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Wyniki wyszukiwania dla: FATAL AND NONFATAL INTOXICATION
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Nonfatal and fatal intoxications with pure caffeine – report of three different cases
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Fatal N-Ethylhexedrone Intoxication
PublikacjaN-Ethylhexedrone [2-(ethyloamino)-1-phenylhexan-1-one; α-ethylaminohexanophenone; NEH] is one of the most recent synthetic cathinones that appeared on the illegal market in late 2015. The majority of information concerning the model of consumption of NEH and its impact on the body originates only from self-reports from grey literature websites and drug forums. There are only limited data associated with the concentrations of NEH...
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Fatal intoxication with hydrocarbons in deltamethrin preparation
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Fatal intoxication with N-ethylpentylone: a case report and method for determining N-ethylpentylone in biological material
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Fatal intoxication with U-47700 in combination with other NPS (N-ethylhexedrone, adinazolam, 4-CIC, 4-CMC) confirmed by identification and quantification in autopsy specimens and evidences
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Marijuana intoxication in a cat
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Fatal iatrogenic vinorelbine poisoning
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Antioxidant properties of black tea in alcohol intoxication
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HYPONATREMIA & WATER INTOXICATION WITH CARBAMAZEPINE: A RARE CASE REPORT.
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HYPONATREMIA & WATER INTOXICATION WITH CARBAMAZEPINE: A RARE CASE REPORT.
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Theophylline Therapy for Near-Fatal Cheyne–Stokes Respiration: A Case Report
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Oxidative Stress Level in the Testes of Mice and Rats during Nickel Intoxication
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Acute intranasal intoxication with mercuric chloride taken accidently instead of cocaine - A case report
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Fulminant hepatic failure in woman with iron and non-steroidal anti-inflammatory drug intoxication
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The case of fatal acute hemorrhagic necrotizing encephalitis in a two-month-old boy with Covid-19.
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The Assessment of Maternal and Fetal Intima-Media Thickness in Perinatology
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The methylome and transcriptome of fetal skin: implications for scarless healing
PublikacjaAim: Fetal skin is known to heal without scarring. In mice, the phenomenon is observed until the 16–17 day of gestation – the day of transition from scarless to normal healing. The study aims to identify key methylome and transcriptome changes following the transition. Materials & methods: Methylome and transcriptome profiles were analyzed in murine dorsal skin using microarray approach. Results & conclusion: The genes associated...
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Melatonin stimulates the activity of protective antioxidative enzymes in myocardial cells of rats in the course of doxorubicin intoxication
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The analysis of selected microelements in neonatal umbilical cord blood
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Fatal Case of Acute Cardiac Failure After Long-Term Physical Restraint of Patient Treated With Clozapine in Psychiatric Ward
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Fetal growth trajectory in type 1 pregestational diabetes (PGDM) — an ultrasound study
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Fatal sepsis in a pregnant woman with pyelonephritis caused by Escherichia coli bearing Dr and P adhesins: diagnosis based on postmortem strain genotyping
PublikacjaW pracy został opisany pierwszy śmiertelny przypadek młodej kobiety w ciąży z powodu przewlekłego zapalenia odmiedniczkowego nerek spowodowany przez szczepy E. coli z fimbriami typu Dr + i P. Badania pośmiertne wykazały, że śmierć nastąpiła z powodu posocznicy do której doszło na skutek zakażenia szczepami E. coli Dr + . Odmiedniczkowe zapalenie nerek w ciąży jest związane z wieloma powikłaniami, w tym ograniczeniem wzrostu płodu,...
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Platelets in fetal growth restriction: role of reactive oxygen species, oxygen metabolism, and aggregation.
PublikacjaFetal growth restriction (FGR) is mainly caused by failure of the uteroplacental unit. Theexact pathogenesis remains unclear. The cause is thought to be related to abnormal platelet activation,which may...
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Fetal Brain Imaging: A Composite Neural Network Approach for Keyframe Detection in Ultrasound Videos
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Changes in gene methylation patterns in neonatal murine hearts: Implications for the regenerative potential
PublikacjaBackground The neonatal murine heart is able to regenerate after severe injury; this capacity however, quickly diminishes and it is lost within the first week of life. DNA methylation is an epigenetic mechanism which plays a crucial role in development and gene expression regulation. Under investigation here are the changes in DNA methylation and gene expression patterns which accompany the loss of regenerative potential. Results The...
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Urinary Proteome of Newborn Calves—New Potential in Non-Invasive Neonatal Diagnostic
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Meconium analysis as a promising diagnostic tool for monitoring fetal exposure to toxic substances: Recent trends and perspectives
PublikacjaPrenatal exposure to toxic substances is an important public health problem. Many biological specimens obtained from the fetus or mother are used for biomonitoring. Each material reflects exposure in a specific time period and has different advantages and disadvantages in terms of accuracy, time window of detection and cost/benefit ratio. Recently, meconium has become the matrix of choice in toxicology screening for detecting exposure...
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Pharmaceutical care in the neonatal intensive care unit: Perspectives of Polish medical and pharmacy students
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Association between uridin diphosphate glucuronosylotranserase 1A1 (UGT1A1) gene polymorphism and neonatal hyperbilirubinemia
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Calcium, Potassium, Sodium, and Magnesium Concentrations in the Placenta, Umbilical Cord, and Fetal Membrane from Women with Multiple Pregnancies
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Transcriptome profiling reveals distinctive traits of retinol metabolism and neonatal parallels in the MRL/MpJ mouse
PublikacjaBackground: The MRL/MpJ mouse is a laboratory inbred strain known for regenerative abilities which are manifested by scarless closure of ear pinna punch holes. Enhanced healing responses have been reported in other organs. A remarkable feature of the strain is that the adult MRL/MpJ mouse retains several embryonic biochemical characteristics, including increased expression of stem cell markers. Results: We explored the transcriptome...
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Effect of Converting Enzyme Inhibitor on Copper and Iron Concentrations of Blood Plasma in Calves During the Neonatal Period
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Neonatal excitotoxic ventral hippocampal damage alters dopamine response to mild repeated stress and to chronic haloperidol
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Tribological Anti-Wear and Extreme-Pressure Performance of Multifunctional Metal and Nonmetal Doped C-based Nanodots
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Twenty‐four‐hour and conventional blood pressure components and risk of preterm delivery or neonatal complications in gestational hypertension
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Identification of novel psychoactive substances 25B-NBOMe and 4-CMC in biological material using HPLC-Q-TOF-MS and their quantification in blood using UPLC–MS/MS in case of severe intoxications
PublikacjaThis paper describes cases of poisoning caused by new psychoactive substances such as: 25BNBOMe (2-(4-bromo-2,5-dimethoxyphenyl)-N-[(2-methoxyphenyl)methyl]ethanamine) and 4-CMC (1-(4-chlorophenyl)-2-(methylamino)-1-propanone). The analytical procedure includes rapid and selective method for the extraction and determination of 4-CMC and 25B-NBOMe in blood samples using UPLC–MS/MS technique. To the best of our knowledge,this is...
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Application of gas chromatography–tandem mass spectrometry for the determination of amphetamine-type stimulants in blood and urine
PublikacjaAmphetamine, methamphetamine, phentermine, 3,4-methylenedioxyamphetamine (MDA), 3,4-methylenedioxymethamphetamine (MDMA), and 3,4-methylenedioxy-N-ethylamphetamine (MDEA) are the most popular amphetamine-type stimulants. The use of these substances is a serious societal problem worldwide. In this study, a method based on gas chromatography-tandem mass spectrometry (GC-MS/MS) with simple and rapid liquid-liquid extraction (LLE)...
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Extended-spectrum beta-lactamase-producing Klebsiella pneumoniae in a neonatal unit: control of an outbreak using a new ADSRRS technique
PublikacjaSzczepy Klebsiella pneumoniae (EPKP)produkujące beta-laktamazy o rozszerzonym spektrum substratowym (ESBL)stanowią często problem zakażeń na oddziałach noworodkowych. Izolaty od 149 pacjentów poddano typowaniu nową metodą opartą na zjawisku supresji PCR, ADSRRS-fingerprinting, wykazując pochodzenie klonalne badanych szczepów. Użyteczność techniki ADSRRS-finerprinting została potwierdzona innymi metodami - RAPD i PFGE.
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Blood concentrations of a new psychoactive substance 4-chloromethcathinone (4-CMC) determined in 15 forensic cases
PublikacjaPurpose: The 4-chloromethcathinone (4-CMC) is a synthetic derivative of cathinone and belongs to new psychoactive substances. Neither data on the effects of 4-CMC on the human body, nor on nontoxic, toxic and lethal concentrations in biological materials have been published in the literature. This paper describes the results of an analysis of the blood concentrations of 4-CMC determined in 15 forensic cases related to nonfatal...
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Neonatal ventral hippocampal damage modifies serum corticosterone and dopamine release responses to acute footshock in adult Sprague-Dawley rats
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Erratum to “The kinetics of phenol decomposition under UV irradiation with and without H2O2 on TiO2, Fe–TiO2 and Fe–C–TiO2 photocatalysts” [Appl. Catal. B: Environ. 65 (2006) 86–92]
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Development and validation of a method for the simultaneous analysis of fatty acid ethyl esters, ethyl sulfate and ethyl glucuronide in neonatal meconium: application in two cases of alcohol consumption during pregnancy
PublikacjaAlcohol consumption during pregnancy constitutes one of the leading preventable causes of birth defects and neurodevelopmental disorders in the exposed children. Fatty acid ethyl esters (FAEEs), ethyl glucuronide (EtG) and ethyl sulfate (EtS) have been studied as potential biomarkers of alcohol consumption. However, most analytical approaches proposed for their analysis in meconium samples consist of separated extraction procedures...
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Book Review: Vishwas Satgar (ed.), The Solidarity Economy Alternative: Emerging Theory and PracticeSatgarVishwas (ed.), The Solidarity Economy Alternative: Emerging Theory and Practice, University of KwaZulu-Natal Press: Durban, 2014; 332 pp.: ISBN 9781869142575, US$34.44
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Recent developments in biological sample testing methods for the confirmation of gestational exposure to tobacco smoke anddrugs of abused
PublikacjaSubstance use is most prevalent in reproductive-aged people also by women during pregnancy. In national prevalence surveys among women aged 15 to 44 years, 10.8 % of women reported using alcohol during pregnancy, 17 % reported smoking during pregnancy, and 4.4 % reported abusing any illicit substances during pregnancy. Virtually all illegal drugs, such as heroin and cocaine, pose dangers to a pregnant woman. Legal substances, such...
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Wrodzone zwężenie zastawki aortalnej - wyniki leczenia operacyjnego i interwencyjnego, z wykluczeniem krytycznej stenozy aortalnej noworodkowej = Congenitial aortic stenosis - outcomes after surgical treatment and baloon dilatation with exclusion of neonatal critical congenitial aortic stenosis
PublikacjaOdległe wyniki leczenia wrodzonego zwężenia zastawki aortalnej są ważnym problemem medycznym. Celem pracy była ocena wyników postępowania zabiegowego u dzieci z wrodzonym zwężeniem zastawki aortalnej.
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Determination of MDPBP in postmortem blood samples by gas chromatography coupled with mass spectrometry
PublikacjaMDPBP (1-(3,4-methylenedioxyphenyl)-2-(1-pyrrolidinyl)-1-butanone) is a new psychoactive substance sold on the black market. It has been a controlled drug of abuse in Poland and China since 2015 as some toxic and fatal cases connected with use of synthetic cathinone derivatives were observed. The fatal case outlined here concerns a 19 year-old man, who was found dead with an envelope containing white powder lying nearby the cadaver....
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Prenatal exposure to substance of abuse: A worldwide problem
PublikacjaSubstance abuse during pregnancy is an important public health issue affecting the mother and the growing infant. Preterm labor, miscarriage, abruption and postpartum hemorrhage are obstetric complications which have been associated with women who are dependent on abused substances. Moreover, women are also at an increased risk of medical problems such as poor nutrition, anemia, urinary tract infections as well as sexually transmitted...
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Insight into heart regeneration
PublikacjaThe mammalian heart is thought to be incapable of regeneration because of the limited ability of cardiomyocytes. to proliferate. However, it has been recently shown that the neonatal murine heart is able to restore its normal function after coronary artery ligation or even partial resection. Unfortunately, this feature is lost in a few days after birth, although lower vertebrates as zebrafish or newt, retain this ability until adulthood. Therefore,...
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Effects of Addictive Substances During Pregnancy and Infancy and Their Analysis in Biological Materials
PublikacjaThe use of addictive substances during pregnancy is a serious social problem, not only because of effects on the health of the woman and child, but also because drug or alcohol dependency it detracts from childcare and enhances the prospect of child neglect and family breakdown. Developing additive substance abuse treatment programs for pregnant women is socially important and can help ensure the health of babies, prevent subsequent...
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Designing digital displays and interactive media in today’s cities by night. Do we know enough about attracting attention to do so?
PublikacjaWith the huge transformation in the development of digital screen technology and its consistently decreasing cost, digital billboards are progressively replacing traditional static, two-dimensional poster advertisements in our cities1. Previously, due to the substantial expenditure involved, they were only available to major international brands with vast promotional resources to build their brand fame. Today, however, they are...