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Wyniki wyszukiwania dla: BIOMARKER
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Biomarker Research
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Biomarker Insights
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Current Biomarker Findings
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Serum YKL-40 as a potential biomarker of inflammation in psoriasis
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Salivary Xanthine Oxidase as a Potential Biomarker in Stroke Diagnostics
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Serum mass profile signature as a biomarker of early lung cancer
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Circulating suPAR as a biomarker of disease severity in children with proteinuric glomerulonephritis
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RAGE as a Novel Biomarker for Prostate Cancer: A Systematic Review and Meta-Analysis
PublikacjaThe receptor for advanced glycation end-products (RAGE) has been implicated in driving prostate cancer (PCa) growth, aggression, and metastasis through the fueling of chronic inflammation in the tumor microenvironment. This systematic review and meta-analysis summarizes and analyzes the current clinical and preclinical data to provide insight into the relationships among RAGE levels and PCa, cancer grade, and molecular effects....
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Human hair as a biomarker of human exposure to persistent organic pollutants (POPs)
PublikacjaThe main aim of this article is to investigate the possibility of using human hair as a biomarker with particular emphasis on persistent organic pollutants (POPs). We report previous results of studies of this topic. We critically review the available information on analytical procedures applied during analysis of human hair. Finally, we discuss future trends and possibilities arising from hair analysis.
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Survivin DEx3 as a biomarker of thyroid cancers: A study at the mRNA and protein level
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Deep Data Analysis of a Large Microarray Collection for Leukemia Biomarker Identification
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Partial characterization of proteins from mussel Mytilus galloprovincialis as a biomarker of contamination
PublikacjaPrzedmiotem zainteresowania były:- funkcjonalne i przeciwutleniające właściwości białek małża Mytilus galloprovincialis,- poziom zawartości metali ciężkich (ołów i kadm) w tkankach.Badania przeprowadzono dla małży zebranych zarówno w zanieczyszczonych, jak i w czystych obszarach strefy brzegowej Morza Czarnego w regionie Warny (Bułgaria). W badaniach wykorzystano takie techniki analityczne jak: spektroskopia FTIR, fluorescencja,...
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Total DNA methylation as a biomarker of DNA damage and tumor malignancy in intracranial meningiomas
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Advanced Assessment of the Endogenous Hormone Level as a Potential Biomarker of the Urogenital Tract Cancer
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Determination of thiocyanate as a biomarker of tobacco smoke constituents in selected biological materials of human origin
Publikacjan order to protect human health, it is necessary to biomonitor toxic substances originating from tobacco smoke in biological materials sampled from persons with different exposures to tobacco smoke constituents. Thiocyanate anion is a biomarker of exposure to tobacco smoke components which is characterized by a relatively long half‐life in the human body, i.e. 6 days. In this work, we present the results of thiocyanate determinations...
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imPlatelet classifier: image‐converted RNA biomarker profiles enable blood‐based cancer diagnostics
PublikacjaLiquid biopsies offer a minimally invasive sample collection, outperforming traditional biopsies employed for cancer evaluation. The widely used material is blood, which is the source of tumor-educated platelets. Here, we developed the imPlatelet classifier, which converts RNA-sequenced platelet data into images in which each pixel corresponds to the expression level of a certain gene. Biological knowledge from the Kyoto Encyclopedia...
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Serum miRNA-based signature indicates radiation exposure and dose in humans: a multicenter diagnostic biomarker study
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Serum miRNA-based signature indicates radiation exposure and dose in humans: A multicenter diagnostic biomarker study
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Novel electrogravimetric biosensors for the ultrasensitive detection of plasma matrix metalloproteinase-2 considered a potential tumor biomarker
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Ultrasensitive electrochemical determination of the cancer biomarker protein sPD-L1 based on a BMS-8-modified gold electrode
PublikacjaThis work describes the modification of a gold electrode with the BMS-8 compound that interacts with the Programmed Death-Ligand 1 (PD-L1), an immune checkpoint protein. The results show that we can confirm the presence of the sPD-L1 in the concentration range of 10−18 to 10−8 M using electrochemical impedance spectroscopy (EIS) with a limit of detection (LOD) of 1.87 × 10−14 M for PD-L1 (S/N = 3.3) and at a concentration of 10−14...
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The Osteopontin Tissue Level as a Breast Cancer Biomarker in Females After Mastectomy Measured by the Capillary Gel Electrophoresis Technique
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Galectin-3 as a Novel Multifaceted and Not Only Cardiovascular Biomarker in Patients with Psoriasis with Regard to Systemic Treatment—Preliminary Data
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Toward consensus in the analysis of urinary 8‐oxo‐7,8‐dihydro‐2′‐deoxyguanosine as a noninvasive biomarker of oxidative stress
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Plasma free amino acid profiling as metabolomic diagnostic and prognostic biomarker in paediatric cancer patients: a follow‑up study
PublikacjaAmino acids (AAs) play a crucial role in cancer cell metabolism. Levels of 22 plasma AAs at the time of diagnosis and after treatment were established among 39 pediatric cancer patients and 33 healthy children. Glutamic acid levels decreased and tryptophan levels increased during treatment. Cancer patients presented significantly lower levels of glutamine and leucine post-treatment while levels of 12 other AAs were higher comparing...
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Correction to: Plasma free amino acid profiling as metabolomic diagnostic and prognostic biomarker in paediatric cancer patients: a follow-up study
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Coincidence of PTPN22 c.1858CC and FCRL3 -169CC genotypes as a biomarker of preserved residual β-cell function in children with type 1 diabetes
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Enzymatic cleavage of specific dipeptide conjugated with ferrocene as a flexible ultra-sensitive and fast voltammetric assay of matrix metalloproteinase-9 considered a prognostic cancer biomarker in plasma samples
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Cadmium Phytotoxicity—Biomarkers
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Cancer Biomarkers
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Current Biomarkers
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Journal of Biomarkers
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Biomarkers in Neuropsychiatry
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Digital Biomarkers
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System do kondensacji wydychanego powietrza przy wykrywaniu biomarkerów chorób układu oddechowego
PublikacjaPraca opisuje konstrukcję oraz testy urządzenia zbierającego skropliny wydychanego powietrza, w których znadują się biomarkery chorób układu oddechowego. Celem urządzenia jest zwiększenie koncentracji biomarkerów, które mogą być następnie wykrywane za pomocą przygotowanego spektrofotometru i pH-metru. W pracy przedstawiono szczegółowo konstrukcję oraz sposób analizy zbieranych próbek. Skuteczność działania urządzenia przetestowano...
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System do kondensacji wydychanego powietrza przy wykrywaniu biomarkerów chorób układu oddechowego
PublikacjaPraca opisuje konstrukcję oraz testy urządzenia zbierającego skropliny wydychanego powietrza, w których znadują się biomarkery chorób układu oddechowego. Celem urządzenia jest zwiększenie koncentracji biomarkerów, które mogą być następnie wykrywane za pomocą przygotowanego spektrofotometru i pH-metru. W pracy przedstawiono szczegółowo konstrukcję oraz sposób analizy zbieranych próbek. Skuteczność działania urządzenia przetestowano...
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BIOMARKERS
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Journal of Circulating Biomarkers
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Open Biomarkers Journal
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MicroRNAs as efficient biomarkers in high-grade gliomas
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The occurence and diagnosis of biomarkers of ethyl alcohol consumption
PublikacjaEthyl alcohol is a legal and a widely available psychoactive drug. However, its excessive consumption causes addiction. This leads to aggressive behaviors, family battery, difficulties in interpersonal relations, legal offences, suicides, car accidents and deterioration in labor productivity, what causes financial problems. Despite many social actions against alcohol consumption, this problem is still unresolved. Therefore, fast...
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Molecularly imprinted polymers for the detection of volatile biomarkers
PublikacjaIn the field of cancer detection, the development of affordable, quick, and user-friendly sensors capable of detecting various cancer biomarkers, including those for lung cancer (LC), holds utmost significance. Sensors are expected to play a crucial role in the early-stage diagnosis of various diseases. Among the range of options, sensors emerge as particularly appealing for the diagnosis of various diseases, owing to their cost-effectiveness,...
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Oxidative stress in humans: validation of biomarkers of DNA damage
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2-Methoxyestradiol and Hydrogen Peroxide as Promising Biomarkers in Parkinson’s Disease
PublikacjaEstrogens function in numerous physiological processes including controlling brain cell growth and differentiation. 2-Meth- oxestradiol (2-ME2), a 17β-estradiol (E2) metabolite, is known for its anticancer effects as observed both in vivo and in vitro. 2-ME2 affects all actively dividing cells, including neurons. The study aimed to determine whether 2-ME2 is a potentially cancer-protective or rather neurodegenerative agent in a...
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Y2O3:Eu nanocrystals as biomarkers prepared by a microwave hydrothermal method
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Are advanced glycation end-products specific biomarkers for Alzheimer's disease?
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Extracellular miRNAs as Biomarkers of Head and Neck Cancer Progression and Metastasis
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Metabolic profiling of pteridines for determination of potential biomarkers in cancer diseases
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Genetic Testing and Molecular Biomarkers
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Circulating microRNAs as Biomarkers of Radiation Exposure: A Systematic Review and Meta-Analysis
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Isoprostanes-Biomarkers of Lipid Peroxidation: Their Utility in Evaluating Oxidative Stress and Analysis
PublikacjaIsoprostanes (IsoPs) are key biomarkers for investigating the role of free radical generation in the pathogenesis of human disorders. To solve IsoPs-related problems with regard to isoprostanes, analytical tools are required. This paper reviews the problems and trends in this field focusing on the methodology for assaying biomarkers in exhaled breath condensate (EBC) samples. A large amount of work has been done in the qualitative...