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Wyniki wyszukiwania dla: ER
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Genetic and pharmacologic proteasome augmentation ameliorates Alzheimer’s-like pathology in mouse and fly APP overexpression models
PublikacjaThe proteasome has key roles in neuronal proteostasis, including the removal of misfolded and oxidized proteins, presynaptic protein turnover, and synaptic efficacy and plasticity. Proteasome dysfunction is a prominent feature of Alzheimer’s disease (AD). We show that prevention of proteasome dysfunction by genetic manipulation delays mortality, cell death, and cognitive deficits in fly and cell culture AD models. We developed...
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Genetic and pharmacologic proteasome augmentation ameliorates Alzheimer’s-like pathology in mouse and fly APP overexpression models
PublikacjaThe proteasome has key roles in neuronal proteostasis, including the removal of misfolded and oxidized proteins, presynaptic protein turnover, and synaptic efficacy and plasticity. Proteasome dysfunction is a prominent feature of Alzheimer’s disease (AD). We show that prevention of proteasome dysfunction by genetic manipulation delays mortality, cell death, and cognitive deficits in fly and cell culture AD models. We developed...
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Motors of influenza vaccination uptake and vaccination advocacy in healthcare workers: A comparative study in six European countries
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Gastroesophageal Reflux Disease in Children with Interstitial Lung Disease
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Usage of Over-the-Counter and Herbal Products in Common Cold in Poland: Findings from Consumer Survey
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Prolonged pharmacological inhibition of cathepsin C results in elimination of neutrophil serine proteases
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Impact of European vaccination policies on seasonal influenza vaccination coverage rates: An update seven years later
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Children were less frequently infected with SARS-CoV-2 than adults during 2020 COVID-19 pandemic in Warsaw, Poland
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Pneumococcal vaccination among adults – updated Polish recommendations
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Evidence for consolidation of neuronal assemblies after seizures in humans
PublikacjaThe establishment of memories involves reactivation of waking neuronal activity patterns and strengthening of associated neural circuits during slow-wave sleep (SWS), a process known as "cellular consolidation" (Dudai and Morris, 2013). Reactivation of neural activity patterns during waking behaviors that occurs on a timescale of seconds to minutes is thought to constitute memory recall (O'Keefe and Nadel, 1978), whereas consolidation...
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Aggregated neutrophil extracellular traps resolve inflammation by proteolysis of cytokines and chemokines and protection from antiproteases
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Experimental review of the performances of protective coatings for interconnects in solid oxide fuel cells
PublikacjaFerritic stainless steel interconnects are used in solid oxide fuel cells; however, coatings are required to improve their performance. Although several types of coatings have been proposed, they have been scarcely investigated under similar conditions. This study compares the characteristics of uncoated Crofer 22 APU and eight different coatings on Crofer 22 APU for up to 3000 h at 800 ◦C. The coatings were deposited at various...
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Recommendations of the Polish Paediatric Society, the Polish Society of Vaccinology, and the Polish Society of Family Medicine on meningococcal vaccinations in children and adults in Poland
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Evaluation of the BNT162b2 Covid-19 Vaccine in Children 5 to 11 Years of Age
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Carbon-Coated Tellurium for Optical Data Storage
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Crystal growth of CsCl-type Yb0.24Sn0.76Ru
PublikacjaWzrost kryształów o stechiometrii Yb0.24Sn0.76Ru został przeprowadzony metodą topnikową. Kryształy poddano badaniom dyfrakcyjnym a także mikroskopii elektornowej. Yb0.24Sn0.76Ru krystalizuje w sześciennej strukturze typu chlorku cezu (CsCl).
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Analysis of 21 appendices from children with multisystem inflammatory syndrome compared to specimens of acute appendicitis – a new insight into MIS-C pathology
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A roadmap for a comprehensive control of cervical cancer in Poland: integration of available solutions into current practice in primary and secondary prevention
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Negative thermal expansion and antiferromagnetism in the actinide oxypnictide NpFeAsO
PublikacjaPrzeprowadzona został udana synteza NpFeAsO, związku będącego analogiem do LaFeAsO. Stwierdzono występowanie antyferromagnetycznego uporządkowania z T_N = 57 K. Poniżej T_N zauważono tzw. ujemną rozszerzalność termiczną. Przeprowadzono badania dyfrakcyjne przy użyciu promieniowania synchrotronowego (ESRF - Grenoble) a także neutronów (ILL - Grenoble).
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Polish consensus guidelines on the use of acyclovir in the treatment and prevention of VZV and HSV infections
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Plasma Amino Acids May Improve Prediction Accuracy of Cerebral Vasospasm after Aneurysmal Subarachnoid Haemorrhage
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Coalition Shaping the Vaccination Landscape
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Influence of different types of the internal system of the ballistic helmet shell on the thermal insulation measured by a manikin headform
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The role of colour preattentive processing in human–computer interaction task efficiency: A preliminary study
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The effects of graphical interface design characteristics on human–computer interaction task efficiency
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Simulation method for assessing the end of service life of gloves used by workers exposed to mineral oils and mechanical factors
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Evaluation of protective footwear fit for older workers (60+): A case study using 3D scanning technique
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Case study of the impact of toecap type on the microclimate in protective footwear
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Preliminary study evaluating manual dexterity tests assessing gloves protecting against cuts and stabs by hand knives
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Formation and Near-Infrared Emission of CsPbI3 Nanoparticles Embedded in Cs4PbI6 Crystals
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Phytotherapy and food applications from Brassica genus
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Adult pneumococcal vaccination – new opportunities
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Proteomic-Biostatistic Integrated Approach for Finding the Underlying Molecular Determinants of Hypertension in Human Plasma
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Updated principles of prevention, diagnosis and treatment of COVID-19 in children in Poland – recommendations for paediatricians and family medicine doctors
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New kagome prototype materials: discovery of KV3Sb5, RbV3Sb5, and CsV3Sb5
PublikacjaIn this work, we present our discovery and characterization of a new kagome prototype structure, KV3Sb5. We also present the discovery of the isostructural compounds RbV3Sb5 and CsV3Sb5. All materials exhibit a structurally perfect two-dimensional kagome net of vanadium. Density-functional theory calculations indicate that the materials are metallic, with the Fermi level in close proximity to several Dirac points. Powder and single-crystal...
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Independent Mechanisms Lead to Genomic Instability in Hodgkin Lymphoma: Microsatellite or Chromosomal Instability
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Driver Fatigue and Road Safety on Poland’s National Roads
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Effect of previous lowering of skin temperature on the time of safe exposure to a hot environment: a case study
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The influence of air humidity on human heat stress in a hot environment
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Thermal Sensations of Surgeons During Work in Surgical Gowns
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Physiological tests on firefighters whilst using protective clothing
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Information presentation compatibility in a simple digital control panel design: eye-tracking study
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Driver Fatigue and Road Safety on Poland's National Roads
PublikacjaThis paper presents an overview of factors causing driver fatigue as described in the literature. Next, a traffic crash database for 2003–2007 is used to identify the causes, circumstances and consequences of accidents caused by driver fatigue on Poland’s national roads. The results of the study were used to build a model showing the relationship between the concentration of road accidents and casualties, and the time of day. Finally,...
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Problems of Railway Noise—A Case Study
PublikacjaUnder Directive 2002/49/EC relating to the assessment and management of environmental noise, all European countries are obliged to model their environmental noise levels in heavily populated areas. Some countries have their own national method, to predict noise but most have not created one yet. The recommendation for countries that do not have their own model is to use an interim method....
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Problems of Railway Noise-A Case Study
PublikacjaUnder Directive 2002/49/EC relating to the assessment and management of environmental noise, all European countries are obliged to model their environmental noise levels in heavily populated areas. Some countries have their own national method, to predict noise but most have not created one yet. The recommendation for countries that do not have their own model is to use an interim method. The Dutch SRM II scheme is suggested for...
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Determination of paraffin oil mist penetration at high flow rates through air-purifying respirators
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Aspects of Tests and Assessment of Filtering Materials Used for Respiratory Protection Against Bioaerosols. Part II: Sweat in the Environment, Microorganisms in the Form of a Bioaerosol
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A Contribution to the Study of the Antidust Respirators’ Real Performance
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Efficiency of Filtering Materials Used in Respiratory Protective Devices Against Nanoparticles
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Aspects of Tests and Assessment of Filtering Materials Used for Respiratory Protection Against Bioaerosols. Part I: Type of Active Substance, Contact Time, Microorganism Species
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