Filters
total: 1435
-
Catalog
displaying 1000 best results Help
Search results for: illicit drugs
-
Acinetobacter baumannii isolated from hospital‐acquired infection: biofilm production and drug susceptibility
Publication -
Fulminant hepatic failure in woman with iron and non-steroidal anti-inflammatory drug intoxication
Publication -
Bovine Serum Albumin – Hydroxyapatite Nanoflowers as Potential Local Drug Delivery System of Ciprofloxacin
PublicationIntroduction: Hybrid nanoflowers are structures consisting of organic (enzymes, proteins, nucleic acids) and inorganic components (mostly metal phosphates) with a flower-like hierarchical structure. Novel hybrid nanoflowers based on bovine serum albumin (BSA) and hydroxyapatite (HA) were obtained and characterized. Study on BSA-HA nanoflowers as potential drug delivery system is reported for the first time. Methods: Embedding ciprofloxacin...
-
New Life of an Old Drug: Caffeine as a Modulator of Antibacterial Activity of Commonly Used Antibiotics
Publication -
The Current Use of Mass Spectrometry in Combination with Other Separation Techniques in Drug Discovery Arena
Publication -
Drug-Eluting Biopsy Needle as a Novel Strategy for Antimicrobial Prophylaxis in Transrectal Prostate Biopsy
PublicationOBJECTIVES: To preclinically evaluate drug-eluting biopsy needles (patent pending WO2016118026) as a new potential way of antimicrobial prophylaxis for transrectal prostate biopsy. METHODS: Twenty steel biopsy needles have been coated with polyvinyl alcohol, ciprofloxacin, and amikacin. Modified biopsy needles have been randomly divided into 3 groups (1:2:1 ratio). Needles from group I were immersed for 30 minutes in dedicated...
-
Homoisocitrate dehydrogenase from Candida albicans: properties, inhibition, and targeting by an antifungal pro-drug
PublicationThe LYS12 gene from Candida albicans, coding for homoisocitrate dehydrogenase was cloned and expressed as a His-tagged protein in Escherichia coli. The purified gene product catalyzes the Mg2+- and K+-dependent oxidative decarboxylation of homoisocitrate to alpha-ketoadipate. The recombinant enzyme demonstrates strict specificity for homoisocitrate. SDS-PAGE of CaHIcDH revealed its molecular mass of 42.6±1 kDa, while in size-exclusion...
-
Nanosize effect of clay mineral nanoparticles on the drug diffusion processes in polyurethane nanocomposite hydrogels
PublicationStudies of swelling and release of naproxen sodium (NAP) solution by polyurethane nanocomposite hydrogels containing Cloisite® 30B (organically modified montmorillonite (OMMT)) have been performed. Polyurethane nanocomposite hydrogels are hybrid, nontoxic biomaterials with unique swelling and release properties in comparison with unmodified hydrogels. These features enable to use nanocomposite hydrogels as a modern wound dressing....
-
DRUGS OF THE FUTURE
Journals -
Modeling of pharmaceuticals mixtures toxicity with deviation ratio and best-fit functions models
PublicationThe present study deals with assessment of ecotoxicological parameters of 9 drugs (diclofenac (sodium salt), oxytetracycline hydrochloride, fluoxetine hydrochloride, chloramphenicol, ketoprofen, progesterone, estrone, androstenedione and gemfibrozil), present in the environmental compartments at specific concentration levels, and theirmutual combinations by couples against Microtox® and XenoScreen YES/YAS® bioassays. As the quantitative...
-
Analiza modalna konstrukcji podpierającej stanowiska badawczego dynamiki małogabarytowych wirników część druga - badania symulacyjne
PublicationCelem niniejszej pracy było przedstawienie badań eksperymentalnych oraz symulacyjnych stanowiska VIBstand. W pracy przedstawiono dokładne wyniki badań symulacyjnych, oraz skrótowo wyniki badań eksperymentalnych w celu porównania wyników. Dokładne wyniki badań eksperymentalnych przedstawione zostały części pierwszej artykułu (Analiza modalna konstrukcji podpierającej stanowiska badawczego dynamiki małogabarytowych wirników. Część...
-
DRUG AND CHEMICAL TOXICOLOGY
Journals -
DRUG METABOLISM AND DISPOSITION
Journals -
DRUG DEVELOPMENT RESEARCH
Journals -
DRUG METABOLISM REVIEWS
Journals -
ASSAY AND DRUG DEVELOPMENT TECHNOLOGIES
Journals -
ARZNEIMITTEL-FORSCHUNG-DRUG RESEARCH
Journals -
Expert Opinion On Drug Safety
Journals -
American Health and Drug Benefits
Journals -
Drug Delivery and Translational Research
Journals -
Expert Opinion on Drug Delivery
Journals -
Drug Design Development and Therapy
Journals -
Journal of Drug Metabolism & Toxicology
Journals -
International Journal of Drug Discovery
Journals -
Expert Opinion on Drug Discovery
Journals -
DRUG DEVELOPMENT AND INDUSTRIAL PHARMACY
Journals -
FOOD AND DRUG LAW JOURNAL
Journals -
Drug Healthcare and Patient Safety
Journals -
Clinical Pharmacology in Drug Development
Journals -
INTERNATIONAL JOURNAL OF DRUG POLICY
Journals -
Journal of Drug Policy Analysis
Journals -
Current drug abuse reviews
Journals -
Infectious Disorders - Drug Targets
Journals -
Journal of Nanopharmaceutics and Drug Delivery
Journals -
Drug Discovery Today: Technologies
Journals -
Therapeutic Advances in Drug Safety
Journals -
Adverse Drug Reaction Bulletin
Journals -
Current Drug Discovery Technologies
Journals -
Drug Safety - Case Reports
Journals -
Journal of Alcohol and Drug Education
Journals -
Journal of Drug and Alcohol Research
Journals -
Drug Metabolism and Personalized Therapy
Journals -
Adverse Drug Reactions Journal
Journals -
Letters in Drug Design & Discovery
Journals -
JOURNAL OF FOOD AND DRUG ANALYSIS
Journals -
Cancer Drug Discovery and Development
Journals -
NATURE REVIEWS DRUG DISCOVERY
Journals -
Current Drug Research Reviews
Journals -
The Correlation between Physical Crosslinking and Water-Soluble Drug Release from Chitosan-Based Microparticles
Publication -
Double layer adhesive silicone dressing as a potential dermal drug delivery film in scar treatment
PublicationThe present studies focused on the evaluation of design of an adhesive silicone film intended for scar treatment. Developed silicone double layer film was examined in terms of its future relevance to therapy and applicability on the human skin considering properties which included in vitro permeability of water vapor and oxygen. In order to adapt the patches for medical use in the future there were tested such properties as...