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GUT Beyond Borders STE(E)R-ING towards International Doctoral School
ProjectsProject realized in Doctoral School according to PPI/STE/2020/1/00023/U/00001 agreement from 2020-12-11
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An integrated DNA and RNA variant detector identifies a highly conserved three base exon in the MAP4K5 kinase locus
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The effects of p53 gene inactivation on mutant proteome expression in a human melanoma cell model
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Anthrapyridones, a novel group of antitumour non-cross resistant anthraqui-none analogues. Synthesis and molecular basis of the cytotoxic activity towards K562/DOX cells
PublicationOpracowano syntezę nowej grupy związków z grupy antrapirydonów z odpowiednimi hydrofobowymi lub hydrofilowymi podstawnikami. Badano działanie tych związków na komórkach K562/S i K562/DOX (nadekspresja P-glikoproteiny). Stwierdzono, że zwiększenie lipofilowości zwiększa szybkość P-gp zależnego efluksu z komórki.
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On the formation process of silicon carbide nanophases via hydrogenated thermally induced templated synthesis
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Magnetic Silica Nanotubes: Synthesis, Drug Release, and Feasibility for Magnetic Hyperthermia
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MOLECULAR SIMULATIONS OF NEOCARZINOSTATIN CHROMOPHORE RELEASE MECHANISM
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Molecular simulations study of ligand-release mechanism in an odorant-binding protein from the southern house mosquito
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Filling of Carbon Nanotubes: Containers for Magnetic Probes and Drug Delivery
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The serum concentration of brain-derived neurotrophic factor is lower in ambulatory and clinically stable patients with more advanced systolic heart failure
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Human UDP-Glucuronosyltransferases: Effects of altered expression in breast and pancreatic cancer cell lines.
PublicationIncreased aerobic glycolysis and de novo lipid biosynthesis are common characteristics of invasive cancers. UDP-glucuronosyltransferases (UGTs) are phase II drug metabolizing enzymes that in normal cells possess the ability to glucuronidate these lipids and speed their excretion; however, de-regulation of these enzymes in cancer cells can lead to an accumulation of bioactive lipids, which further fuels cancer progression. We hypothesize...
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Projekt Architektoniczny II_ SEM 2 MGR 2020/21_Architektura połączeń i aktywizacji przestrzeni nadwodnych w Łebie
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Oświetlenie elektryczne [2019/20]
e-Learning CoursesKurs zawierający materiały do prowadzenia zajęć laboratoryjnych z przedmiotu "Oświetlenie elektryczne" - Energetyka, studia I stopnia - inżynierskie, stacjonarne, semestr 6
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Wearable Cardioverter–Defibrillator after Myocardial Infarction
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Analytical studies on ascosin, candicidin and levorin multicomponent antifungal antibiotic complexes. The stereostructure of ascosin A2
PublicationIn the class of polyene macrolides, there is a subgroup of aromatic heptaenes, which exhibit the highest antifungal activity within this type of antibiotics. Yet, due to their complex nature, aromatic heptaenes were not extensively studied and their potential as drugs is currently underexploited. Moreover, there are many inconsistencies in the literature regarding the composition and the structures of the individual components...
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Photosensitizing potential of tailored magnetite hybrid nanoparticles functionalized with levan and zinc (II) phthalocyanine
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Correction to: The chemistry and toxicity of discharge waters from copper mine tailing impoundment in the valley of the Apuseni Mountains in Romania
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The chemistry and toxicity of discharge waters from copper mine tailing impoundment in the valley of the Apuseni Mountains in Romania
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Optimising DNA binding to carbon nanotubes by non-covalent methods
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Assessment of Electronic Sensing Techniques for the Rapid Identification of Alveolar Echinococcosis through Exhaled Breath Analysis
PublicationHere we present a proof-of-concept study showing the potential of a chemical gas sensors system to identify the patients with alveolar echinococcosis disease through exhaled breath analysis. The sensors system employed comprised an array of three commercial gas sensors and a custom gas sensor based on WO3 nanowires doped with gold nanoparticles, optimized for the measurement of common breath volatile organic compounds. The measurement...
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Modification of SiC based nanorods via a hydrogenated annealing process
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Bulk synthesis of carbon-filled silicon carbide nanotubes with a narrow diameter distribution
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Anticancer Imidazoacridinone C-1311 is Effective in Androgen-Dependent and Androgen-Independent Prostate Cancer Cells
PublicationAndrogen receptor (AR) plays a crutial role in prostate cancer (PCa) development and metastasis. Here, we reported potent anti-PCa activity of a small molecule imidazoacridinone C-1311. In AR-positive PCa cells, C-1311 was found to inhibit the transcriptional activity of AR uncovering a novel mechanism that may be relevant for its anticancer effect. Mechanistically, C-1311 decreased AR binding to prostate-specific antigen (PSA)...
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Joint experimental and theoretical study on low-energy elastic electron scattering by gaseous alkynes: Differential cross sections, shape resonances, and methylation effects
PublicationA detailed comparison of experimental and theoretical elastic cross sections for low-energy electron scattering by ethyne, taken earlier in our group by Gauf et al. [Phys. Rev. A 87, 012710 (2013)], and some of its methylated derivatives, propyne, and the isomers 1-butyne and 2-butyne, taken here, are presented. The present differential cross sections were measured at incident electron energies ranging from 1 eV to 30 eV and...
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Chemometria i metodologia badań doświadczalnych
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Podstawy chemometrii - 22/23 - letni
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The chitosan – Porphyrazine hybrid materials and their photochemical properties
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The efficiency and technological reliability of biogenic compounds removal during long-term operation of a one-stage subsurface horizontal flow constructed wetland
PublicationThe paper presents the results of a study of the efficiency and technological reliability of total nitrogen and total phosphorus removal during long term operation of a one-stage constructed wetland system with subsurface horizontal wastewater flow. The flow rate of the wastewater treatment plant was 1.2m3/d during the research period. Physical and chemical analyses of raw wastewater and treated effluent were carried out in the...
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On the Formation of Single-Walled Carbon Nanotubes in Pulsed-Laser-Assisted Chemical Vapor Deposition
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Facilitating the CVD synthesis of seamless double-walled carbon nanotubes
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Elastic scattering of electrons from chloroform
PublicationWe present experimental and theoretical cross sections for elastic electron scattering from CHCl3. This is an important target because of its relevance to environmental chemistry and the plasma etching industry as a source of chlorine radicals. The experimental results were obtained at incident electron energies ranging from 0.5 to 800 eV in the 10deg-130deg scattering angle range. Theoretically, the scattering cross sections in...
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Gallic Acid-Functionalized, TiO2-Based Nanomaterial—Preparation, Physicochemical and Biological Properties
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Intramolecular transformation of an antifungal antibiotic nystatin A1 into its isomer, iso-nystatin A1 - structural and molecular modeling studies
PublicationNystatin A1, a polyene macrolide antifungal antibiotic, in a slightly basic or acidic solution undergoes an intramolecular transformation, yielding a structural isomer, the translactonization product, iso-nystatin A1 with lactone ring diminished by two carbon atoms. Structural evidence is provided by advanced NMR and Mass Spectrometry (MS) studies. Molecular dynamics simulations and quantum mechanics calculations gave the insight...
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Wpływ redukcji emisji CO2 na funkcjonowanie sektorów biopaliw transportowych w Polsce ze szczególnym uwzględnieniem sektora bioetanolu
PublicationW artykule omówione zostały zagadnienia dotyczące produkcji bioetanolu w Polsce, w aspekcie wymogów unijnych. Artykuł prezentuje ponadto modele badawczo-decyzyjne, na podstawie których zostały zrealizowane badania wśród przedsiębiorstw produkujących bioetanol oraz model zalecany na przyszłość. Do zaprezentowanych przykładów przedsiębiorstw produkcyjnych bioetanol 1. generacji należy odnieść się w kontekście zmian techniczno-technologicznych...
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Analysis of exhaled breath for dengue disease detection by low-cost electronic nose system
PublicationThis paper presents a procedure and a set-up of an electronic nose system analyzing exhaled breath to detect the patients suffering from dengue – a mosquito-borne tropical disease. Low-power resistive gas sensors (MiCS-6814, TGS8100) were used to detect volatile organic compounds (VOCs) in the exhaled breath. The end-tidal phase of patients exhaled breath was collected with a BioVOCTM breath sampler. Two strategies were assessed...
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A personalised approach to prostate cancer screening based on genotyping of risk founder alleles
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Comparison of different digestion methods for proteomic analysis of isolated cells and FFPE tissue samples
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Fabrication method of parallel mesoporous carbon nanotubes
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Enhancement of the structure stability of MOF‐5 confined to multiwalled carbon nanotubes
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Physico-chemical properties and possible photocatalytic applications of titanate nanotubes synthesized via hydrothermal method
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Effects triggered by platinum nanoparticles on primary keratinocytes
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Reduced diameter distribution of single-wall carbon nanotubes by selective oxidation
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Research - based technology education – the EDURES partnership experience
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Cation homeostasis and transport related gene markers are differentially expressed in porcine buccal pouch mucosal cells during long-term cells primary culture in vitro
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Synthesis, Growth Mechanism, and Electrochemical Properties of Hollow Mesoporous Carbon Spheres with Controlled Diameter
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Carbon‐Nanotube‐Based Stimuli‐Responsive Controlled‐Release System
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Synthesis, dispersion, and cytocompatibility of graphene oxide and reduced graphene oxide
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Synthesis, characterization, and photocatalytic properties of core/shell mesoporous silica nanospheres supporting nanocrystalline titania
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Wygodne siedzisko - krzesło do pracy i wypoczynku
InventionsPrzedmiotem wynalazku jest krzesło o cechach ergonomicznych, przeznaczone do szerokiego zastosowania użytkowego. Innowacyjność krzesła przejawia się w oryginalnym kształcie oraz formie dopasowanej ergonomicznie do siedzącej osoby. Krzesło posiada dwie odmiany: uwzględnia ramy sylwetki kobiety, uwzględnia ramy sylwetki mężczyzny.
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Methodology of generation of CFD meshes and 4D shape reconstruction of coronary arteries from patient-specific dynamic CT
PublicationDue to the difficulties in retrieving both the time‑dependent shapes of the vessels and the generation of numerical meshes for such cases, most of the simulations of blood flow in the cardiac arteries use static geometry. The article describes a methodology for generating a sequence of time‑dependent 3D shapes based on images of different resolutions and qualities acquired from ECG‑gated coronary artery CT angiography. The precision...