Maternal smoking Modulates Fatty Acid Profile of Breast Milk - Publikacja - MOST Wiedzy


Maternal smoking Modulates Fatty Acid Profile of Breast Milk


AIM: We hypothesized that the fatty acid composition of breast milk can be affected by a smoking habit in the mother. Consequently, this study verified whether maternal smoking modulates, and if so to what extent, the breast milk fatty acid profile. METHODS: The study included 20 postpartum women who declared smoking more than five cigarettes daily throughout a period of pregnancy and lactation, and 136 non-smoking postpartum women. Breast milk samples were collected between the 17th and the 30th day after delivery. The samples were analyzed by means of High Resolution Gas Chromatography for overall content of saturated, monounsaturated and polyunsaturated fatty acids. RESULTS: Compared to non-smokers, smokers were characterized by significantly higher relative breast milk contents of fatty acids and monounsaturated fatty acids. Additionally smokers' breast milk had higher concentrations of selected saturated fatty acids, monounsaturated fatty acids and polyunsaturated fatty acids. Furthermore, smokers were characterized by significantly lower values of linoleic to arachidonic acid ratio, and n-6 to n-3 polyunsaturated fatty acids ratio. CONCLUSIONS: Aside from its other harmful consequences, smoking modulates the fatty acid profile of human milk. This article is protected by copyright. All rights reserved.


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Copyright (2013 Foundation Acta Pædiatrica. Published by John Wiley & Sons Ltd)

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artykuł w czasopiśmie wyróżnionym w JCR
Opublikowano w:
ACTA PAEDIATRICA nr 102, wydanie 8, strony 353 - 359,
ISSN: 0803-5253
Rok wydania:
Opis bibliograficzny:
Szlagatys-Sidorkiewicz A., Martysiak-Żurowska D., Krzykowski G., Zagierski M., Kamińska B.: Maternal smoking Modulates Fatty Acid Profile of Breast Milk// ACTA PAEDIATRICA. -Vol. 102, iss. 8 (2013), s.353-359
Cyfrowy identyfikator dokumentu elektronicznego (otwiera się w nowej karcie) 10.1111/apa.12276
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  1. Agostoni C, Marangoni F, Grandi F, Lammardo AM, Giovannini M, Riva E, et al. Earlier smoking habits are associated with higher serum lipids and lower milk fat and polyunsaturated fatty acid content in the first 6 months of lactation. Eur J Clin Nutr 2003; 57: 1466-72. otwiera się w nowej karcie
  2. Koletzko B, Agostoni C, Bergmann R, Ritzenthaler K, Shamir R. Physiological aspects of human milk lipids and implications for infant feeding: a workshop report. Acta Paediatr 2011; 100: 1405-15. otwiera się w nowej karcie
  3. Bitman J, Wood L, Hamosh M, Hamosh P, Mehta NR. Comparison of the lipid composition of breast milk from mothers of term and preterm infants. Am J Clin Nutr 1983; 38: 300-12. otwiera się w nowej karcie
  4. Molto-Puigmarti C, Castellote AI, Carbonell-Estrany X, Lopez- Sabater MC. Differences in fat content and fatty acid proportions among colostrum, transitional, and mature milk from women delivering very preterm, preterm, and term infants. Clin Nutr 2011; 30: 116-23. otwiera się w nowej karcie
  5. Peng Y, Zhou T, Wang Q, Liu P, Zhang T, Zetterstrom R, et al. Fatty acid composition of diet, cord blood and breast milk in Chinese mothers with different dietary habits. Prostaglandins Leukot Essent Fatty Acids 2009; 81: 325-30. otwiera się w nowej karcie
  6. Jackson MB, Lammi-Keefe CJ, Jensen RG, Couch SC, Ferris AM. Total lipid and fatty acid composition of milk from women with and without insulin-dependent diabetes mellitus. Am J Clin Nutr 1994; 60: 353-61. otwiera się w nowej karcie
  7. Johansson S, Wold AE, Sandberg AS. Low breast milk levels of long-chain n-3 fatty acids in allergic women, despite frequent fish intake. Clin Exp Allergy 2011; 41: 505-15. otwiera się w nowej karcie
  8. Bitman J, Hamosh M, Wood DL, Freed LM, Hamosh P. Lipid composition of milk from mothers with cystic fibrosis. Pediatrics 1987; 80: 927-32. otwiera się w nowej karcie
  9. Wannamethee SG, Lowe GD, Shaper AG, Rumley A, Lennon L, Whincup PH. Associations between cigarette smoking, pipe/ cigar smoking, and smoking cessation, and haemostatic and inflammatory markers for cardiovascular disease. Eur Heart J 2005; 26: 1765-73. otwiera się w nowej karcie
  10. Simon JA, Fong J, Bernert JT Jr, Browner WS. Relation of smoking and alcohol consumption to serum fatty acids. Am J Epidemiol 1996; 144: 325-34. otwiera się w nowej karcie
  11. Bachour P, Yafawi R, Jaber F, Choueiri E, Abdel-Razzak Z. Effects of smoking, mother's age, body mass index, and parity number on lipid, protein, and secretory immunoglobulin A concentrations of human milk. Breastfeed Med 2012; 7: 179-88. otwiera się w nowej karcie
  12. Ermis B, Yildirim A, Tastekin A, Ors R. Influence of smoking on human milk tumor necrosis factor-alpha, interleukin-1beta, and soluble vascular cell adhesion molecule-1 levels at postpartum seventh day. Pediatr Int 2009; 51: 821-4. otwiera się w nowej karcie
  13. Zagierski M, Szlagatys-Sidorkiewicz A, Jankowska A, Krzykowski G, Korzon M, Kaminska B. Maternal smoking decreases antioxidative status of human breast milk. J Perinatol 2012; 32: 593-7. otwiera się w nowej karcie
  14. Ermis B, Yildirim A, Ors R, Tastekin A, Ozkan B, Akcay F. Influence of smoking on serum and milk malondialdehyde, superoxide dismutase, glutathione peroxidase, and antioxidant potential levels in mothers at the postpartum seventh day. Biol Trace Elem Res 2005; 105: 27-36. otwiera się w nowej karcie
  15. McDonald SD, Perkins SL, Walker MC. Correlation between self-reported smoking status and serum cotinine during pregnancy. Addict Behav 2005; 30: 853-7. otwiera się w nowej karcie
  16. Pickett KE, Rathouz PJ, Kasza K, Wakschlag LS, Wright R. Self-reported smoking, cotinine levels, and patterns of smoking in pregnancy. Paediatr Perinat Epidemiol 2005; 19: 368-76. otwiera się w nowej karcie
  17. Association of Official Analytical Chemists. Method No 905.02. Official methods of analysis. 19th ed. Washington: Association of Official Analytical Chemists (AOAC), 1990. 18. International Standard ISO 5509:2000. Animal and vegetable fats and oils. Preparation of methyl esters of fatty acids, 2000. otwiera się w nowej karcie
  18. International Standard ISO 5508:1990. Animal and vegetable fats and oils. Analysis by gas chromatography of methyl esters of fatty acids. otwiera się w nowej karcie
  19. R Development Core Team. R: a language and environment for statistical computing. Vienna: R Foundation for Statistical Computing, 2011.
  20. Samper MP, Jimenez-Muro A, Nerin I, Marqueta A, Ventura P, Rodriguez G. Maternal active smoking and newborn body composition. Early Hum Dev 2012; 88: 141-5. otwiera się w nowej karcie
  21. Gerd AT, Bergman S, Dahlgren J, Roswall J, Alm B. Factors associated with discontinuation of breastfeeding before 1 month of age. Acta Paediatr 2012; 101: 55-60.
  22. Jones LL, Hashim A, McKeever T, Cook DG, Britton J, Leonardi-Bee J. Parental and household smoking and the increased risk of bronchitis, bronchiolitis and other lower respiratory infections in infancy: systematic review and meta- analysis. Respir Res 2011; 12: 5. otwiera się w nowej karcie
  23. Midgette AS, Baron JA, Rohan TE. Do cigarette smokers have diets that increase their risks of coronary heart disease and cancer? Am J Epidemiol 1993; 137: 521-9. otwiera się w nowej karcie
  24. Thompson RL, Pyke S, Scott EA, Thompson SG, Wood DA. Cigarette smoking, polyunsaturated fats, and coronary heart disease. Ann N Y Acad Sci 1993; 686: 130-9. otwiera się w nowej karcie
  25. Nasser R, Stephen AM, Goh YK, Clandinin MT. The effect of a controlled manipulation of maternal dietary fat intake on medium and long chain fatty acids in human breast milk in Saskatoon, Canada. Int Breastfeed J 2010; 5: 3. otwiera się w nowej karcie
  26. Lattka E, Rzehak P, Szabo E, Jakobik V, Weck M, Weyermann M, et al. Genetic variants in the FADS gene cluster are associated with arachidonic acid concentrations of human breast milk at 1.5 and 6 mo postpartum and influence the course of milk dodecanoic, tetracosenoic, and trans-9- octadecenoic acid concentrations over the duration of lactation. Am J Clin Nutr 2011; 93: 382-91. otwiera się w nowej karcie
  27. Lowe AJ, Thien FC, Stoney RM, Bennett CM, Hosking CS, Hill DJ, et al. Associations between fatty acids in colostrum and breast milk and risk of allergic disease. Clin Exp Allergy 2008; 38: 1745-51. otwiera się w nowej karcie
  28. Tinoco SM, Sichieri R, Setta CL, Moura AS, Carmo MG. n-3 polyunsaturated fatty acids in milk is associate to weight gain and growth in premature infants. Lipids Health Dis 2009; 8: 23. otwiera się w nowej karcie
  29. Auestad N, Scott DT, Janowsky JS, Jacobsen C, Carroll RE, Montalto MB, et al. Visual, cognitive, and language assessments at 39 months: a follow-up study of children fed formulas containing long-chain polyunsaturated fatty acids to 1 year of age. Pediatrics 2003; 112: e177-83. otwiera się w nowej karcie
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