Filtry
wszystkich: 5333
wybranych: 4292
-
Katalog
- Publikacje 4292 wyników po odfiltrowaniu
- Czasopisma 263 wyników po odfiltrowaniu
- Konferencje 24 wyników po odfiltrowaniu
- Osoby 135 wyników po odfiltrowaniu
- Projekty 2 wyników po odfiltrowaniu
- Zespoły Badawcze 1 wyników po odfiltrowaniu
- Kursy Online 109 wyników po odfiltrowaniu
- Wydarzenia 5 wyników po odfiltrowaniu
- Dane Badawcze 502 wyników po odfiltrowaniu
Filtry wybranego katalogu
wyświetlamy 1000 najlepszych wyników Pomoc
Wyniki wyszukiwania dla: HUMAN-RELATED BACTERIA
-
Prevalence of Closely Related Candida albicans Species among Patients with Vulvovaginal Candidiasis in Southern Poland Based on the hwp1 Gene Amplification
Publikacja -
Kallikrein-related peptidase 14 activates zymogens of membrane type matrix metalloproteinases (MT-MMPs) - a CleavEx library-based analysis
Publikacja -
Changes in Epigenetic Patterns Related to DNA Replication in Vicia faba Root Meristem Cells under Cadmium-Induced Stress Conditions
PublikacjaExperiments on Vicia faba root meristem cells exposed to 150 µM cadmium chloride (CdCl2) were undertaken to analyse epigenetic changes, mainly with respect to DNA replication stress. Histone modifications examined by means of immunofluorescence labeling included: (1) acetylation of histone H3 on lysine 56 (H3K56Ac), involved in transcription, S phase, and response to DNA damage during DNA biosynthesis; (2) dimethylation of histone...
-
DNA-damaging imidazoacridinone C-1311 induces autophagy followed by irreversible growth arrest and senescence in human lung cancer cells
PublikacjaImidazoacridinone 5-diethylaminoethylamino-8-hydroxyimidazoacridinone (C-1311) is an antitumor inhibitor of topoisomerase II and FMS-like tyrosine kinase 3 receptor. In this study, we describe the unique sequence of cellular responses to C-1311 in human non-small cell lung cancer (NSCLC) cell lines, A549 and H460. In A549 cells, C-1311 (IC80 = 0.08 µM) induced G1 and G2/M arrests, whereas H460 cells (IC80 = 0.051 µM) accumulated...
-
Combined anticancer therapy with imidazoacridinone analogue C‐1305 and paclitaxel in human lung and colon cancer xenografts—Modulation of tumour angiogenesis
PublikacjaThe acridanone derivative 5-dimethylaminopropylamino- 8- hydroxytriazoloacridinone (C-1305) has been described as a potent inhibitor of cancer cell growth. Its mechanism of action in in vitro conditions was attributed, among others, to its ability to bind and stabilize the microtubule network and subsequently exhibit its tumour- suppressive effects in synergy with paclitaxel (PTX). Therefore, the objective of the present study...
-
Sound Field Intensity Measurements and Visualization around the Human Head Model . Rozkłąd natężenia pola akustycznego w komorze bezechowej obecności sztucznej głowy i w przypadku braku jej obecności
PublikacjaThe main goal of this research study was to measure and visualize sound field intensity distribution in and without presence of the human head model. Measurements were performed in the anechoic chamber with the 5 cm grid. Experimental setup consisted of a multitone generator, two loudspeakers, human head model, intensimetric probe, the Cartesian robot applied for precise positioning of the acoustic sensor, and an analyzer. Based...
-
When Biobanks Meet Religion: Association Between Religiosity and Attitudes of Polish Medical Students Toward Biobanking of Human Biological Material for Research Purposes
PublikacjaWhile biobanking is expanding globally, the empirical evidence concerning the impact of religion on future healthcare professionals’ awareness and willingness to donate biospecimens for biobank research is lacking. To understand how medicalstudents’ religious beliefs can fuel their questions regarding how biospecimens would be stored, cared for, and used, we conducted a survey among 1500 medical students at Poznań University...
-
Induction of G2/M phase arrest and apoptosis of human pancreatic cancer BxPC-3 cells by potenet antitumor 1-nitroacridine derivative C-1748
PublikacjaPancreatic ductal adenocarcinoma (PDA) is among the most lethal human cancers, in part because it is insensitive to many chemotherapeutic drugs. Gemcitabine still remains the best chemotherapeutic agent available for the treatment of advanced pancreatic cancer. However, gemcitabine treatment results in only a marginal survival advantage. Thus, there is a strong need for the continuous development of novel therapeutic agents...
-
Fluorescence studies by quenching and protein unfolding on the interaction of bioactive compounds in water extracts of kiwi fruit cultivars with human serum albumin
PublikacjaThe main aim of this investigation was to characterize new kiwi fruit cultivars after cold storage treatment and to determine the similarities and differences between them, using spectroscopic methods. The chemometric comparison of kiwi fruit cultivars based on physicochemical indices during cold storage was carried out. All kiwi fruit cultivars showed a high level of correlation between the contents of phenolic compounds (polyphenols,...
-
Human poverty - measuring relative deprivation from basic achievements: a comparative study for 144 countries over the period 1990-2010
PublikacjaPoverty – differently defined and measured – still remains one the crucial parts of the world development debate. It`s broadly perceived as multidimensional phenomenon which deprives people from basic capabilities and freedoms, limits their opportunity to educate and fully participate in the labor market contributing to overall country`s socioeconomic performance. Referring to seminal works of Sen and many others(see e.g. Morris...
-
Modification of gradient HPLC method for determination of small molecules' affinity to human serum albumin under column safety conditions: Robustness and chemometrics study
PublikacjaIn the early stages of drug discovery, beyond the biological activity screening, determining the physicochemical properties that affect the distribution of molecules in the human body is an essential step. Plasma protein binding (PPB) is one of the most important investigated endpoints. Nevertheless, the methodology for measuring %PPB is significantly less popular and standardized than other physicochemical properties, like lipophilicity....
-
Trends in In Silico Approaches to the Prediction of Biologically Active Peptides in Meat and Meat Products as an Important Factor for Preventing Food-Related Chronic Diseases
Publikacja -
A Warrior Society: Data From 30 Countries Show That Belief in a Zero-Sum Game Is Related to Military Expenditure and Low Civil Liberties
Publikacja -
The Polish Version of the Yale-Brown Obsessive-Compulsive Scale, Modified to Reflect Obsessions and Compulsions Related to Heavy Drinking (YBOCS-hd-PL)
Publikacja -
Response to Letter to the Editors regarding article entitled ‘Sex-related patient-reported brain fog symptoms in nonhospitalised COVID-19 patients’
Publikacja -
Mutual Expression of ALDH1A1, LOX, and Collagens in Ovarian Cancer Cell Lines as Combined CSCs- and ECM-Related Models of Drug Resistance Development
Publikacja -
Fatty Acids Related Genes Expression Undergo Substantial Changes in Porcine Oviductal Epithelial Cells During Long-Term Primary Culture
Publikacja -
The Experiences of People with Dementia and Informal Carers Related to the Closure of Social and Medical Services in Poland during the COVID-19 Pandemic—A Qualitative Study
Publikacja -
Carbon fractionation and stable carbon isotopic fingerprint of road dusts near coal power plant with emphases on coal-related source apportionment
Publikacja -
Ambulatory Systolic Blood Pressure is Related to the Deletion Allele of the Angiotensin I Converting Enzyme Gene in Young Normotensives with Parental History of Hypertension
Publikacja -
Sensitivity of personalized ventilation air terminal device geometry with regard to a human thermal sensation
Publikacja -
A fully validated HPLC–UV method for determination of sulthiame in human serum/plasma samples
Publikacja -
New sorbent materials for selective extraction of cocaine and benzoylecgonine from human urine samples
Publikacja -
Does Human Potentiality Affect IT Professionals’ Organizational Behavior? An Experimental Study in Poland and Germany
Publikacja -
Robust HPLC–MS/MS method for levofloxacin and ciprofloxacin determination in human prostate tissue
Publikacja -
Enhancing human performance in ship operations by modifying global design factors at the design stage
Publikacja -
Optimization of Novel Human Acellular Dermal Dressing Sterilization for Routine Use in Clinical Practice
Publikacja -
IL-22 modulates inflammatory properties of human primary aortic smooth muscle cells
Publikacja -
Lipid mediators involved in the oxidative stress and antioxidant defence of human lung cancer cells
Publikacja -
Forms of mercury in the Baltic mussel (Mytilus trossulus): Human and ecosystem health risk assessment
Publikacja -
Mercury in marine fish, mammals, seabirds, and human hair in the coastal zone of the southern Baltic
Publikacja -
Response of a New Low-Coherence Fabry-Perot Sensor to Hematocrit Levels in Human Blood
Publikacja -
Sulforaphene, an isothiocyanate present in radish plants, inhibits proliferation of human breast cancer cells
Publikacja -
Is the Identification of SNP-miRNA Interactions Supporting the Prediction of Human Lymphocyte Transcriptional Radiation Responses?
Publikacja -
Immunophenotyping and transcriptional profiling of in vitro cultured human adipose tissue derived stem cells
PublikacjaAdipose-derived stem cells (ASCs) have become an important research model in regenerative medicine. However, there are controversies regarding the impact of prolonged cell culture on the ASCs phenotype and their differentiation potential. Hence, we studied 10 clinical ASCs replicates from plastic and oncological surgery patients, in six-passage FBS supplemented cultures. We quantified basic mesenchymal cell surface marker transcripts...
-
Effect of Maximal Breath Hold Apnea on Pial Artery Pulsation and Subarachnoid Width in Human
PublikacjaLittle is known about intracranial pressure (ICP)-cerebral hemodynamic interplay during maximal breath-hold apnea. A recently developed method based on near-infrared transillumination/backscattering sounding (NIR-T/BSS) noninvasively measures changes in pial artery pulsation (cc-TQ) as well as subarachnoid width (sas-TQ) in humans. Changes in sas-TQ correlate with ICP to a considerable extent, whereas cc-TQ reflects the functional...
-
The influence of fresh cabbage and sauerkraut juices on the activity of protective enzymes in human cell lines
PublikacjaMechanizmami przeciwrakotwórczego działania związków zawartych w kapuście jest m.in. metaboliczna aktywacja enzymów II fazy detoksykacji, indukcja enzymów naprawczych DNA oraz aktywnośc przeciwutleniająca. Do enzymów II fazy odtruwania należą m.in. S-transferazy glutationowe (GST) oraz oksydoreduktaza chinonowa NQO1 zwana też DT-diaforazą. GST katalizują reakcję sprzęgania glutationu z wieloma różnymi typami ksenobiotyków, ułatwiając...
-
Public Attitudes toward Biobanking of Human Biological Material for Research Purposes: A Literature Review
Publikacja -
Coexpression of human chorionic gonadotropin beta subunit and its receptor in nontrophoblastic gynecological cancer
Publikacja -
Ornamental Flowers Grown in Human Surroundings as a Source of Anthocyanins with High Anti-Inflammatory Properties
Publikacja -
Lysosome Alterations in the Human Epithelial Cell Line HaCaT and Skin Specimens: Relevance to Psoriasis
Publikacja -
Non-steroidal anti-inflammatory drugs are safe with respect to the transcriptome of human dermal fibroblasts
Publikacja -
MicroRNA expression profile analysis in human skeletal muscle tissue: Selection of critical reference
Publikacja -
PELP1 and SRC kinase as important molecules in the estrogen-mediated pathway in human testis and epididymis
Publikacja -
Influence of adalimumab on interleukin 12/23 signalling pathways in human keratinocytes treated with lipopolysaccharide A
Publikacja -
Apoptosis induction in C32 human melanoma cells by Jasione montana and its main phytoconstituents
Publikacja -
Metabolic transformations of antitumor imidazoacridinone, C-1311, with microsomal fractions of rat and human liver
Publikacja -
Local anaesthetics upregulate nitric oxide generation in cord blood and adult human neutrophils
Publikacja -
Expression of pendrin and NIS iodide transporters in human breast tumor and peri-tumoral tissue
Publikacja -
Metabolic transformations of antitumor imidazoacridinone, C-1311, with microsomal fractions of rat and human liver
PublikacjaWykazano, że enzymatyczna aktywacja jest konieczna dla aktywności biologicznej pochodnej C-1311 (Symadex R), która znajduje się w II fazie badań klinicznych. Zbadano przemiany enzymatyczne tego związku w obecności frakcji enzymatycznych mikrosomalnych komórek wątroby szczura i ludzkiej. Badania te wykazały, że związek C-1311 jest bardziej podatny na przemiany w obecności frakcji mikrosomalnej niż S9 i cytozolowej. Inkubacja związku...