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Wyniki wyszukiwania dla: LYME DISEASE, BORRELIA BURGDORFERI SENSU LATO, EPITOPE MAPPING, SERODIAGNOSIS, CHIMERIC PROTEINS
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Relationship between selected DNA polymorphisms and coronary artery disease complications
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Proteomic and lipidomic biomarkers in the diagnosis and progression of inflammatory bowel disease – a review
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Correction of Huntington’s Disease Phenotype by Genistein-Induced Autophagy in the Cellular Model
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Dual-task exercise as a therapy for executive motor function in Parkinson’s disease
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Oxidative DNA damage in cancer patients: a cause or a consequence of the disease development?
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Increased plasma concentrations of interleukin 35 in patients with coronary artery disease
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Multiplatform metabolomics provides insight into the molecular basis of chronic kidney disease
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THE COVID-19 DISEASE AND POLICY RESPONSE TO MITIGATE THE ECONOMIC IMPACT IN THE EU
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Intraoperative, Radio-Guided Sentinel Lymph Node Mapping in 110 Nonsmall Cell Lung Cancer Patients
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Blue-dye intraoperative sentinel lymph node mapping in early non-small cell lung cancer
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Protective and risk factors of cognitive decline and dementia with a special emphasis on social health: A systematic mapping review
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Mapping the Structural and Dynamic Determinants of pH-Sensitive Heparin Binding to Granulocyte Macrophage Colony Stimulating Factor
PublikacjaGranulocyte macrophage colony stimulating factor (GMCSF) is an immunomodulatory cytokine that is harnessed as a therapeutic. GMCSF is known to interact with other clinically important molecules, such as heparin, suggesting that endogenous and administered GMCSF has the potential to modulate orthogonal treatment outcomes. Thus, molecular level characterization of GMCSF and its interactions with biologically active compounds is critical...
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Mapping the Transglycosylation Relevant Sites of Cold-Adapted β-D-Galactosidase from Arthrobacter sp. 32cB
PublikacjaB-Galactosidase from Arthrobacter sp. 32cB (ArthbetaDG) is a cold-adapted enzyme able to catalyze hydrolysis of beta-D-galactosides and transglycosylation reaction, where galactosyl moiety is being transferred onto an acceptor larger than a water molecule. Mutants of ArthbetaDG D207A and E517Q were designed to determine the significance of specific residues and to enable formation of complexes with lactulose and sucrose and to...
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Differentially expressed proteins in the blood serum of piglets in response to a diet supplemented with inulin
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Proteins Structure Models in the Evaluation of Novel Variant (C.472_477del) in the MOCS2 Gene
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Cadmium tri-tert-butoxysilanethiolates. Structural and spectroscopic models of metal sites in proteins.
PublikacjaW publikacji opisano syntezy i struktury dla dwóch heteroleptycznych kompleksów kadmu z rdzeniem CdS2NO2 i CdS2N2. Bis(tri-tert-butoksysilanotiolato)(1-metyloimidazol)kadmu(II) oraz bis(tri-tert-butoksysilanotiolato)bis(1-metyloimidazol)kadmu(II) współistnieją w roztworze chloroformu przy różnych stężeniach Bis(tri-tert-butoksysilanotiolanu) kadmu(II) i 1 metyloimidazolu. Rotzwór ten został scharakteryzowany za pomocą analizy spektralnej...
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FT-Raman Spectroscopy as a Tool to Study the Secondary Structures of Wheat Gliadin Proteins
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Does Nitrogen Fertilization Affect the Secondary Structures of Gliadin Proteins in Hypoallergenic Wheat?
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Extension of the UNRES Coarse-Grained Force Field to Membrane Proteins in the Lipid Bilayer
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Crystal structures of the Bacillus subtilis prophage lytic cassette proteins XepA and YomS
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The Characteristics of New SSB Proteins from Metagenomic Libraries and Their Use in Biotech Applications
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Single-stranded DNA-binding proteins (SSBs) - sources and applicationsin molecular biology
PublikacjaBiałka wiążące się do jednoniciowego DNA (SSB) odgrywają ważną rolę w replikacji, rekombinacji i naprawie DNA u bakterii, archea i eukariota. Ostatnio wzrosło zainteresowanie białkami SSB jako przydatnymi narzędziami w metodach badawczych biologii molekularnej, analitycznych i diagnostycznych. Większość znanych prokariotycznych białek SSB zbudowanych jest z czterech podjednostek (homotetramer) z jedną domeną wiążąca (OB) jednoniciowe...
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DArTseq-Based High-Throughput SilicoDArT and SNP Markers Applied for Association Mapping of Genes Related to Maize Morphology
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Analysis of mHealth research: mapping the relationship between mobile apps technology and healthcare during COVID-19 outbreak
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Open tools for benthic habitat mapping: study of seagrass (posidonia oceanica) in the natural park of Cabo de Gata
PublikacjaW artykule przedstawiono koncepcję wykorzystania otwartego oprogramowania dostępnego poprzez interfejs WWW służącego do analizy materiału zebranego przez echosondy jednowiązkowe i sonary boczne pod kątem klasyfikacji rozmiaru wystąpienia traw morskich Posidonia Oceanica. Jako przyklad przedstawiono analizę danych z sonaru bocznego zebranych w zatoce Cabo de Gata.
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Least square spline modelling along with tin decimation for 3D seafloor mapping from multibeam sonar data.
PublikacjaPrzedstawiono wyniki prac związane z zastosowaniem algorytmu aproksymacyjnego minimalnokwadratowego do wizualizacji danych wysokorozdzielczych pochodzących z sonaru wielowiązkowego. Metoda pozwala na redukcję danych oraz łatwą ich modyfikację.
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Development of a tropical disease diagnosis system using artificial neural network and GIS
PublikacjaExpert systems for diagnosis of tropical diseases have been developed and implemented for over a decade with varying degrees of success. While the recent introduction of artificial neural networks has helped to improve the diagnosis accuracy of such systems, this aspect is still negatively affected by the number of supported diseases. A large number of supported diseases usually corresponds to a high number of overlapping symptoms,...
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Isolation and Characterization of NP-POL Nonapeptide for Possible Therapeutic Use in Parkinson’s Disease
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Ambulatory pulse pressure and its contributors in autosomal dominant polycystic kidney disease
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The Relationship Between Gene Polymorphisms and Dipping Profile in Patients With Coronary Heart Disease
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Ultra-rare ultra-care: The unique burden of ultra rare disease caregiving
PublikacjaBackground: We sought to assesses the impact of caring for children with ultra rare diseases (URDs) on familycarers and to analyse the way these experiences differ among the caregivers of children diagnosed throughprenatal or newborn screening, and those with symptom-based diagnosis.Methods: A total of 200 caregivers of 219 URDs children completed an on-line survey regarding the challengesand experiences...
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Exhaled nitric oxide in smokers and former smokers with chronic obstructive pulmonary disease
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Chromoblastomycosis as an endemic disease in temperate Europe: first confirmed case and review of the literature
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Chlorpromazine-induced hyperprolactinemia in a young female and its relation with fibrocystic breast disease
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Molecular Mechanisms Associated with ROS-Dependent Angiogenesis in Lower Extremity Artery Disease
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Investigating the disease‐modifying properties of sclerotiorin in Alzheimer's therapy using acetylcholinesterase inhibition
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Expert System as a classification method for optimal Legg-Calve-Perthes Disease treatment
PublikacjaZaproponowano utworzenie systemu eksperckiego jako metody klasyfikacji w prognozowaniu dowolnej formy leczenia dzieci z chorobą Legg-Calve-Perthesa. Obecnie nie ma jednego optymalnego sposobu leczenia choroby Perhtes'a i proponowana metoda jest próbą utworzenia wymiernego i uniwersalnego narzędzia, które będzie stanowiło podstawę przy podejmowaniu decyzji o najlepszym sposobie leczenia chorego stawu biodrowego. System ekspercki,...
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F05 Nine Hole Peg Test As A Measure Of Visuomotor Coordination In Huntington's Disease
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Deep Infiltrating Endometriosis in Adolescence: Early Diagnosis and Possible Prevention of Disease Progression
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SYNTHESIS OF PHOSPHORUS TACRINE ANALOGUES AS A NEW POTENTIAL ANTI-ALZHEIMER’S DISEASE AGENTS
PublikacjaA series of novel phosphorus tacrine derivatives was obtained in three steps, including synthesis of 9-chlorotacrine, connection of 9-chlorotacrine with hexamethylenediamine, 1,8-diaminooctane and 1,12-diaminododecane linkers and reaction of obtained tacrine diamine analogues with corresponding acid ester to give nine tacrine organophosphorus compounds. All of the obtained final structures were characterized by 1H NMR, 13C NMR,...
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Ocena akustycznego zagrożenia środowiska w związku z imprezą „Celtyckie lato w Gdyni” odbywającą się w muszli koncertowej na placu Grunwaldzkim w Gdyni w dniu 28.08.2016
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Optimized procedure of extraction, purification and proteomic analysis of nuclear proteins from mouse brain
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Electrodes Based on a Titanium Dioxide Nanotube–Spherical Silver Nanoparticle Composite for Sensing of Proteins
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Identification and properties of the psychrophilic bacterium Desulfolatea psychrophila single-stranded DNA binding proteins
PublikacjaTo study the biochemical properties of SSB from Desulfolatea psychrophila (DpsSSB), we have cloned the ssb genes obtained by PCR and have developed Escherichia coli overexpression systems. The gene consists of an open reading frame of 426 nucleotides encoding SSB protein of 142 amino acids with a calculated molecular mass of 15.6 kDa and it is the smallest known bacterial SSB protein indentified to date. The amino-acid sequence...
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Post mortem development of meat quality as related to changes in cytoskeletal proteins of chicken muscles
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Expression of INHβA and INHβB proteins in porcine oocytes cultured in vitro is dependent on the follicle size
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Elastic-contractile model proteins: Physical chemistry, protein function and drug design and delivery
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Efficient parallel algorithms in global optimization of potential energy functions for peptides, proteins, and crystals
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Interfacial water controls the process of adsorption of hyperactive antifreeze proteins onto the ice surface
PublikacjaA mechanism of interactions between the ice-binding surface of a hyperactive antifreeze protein molecule and the ice surface is proposed, involving the influence of water present between the two surfaces on the behavior of the approaching molecule. It is demonstrated that the interfacial water, even before its full solidification, can act as a factor that pushes away or pulls nearer the protein molecule to ensure its proper positioning....
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A novel chemiluminescent immunoassay for detection of Toxoplasma gondii IgG in human sera
PublikacjaThis study describes Toxoplasma gondii IgG chemiluminescent immunoassay (CLIA) based on the use of a novel immunochemical reagents in the form of the conjugates of original acridinium ester (AE) labels attached to antibodies and SAG2-GRA1-ROP1L chimeric antigen and shows that this test is useful for diagnostic purposes.