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Seasonality of Psoriasis: From Genes to the Clinical Phenomena
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Common variants of DNA repair genes and malignant melanoma
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Detection of sulfonamide resistance genes via in situ PCR-FISH
PublicationDue to the rising use of antibiotics and as a consequence of their concentration in the environment an increasing number of antibiotic resistant bacteria is observed. The phenomenon has a hazardous impact on human and animal life. Sulfamethoxazole is one of the sulfonamides commonly detected in surface waters and soil. The aim of the study was to detect sulfamethoxazole resistance genes in activated sludge biocenosis by use of...
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Common variants of xeroderma pigmentosum genes and prostate cancer risk
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Estrogen receptors genes polymorphisms and age at menarche in idiopathic scoliosis
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Association of Genes Related to Oxidative Stress with the Extent of Coronary Atherosclerosis
PublicationOxidative stress is believed to play a critical role in atherosclerosis initiation and progression. In line with this, in a group of 1099 subjects, we determined eight single nucleotide polymorphisms (SNPs) related to oxidative stress (PON1 c.575A>G, MPO c.463G>A, SOD2 c.47T>C, GCLM c.590C>T, NOS3 c.894G>T, NOS3 c.786T>C, CYBA c.214C>T, and CYBA c.932A>G) and assessed the extent of atherosclerosis in coronary arteries based on...
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The role of regulatory T cells and genes involved in their differentiation in pathogenesis of selected inflammatory and neoplastic skin diseases. Part III: Polymorphisms of genes involved in Tregs’ activation and function
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A universal method for the identification of genes encoding amatoxins and phallotoxins in poisonous mushrooms
PublicationABSTRACT Background. As the currently known diagnostic DNA targets amplified in the PCR assays for detection of poisonous mushrooms have their counterparts in edible species, there is a need to design PCR primers specific to the genes encoding amanitins and phallotoxins, which occur only in poisonous mushrooms. Objective. The aim of the study was testing of PCR-based method for detection of all genes encoding hepatotoxic cyclic...
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Influence of Escherichia coli on Expression of Selected Human Drug Addiction Genes
PublicationThe impact of enteric microflora on the expression of genes associated with cocaine and amphetamine addiction was described. Human genome-wide experiments on RNA transcripts expressed in response to three selected Escherichia coli strains allowed for significant alteration (p > 0.05) of the linear regression model between HT-29 RNA transcripts associated with the KEGG pathway:hsa05030:Cocaine addiction after 3 h stimulation with...
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Epigenetic regulation and regeneration: the search for differentially methylated genes in the MRL mouse
PublicationThe MRL mouse is an inbred laboratory strain, which was developed in the 60’s of the 20th century and has been extensively used as a model of lupus erythematosus. The regenerative abilities of the strain were discovered in the 90' when the MRL mouse was shown to close 2 mm hole punches made in the ear pinnae four weeks after injury without scarring. The phenomenon has not been observed in other mouse strains, where the holes...
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The Role of Dopaminergic Genes in Probabilistic Reinforcement Learning in Schizophrenia Spectrum Disorders
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Microarray analysis of differentially expressed genes in cells resistant to HIV-1
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Disruption of homocitrate synthase genes in Candida albicans affects growth but not virulence
PublicationDwa geny, LYS21 i LYS22, kodujące izoformy syntazy homocytrynianowej, enzymu katalizującego pierwszy wyjątkowy etap w szlaku biosyntezy lizyny, zostały rozbite z komórkach Candida albicans z wykorzystaniem strategii ''SAT flipper''. Podwójny mutant lys21delta/lys22delta nie wykazywał aktywności syntazy homocytrynianowej, natomiast charakteryzował się auksotrofią wzrostową wobec lizyny w podłożach minimalnych, co można było odwrócić...
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Genes of cellular components of morphogenesis in porcine oocytes before and after IVM
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Genes involved in glucocorticoid receptor signalling affect susceptibility to mood disorders
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Selected mitochondrial genes as species markers of the Arctic Contracaecum osculatum complex
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Amplification of the PDGFRA, KIT and KDR genes in glioblastoma: a population-based study
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Activities of genes controlling sphingolipid metabolism in human fibroblasts treated with flavonoids
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Modulation of expression of genes involved in glycosaminoglycan metabolism and lysosome biogenesis by flavonoids
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Defect in Mitochondrial NADH-Dehydrogenase Genes in Canine Mast Cell Tumours
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Direct cloning of heavy metal resistance genes from metagenomic DNA
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Transcriptional activity of epigenetic remodeling genes declines in keratinocytes after in vitro expansion
PublicationPURPOSE: In vitro expansion is an invaluable method to obtain keratinocytes in amounts necessary for effective transplantation therapies. In vitro cell culturing provokes questions concerning potential epigenetic alterations occurring in expanded cells in the context of usefulness for transplantation and safety. The purpose of this study was to investigate as to whether keratinocyte expansion is associated with changes in the activity...
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Significant Down-Regulation of “Biological Adhesion” Genes in Porcine Oocytes after IVM
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Genes regulating programmed cell death are significantly upregulated in porcine immature oocytes
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Altered circadian genes expression in breast cancer tissue according to the clinical characteristics
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Polymorphisms in nucleotide excision repair genes and susceptibility to colorectal cancer in the Polish population
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Erratum to: Activities of genes controlling sphingolipid metabolism in human fibroblasts treated with flavonoids
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The methylation of a panel of genes differentiates low-grade from high-grade gliomas
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Variances in the Expression Profile of Circadian Clock-Related Genes in Astrocytic Brain Tumors
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Selection of reliable reference genes in eutopic and ectopic endometrium for quantitative expression studies
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Differential Expression of HIF1A, EPAS1, and VEGF Genes in Benign and Malignant Ovarian Neoplasia
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Correlation between chosen polymorphisms in genes coding 5HTT, 5HT2A and COMT with obesity.
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Effects of traumatic life events, cognitive biases and variation in dopaminergic genes on psychosis proneness
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Immunological response of sheep to injections of plasmids encoding Toxoplasma gondii SAG1 and ROP1 genes
PublicationInfection with the intracellular protozoan parasite Toxo¬plasma gondii (T. gondii) causes health problems to both humans and livestock and has a large economic impact worldwide. The immune response in sheep following infection with T. gondii was evaluated using six different combinations of plasmid DNA, recombinant antigen and adjuvant. Sheep were generally vaccinated twice by intramuscular injection with plasmid DNA containing...
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Expression profiles and genomic organisation of group A protein phosphatase 2C genes inBrassica oleracea
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Association between Age at Diagnosis of Graves' Disease and Variants in Genes Involved in Immune Response
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Correction: Corrigendum: Modulation of expression of genes involved in glycosaminoglycan metabolism and lysosome biogenesis by flavonoids
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Correction: Corrigendum: Modulation of expression of genes involved in glycosaminoglycan metabolism and lysosome biogenesis by flavonoids
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Simultaneous siRNA-mediated silencing of pairs of genes coding for enzymes involved in glycosaminoglycan synthesis.
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Identification of Leaf Rust Resistance Genes in Selected Wheat Cultivars and Development of Multiplex PCR
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Removal of selected sulfonamides and sulfonamide resistance genes from wastewater in full-scale constructed wetlands
PublicationSulfonamides are high-consumption antibiotics that reach the aquatic environment. The threat related to their presence in wastewater and the environment is not only associated with their antibacterial properties, but also with risk of the spread of drug resistance in bacteria. Therefore, the aim of this work was to evaluate the occurrence of eight commonly used sulfonamides, sulfonamide resistance genes (sul1–3) and integrase genes...
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A role for accessory genes rI.-1 and rI.1 in the regulation of lysis inhibition by bacteriophage T4
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Hyponastic Leaves 1 Interacts with RNA Pol II to Ensure Proper Transcription of MicroRNA Genes
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A different methylation profile of circadian genes promoter in breast cancer patients according to clinicopathological features
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P.238 Lithium treatment modulates the expression of inflammation involved genes in major depressive disorder
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Increased Expression of Several Collagen Genes is Associated with Drug Resistance in Ovarian Cancer Cell Lines
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Expression Changes in Fatty acid Metabolic Processrelated Genes in Porcine Oocytes During in Vitro Maturation
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Haloperidol, but not olanzapine, may affect expression of PER1 and CRY1 genes in human glioblastoma cell line
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Coexistence of HFE and rare UGT1A1 genes mutations in patients with iron overload related liver injury
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Enterococci isolated from plant-derived food - Analysis of antibiotic resistance and the occurrence of resistance genes
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