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Search results for: DRUM REPLACEMENT
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Bioactive silica-based drug delivery systems containing doxorubicin hydrochloride: In vitro studies
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Use of Materials Based on Polymeric Silica as Bone-Targeted Drug Delivery Systems for Metronidazole
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Silver Nanoparticles as Chlorhexidine and Metronidazole Drug Delivery Platforms: Their Potential Use in Treating Periodontitis
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ENCAPSULATION OF ROXITHROMYCIN INTO GELLAN GUM MATRICES AND THE IMPACT OF OTHER NATURAL POLYMERS ON DRUG RELEASE
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Drug-Releasing Antibacterial Coating Made from Nano-Hydroxyapatite Using the Sonocoating Method
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Cisplatin filled multiwalled carbon nanotubes – a novel molecular hybrid of anticancer drug container
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Elastic-contractile model proteins: Physical chemistry, protein function and drug design and delivery
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Drug transporter expression profiling in chemoresistant variants of the A2780 ovarian cancer cell line
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Microneedle‐Based Generation of Microbubbles in Cancer Tumors to Improve Ultrasound‐Assisted Drug Delivery
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The modulatory effect of green tea catechin on drug resistance in human ovarian cancer cells
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Acinetobacter baumannii isolated from hospital‐acquired infection: biofilm production and drug susceptibility
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Fulminant hepatic failure in woman with iron and non-steroidal anti-inflammatory drug intoxication
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Glucosamine-6-phosphate synthase,a novel target for antifungalagents.Molecular modelling studies in drug design
PublicationPraca dotyczy modelowania zarówno samych inhibitorów syntazy glukozamino-6-fosforanu jak i ich oddziaływania z obydwiema domenami tego enzymu. Enzym syntaza glukozamino-6-fosforanu został zaproponowany jako nowy cel molekularny w chemoterapii infekcji grzybowych. Zaprojektowano i zsyntezowano szereg inhibitorów tego enzymu - potencjalnych nowych leków przeciwgrzybowych. Dzięki modelowaniu molekularnemu udało się wyjaśnić mechanizm...
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Bovine Serum Albumin – Hydroxyapatite Nanoflowers as Potential Local Drug Delivery System of Ciprofloxacin
PublicationIntroduction: Hybrid nanoflowers are structures consisting of organic (enzymes, proteins, nucleic acids) and inorganic components (mostly metal phosphates) with a flower-like hierarchical structure. Novel hybrid nanoflowers based on bovine serum albumin (BSA) and hydroxyapatite (HA) were obtained and characterized. Study on BSA-HA nanoflowers as potential drug delivery system is reported for the first time. Methods: Embedding ciprofloxacin...
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Homoisocitrate dehydrogenase from Candida albicans: properties, inhibition, and targeting by an antifungal pro-drug
PublicationThe LYS12 gene from Candida albicans, coding for homoisocitrate dehydrogenase was cloned and expressed as a His-tagged protein in Escherichia coli. The purified gene product catalyzes the Mg2+- and K+-dependent oxidative decarboxylation of homoisocitrate to alpha-ketoadipate. The recombinant enzyme demonstrates strict specificity for homoisocitrate. SDS-PAGE of CaHIcDH revealed its molecular mass of 42.6±1 kDa, while in size-exclusion...
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Drug-Eluting Biopsy Needle as a Novel Strategy for Antimicrobial Prophylaxis in Transrectal Prostate Biopsy
PublicationOBJECTIVES: To preclinically evaluate drug-eluting biopsy needles (patent pending WO2016118026) as a new potential way of antimicrobial prophylaxis for transrectal prostate biopsy. METHODS: Twenty steel biopsy needles have been coated with polyvinyl alcohol, ciprofloxacin, and amikacin. Modified biopsy needles have been randomly divided into 3 groups (1:2:1 ratio). Needles from group I were immersed for 30 minutes in dedicated...
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Nanosize effect of clay mineral nanoparticles on the drug diffusion processes in polyurethane nanocomposite hydrogels
PublicationStudies of swelling and release of naproxen sodium (NAP) solution by polyurethane nanocomposite hydrogels containing Cloisite® 30B (organically modified montmorillonite (OMMT)) have been performed. Polyurethane nanocomposite hydrogels are hybrid, nontoxic biomaterials with unique swelling and release properties in comparison with unmodified hydrogels. These features enable to use nanocomposite hydrogels as a modern wound dressing....
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Możliwości modelowania rozkładu naprężeń i odkształceń w endoprotezie stawu biodrowego w układzie implant - kość z uwzględnieniem własności materiałowych = Possibility of stress and strain modelling in total hip replacement in implant-bone system including material properties
PublicationW pracy przedstawiono możliwości wykorzystania numerycznych technik komputerowych do modelowania rozkładu naprężeń i odkształceń w endoprotezie stawu biodrowego w układzie implant-kość z uwzględnieniem własności materiałowych elementów endoprotezy. Przedstawiono komputerowe modele służące do analizy naprężeń i odkształceń w endoprotezie wykonane przy wykorzystaniu metody elementów skończonych. Metody modelowania naprężeń i odkształceń...
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DRUG AND CHEMICAL TOXICOLOGY
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DRUG METABOLISM AND DISPOSITION
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DRUG DEVELOPMENT RESEARCH
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DRUG METABOLISM REVIEWS
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ASSAY AND DRUG DEVELOPMENT TECHNOLOGIES
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ARZNEIMITTEL-FORSCHUNG-DRUG RESEARCH
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Expert Opinion On Drug Safety
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American Health and Drug Benefits
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Drug Delivery and Translational Research
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Expert Opinion on Drug Delivery
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Journal of Drug Metabolism & Toxicology
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International Journal of Drug Discovery
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Expert Opinion on Drug Discovery
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FOOD AND DRUG LAW JOURNAL
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Drug Healthcare and Patient Safety
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Clinical Pharmacology in Drug Development
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INTERNATIONAL JOURNAL OF DRUG POLICY
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Journal of Drug Policy Analysis
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Current drug abuse reviews
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Infectious Disorders - Drug Targets
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Journal of Nanopharmaceutics and Drug Delivery
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Drug Discovery Today: Technologies
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Therapeutic Advances in Drug Safety
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Adverse Drug Reaction Bulletin
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Current Drug Discovery Technologies
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Drug Safety - Case Reports
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Journal of Alcohol and Drug Education
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Journal of Drug and Alcohol Research
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Drug Metabolism and Personalized Therapy
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Adverse Drug Reactions Journal
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Cancer Drug Discovery and Development
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NATURE REVIEWS DRUG DISCOVERY
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