Wyszukiwarka
Filtry
wszystkich: 444
-
Katalog
Wyniki wyszukiwania dla: molecular biology
-
Ultrastructural variability of macrophages in the wall of selected aorto-coronary bypass grafts
Publikacja -
Genes regulating programmed cell death are significantly upregulated in porcine immature oocytes
Publikacja -
Genes regulating biochemical pathways of oxygen metabolism in porcine oviductal epithelial cells during long-term IVC
Publikacja -
Protein oligomerization is the biochemical process highly up-regulated in porcine oocytes before in vitro maturation (IVM)
Publikacja -
Genes encoding proteins regulating fatty acid metabolism and cellular response to lipids are differentially expressed in porcine luminal epithelium during long-term culture
Publikacja -
Analysis of expression of genes responsible for regulation of cellular proliferation and migration – microarray approach based on porcine oocyte model
Publikacja -
Epithelium morphogenesis and oviduct development are regulated by significant increase of expression of genes after long-term in vitro primary culture – a microarray assays
Publikacja -
Pathogenesis and pathophysiology of ovarian follicular cysts in mammals
Publikacja -
Fatty Acids Related Genes Expression Undergo Substantial Changes in Porcine Oviductal Epithelial Cells During Long-Term Primary Culture
Publikacja -
Modeling the photodynamic effect in 2D versus 3D cell culture under normoxic and hypoxic conditions
Publikacja -
Aryl- and heteroaryl-substituted phenylalanines as AMPA receptor ligands
Publikacja -
Investigating the disease‐modifying properties of sclerotiorin in Alzheimer's therapy using acetylcholinesterase inhibition
Publikacja -
Current state of a dual behaviour of antimicrobial peptides-Therapeutic agents and promising delivery vectors
Publikacja -
Computational techniques for efficient conformational sampling of proteins
Publikacja -
Highly Potent Antidiuretic Antagonists: Conformational Studies of Vasopressin Analogues Modified with 1-Naphthylalanine Enantiomers at Position 2
Publikacja -
Influence of some anthropometric parameters on the risk of development of distal complications after mastectomy carried out because of breast carcinoma
Publikacja -
Structure–activity relationships study on biological activity of peptides as dipeptidyl peptidase IV inhibitors by chemometric modeling
Publikacja -
Genetic variability and differentiation of wild and cultured tench populations inferred from microsatellite loci
Publikacja -
Increased Interstitial Protein Because of Impaired Lymph Drainage Does Not Induce Fibrosis and Inflammation in Lymphedema
Publikacja -
Lymphangiogenesis Facilitates Initial Lymph Formation and Enhances the Dendritic Cell Mobilizing Chemokine CCL21 Without Affecting Migration
Publikacja -
The role of environmental optimization for storing bulls’ sperm cells
Publikacja -
The expression and intranuclear distribution of nucleolin in HL-60 and K-562 cells after repeated, short-term exposition to rotating magnetic fields
Publikacja -
COMPUTER-AIDED DESIGN OF ORGANOPHOSPHORUS INHIBITORS OF UREASE
PublikacjaBased on the structure of the most potential inhibitor diamidophosphate, various novel groups of inhibitors were developed by knowledge-based design approach with covalent carbon-phosphorus or carbon-phosphorus-carbon bond to improve hydrolytic stability to inhibit the microbial ureases. Designed compounds were evaluated with 10 (LigScore1, LigScore2, PLP1, PLP2, JAIN, PMF, PMF04, LUDI_1, LUDI_2 and LUDI_3) different scoring functions...
-
The comparison of antioxidant properties and nutrigenomic redox-related activities of vitamin C, C-vitamers, and other common ascorbic acid derivatives
PublikacjaThe term ‘vitamin C’ describes a group of compounds with antiscorbutic activity of L-ascorbic acid (AA). Despite AA’s omnipresence in plant-derived foods, its derivatives have also been successfully implemented in the food industry as antioxidants, including the D-isomers, which lack vitamin C activity. This study aimed to determine the relationship between redox-related activities for five derivatives of AA using electrochemical,...
-
Synthesis and biological evaluation of fluorinated 3-phenylcoumarin-7-O-sulfamate derivatives as steroid sulfatase inhibitors
PublikacjaIn the present work, we report the initial results of our study on a series of 3-phenylcoumarin sulfamate-based compounds containing C-F bonds as a novel inhibitors of steroid sulfatase (STS). The new compounds are potent STS inhibitors, possessing more than 10 times higher inhibitory potency than coumarin-7-O-sulfamate. In the course of our investigation, compounds 2b and 2c demonstrated the highest inhibitory effect in the enzymatic...
-
Structural Factors Affecting Cytotoxic Activity of (E)-1-(Benzo[d ][1,3]oxathiol-6-yl)-3-phenylprop-2-en-1-one Derivatives
PublikacjaDerivatives of (E)-1-(5-alkoxybenzo[d][1,3]oxathiol-6-yl)-3-phenylprop-2-en-1-one (1) demonstrated exceptionally high in vitro cytotoxic activity, with IC50 values of the most active derivatives in the nanomolar range. To identify structural fragments necessary for the activity, several analogs deprived of selected fragments were prepared, and their cytotoxic activity was tested. It was found that the activity depends on combined effects...
-
Coupling of Blood Pressure and Subarachnoid Space Oscillations at Cardiac Frequency Evoked by Handgrip and Cold Tests: A Bispectral Analysis
PublikacjaThe aim of the study was to assess blood pressure–subarachnoid space (BP–SAS) width coupling properties using time–frequency bispectral analysis based on wavelet transforms during handgrip and cold tests. The experiments were performed on a group of 16 healthy subjects (F/M; 7/9) of the mean age 27.2 ± 6.8 years and body mass index of 23.8 ± 4.1 kg/m². The sequence of challenges was first handgrip and then cold test. The handgrip...
-
Phylogenetic trees of genus Oncidium Sw. based on analysis of DNA sequences
Dane BadawczeGenus Oncidium Sw. is widely regarded as a polyphiletic, and the taxonomic boundaries between him and such genera as Odontoglossum Kunth. or Miltonia Lindley remain blurred. The goal of the study was to determine the phylogenetic relationships within the genus Oncidium s.lato based on the DNA sequences analysis. The correlation between molecular data...
-
E-egzamin - analiza statystyczna wyników
PublikacjaDnia 4 marca 2008 roku, po raz pierwszy w Polsce, odbył się próbny egzamin gimnazjalny z części matematyczno-przyrodniczej, przeprowadzany drogą elektroniczną, ''E-egzamin 2008''. Organizatorami egzaminu byli: Wyższa Szkoła Humanistyczno-Ekonomiczna i WSiP. Patronat nad projektem objęli: Minister EN i dyrektor Centralnej Komisji Egzaminacyjnej. Nietypowy próbny egzamin gimnazjalny pisało w jednym czasie kilka tysięcy gimnazjalistów...
-
The value of less Light – Sustainable architectural lighting design
PublikacjaSince its beginning, the art of external illumination has substantially influ-enced the creation and the perception of architecture and the night-time urban environment. In her lecture, the author examines and defines the significant interdisciplinary conditions related to architectural lighting design that have evolved over the years, starting from the first simple exterior lighting projects to the more modern, complex concepts...
-
A Computationally Efficient Model for Predicting Successful Memory Encoding Using Machine-Learning-based EEG Channel Selection
PublikacjaComputational cost is an important consideration for memory encoding prediction models that use data from dozens of implanted electrodes. We propose a method to reduce computational expense by selecting a subset of all the electrodes to build the prediction model. The electrodes were selected based on their likelihood of measuring brain activity useful for predicting memory encoding better than chance (in terms of AUC). A logistic...
-
Species differences in total mercury concentration in gulls from the Gulf of Gdansk (Southern Baltic)
Publikacja -
Forster energy transfer from nonexponentially decaying donors
PublikacjaPrzedyskutowano niezbędne modyfikacje stałej szybkości transferu foersterowskiego w sytuacji, kiedy zanik fluorescencji donora w nieobecności akceptora jest nieeksponencjalny. Stwierdzono, że najbardziej przydatna modyfikacja wynika założenia jednakowej wartości stałej zaniku radiacyjego dla wszystkich molekuł donora.
-
Benthic fluxes of oxygen and nutrients under the influence of macrobenthic fauna on the periphery of the intermittently hypoxic zone in the Baltic Sea
Publikacja -
The extracts from Panax quinquefolium shoots derived from somatic embryos accumulate ginsenosides and have the antioxidant properties
Publikacja -
Bactericidal effect of photodynamic inactivation against methicillin-resistant and methicillin-susceptible Staphylococcus aureus is strain-dependent
Publikacja -
The agr function and polymorphism: Impact on Staphylococcus aureus susceptibility to photoinactivation
Publikacja -
Room temperature solvent extraction for simple and fast determination of total concentration of Ca, Cu, Fe, Mg, Mn, and Zn in bee pollen by FAAS along with assessment of the bioaccessible fraction of these elements using in vitro gastrointestinal digestion
Publikacja -
Preparation and characterization of new zinc(II) phthalocyanine — Containing poly(l-lactide)-b-poly(ethylene glycol) copolymer micelles for photodynamic therapy
Publikacja -
Effect of xanthophyll pigments on fluorescence of chlorophyll a in LHC II embedded to liposomes
Publikacja -
Substantial decrease of urinary 8-oxo-7,8-dihydroguanine, a product of the base excision repair pathway, in DNA glycosylase defective mice
Publikacja -
Protochlorophyll complexes with similar steady-state fluorescence characteristics can differ in fluorescence lifetimes. A model study in Triton X-100
Publikacja -
Inhibition of ALDH1A1 activity decreases expression of drug transporters and reduces chemotherapy resistance in ovarian cancer cell lines
Publikacja -
The chitosan – Porphyrazine hybrid materials and their photochemical properties
Publikacja -
Photodynamic inactivation of Enterococcus faecalis by non-peripherally substituted magnesium phthalocyanines entrapped in lipid vesicles
Publikacja -
Tribenzoporphyrazines with dendrimeric peripheral substituents and their promising photocytotoxic activity against Staphylococcus aureus
Publikacja -
In vitro photodynamic activity of lipid vesicles with zinc phthalocyanine derivative against Enterococcus faecalis
Publikacja -
Effect of thienyl units in cyanoacrylic acid derivatives toward dye-sensitized solar cells
Publikacja -
The influence of the place of residence, smoking and alcohol consumption on bone mineral content in the facial skeleton
Publikacja -
Zespół Imerslund-Gräsbecka - rzadka choroba genetyczna różnych ras psów
Publikacja