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Novel Highly Thermostable Endolysin from Thermus scotoductus MAT2119 Bacteriophage Ph2119 with Amino Acid Sequence Similarity to Eukaryotic Peptidoglycan Recognition Proteins
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Proteomic analysis of stipe explants reveals differentially expressed proteins involved in early direct somatic embryogenesis of the tree fern Cyathea delgadii Sternb
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Dietary chicory root and chicory inulin trigger changes in energetic metabolism, stress prevention and cytoskeletal proteins in the liver of growing pigs – a proteomic study
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DNA-damaging imidazoacridinone C-1311 induces autophagy followed by irreversible growth arrest and senescence in human lung cancer cells
PublikacjaImidazoacridinone 5-diethylaminoethylamino-8-hydroxyimidazoacridinone (C-1311) is an antitumor inhibitor of topoisomerase II and FMS-like tyrosine kinase 3 receptor. In this study, we describe the unique sequence of cellular responses to C-1311 in human non-small cell lung cancer (NSCLC) cell lines, A549 and H460. In A549 cells, C-1311 (IC80 = 0.08 µM) induced G1 and G2/M arrests, whereas H460 cells (IC80 = 0.051 µM) accumulated...
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Combined anticancer therapy with imidazoacridinone analogue C‐1305 and paclitaxel in human lung and colon cancer xenografts—Modulation of tumour angiogenesis
PublikacjaThe acridanone derivative 5-dimethylaminopropylamino- 8- hydroxytriazoloacridinone (C-1305) has been described as a potent inhibitor of cancer cell growth. Its mechanism of action in in vitro conditions was attributed, among others, to its ability to bind and stabilize the microtubule network and subsequently exhibit its tumour- suppressive effects in synergy with paclitaxel (PTX). Therefore, the objective of the present study...
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Sound Field Intensity Measurements and Visualization around the Human Head Model . Rozkłąd natężenia pola akustycznego w komorze bezechowej obecności sztucznej głowy i w przypadku braku jej obecności
PublikacjaThe main goal of this research study was to measure and visualize sound field intensity distribution in and without presence of the human head model. Measurements were performed in the anechoic chamber with the 5 cm grid. Experimental setup consisted of a multitone generator, two loudspeakers, human head model, intensimetric probe, the Cartesian robot applied for precise positioning of the acoustic sensor, and an analyzer. Based...
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When Biobanks Meet Religion: Association Between Religiosity and Attitudes of Polish Medical Students Toward Biobanking of Human Biological Material for Research Purposes
PublikacjaWhile biobanking is expanding globally, the empirical evidence concerning the impact of religion on future healthcare professionals’ awareness and willingness to donate biospecimens for biobank research is lacking. To understand how medicalstudents’ religious beliefs can fuel their questions regarding how biospecimens would be stored, cared for, and used, we conducted a survey among 1500 medical students at Poznań University...
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Determination of cytotoxic activity of new bisacridines IKE18, IKE19, IKE21 and IE10 against human kidney HEK-293 (ATCC® CRL-1573™) and liver cells HEPG2 (ATCC® HB-8065™)
Dane BadawczeThe datasets contain the results of determining in vitro cytotoxic activity of compounds using human cell lines assessed by 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) assay, a method that evaluates cell viability by measuring cellular oxidoreductase activity. Initially, cells were seeded in 96-well culture plates and allowed...
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Induction of G2/M phase arrest and apoptosis of human pancreatic cancer BxPC-3 cells by potenet antitumor 1-nitroacridine derivative C-1748
PublikacjaPancreatic ductal adenocarcinoma (PDA) is among the most lethal human cancers, in part because it is insensitive to many chemotherapeutic drugs. Gemcitabine still remains the best chemotherapeutic agent available for the treatment of advanced pancreatic cancer. However, gemcitabine treatment results in only a marginal survival advantage. Thus, there is a strong need for the continuous development of novel therapeutic agents...
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Human poverty - measuring relative deprivation from basic achievements: a comparative study for 144 countries over the period 1990-2010
PublikacjaPoverty – differently defined and measured – still remains one the crucial parts of the world development debate. It`s broadly perceived as multidimensional phenomenon which deprives people from basic capabilities and freedoms, limits their opportunity to educate and fully participate in the labor market contributing to overall country`s socioeconomic performance. Referring to seminal works of Sen and many others(see e.g. Morris...
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Asia Pacific Journal of Human Resources
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BMC International Health and Human Rights
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Human Gene Therapy Clinical Development
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Environmental Hazards-Human and Policy Dimensions
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IEEE Transactions on Human-Machine Systems
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Journal of Human Behavior in the Social Environment
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Journal of Gynecology Obstetrics and Human Reproduction
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South African Journal on Human Rights
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Journal of Chinese Human Resources Management
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Human-centric Computing and Information Sciences
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International Journal of Technology and Human Interaction
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Human Resource Management International Digest
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ACM Transactions on Computer-Human Interaction
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HOMO-JOURNAL OF COMPARATIVE HUMAN BIOLOGY
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Foundations and Trends in Human-Computer Interaction
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Sur - International Journal of Human Rights
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Journal of Human Rights and Social Work
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Journal of Health and Human Services Administration
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International Journal of Human Factors and Ergonomics
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INTERNATIONAL JOURNAL OF HUMAN-COMPUTER INTERACTION
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Muslim World Journal of Human Rights
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INTERNATIONAL JOURNAL OF HUMAN RESOURCE MANAGEMENT
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International Human Rights Law Review
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SA Journal of Human Resource Management
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Journal of Human Resources in Hospitality and Tourism
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HUMAN NATURE-AN INTERDISCIPLINARY BIOSOCIAL PERSPECTIVE
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INTERNATIONAL JOURNAL OF AGING & HUMAN DEVELOPMENT
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Egyptian Journal of Medical Human Genetics
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International Journal on Disability and Human Development
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European Human Rights Law Review
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International Journal on Disability and Human Development
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African Human Rights Law Journal
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ACM Transactions on Human-Robot Interaction
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Annual Review of Genomics and Human Genetics
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Proceedings of the ACM on Human-Computer Interaction
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ORGANIZATIONAL BEHAVIOR AND HUMAN DECISION PROCESSES
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Journal of Mental Health and Human Behaviour
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INTERNATIONAL JOURNAL OF HUMAN-COMPUTER STUDIES
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FILOLOGJIA International Journal of Human Sciences
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Journal of Southeast Asian Human Rights
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