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total: 784
Search results for: WYBOCZENIE GIETNE
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The Effect of Posaconazole, Itraconazole and Voriconazole in the Culture Medium on Aspergillus fumigatus Triazole Resistance
PublicationTriazoles are the only compounds used as antibiotics in both medicine and agriculture. The presence of triazoles in the environment can contribute to the acquisition of azole resistance among isolates of Aspergillus fumigatus. The objective of this study was to investigate the effect of A. fumigatus exposure to triazoles on susceptibility to these compounds. Seventeen triazole-resistant and 21 triazole-sensitive A. fumigatus isolates...
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Pathogenesis of psoriasis in the “omic” era. Part II. Genetic, genomic and epigenetic changes in psoriasis
PublicationPsoriasis is a multifactorial disease in which genetic, environmental and epigenetic factors regulating gene expression play a key role. In the “genomic era”, genome-wide association studies together with target genotyping platforms performed in different ethnic populations have found more than 50 genetic susceptible markers associated with the risk of psoriasis which have been identified so far. Up till now, the strongest association...
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Flavoenzyme-catalyzed redox cycling of hydroxylamino- and amino metabolites of 2,4,6-trinitrotoluene: implications for their cytotoxicity
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Evolution of chemotaxis in single-cell artificial organisms
PublicationThe model of a liquid two-dimensional environment, which is based on physics of diffusion, allows us to simulate the diffusion of morphogenes. Artificial organisms move using a chemotaxis reacting to concentration difference. Organisms are controlled by a gene regulatory network coded in a linear genome and reproduce by division. We made a lot of experiments presenting organisms’ behaviour in various environment conditions. We...
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Modelowanie konstrukcji mostowych - obliczenia i weryfikacja ''in situ''
PublicationObiekty mostowe są konstrukcjami inżynierskimi, które ze względu na ich odpowiedzialność i długi okres eksploatacji - przed oddaniem do użytkowania poddawane są wszechstronnej ocenie w formie badań, zwanych potocznie próbnym obciążeniem. Zadaniem tych badań jest sprawdzenie poprawności pracy konstrukcji i przyjętych założeń projektowych. Przyciągające uwagę społeczeństwa próbne obciążenie na moście poprzedza projekt jego badań....
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EASY ACCESS TOOL FOR SMALL INTERFERING RNA (siRNA) DATA
PublicationFor many decades it was an accepted dogma of molecular genetics that the expression of genes is a “one-way-road” leading only in one direction from DNA to RNA to proteins. Recent discoveries in modern molecular genetics have challenged this dogma showing that specific RNA molecules play a central role in controlling the activity of genes by changing the structure of DNA sequences, targeting other RNAs for degradation or blocking...
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Homoisocitrate dehydrogenase from Candida albicans: properties, inhibition, and targeting by an antifungal pro-drug
PublicationThe LYS12 gene from Candida albicans, coding for homoisocitrate dehydrogenase was cloned and expressed as a His-tagged protein in Escherichia coli. The purified gene product catalyzes the Mg2+- and K+-dependent oxidative decarboxylation of homoisocitrate to alpha-ketoadipate. The recombinant enzyme demonstrates strict specificity for homoisocitrate. SDS-PAGE of CaHIcDH revealed its molecular mass of 42.6±1 kDa, while in size-exclusion...
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Glomerular disorders in diseases classified elsewhere - Male, 71 - Tissue image [12030630017646721]
Open Research DataThis is the histopathological image of KIDNEY tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.
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Glomerular disorders in diseases classified elsewhere - Male, 71 - Tissue image [12030630017641981]
Open Research DataThis is the histopathological image of KIDNEY tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.
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Wytrzymałość materialów, W, MTR, Ist, sem. 03, zima, 2023/24, (PG_00055417)
e-Learning CoursesPodstawowe pojęcia wytrzymałości materiałów: Modelowanie. Współczynnik bezpieczeństwa. Momenty bezwładności figur płaskich. Ściskanie i rozciąganie prętów: Warunki równowagi i warunki geometryczne. Próba rozciągania i ściskania. Prawo Hookea. Moduł Younga. Liczba Poissona. Zagadnienia statycznie niewyznaczalne. Skręcanie prętów. Zginanie belek: Momenty gnące i siły poprzeczne. Czyste zginanie. Odkształcenia i naprężenia w belkach....
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Untangling the Evolutionary History of European Bison (Bison bonasus)
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Szablon kursu
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Praktyka kierunkowa (hydrauliczno-hydrochemiczna) 2023/2024
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Regulation of the First Committed Step in Lipopolysaccharide Biosynthesis Catalyzed by LpxC Requires the Essential Protein LapC (YejM) and HslVU Protease
PublicationWe previously showed that lipopolysaccharide (LPS) assembly requires the essential LapB protein to regulate FtsH-mediated proteolysis of LpxC protein that catalyzes the first committed step in the LPS synthesis. To further understand the essential function of LapB and its role in LpxC turnover, multicopy suppressors of ΔlapB revealed that overproduction of HslV protease subunit prevents its lethality by proteolytic degradation...
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Anticancer Imidazoacridinone C-1311 is Effective in Androgen-Dependent and Androgen-Independent Prostate Cancer Cells
PublicationAndrogen receptor (AR) plays a crutial role in prostate cancer (PCa) development and metastasis. Here, we reported potent anti-PCa activity of a small molecule imidazoacridinone C-1311. In AR-positive PCa cells, C-1311 was found to inhibit the transcriptional activity of AR uncovering a novel mechanism that may be relevant for its anticancer effect. Mechanistically, C-1311 decreased AR binding to prostate-specific antigen (PSA)...
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Linezolid-resistant Enterococcus faecium strains isolated from one hospital in Poland –commensals or hospital-adapted pathogens?
PublicationOne of the most pressing problems of enterococci infections is occurring resistance to linezolid, which is an antibiotic used in the treatment of infections caused by vancomycin-resistant strains (VRE). The main objective of our research was to investigate the relationship of 19 linezolid-resistant E. faecium isolates from 18 patients hospitalized at Clinical Hospital in Gdansk (Poland). One of the LZDREF was isolated in 2003...
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Synovial sarcoma, NOS - Male, 31 - Tissue image [6260730021885911]
Open Research DataThis is the histopathological image of OTHER AND ILL-DEFINED SITES tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.
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Synovial sarcoma, NOS - Female, 28 - Tissue image [6190730017322111]
Open Research DataThis is the histopathological image of KIDNEY tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.
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Mucinous carcinoma - Female, 73 - Tissue image [3150630013121201]
Open Research DataThis is the histopathological image of BREAST tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.
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Mucinous carcinoma - Female, 73 - Tissue image [3150630013128701]
Open Research DataThis is the histopathological image of BREAST tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.
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Synovial sarcoma, NOS - Female, 28 - Tissue image [619073001732951]
Open Research DataThis is the histopathological image of KIDNEY tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.
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Synovial sarcoma, NOS - Female, 28 - Tissue image [6190730017323261]
Open Research DataThis is the histopathological image of KIDNEY tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.
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Synovial sarcoma, NOS - Female, 28 - Tissue image [6190730017325791]
Open Research DataThis is the histopathological image of KIDNEY tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.
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Mucinous carcinoma - Female, 73 - Tissue image [3150630013121491]
Open Research DataThis is the histopathological image of BREAST tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.
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Mucinous carcinoma - Female, 73 - Tissue image [315063001312661]
Open Research DataThis is the histopathological image of BREAST tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.
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Synovial sarcoma, NOS - Male, 31 - Tissue image [6260730021884611]
Open Research DataThis is the histopathological image of OTHER AND ILL-DEFINED SITES tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.
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Synovial sarcoma, NOS - Male, 31 - Tissue image [6260730021881411]
Open Research DataThis is the histopathological image of OTHER AND ILL-DEFINED SITES tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.
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Synovial sarcoma, NOS - Female, 28 - Tissue image [619073001732131]
Open Research DataThis is the histopathological image of KIDNEY tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.
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Synovial sarcoma, NOS - Male, 31 - Tissue image [6260730021883731]
Open Research DataThis is the histopathological image of OTHER AND ILL-DEFINED SITES tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.
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Mucinous carcinoma - Female, 73 - Tissue image [3300730069471511]
Open Research DataThis is the histopathological image of BREAST tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.
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Synovial sarcoma, NOS - Female, 28 - Tissue image [6190730017326201]
Open Research DataThis is the histopathological image of KIDNEY tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.
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Synovial sarcoma, NOS - Male, 31 - Tissue image [6260730021885681]
Open Research DataThis is the histopathological image of OTHER AND ILL-DEFINED SITES tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.
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Synovial sarcoma, NOS - Female, 28 - Tissue image [6190730017323141]
Open Research DataThis is the histopathological image of KIDNEY tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.
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Synovial sarcoma, NOS - Female, 28 - Tissue image [6190730017325861]
Open Research DataThis is the histopathological image of KIDNEY tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.
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Edwards' syndrome, unspecified - Male, 1 - Tissue image [3070630010187471]
Open Research DataThis is the histopathological image of BRONCHUS AND LUNG tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.
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Other specified diseases of liver - Male, 11 - Tissue image [121606300126351]
Open Research DataThis is the histopathological image of LIVER AND INTRAHEPATIC BILE DUCTS tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.
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Other specified diseases of liver - Male, 11 - Tissue image [12160630012634401]
Open Research DataThis is the histopathological image of LIVER AND INTRAHEPATIC BILE DUCTS tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.
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Shock, unspecified - Male, 1 - Tissue image [3300730069429211]
Open Research DataThis is the histopathological image of BRAIN tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.
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Shock, unspecified - Male, 1 - Tissue image [3300730069424231]
Open Research DataThis is the histopathological image of BRAIN tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.
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Shock, unspecified - Male, 1 - Tissue image [3300730069428681]
Open Research DataThis is the histopathological image of BRAIN tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.
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Edwards' syndrome, unspecified - Male, 1 - Tissue image [3070630010188371]
Open Research DataThis is the histopathological image of BRONCHUS AND LUNG tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.
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Edwards' syndrome, unspecified - Male, 1 - Tissue image [3070630010185311]
Open Research DataThis is the histopathological image of BRONCHUS AND LUNG tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.
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Shock, unspecified - Male, 1 - Tissue image [3300730069414931]
Open Research DataThis is the histopathological image of BRAIN tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.
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Shock, unspecified - Male, 1 - Tissue image [3300730069426331]
Open Research DataThis is the histopathological image of BRAIN tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.
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Shock, unspecified - Male, 1 - Tissue image [3301001549103491]
Open Research DataThis is the histopathological image of BRAIN tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.
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Edwards' syndrome, unspecified - Male, 1 - Tissue image [3070630010182101]
Open Research DataThis is the histopathological image of BRONCHUS AND LUNG tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.
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Other specified diseases of liver - Male, 11 - Tissue image [12160630012636341]
Open Research DataThis is the histopathological image of LIVER AND INTRAHEPATIC BILE DUCTS tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.
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Longitudinal study of vitamins A, E and lipid oxidative damage in human milk throughout lactation
PublicationCelem pracy było zbadanie zmian wartości całkowitego potencjału antyoksydacyjnego (TAS), stężeń witamin antyoksydacyjnych i izoprostanów (markery stresu oksydacyjnego) w siarze i mleku dojrzałym. Badaniami objęto 49 kobiet po pełno terminowej ciąży i naturalnym porodzie. Kryteria wyłączenia to czynne i bierne palenie tytoniu, ostre i przewlekłe schorzeniach oraz farmakoterapia inna niż suplementacja witamin. Próbki siary pobierano...
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Assessment of the devulcanization process of EPDM waste from roofing systems by combined thermomechanical/microwave procedures
PublicationEthylene-propylene-diene rubber (EPDM) is a elastomer widely used in common industrial applications. EPDM can be shaped into sheets and employed as isolating material for roofing systems. In this study, scraps of EPDM from commercial, industrial and residential roofing systems were treated by combined thermo-mechanical and microwave devulcanization processes including peroxide of benzoyl (BPO). The devulcanized EPDM (Dev-EPDM)...
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Ewa Wawoczna, WCH, TCH+ITNE, II st, 2 sem, 20/21z
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