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Wyniki wyszukiwania dla: anti-tumour imidazoacridinone
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Rapana thomasiana hemocyanin modified with ionic liquids with enhanced anti breast cancer activity
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The Action Mechanisms, Anti-Cancer and Antibiotic-Modulation Potential of Vaccinium myrtillus L. Extract
PublikacjaHerbal medicinal products containing Vaccinium myrtillus L. (bilberry) fruits and fruit extracts are widely available in the market. Although bilberry leaves and stems are considered as bio-waste, they contain much higher levels of phenolic compounds than fruits. The study aimed to investigate the antimicrobial and anticancer potential of aerial part extracts from Vaccinium myrtillus L. (V. myrtillus, VM) plants harvested at high...
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Evaluation of the anti-tyrosinase activity of extracts and rare flavonoids from Scleranthus perennis L.
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In vitro antioxidant, anti-inflammatory activities and acetylcholinesterase inhibition properties of selected plant extracts
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Determination of anti-tyrosinase activity of acetone extracts from selected Potentilla L. species.
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Anti-cancer effect of Rumex obtusifolius in combination with arginase/nitric oxide synthase inhibitors via downregulation of oxidative stress, inflammation, and polyamine synthesis
PublikacjaCancer continues to be a leading cause of death worldwide, making the development of new treatment methods crucial in the fight against it. With cancer incidence rates increasing worldwide, ongoing research must focus on identifying new and effective ways to prevent and treat the disease. The combination of herbal extracts with chemotherapeutic agents has gained much interest as a novel strategy to combat cancer. Rumex obtusifolius...
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Imidazoacridinone derivative C-1311 (SymadexTM) induces apoptosis, mitotic catastrophe or senescence in human colon carcinoma HCT116 cells depending on p53 status
PublikacjaPrzeprowadziliśmy badania zmierzające do wyjaśnienia odpowiedzi komórek ludzkiego raka jelita grubego HCT116 traktowanych C-1311 w zależności od statusu białka p53. Wykazaliśmy, że pochodna imidazoakrydonu C-1311 w stężeniach biologicznie istotnych indukuje przejściowy blok w fazie G2M komórek HCT116 p53-/- oraz blok w fazie G1 i G2M komórek HCT116 p53+/+. W komórkach z niefunkcjonalnym białkiem p53 imidazoakrydon indukował katastrofę...
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Compression and Fatigue Testing of High-Strength Thin Metal Sheets by Using an Anti-Buckling Device
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Simultaneous determination of non-steroidal anti-inflammatory drugs and oestrogenic hormones in environmental solid samples
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Anti-inflammatory drugs in the Vistula River following the failure of the Warsaw sewage collection system in 2019
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A novel green one-step synthesis of gold nanoparticles using crocin and their anti-cancer activities
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Tuning of the Anti-Breast Cancer Activity of Betulinic Acid via Its Conversion to Ionic Liquids
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In Vitro Screening for Anti-Acetylcholinesterase and Antioxidant Activities of Hottonia palustris L. Extracts and Their Unusual Flavonoids
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Effect of Functionalization of Reduced Graphene Oxide Coatings with Nitrogen and Sulfur Groups on Their Anti-Corrosion Properties
PublikacjaElectrophoretic production of anticorrosion carbonaceous coatings on copper could be successfully performed by anodic oxidation of negatively charged graphene platelets suspended in an aqueous solution. The various platelets were synthesized by Hummer’s method followed by a hydrothermal reduction in the presence of NH4SCN which was expected to substitute some parts of graphene structure with nitrogen and sulfur groups. X-ray photoelectron...
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Nonsteroidal anti-inflammatory drugs modulate cellular glycosaminoglycan synthesis by affecting EGFR and PI3K signaling pathways
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Investigation on the effect of anti-pitch fins for reducing the motion and acceleration of ships using computational fluid dynamics
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Inhibitors and Antibody Fragments as Potential Anti-Inflammatory Therapeutics Targeting Neutrophil Proteinase 3 in Human Disease
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Simultaneous determination of non-steroidal anti-inflammatory drugs and natural estrogens in the mussels Mytilus edulis trossulus
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DNA strand breaks induced by nuclear hijacking of neuronal NOS as an anti-cancer effect of 2-methoxyestradiol
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Assessment of Ocimum basilicum Essential Oil Anti-Insect Activity and Antimicrobial Protection in Fruit and Vegetable Quality
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Tribological Anti-Wear and Extreme-Pressure Performance of Multifunctional Metal and Nonmetal Doped C-based Nanodots
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Pharmacomicrobiomics of cell-cycle specific anti-cancer drugs – is it a new perspective for personalized treatment of cancer patients?
PublikacjaIntestinal bacteria are equipped with an enzyme apparatus that is involved in the active biotrans-formation of xenobiotics, including drugs. Pharmacomicrobiomics, a new area of pharmacology, analyses interactions between bacteria and xenobiotics. However, there is another side to the coin. Pharmacotherapeutic agents can significantly modify the microbiota, which consequently affects their efficacy. In this review, we comprehensively...
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In vitro antioxidant and anti-inflammatory activities of extracts from Potentilla recta and its main ellagitannin, agrimoniin
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Removal of nonsteroidal anti-inflammatory drugs and analgesics from wastewater by adsorption on cross-linked β-cyclodextrin
PublikacjaWe present a method using the material in the form of cross-linked β-cyclodextrin (CD) showing high efficiency in the simultaneous removal of hazardous pollutants from sewage, such as diclofenac (DIC), ibuprofen (IBU), ketoprofen (KETO), naproxen (NAPR), salicylic acid (SALI) and tramadol (TRAM). The material is stable and particularly easy to regenerate. The sorbent probably remembers the shape of the contaminants, which increases...
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Design of new cholinesterase inhibitors based on phosphorus analogs of tacrine as potential anti-Alzheimer’s disease agents
PublikacjaBased on the analysis of the determined free binding energy (using the AutoDock Vina 1.1.2 docking program), the most potent cholinesterase inhibitors were selected. Moreover, studies of 3D visualization of the results of molecular modeling led to the identification of potential sites for the interaction of new potential inhibitors with amino acid residues building active sites of investigated cholinesterases.
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Burkitt's tumour - Female, 6 - Tissue image [10060730015617891]
Dane BadawczeThis is the histopathological image of TONSIL tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.
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Burkitt's tumour - Female, 6 - Tissue image [10060730015614021]
Dane BadawczeThis is the histopathological image of TONSIL tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.
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Burkitt's tumour - Female, 6 - Tissue image [10060730015611561]
Dane BadawczeThis is the histopathological image of TONSIL tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.
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Burkitt's tumour - Female, 6 - Tissue image [10060730015613731]
Dane BadawczeThis is the histopathological image of TONSIL tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.
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Burkitt's tumour - Female, 6 - Tissue image [10060730015618171]
Dane BadawczeThis is the histopathological image of TONSIL tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.
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Burkitt's tumour - Female, 6 - Tissue image [10060730015614311]
Dane BadawczeThis is the histopathological image of TONSIL tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.
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Burkitt's tumour - Female, 6 - Tissue image [10060730015612021]
Dane BadawczeThis is the histopathological image of TONSIL tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.
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Burkitt's tumour - Female, 6 - Tissue image [1006073001561941]
Dane BadawczeThis is the histopathological image of TONSIL tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.
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Burkitt's tumour - Female, 6 - Tissue image [10060730015613821]
Dane BadawczeThis is the histopathological image of TONSIL tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.
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Burkitt's tumour - Female, 6 - Tissue image [1006073001561811]
Dane BadawczeThis is the histopathological image of TONSIL tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.
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Burkitt's tumour - Female, 6 - Tissue image [10060730015616221]
Dane BadawczeThis is the histopathological image of TONSIL tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.
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Burkitt's tumour - Female, 6 - Tissue image [10060730015615541]
Dane BadawczeThis is the histopathological image of TONSIL tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.
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Burkitt's tumour - Female, 6 - Tissue image [10060730015617621]
Dane BadawczeThis is the histopathological image of TONSIL tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.
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Burkitt's tumour - Female, 6 - Tissue image [10060730015616131]
Dane BadawczeThis is the histopathological image of TONSIL tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.
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Burkitt's tumour - Female, 6 - Tissue image [1006073001561631]
Dane BadawczeThis is the histopathological image of TONSIL tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.
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Analysis of cellular response induced by imidazoacridinone derivative C-1311 in Chinese hamster ovary carcinoma cells CHO with vorious expression level of cytochrome P450 reductase
PublikacjaRodzaj odpowiedzi komórkowej indukowanej przez pochodną C-1311 badany był w komórkach CHO o różnym poziomie reduktazy cytochromu P450. Wszystkie eksperymenty zostały przeprowadzone przy zastosowaniu stężenia związku odpowiadającego dawce EC80. Poziom ekspresji reduktazy cytochromu P450 nie miał istotnego wpływu na rodzaj odpowiedzi komórkowej indukowanej przez pochodną C-1311. Głównym efektem biologicznym wywieranym przez badany...
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Anti-Helicobacter pylori activities of selected N-substituted cinnamamide derivatives evaluated on reference and clinical bacterial strains
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Model yeast as a versatile tool to examine the antioxidant and anti-ageing potential of flavonoids, extracted from medicinal plants
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Yeast as a model to analyse the oxidative stress against acetic acid and anti-aging potential of Rice Flavonoids proceeding
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Bacterial Nanocellulose Fortified with Antimicrobial and Anti-Inflammatory Natural Products from Chelidonium majus Plant Cell Cultures
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Chemical Composition, Antioxidant, In Vitro and In Situ Antimicrobial, Antibiofilm, and Anti-Insect Activity of Cedar atlantica Essential Oil
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Application of g-C3N4/ZnO nanocomposites for fabrication of anti-fouling polymer membranes with dye and protein rejection superiority
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Divulging the anti-acetylcholinesterase activity of Colletotrichum lentis strain KU1 extract as sustainable AChE active site inhibitors
PublikacjaAlzheimer’s disease (AD), also called senile dementia is a neurodegenerative disease seen commonly in the elderly and is characterised by the formation of β-amyloid plaques and neurofbrillary tangles (NFT). Though a complete understanding of the disease is lacking, recent studies showed the role of the enzyme acetylcholinesterase (AChE) in pathogenesis. Finding new lead compounds from natural sources has always been a quest for...
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Application of g-C3N4/ZnO nanocomposites for fabrication of anti-fouling polymer membranes with dye and protein rejection superiority
PublikacjaPolysulfone (PSf) membranes are privileged for water and wastewater treatment, but because of their hydrophobic nature, they suffer from fouling, which lowers their performance and lifetime. In this work, g-C3N4 and g-C3N4/ZnO nanomaterials were synthesized via a hydrothermal method to modify the PSf membrane for effective dye separation and reduction of organic fouling. Since g-C3N4/ZnO possesses –OH and –NH reactive groups, g-C3N4/ZnO/PSf...
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Investigation on structural, optical and anti-bacterial properties of organic additives iron oxide prepared by chemical route method
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