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Search results for: endocrine disrupting compounds
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Endocrine Disrupting Compounds – Problems and Challenges
PublicationIn this chapter, information about some of the estrogenic compounds and their environmental fate and biological influence can be found. Special attention is paid to the review of the analytical approaches used at the stages of detection and determination of Endocrine Disrupting Compounds (EDCs) in the environmental samples. Also, a brief characterization of both cellular and non-cellular bioassays is presented. The discovery of...
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Photochemical decomposition of endocrine disrupting compounds – A review
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Environmental fate of endocrine disrupting compounds - analytical problems and challenges
PublicationNarażenie na substancje wykazujące się aktywnością hormonów płciowych może negatywnie wpływać na układ endokrynny i rozrodczy u ludzi i innych organizmów żywych. Badania wykazały że obserwowane są znaczne wzrosty przypadków występowania nowotworów piersi, prostaty i jąder. Inne zaś wykazały obniżoną liczbę plemników w nasieniu mężczyzn i wydłużenie czasu oczekiwania na poczęcie. Odkrycia te znajdują potwierdzenie w badaniach polowych...
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Endocrine disrupting compounds in the baby's world - A harmful environment to the health of babies
PublicationGlobally, there has been a significant increase in awareness of the adverse effects of chemicals with known or suspected endocrine-acting properties on human health. Human exposure to endocrine disrupting compounds (EDCs) mainly occurs by ingestion and to some extent by inhalation and dermal uptake. Although it is difficult to assess the full impact of human exposure to EDCs, it is well known that timing of exposure is of importance...
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Development of a liquid chromatography–tandem mass spectrometryprocedure for determination of endocrine disrupting compounds infish from Mediterranean rivers
PublicationA new, sensitive and rapid method based on QuEChERS (Quick, Easy, Cheap, Effective, Rugged and Safe)approach followed by ultra high performance liquid chromatography coupled with tandem mass spec-trometry (UHPLC–MS/MS) was developed for the determination of nineteen endocrine disruptors (EDCs)and related compounds belonging to different classes in various fish species. Matrix effect on the analyti-cal performance was evaluated,...
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Evaluation of the Possibility of Using Hydroponic Cultivations for the Removal of Pharmaceuticals and Endocrine Disrupting Compounds in Municipal Sewage Treatment Plants
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Development of thin film SPME sorbents based on deep eutectic solvents and their application for isolation and preconcentration of endocrine-disrupting compounds leaching from diapers to urine
PublicationIn this study, the thin film solid phase microextraction (TF-SPME) based on a novel sorbent composed of deep eutectic solvent (DES) is proposed. Among several synthesized sorbents the most efficient was DES containing trihexyl(tetradecyl)phosphonium chloride and docosanol mixed with polydimethylsiloxane (PDMS) in a molar ratio 1:3:0.25 to achieve a more stable structure. The proposed sorbent was applied on a fiberglass mesh and...
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Deep eutectic solvents with solid supports used in microextraction processes applied for endocrine-disrupting chemicals
PublicationThe determination of endocrine-disrupting chemicals (EDCs) has become one of the biggest challenges in Analytical Chemistry. Due to the low concentration of these compounds in different kinds of samples, it becomes necessary to employ efficient sample preparation methods and sensitive measurement techniques to achieve low limits of detection. This issue becomes even more struggling when the principles of the Green Analytical Chemistry...
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Cold atmospheric pressure plasmas as versatile tools for effective degradation of a mixture of hazardous and endocrine disturbing compounds from liquid wastes
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Revision of Biological Methods for Determination of EDC Presence and Their Endocrine Potential
PublicationEndocrine-disrupting compounds (EDC) are chemicals responsible for disturbances in the hormonal balance of organisms. This group of chemicals includes both egzogenic and endogenic substances or their mixtures that impact functioning of natural hormones in organisms. In the available literature one can find information on the application of chromatographic and related techniques in the analysis of environmental samples for detection,...
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Assessment of cytotoxic and endocrine potential of selected xenobiotics commonly present in food products
PublicationMore and more increased intensity of anthropopressure processes can be observed, among other things, in the release of great quantities of synthetic substances into the environment, including the Endocrine Disrupting Compounds (EDC). A vast number of chemical substances is considered to belong to the this group, including substances which occur naturally in the environment, such as mycotoxins and phytoestrogens, and substances...
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Analytical aspects of model compounds toxicity assessment using MTT and Microtox bioanalytica assays
PublicationMore and more increased intensity of anthropopressure processes can be observed, among other things, in the release of great quantities of synthetic substances into the environment, including the Endocrine Disrupting Compounds. The effects of the above-mentioned human impact on the environment not only can be noticed in the homeostasis disturbance in ecosystems, but they are also visible with respect to human. The high incidence...
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Landfill leachates and wastewater of maritime origin as possible sources of endocrine disruptors in municipal wastewater
PublicationIn this study, wastewater from municipal services, such as a port wastewater reception facility (PRF-WW) and a municipal solid waste plant (MSWP), was tested for the presence of the suspected endocrine-disrupting compounds phthalates (PAEs) and bisphenol A (BPA). PAEs and BPA were found in this study in high concentrations in raw wastewater obtained from passenger ships (RMT-WWs) (up to 738 μg/L and 957 μg/L, respectively) collected...
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Factors determining accumulation of bisphenol A and alkylphenols at a low trophic level as exemplified by mussels Mytilus trossulus
PublicationThe aim of the study was to investigate abiotic and biotic factors influencing the accumulation of endocrine disrupting compounds (EDCs) such as bisphenol A (BPA), 4-tert-octylphenol (OP) and 4- nonylphenol (NP) in mussels Mytilus trossulus from the Gulf of Gdansk (Southern Baltic). The key abiotic factor influencing BPA, OP and NP accumulation in mussels is their hydrophilicity/lipophilicity, which affects their main assimilation...
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Bio-mitigation of organic pollutants using horseradish peroxidase as a promising biocatalytic platform for environmental sustainability
PublicationA wide array of environmental pollutants is often generated and released into the ecosystem from industrial and human activities. Antibiotics, phenolic compounds, hydroquinone, industrial dyes, and Endocrine-Disrupting Chemicals (EDCs) are prevalent pollutants in water matrices. To promote environmental sustainability and minimize the impact of these pollutants, it is essential to eliminate such contaminants. Although there are...
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Exposure scenario and risk assessment of infants and newborns to bisphenols and their derivatives from diapers
PublicationNewborns and infants are more sensitive to harmful compounds such as bisphenols and their derivatives because of their not fully developed detoxification mechanism. Exposure to these substances can lead to developmental problems and health consequences in adulthood. Since disposable baby diapers are used from the first days of life and remain in contact with the baby skin, it seems important to monitor the levels of endocrine disrupting chemicals...
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Związki endokrynne w środowisku: problemy i wyzwania
PublicationPoszczególne elementy środowiska od wielu lat było traktowane jako miejsce zrzutu substancji stanowiących odpady bądź też produkty uboczne procesów produkcyjnych i/lub dóbr konsumpcyjnych. Zanieczyszczenia rozpoznane przez naukowców podlegają regulacjom prawnym podającym dopuszczalne poziomy ich istnienia w środowisku. Istnieją jednak grupy związków o których istnieniu wiemy a których niebezpieczny charakter naukowcy zaczynają...
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Dziecięce pieluchy jednorazowe: walory konsumenckie a wpływ na zdrowie dziecka pod kątem zawartości związków endokrynnie czynnych
PublicationUkład hormonalny reguluje wiele procesów zachodzących w organizmie ludzkim. Jego funkcjonowanie może zostać zaburzone przez działanie związków z grupy endokrynnie czynnych (ang. Endocrine Disrupting Compounds, EDC) obecnych w otaczającym nas środowisku. Związki te mogą wpłynąć szkodliwie nie tylko na osobę eksponowaną na ich bezpośrednie działanie, ale również na jej potomstwo. Wyniki wieloletnich badań umożliwiły stwierdzenie,...
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Bisphenols and their derivatives in baby diaper samples.
PublicationMany common products contain and leach hazardous chemicals, including endocrine-disrupting chemicals such as bisphenols that are harmful to human health. For toddlers, this dangerousness is higher because of their not fully developed detoxification system. Due to this, bisphenols content in products such as baby diapers, should be monitored. Baby diapers not only remain in close contact with the skin, but are also used from the...
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Hormony płciowe w środowisku - zagrożenia jakie niosą ze sobą
PublicationSpośród dużej ilości i różnorodności związków chemicznych dostających się do środowiska coraz większą uwagę i szczególne zainteresowanie poświęca się związkom endokrynnym (ang. Endocrine Disrupting Coumpounds - EDCs). Wśród związków endokrynnych to estrogeny zarówno naturalne jak i syntetyczne zostały wskazane i opisane jako związki niosące ze sobą największy potencjał aktywności estrogennej. Jednym z głównych źródeł estrogenów...