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Search results for: autonomiczne agenty
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The use of eLearning strategies among travel agents in the United Kingdom, India and New Zealand
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Structural Characterization and in Vivo Evaluation of β-Hairpin Peptidomimetics as Specific CXCR4 Imaging Agents
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Fermented juices as reducing and capping agents for the biosynthesis of size-defined spherical gold nanoparticles
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When Membership Gives Strength to Act: Inclusion of the Group Into the Self and Feeling of Personal Agency
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Tackling Alzheimer's disease: Hypothetical synergism between anti-inflammatory and anti-diabetic agents
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High resolution model for assessment of contamination by chemical warfare agents dumped in the Baltic Sea
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Travel agents and destination management organizations: eLearning as a strategy to train tourism trade partners.
PublicationThis article offers an overview of the existing online courses run by national destination management organizations (DMOs) in order to better equip travel agents and tour operators in the sales activities of the tourism destinations. These online courses represent one of the B2B offers by DMOs and an interesting opportunity for travel agents, who are trying to find their identity and competitive advantage within the context of...
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Indole-Acrylonitrile Derivatives as Potential Antitumor and Antimicrobial Agents—Synthesis, In Vitro and In Silico Studies
PublicationA series of 2-(1H-indol-2-yl)-3-acrylonitrile derivatives, 2a–x, 3, 4a–b, 5a–d, 6a–b, and 7, were synthesized as potential antitumor and antimicrobial agents. The structures of the prepared compounds were evaluated based on elemental analysis, IR, 1H- and 13NMR, as well as MS spectra. X-ray crystal analysis of the representative 2-(1H-indol-2-yl)-3-acrylonitrile 2l showed that the acrylonitrile double bond was Z-configured. All...
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The effect of new non-cross resistant antitumor agents on the energy state of human erythrocytes
PublicationPrzebadano pochodne benzoperimidynowe i antrapirydonowe odnośnie ich wpływu na stan energetyczny ludzkich erytrocytów. Stwierdzono, że poziom nukleotydów jak i wartość AEC erytrocytów nie zmienił się w ciągu 24 h inkubacji z powyższymi związkami. Jest to wynik obiecujący w odniesieniu do ich zastosowania jako związków aktywnych w pokonywaniu oporności wielolekowej.
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Synchronizacja wiedzy w systemach agentowych
PublicationAgenty inteligentne są jednym z komponentów stosowanych w pro- jektowaniu rozproszonych inteligentnych systemów obliczeniowych. W rozdziale wskazano istotne aspekty systemów agentowych, a na- stępnie omówiono wybrane metody synchronizacji wiedzy między agentami będącymi częścią systemu agentowego. Omówiono podej- ście właściwe dla agentów zaufanych oraz jego modyfikację dla agen- tów, które mogą celowo próbować wprowadzać inne...
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Possiblities of application of recombined lysostaphin as an alternative agent in the therapy of Staphylococcus aureus mastitis
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Characterization of a Unique Bordetella bronchiseptica vB_BbrP_BB8 Bacteriophage and Its Application as an Antibacterial Agent
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Influence of the glycolysis agent on the structure of the glycolysates obtained from polyether-urethane wastes
PublicationW pracy zaprezentowano wybrane wyniki badań wpływu środków glikolizujących na strukturę glikolizatów otrzymywanych w procesie glikolizy odpadowych pianek polietero-uretanowych.
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Investigation of polyurethane elastomer–steel joints using glass lacquer as an adhesive agent
PublicationThis article describes an innovative method of coupling polyurethane elastomer (based on polyurethane glycolysate) with constructional steel, by implementation of a Glaspur®—glass lacquer containing latent polyurethanes and monosilane adhesion promoters. The commonly applied coupling agent is Cilbond® 45SF glue or its derivatives. Additionally, glycolysate was synthesised from polyurethane waste and 1,3-propylene glycol in 6:1...
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Agent System for Managing Distributed Mobile Interactive Documents in Knowledge-Based Organizations
PublicationThe MIND architecture of distributed mobile interactive document is a new processing model defined to facilitate obtaining a proper solution in knowledge processes carried out by knowledge-based organizations. Such organizations have an established structure that defines document templates and knowledge process. The aim of the MIND architecture is to change the static document to mobile agents, which are designed to implement the...
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Examining the Impact of Squaric Acid as a Crosslinking Agent on the Properties of Chitosan-Based Films
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Eradication of LIG4-deficient glioblastoma cells by the combination of PARP inhibitor and alkylating agent
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Phytotoxic Metabolites Produced by Diaporthella cryptica, the Causal Agent of Hazelnut Branch Canker
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Detailed investigation on FAME capped metal nanocomposite synthesis as potential antifungal agent
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Predation-Related Costs and Benefits of Conspecific Attraction in Songbirds—An Agent-Based Approach
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Defective TiO2 for CO2 photoreduction: Influence of alkaline agent and reduction temperature modulation
PublicationThis study investigates the synthesis and characterization of Black TiO2 photocatalyst (TiO2-x) through the sol-gel method combined with NaBH4 reduction at different temperatures (350 °C, 500 °C, and 650 °C). The photocatalytic performance for CO2 reduction was evaluated, revealing that TiO2-x_500°C sample exhibited the highest efficiency. This enhanced performance is mainly attributed to a higher concentration of oxygen vacancies...
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Zastosowania ontologii: Charakterystyczne cechy agentów semantycznych
PublicationNa podstawie reprezentatywnych przykładów podjeto próbę zilustrowania spektrum zastosowań agentów programowych. Wskazano główne cechy wyrózniajace poszczególne rodzaje agentów oraz ich atrybuty niezbędne dla omawianych zastosowań.
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Combretastatin A-4 and its analogues as antineoplastic agenst.
PublicationCombretastatyna A-4 jest naturalnym związkiem wyizolowanym z wierzby afrykańskiej Combretum caffrum. W pracy opisano syntezę i aktywność biologiczną combretastatyny A-4 i jej analogów jako potencjalnych inhibitorów angiogenezy.
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Bilet, wracam od Agaty
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Anti-Inflammatory and Anti-Allergy Agents in Medicinal Chemistry
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Międzynarodowe Agendy Badawcze MAB - spotkanie informacyjne ON-LINE
Eventstransmisja on-line w jęz. angielskim na kanale Fundacji na Rzecz Nauki Polskiej na portalu YouTube; w trakcie spotkania istnieje możliwość zadawania pytań drogą elektroniczną - e-mail: infodaymab@fnp.org.pl; zapis transmisji będzie dostępny na portalu YT natychmiast po zakończeniu spotkania. Agenda spotkania: kwestie dotyczące programu, możliwości i...
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Solid phase microextraction combined with chromatography - a powerful tool for determination of warfare agents and related compounds
PublicationOpisano zastosowanie mikroekstrakcji do fazy stacjonarnej do izolacji wzbogacania środków bojowych i produktów ich degradacji w powietrzu, wodzie i glebie oraz próbkach bilogicznych. Na etapie oznaczeń końcowych stosuje się najczęściej chromatografię gazową. Anality można pobierać przez bezpośrednie zanurzenie włókna w próbce ciekłej i gazowej oraz w fazie nadpowierzchniowej. Stosując SPME-GC można osiągnąć niskie granice oznaczalności...
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One-Step Synthesis of W/O and O/W Emulsifiers in the Presence of Surface Active Agents
PublicationThe main goal of this study was to describe the method of the synthesis of the dodecyl-, tetradecyl-, hexadecyl- and octadecyl-propylene glycol emulsifiers in the presence of selected anionic and nonionic surfactants. Acyl propylene glycol emulsifiers were produced by esterification of propane-1,2-diol (propylene glycol, PG) with C12:0-C18:0 fatty acids in the presence of anionic sodium dodecyl sulfate (SDS) and nonionic-poly(ethylene...
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Synthesis and biological activity of ester derivatives of mycophenolic acid and acridines/acridones as potential immunosuppressive agents
PublicationImproved derivatives of mycophenolic acid (MPA) are necessary to reduce the frequency of adverse effects, this drug exerts in treated patients. In this study, MPA was coupled with N-(x-hydroxyalkyl)-9-acridone-4-carboxamides or N-(x-hydroxyalkyl)acridine-4-carboxamides to give respective ester conjugates upon Yamaguchi protocol. This esterification required protection of phenol group in MPA. Designed conjugates revealed higher...
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Complexing and Chelating Agents Immobilized on Silica Gel and Related Materials and Their Application for Sorption of Inorganic Species
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Fixed-Dose Combination of NSAIDs and Spasmolytic Agents in the Treatment of Different Types of Pain—A Practical Review
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Bacteriophage-encoded enzymes destroying bacterial cell membranes and walls, and their potential use as antimicrobial agents
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Bacterial cellulose vs. bacterial cellulose nanocrystals as stabilizer agents for O/W pickering emulsions
PublicationThe growing interest in Pickering emulsions in functional food systems resulted in the need to find suitable stabilizers for them. The work considers the use of bacterial cellulose for this purpose, and its aim was to compare the properties of disintegrated bacterial cellulose, before and after freeze-drying, and its nanocrystals obtained using H2SO4 under variable of time and concentration conditions. The structure of nanocrystals...
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Conversion of Biomass and Municipal Wastes into Syngas and Hydrogen using Highly Preheated Agent (HTAG)
PublicationGasification is considered to be one of the most promising energy recovery technologies for the widespread utilization of biomass and wastes. During this process raw feedstock is converted into a combustible gas, which can then be burnt to produce thermal energy, or to run engines for mechanical or electrical power. The studies of biomass gasification demonstrate it as a friendly alternative to fossil fuels as one of renewable...
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Experimental Evaluation of the Agent-Based Population Learning Algorithm for the Cluster-Based Instance Selection
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Softwood-lignin/natural rubber composites containing novel plasticizing agent: Preparation and characterization
PublicationComposite materials based on natural rubber were obtained by using glycerolysate (decomposition prod- uct of polyurethane) as a novel plasticizer. In order to determine the effect of various lignin content, four different filler amounts were used, namely, 5 phr (parts per 100 parts of natural rubber) of lignin (WLI5G), 10 phr (WLI10G), 20 phr (WLI20G), and 40 phr (WLI40G). The reference specimen without lignin (WLI0G) was also...
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Multi-agent large-scale parallel crowd simulation with NVRAM-based distributed cache
PublicationThis paper presents the architecture, main components and performance results for a parallel and modu-lar agent-based environment aimed at crowd simulation. The environment allows to simulate thousandsor more agents on maps of square kilometers or more, features a modular design and incorporates non-volatile RAM (NVRAM) with a fail-safe mode that can be activated to allow to continue computationsfrom a recently analyzed state in...
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Electrochemical formation of the adduct between antitumor agent C_1311 and DNA nucleoside dG. 75.
PublicationPrzyjmuje się, że metaboliczna aktywacja przeciwnowotworowej pochodnej C_1311 jest procesem koniecznym dla jej aktywności przeciwnowotworowej. Wykazano wcześniej, że taka aktywacja prowadzi do kowalencyjnego wiązania się leku z DNA w komórce nowotworowej. Aby zbadać molekularny mechanizm powyższej reakcji metabolicznej przeprowadzono badania elektrochemicznego utleniania pochodnej C_1311. Wykazano w pracy, że dwa produkty elektrochemicznego...
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Globalizacja, wojna o talenty a zarządzanie zasobami ludzkimi
PublicationSukces rynkowy organizacji w warunkach nowej gospodarki zależy coraz częściej od umiejętności przyciągnięcia, utrzymania w firmie, rozwoju i efektywnego wykorzystania pracowników o wysokim potencjale, a więc talentów. Na początku opracowania omówiono wpływ zmian rynkowych na wzrost znaczenia kapitału ludzkiego i tworzenie koncepcji zarządzania talentami. Następnie przedstawiono - z perspektywy międzynarodowej i polskiej - zjawisko...
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Agenda: Empowering Women for Gender Equity
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Agenda-A Journal of Policy Analysis and Reform
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Practical Application of Intelligent Agents and Multi-Agent Technology Conference
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European Workshop on Modelling Autonomous Agents in a Multi-Agent World
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The Setting Time of Polyether Impression Materials after Contact with Conventional and Experimental Gingival Margin Displacement Agents
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Phthalocyanine Derivatives Possessing 2-(Morpholin-4-yl)ethoxy Groups As Potential Agents for Photodynamic Therapy
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Metabolic Profiles of New Unsymmetrical Bisacridine Antitumor Agents in Electrochemical and Enzymatic Noncellular Systems and in Tumor Cells
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Sonochemical synthesis of rosuvastatin based novel 3-methyleneisoindolin-1-one derivatives as potential anticancer agents
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Novel chalcone-derived pyrazoles as potential therapeutic agents for the treatment of non-small cell lung cancer
PublicationLung cancer is considered to account for approximately one-fifth of all malignant tumor-related deaths worldwide and is therefore one of the most lethal malignancies. Pyrazole scaffold possesses a wide range of biological and pharmacological activities, which play important roles in medicinal chemistry. The present study reports the synthesis and in vitro biological characterization of nine pyrazoles derived from chalcones as potential...
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Chloroacridine derivatives as potential anticancer agents which may act as tricarboxylic acid cycle enzyme inhibitors
PublicationThe chloroacridines affect biological forms of melanoma in different ways. Amelanotic (Ab) melanoma (with inhibited melanogenesis and higher malignancy) was particularly sensitive to the action of the chloroacridines. The Ab melanoma cells died through apoptosis and through death without caspase activation. Diminished activity of TAC enzymes was noticed among Ab melanoma cells together with ATP/NAD depletion, especially in the...
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Design of new cholinesterase inhibitors based on phosphorus analogs of tacrine as potential anti-Alzheimer’s disease agents
PublicationBased on the analysis of the determined free binding energy (using the AutoDock Vina 1.1.2 docking program), the most potent cholinesterase inhibitors were selected. Moreover, studies of 3D visualization of the results of molecular modeling led to the identification of potential sites for the interaction of new potential inhibitors with amino acid residues building active sites of investigated cholinesterases.