not related to flight operations. In such areas, usually defined as zone of limited use, often other sources of noise exist, such as roads or railway lines treated is such context as acoustic background. Manual verification of such recorded data...
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Increased Urinary C-Peptide and Albumin Excretion in Juvenile Borderline Hypertensives
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Expression of genes involved in neurogenesis, and neuronal precursor cell proliferation and development: Novel pathways of human ovarian granulosa cell differentiation and transdifferentiation capability in�vitro
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Weryfikacja stałoprądowego modelu tranzystora typu MAGFET
PublicationZaproponowano kompletny, stałoprĄdowy model tranzystora typu MAGFET wykorzystywanego jako czujnik pola magnetycznego. Zaprezentowany model odzwierciedla zależnoŚć podziału prĄdu płynącego w kanale tranzystora na prądy drenów od napięć drenów.
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Małosygnałowy model tranzystora typu MAGFET
PublicationWyprowadzono małosygnałowy model tranzystora typu MAGFET pracującego jako czujnik pola magnetycznego, w którym uwzględniono wzajemne oddziaływanie napięć drenów. Wykorzystując nowoopracowany model obliczono czułość napięciową typowego układu pracy MAGFET-a na pole magnetyczne.
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Effect of Converting Enzyme Inhibitor on Copper and Iron Concentrations of Blood Plasma in Calves During the Neonatal Period
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The Global Boundary Stratotype Section and Point (GSSP) for the base of the Coniacian Stage (Salzgitter-Salder, Germany) and its auxiliary sections (Słupia Nadbrzeżna, central Poland; Střeleč, Czech Republic; and El Rosario, NE Mexico)
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Anti-inflammatory Activity and Phytochemical Profile of Galinsoga Parviflora Cav.
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Novel markers of human ovarian granulosa cell differentiation toward osteoblast lineage: A microarray approach
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Recommendations of the Polish Psychiatric Association for treatment of affective disorders in women of childbearing age. Part III: Approach to pregnancy loss and unsuccessful in vitro treatment of infertility
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Effect of xanthophyll pigments on fluorescence of chlorophyll a in LHC II embedded to liposomes
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Synthetic genistein derivatives as modulators of glycosaminoglycan storage
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Strategia nauk technicznych do roku 2020 - propozycje
PublicationW pracy przedstawiono strategię proponowaną przez Wydział IV Nauk Technicznych PAN w perspektywie wieloletniej. Opisano założenia, cele strategiczne i uwarunkowania rozwoju nauk informacyjnych (informatyka, automatyka, robotyka, telekomunikacja) mikro- i nanotechnologii, optoelektroniki, bioinżynierii, systemów energetycznych i nowych źródeł energii.
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Nowe metody przetwarzania sygnałów w wybranych zagadnieniach wibroakustyki
PublicationMonografia Nowe Metody Przetwarzania Sygnałów w Wybranych Zagadnieniach Wibroakustyki będąca piętnastym Tomem z serii Monografie Katedry Automatyzacji Procesów AGH w Krakowie poświęcona jest zagadnieniom związanym z zastosowaniem i wykorzystaniem metod przetwarzania sygnałów wibroakustycznych w wybranych problemach technicznych i medycznych. W pierwszym rozdziale niniejszej monografii przedstawiono zagadnienia dotyczące metod przetwarzania...
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Are the short cationic lipopeptides bacterial membrane disruptors? Structure-Activity Relationship and molecular dynamic evaluation
PublicationShort cationic lipopeptides are amphiphilic molecules that exhibit antimicrobial activity mainly against Grampositives. These compounds bind to bacterial membranes and disrupt their integrity. Here we examine the structure-activity relation (SAR) of lysine-based lipopeptides, with a prospect to rationally design more active compounds. The presented study aims to explain how antimicrobial activity of lipopeptides is affected by...
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Activities of the Astro-geodetic Observatory in Jozefoslaw in the frame of IGS and EUREF
PublicationThe Astrogeodetic Observatory of the Institute of Geodesy and Geodetic Astronomy of the Warsaw University of Technology (WUT) in Jozefoslaw was incorporated in 1957. In 1991 it joined the International GPS Service (IGS) and started to operate as a permanent in 1993. Since then the following permanent services have been maintained: GPS observations using Trimble and Turbo Rogue receivers, tidal gravimetric observations with LaCoste&Romberg...
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Molecular organization of antifungal antibiotic amphotericin B in lipid monolayers studied by means of Fluorescence Lifetime Imaging Microscopy
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Mechanisms shaping the synergism of zeaxanthin and PsbS in photoprotective energy dissipation in the photosynthetic apparatus of plants
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Dihydroxy-Substituted Coumarins as Fluorescent Probes for Nanomolar-Level Detection of the 4-Amino-TEMPO Spin Label
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Human sperm proteins identified by 2-dimensional electrophoresis and mass spectrometry and their relevance to a transcriptomic analysis
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Promising effects of xanthine oxidase inhibition by allopurinol on autonomic heart regulation estimated by heart rate variability (HRV) analysis in rats exposed to hypoxia and hyperoxia
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Stałoprądowy model tranzystora typu HSD MAGFET
PublicationZaproponowano stałoprądowy model dwudrenowego tranzystora polowego typu HSD MAGFET, wykorzystywanego jako czujnik pola magnetycznego o dużej czułości na zmiany pola magnetycznego i dużej geometrycznej rozdzielczości pomiarowej. Zaprezentowany model odzwierciedla zjawisko podziału prądu płynącego w kanale tranzystora na prądy drenów i uwzględnia wzajemne oddziaływanie napięć drenów VDS1 i VDS2 na prady drenów ID1 i ID2 poprzez wprowadzenie...
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Luminescence properties of Eu3+ and Tb3+ doped silica-based xerogels
PublicationPure SiO2 xerogels and SiO2 xerogels containing SrF2: Eu3+/: Tb3+ crystals were prepared using sol-gel method. Luminescent spectra showed excitation and emission peaks characteristic to Eu3+ and Tb3+ 4f - 4f transitions. ET Tb3+→Eu3+ has been observed. XRD pattern of SiO2 matrix confirmed lack of long range order. Patterns of SiO2-SrF2:Eu3+ and SiO2-SrF2:Tb3+ showed peaks corresponding to SrF2. SEM images have shown agglomerates...
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Localization and Orientation of Xanthophylls in a Lipid Bilayer
PublicationXanthophylls (polar carotenoids) play diverse biological roles, among which are modulation of the physical properties of lipid membranes and protection of biomembranes against oxidative damage. Molecular mechanisms underlying these functions are intimately related to the localization and orientation of xanthophyll molecules in lipid membranes. In the present work, we address the problem of localization and orientation of two xanthophylls...