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Search results for: KONJAC GLUCOMANNAN
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The Kinetics of FMS-Related Tyrosine Kinase 3 Ligand (Flt-3L) during Chemoradiotherapy Suggests a Potential Gain from the Earlier Initiation of Immunotherapy
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Efficient and Economically Favorable Co-Free Air Electrodes for Solid Oxide Cells
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Structure and oxygen permeability of BaCo0.7Fe0.3−In O3− ceramic membranes
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Synthesis and biological evaluation of fluorinated N-benzoyl and N-phenylacetoyl derivatives of 3-(4-aminophenyl)-coumarin-7-O-sulfamate as steroid sulfatase inhibitors
PublicationIn the present work, we report convenient methods for the synthesis of 3-(4-aminophenyl)-coumarin-7-O-sulfamate derivatives N-acylated with fluorinated analogues of benzoic or phenylacetic acid as steroid sulfatase (STS) inhibitors. The design of these potential STS inhibitors was supported by molecular modeling techniques. Additionally, computational docking methods were used to determine the binding modes of the synthesized inhibitors...
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Synthesis and biological evaluation of fluorinated 3-phenylcoumarin-7-O-sulfamate derivatives as steroid sulfatase inhibitors
PublicationIn the present work, we report the initial results of our study on a series of 3-phenylcoumarin sulfamate-based compounds containing C-F bonds as a novel inhibitors of steroid sulfatase (STS). The new compounds are potent STS inhibitors, possessing more than 10 times higher inhibitory potency than coumarin-7-O-sulfamate. In the course of our investigation, compounds 2b and 2c demonstrated the highest inhibitory effect in the enzymatic...
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Smooth least absolute deviation estimators for outlier-proof identification
PublicationThe paper proposes to identify the parameters of linear dynamic models based on the original implementation of least absolute deviation estimators. It is known that the object estimation procedures synthesized in the sense of the least sum of absolute prediction errors are particularly resistant to occasional outliers and gaps in the analyzed system data series, while the classical least squares procedure unfortunately becomes...
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System do diagnostyki dermatofitowych zakażeń powierzchniowych oparty na technice Real-Time PCR
PublicationDermatofity należą do blisko spokrewnionej grupy grzybów, które wykazują wysokie powinowactwo do skeratynizowanych tkanek. Cecha ta czyni je odpowiedzialnymi za powierzchniowe grzybice skóry, paznokci oraz włosów. Szacuje się, iż nawet do 20% ludzi na całym świecie dotkniętych jest infekcjami powodowanymi przez dermatofity. Ich leczenie wymaga długotrwałego zastosowania leków przeciwgrzybiczych. W celu dobrania odpowiedniego leczenia...
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Wpływ osmolitów na stabilność białek w oparciu o metodę dynamiki molekularnej
PublicationCelem niniejszej pracy było zbadanie molekularnego mechanizmu wpływu biologicznie znaczących związków, tzw. osmolitów na stabilność białek. Aby zweryfikować istniejące hipotezy i dostarczyć spójnego obrazu działania osmolitów na poziomie molekularnym, wykorzystano metodę dynamiki molekularnej do zasymulowania mechanicznej denaturacji modelowych białek – lizozymu i ubikwityny. W tym podejściu odtworzony został efekt stabilizujący...
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Materiały biozgodne i specjalnego przeznaczenia - laboratorium 2022-2023
e-Learning CoursesPrzedmiot dedykowany studentom VI sem. Inżynierii Biomedycznej (specjalność: Chemia w medycynie).
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2023/2024 - Architektury Usług Internetowych
e-Learning Coursesstudia inżynierskie, kierunek Informatyka oraz Inżynieria Danych
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Spotkanie informacyjne dla kandydatów do Szkoły Doktorskiej
EventsW dniu 29 czerwca, o godz. 11:00 (UTC+2) , odbędzie się spotkanie informacyjne dla kandydatów, dotyczące rekrutacji do Szkoły Doktorskiej PG na r.a. 2021/2022. Dostęp na hasło: PhD
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LDRAW based renders of LEGO bricks moving on a conveyor belt with extracted models
Open Research DataThe set contains renders of LEGO bricks moving on a white conveyor belt. The images were prepared for training neural network for recognition of LEGO bricks. For each brick starting position, alignment and color was selected (simulating the brick falling down on the conveyour belt) and than 10 images was created while the brick was moved across the...
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Previous Opinions is All You Need - Legal Information Retrieval System
PublicationWe present a system for retrieving the most relevant legal opinions to a given legal case or question. To this end, we checked several state-of-the-art neural language models. As a training and testing data, we use tens of thousands of legal cases as question-opinion pairs. Text data has been subjected to advanced pre-processing adapted to the specifics of the legal domain. We empirically chose the BERT-based HerBERT model to perform...
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The Characterization of Scaffolds Based on Dialdehyde Chitosan/Hyaluronic Acid
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Influence of hydrochloric acid concentration and type of nitrogen source on the electrochemical performance of TiO2/N-MoS2 for energy storage applications
PublicationIn this work, nitrogen-doped molybdenum sulfide was directly deposited on titanium dioxide nanotubes substrate (TiO2/N-MoS2) during hydrothermal synthesis. The study focuses on the influence of hydrochloric acid concentration used for the synthesis, with the results indicating its essential role in thioacetamide hydrolysis and thus in the effectiveness of the N-MoS2 deposition. The electrode material itself is characterized by...
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Diatoms Biomass as a Joint Source of Biosilica and Carbon for Lithium-Ion Battery Anodes
PublicationThe biomass of one type cultivated diatoms (Pseudostaurosira trainorii), being a source of 3D-stuctured biosilica and organic matter—the source of carbon, was thermally processed to become an electroactive material in a potential range adequate to become an anode in lithium ion batteries. Carbonized material was characterized by means of selected solid-state physics techniques (XRD, Raman, TGA). It was shown that the pyrolysis...
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CO2 Adsorption Study of Potassium-Based Activation of Carbon Spheres
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The New Elastomeric Compounds Made of Butyl Rubber Filled with Phyllosilicates, Characterized by Increased Barrier Properties and Hydrophobicity and Reduced Chemical Degradation
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Chemistry - Energy Technologies 2022/2023
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Chemia i Technologia Farmaceutyków - wykład
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Laboratorium z Chemii dla Fizyki Technicznej
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Przyjmowanie aplikacji do Szkoły Doktorskiej
EventsW dn. 5–10.09.2024 do godz. 11.00, Szkoła Doktorska będzie przyjmować aplikacje kandydatów wraz z kompletem dokumentów. Aplikacje należy składać elektronicznie w systemie rekrutacyjnym.
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Synthesis and properties of AxV2Al20 (A = Th, U, Np, Pu) ternary actinide aluminides
PublicationPolycrystalline samples of AxV2Al20 (A = Ce, Th, U, Np, Pu; 0.7 ≤ x ≤ 1.0) actinide intermetallics were synthesized using the arc-melting method. Crystal structure studies were performed by means of powder x-ray diffraction and the Rietveld refinement method. All studied compounds crystallize in the CeCr2Al20-type structure (space group Fd-3m, no. 227) with the actinoid and Ce atom located in the oversized icosahedral cage formed...
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Short clinically-based prediction model to forecast transition to psychosis in individuals at clinical high risk state
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MicroRNA profiling in a case-control study of African American women with uterine serous carcinoma
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Expression-based decision tree model reveals distinct microRNA expression pattern in pediatric neuronal and mixed neuronal-glial tumors
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The impact of resistance exercise range of motion on the magnitude of upper-body post-activation performance enhancement
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Co-free triple perovskite La1.5Ba1.5Cu3O7±δ as a promising air electrode material for solid oxide fuel cells
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Research on and Assessment of the Reliability of Railway Transport Systems with Induction Motors
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Influence of the Multiple Injection Moulding and Composting Time on the Properties of Selected Packaging and Furan-Based Polyesters
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Glycerol extracts of Glycyrrhiza glabra, Echinacea purpurea, Silybum marianum and Berberis vulgaris: chemical characterisation and cosmeceutical potential
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Changes in the Microrna Expression Profile in Patients Undergoing Autologous Steam Cell Transplantation
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Clinical significance of CD34, podoplanin and Ki-67 expression in patients with locally advanced squamous cell cervical carcinoma
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Validation of the Elderly Traumatic Brain Injury Score: Observational Case Control Study
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Effective calcium doping at the B-site of BaFeO3−δ perovskite: towards low-cost and high-performance oxygen permeation membranes
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High Cu content LaNi1-xCuxO3-δ perovskites as candidate air electrode materials for Reversible Solid Oxide Cells
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Modification of Ruddlesden-Popper-type Nd2-xNi0.75Cu0.2M0.05O4±δ by the Nd-site cationic deficiency and doping with Sc, Ga or In: Crystal structure, oxygen content, transport properties and oxygen permeability
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Investigation of In-doped BaFeO3−δ perovskite-type oxygen permeable membranes
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Titania nanotubes modified by a pyrolyzed metal-organic framework with zero valent iron centers as a photoanode with enhanced photoelectrochemical, photocatalytical activity and high capacitance
PublicationThe paper discusses the synthesis, photoelectrochemical and electrochemical behaviour of titania nanotube arrays modified by a pyrolyzed metal-organic framework (MOF). A poly(3,4–ethylenedioxyphene) (PEDOT) matrix with an embedded inorganic network of iron hexacyanoferrate (BP) covering TiO2 nanotubes (TNT) is used as a MOF for the further sintering procedure, resulting in a novel, thin film of carbonaceous wrap supported Fe catalytic...
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Synthesis and steroid sulfatase inhibitory activities of N-alkanoyl tyramine phosphates and thiophosphates
PublicationA series of phosphate and thiophosphate analogs based on the frameworks of N-alkanoyl tyramines have been synthesized and biologically evaluated. Their binding modes have been modeled using docking techniques. The inhibitory effects of the synthesized compounds were tested on STS isolated from the human placenta as well as the MCF-7, MDA-MB-231 and SkBr3 cancer cell lines. Most of the new STS inhibitors possessed potent activity...
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"Debata podatkowa" nt. zmian podatkowych w roku 2019
EventsPierwsze spotkanie z cyklu „Debat podatkowych” na WZiE, podczas którego zostaną omówione praktyczne aspekty związane ze zmianami podatkowymi w roku 2019, m.in: split payment, niższy CIT, exit tax i ulga na B+R.
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Konferencja „Lustro mediów IV – od chat botów do CX i UX”
Events4 grudnia w Centrum Kompetencji STOS odbędzie się konferencja z cyklu „Lustro mediów”.
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Konrad Czubak
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Konrad Buzak
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Konrad Kowalski
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Konrad Mrówka
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Konrad Wyszomierski
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Konrad Reiter
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Konrad Stolarczyk
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Konrad Sobota
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