Search results for: PAWLAK’S FOWGRAPHS
-
The structure of levorin A3, a minor component of levorin complex
PublicationBudowa chemiczna składnika kompleksu leworyn, leworyny A3, została ustalona na podstawie analizy z wykorzystaniem metod spektroskopowych UV, MS i NMR metoksykarbonylometyloamido pochodnej leworyny A3. Widmo UV wskazało obecność chromoforu heptaenowego. Ciężar cząsteczkowy leworyny A3 ustalono jako 1110 j.m. za pomocą spektrometrii masowej z wykorzystaniem techniki FAB, co po uwzględnieniu uwarunkowań biogenetycznych pozwoliło wydedukować...
-
Synthesis and biological activity of novel ester derivatives of N3-(4-metoxyfumaroyl)-(S)-2,3-diaminopropanoic acid containing amide and keto function as inhibitors of glucosamine-6-phosphate synthase
PublicationA short series of novel ester derivatives of N3-4-methoxyfumaroyl-(S)-2,3-diaminopropanoic acid (FMDP) containing amido or keto functions have been designed and synthesized. Their antifungal activity and inhibitory properties toward fungal glucosamine-6-phosphate synthase has also been evaluated. The obtained compounds 11-13 and 15-17 demonstrated good antifunga activity against Candida albicans. Compounds 11-13 displayed also...
-
SONATA 13 Sea-snow POPs: the secondary cycle of persistent organic pollutants in the Arctic
ProjectsProject realized in Department of Analytical Chemistry according to UMO-2017/26/D/ST10/00630 agreement from 2018-10-01
-
Summer Course 2024 J. Pawlak-Mikuć
e-Learning Courses -
Unique canal communicating between both maxillary sinuses through the palatine recess with hypertrophy of sinuses
Publication -
Ten years of observations and demographics of hemimandibular hyperplasia and elongation
Publication -
Decreasing Vaccination Coverage Against Hepatitis B and Tuberculosis in Newborns
Publication -
A novel cold-active β-D-galactosidase with transglycosylation activity from the Antarctic Arthrobacter sp. 32cB - gene cloning, purification and characterization
PublicationA gene encoding a novel β-D-galactosidase from the psychrotolerant Antarctic bacterium Arthrobacter sp. 32cB was isolated, cloned and expressed in Escherichia coli. The active form of recombinant β-D-galactosidase consists of two subunits with a combined molecular weight of approximately 257 kDa. The enzyme's maximum activity towards o-nitrophenyl-β-D-galactopyranoside was determined as occurring at 28 °C and pH 8.0. However, it...
-
B-GALACTOSIDASE ARTHROBACTER SP. 32cB - OBTAINING THE GENE SEQUENCE, CONSTRUCTION OF THE EXPRESSION SYSTEM, BIOSYNTHESIS AND BIOCHEMICAL CHARACTERIZATION OF THE ENZYME
PublicationINTRODUCTION: β-Galactosidase is an enzyme which catalyzes the hydrolysis of O glycosidic bond in β-galactosides. Another activity of β galactosidase is a transglycosylation activity. The main industrial use of this protein is the hydrolysis of lactose in milk in a cooling conditions. Synthesis of galactooligosaccharides, which are mostly used as a prebiotics added to some foods or available as dietary supplements, is only one...
-
Elżbieta Cecerska-Heryć dr n.med.
PeopleWykształcenie i stopnie naukowe: 19.06.2018 r.ukończenie studiów doktoranckich z wyróżnieniem summa cum laudena Wydziale Lekarskim z OdziałemNauczania w Języku Angielskim PUM SzczecinStopień naukowy: doktor nauk medycznychWyższe2008-2013 Pomorski Uniwersytet Medyczny w Szczecinie Kierunek: Biotechnologia Specjalność: Biotechnologia MedycznaStudia licencjackie i magisterskieZatrudnienie...
-
J. Pawlak-Mikuć6,ZIE Ist, sem3,2022/2023z
e-Learning Courses -
Surface-Step-Induced Magnetic Anisotropy in Epitaxial LSMO Deposited on Engineered STO Surfaces
Publication -
Characterization of structure and properties of polymer films made from blends of polyethylene with poly(4-methyl-1-pentene)
Publication -
Band misplacement: a rare complication of laparoscopic adjustable gastric banding
Publication -
Room‐Temperature Multiferroicity and Magnetization Dynamics in Fe/BTO/LSMO Tunnel Junction
Publication -
Seasonal and spatial differences in metal and metalloid concentrations in the snow cover of Hansbreen, Svalbard
PublicationMetals and metalloids in snow on glaciers, depending on the season of deposition, may come from various sources: local rock dust (erosion of the geological substratum), marine aerosol, local human activity (e.g. fuel combustion, waste incineration) and long-range atmospheric transport. Hansbreen glacier, located close to the Polish Polar Station in Svalbard, is a perfect site to study metals and metalloids: it has complex geological...
-
Spatial Differences in the Chemical Composition of Surface Water in the Hornsund Fjord Area: A Statistical Analysis with A Focus on Local Pollution Sources
PublicationSurface catchments in Svalbard are sensitive to external pollution, and yet what is frequently considered external contamination may originate from local sources and natural processes. In this work, we analyze the chemical composition of surface waters in the catchments surrounding the Polish Polar Station in Svalbard, Hornsund fjord area. We have pooled unpublished and already published data describing surface water composition...
-
Monosaccharides as internal probes for the determination of the absolute configuration of 2-butanol
PublicationD-dlukoza, D-mannoza i L-ramnoza zostały poddane reakcji z mieszaniną racemiczną 2-butanolu. Otrzymane w ten sposób glikozydy były analizowane za pomocą spektroskopii NMR, z wykorzystaniem eksperymentów COSY i NOESY. Analiza konformacyjna wiązania glikozydowego (dokonana w oparciu o modelowanie molekularne i heteronuklearne stałe sprzężenia) wraz z analizą sprzężeń dipolowych obserwowanych w widmie NOESY umożliwiła określenie konfiguracji...
-
Technical and economic analysis of energy storage in the compressed air technology with low capacity for the production plant
PublicationCompressed air energy storage (CAES) system is a promising technology due to its numerous advantages, including relatively low maintenance cost, a long lifespan and high operational flexibility. This article explores the possibility of designing a CAES power plant as a source of electricity and heat for an existing industrial plant. The study involves the technical analysis of the power plant parameters and the economic analysis...
-
Joanna Pawlak-Mikuć mgr
People -
J. Pawlak-Mikuć 3 OiOIIst, sem1, 23/24L
e-Learning Courses -
The influence of 9-day trekking in the Alps on the level of oxidative stress parameters and blood parameters in native lowlanders
Publication -
Technical aspects of nasal cavity surgery through the Le Fort I down-fracture approach: An otolaryngologist’s point of view based on 90 patients’ experience
Publication -
The stereostructure of candicidin D.
PublicationThe candicidin D stereostructure was established based on NMR studies including DQF-COSY, ROESY, HSQC and HMBC experiments. The relative configurations of the candicidin D stereogenic centers were assigned as the following: 9R*, 11S*, 13S*, 15R*, 17S*, 18R*, 19S*, 21R*, 36S*, 37R*, 38S*, 40S* and 41S*. The geometry of the heptaene chromophore was defined as 22E, 24E, 26Z, 28Z, 30E, 32E and 34E.
-
The structure, including stereochemistry, of levorin A1
PublicationThe constitution and stereostructure of levorin A1 1, an aromatic heptaeneantifungal antibiotic, was established on the basis of NMR studies, which contained DQFCOSY,ROESY, HSQC and HMBC experiments. Mycosamine moiety was used as an internalchiral probe to determine the absolute configuration of levorin A1 stereogenic centers: 13S,15R, 17S, 18R, 19S, 21R. The relative configuration of the remaining stereogenic centers wasassigned...
-
Właściwości katalityczne i biomedyczne związków zawierających jony rutenu(II) oraz rutenu(III)
PublicationRuthenium complexes appear in scientific publications mainly as catalysts in the olefins metathesis process. In this review, we want to indicate the research niche regarding the use of ruthenium(II) and ruthenium(III) complexes in other catalytic processes, i.e. polymerization or epoxidation of olefins and depolymerization. We would like to combine the catalytic properties of ruthenium(II,III) complex compounds with their biomedical...
-
Organochlorine pesticides and polichlorinated biphenyls concentrations in fresh snowfall or top layer of snow from Hornsund region, Svalbard, in the spring 2019
Open Research DataThe dataset contains concentration of organochlorine persistent organic pollutants in snow samples collected from top layer of snow, which corresponded to fresh snowfall in most cases (except DS location, where these are 20 cm top layer sampled weekly). All snow samples have been collected within one month during spring 2019, in the vicinity of the...
-
Sval-POPs Spatial VAriabiLity: VALidation dataset on POPs concentrations in snow
ProjectsProject realized in Faculty of Chemistry according to 2018_0009 agreement
-
Influence of selenium and/or magnesium on alleviation alcohol induced oxidative stress in rats, normalization function of liver and changes in serum lipid parameters
Publication -
Territorial Extrapolation of Basic Data as a Solution of the Problem of Its Deficiency during Mass Appraisal
Publication -
Rationale and design of Mind-HF: randomized trial of the original Mindfulness-Based Heart Training for patients with heart failure
Publication -
J. Pawlak-Mikuć3, WEiA(ET) Ist, sem3, 22/23z
e-Learning Courses -
J. Pawlak-Mikuć , Bud, I st, 4 sem. l
e-Learning Courses -
J. Pawlak-Mikuć, WCH, II st, sem1, 21/22l
e-Learning Courses -
J. Pawlak-Mikuć, WCh, Ist, 5 sem, 21/22z
e-Learning Courses -
J. Pawlak-Mikuć, WCh, Ist, 4 sem, 20/21l
e-Learning Courses -
J. Pawlak-Mikuć, WZiE, I st, 2 sem, 2021I
e-Learning Courses -
J. Pawlak-Mikuć 5 Informatyka Ist sem2, 23/24
e-Learning Courses -
J. Pawlak-Mikuć ZiE IIst, sem 2, 24/25z
e-Learning Courses -
J. Pawlak-Mikuć WM Ist, sem 3, 24/25z
e-Learning Courses -
Measurement of plasma 25-hydroxyvitamin D2, 25-hydroxyvitamin D3 and 3-epi-25-hydroxyvitamin D3 in population of patients with cardiovascular disease by UPLC-MS/MS method
Publication -
The presence of bacterial microcolonies on the maxillary sinus ciliary epithelium in healthy young individuals
Publication -
Arterial Blood Pressure Features of Hypertensive Patients with Typical and Atypical 460 nm Skin Fluorescence Response to Transient Ischaemia
Publication -
A novel concept of negative CO2 emission power plant for utilization of sewage sludge
PublicationCarbon Capture and Storage (CSS) technology is considered an important “bridge technology”, allowing effective abatement of CO2 emissions for power units using fossil fuels. However, if biomass is used in a power plant, equipped with CCS system, negative CO2 emissions can be achieved. In practice, wide development of such technologies would enable not only reduction of CO2 emissions, but also reversal of the harm done so far. In...
-
Isolation and structure of a covalent cross-link adduct between mitomycin C and DNA
PublicationA DNA cross-link adduct of the antitumor agent mitomycin C (MC) to DNA has been isolated and characterized; the results provide direct proof for bifunctional alkylation of DNA by MC. Exposure of MC to Micrococcus luteus DNA under reductive conditions and subsequent nuclease digestion yielded adducts formed between MC and deoxyguanosine residues. In addition to the two known monoadducts, a bisadduct was obtained. Reductive MC activation...
-
Monosaccharides as Potential Chiral Probes for the Determination of the Absolute Configuration of Secondary Alcohols
PublicationHerein, a new method for the elucidation of the absolute configuration of chiral secondary alcohols is proposed. This method is an alternative for a widely used approach reported by Mosher and Dale and similar methods that are based on the 1H NMR shift (δ) changes of protons that are attached to the substituents of the oxymethine carbon atom. The presented method is not based on tracking the chemical shift changes and utilizes...
-
P.0253 Two-week lithium treatment modulates translocator protein expression in brain regions in the animal models of acute bipolar episodes
Publication -
J. Pawlak-Mikuć, WCH, II st, 1 sem, 20/21l
e-Learning Courses -
J. Pawlak-Mikuć, WZiE AG, II st, 2sem, 2020/2021I
e-Learning Courses -
J. Pawlak-Mikuć 6 ZiE Ist, sem 2, 23/24
e-Learning Courses