Filtry
wszystkich: 1402
-
Katalog
- Publikacje 1121 wyników po odfiltrowaniu
- Czasopisma 165 wyników po odfiltrowaniu
- Osoby 23 wyników po odfiltrowaniu
- Wynalazki 2 wyników po odfiltrowaniu
- Projekty 1 wyników po odfiltrowaniu
- Zespoły Badawcze 1 wyników po odfiltrowaniu
- Kursy Online 36 wyników po odfiltrowaniu
- Wydarzenia 13 wyników po odfiltrowaniu
- Dane Badawcze 40 wyników po odfiltrowaniu
wyświetlamy 1000 najlepszych wyników Pomoc
Wyniki wyszukiwania dla: EPIGENETIC DRUGS
-
A new silylating reagent – dimethyl(3,3,3-trifluoropropyl)silyldiethylamine – for the derivatisation of non-steroidal anti-inflammatory drugs prior to gas chromatography–mass spectrometry analysis
Publikacja -
Discovery of small-molecule regenerative drugs using a model of complex tissue injury in mice. Transcriptomic responses of neurodevelopmental genes during pharmacologically induced regeneration
PublikacjaDespite significant development in regenerative medicine, there is a deficit of effective therapies for wound healing and tissue regeneration. Research performed using animal wound models allows for a better understanding of this complex process, searching for compounds with pro-regenerative properties, and assessing their efficacy and safety. Unfortunately, the lack of adequate preclinical models proves to be an issue as no animal...
-
Theoretical Encapsulation of Fluorouracil (5-FU) Anti-Cancer Chemotherapy Drug into Carbon Nanotubes (CNT) and Boron Nitride Nanotubes (BNNT)
PublikacjaIntroduction: Chemotherapy with anti-cancer drugs is considered the most common approach for killing cancer cells in the human body. However, some barriers such as toxicity and side effects would limit its usage. In this regard, nano-based drug delivery systems have emerged as cost-effective and efficient for sustained and targeted drug delivery. Nanotubes such as carbon nanotubes (CNT) and boron nitride nanotubes (BNNT) are promising...
-
Silver Nanoparticles as Chlorhexidine and Metronidazole Drug Delivery Platforms: Their Potential Use in Treating Periodontitis
Publikacja -
ENCAPSULATION OF ROXITHROMYCIN INTO GELLAN GUM MATRICES AND THE IMPACT OF OTHER NATURAL POLYMERS ON DRUG RELEASE
Publikacja -
Drug-Releasing Antibacterial Coating Made from Nano-Hydroxyapatite Using the Sonocoating Method
Publikacja -
Elastic-contractile model proteins: Physical chemistry, protein function and drug design and delivery
Publikacja -
Drug transporter expression profiling in chemoresistant variants of the A2780 ovarian cancer cell line
Publikacja -
Microneedle‐Based Generation of Microbubbles in Cancer Tumors to Improve Ultrasound‐Assisted Drug Delivery
Publikacja -
Cisplatin filled multiwalled carbon nanotubes – a novel molecular hybrid of anticancer drug container
Publikacja -
Bioactive silica-based drug delivery systems containing doxorubicin hydrochloride: In vitro studies
Publikacja -
Use of Materials Based on Polymeric Silica as Bone-Targeted Drug Delivery Systems for Metronidazole
Publikacja -
Glucosamine-6-phosphate synthase,a novel target for antifungalagents.Molecular modelling studies in drug design
PublikacjaPraca dotyczy modelowania zarówno samych inhibitorów syntazy glukozamino-6-fosforanu jak i ich oddziaływania z obydwiema domenami tego enzymu. Enzym syntaza glukozamino-6-fosforanu został zaproponowany jako nowy cel molekularny w chemoterapii infekcji grzybowych. Zaprojektowano i zsyntezowano szereg inhibitorów tego enzymu - potencjalnych nowych leków przeciwgrzybowych. Dzięki modelowaniu molekularnemu udało się wyjaśnić mechanizm...
-
The modulatory effect of green tea catechin on drug resistance in human ovarian cancer cells
Publikacja -
Acinetobacter baumannii isolated from hospital‐acquired infection: biofilm production and drug susceptibility
Publikacja -
Fulminant hepatic failure in woman with iron and non-steroidal anti-inflammatory drug intoxication
Publikacja -
Bovine Serum Albumin – Hydroxyapatite Nanoflowers as Potential Local Drug Delivery System of Ciprofloxacin
PublikacjaIntroduction: Hybrid nanoflowers are structures consisting of organic (enzymes, proteins, nucleic acids) and inorganic components (mostly metal phosphates) with a flower-like hierarchical structure. Novel hybrid nanoflowers based on bovine serum albumin (BSA) and hydroxyapatite (HA) were obtained and characterized. Study on BSA-HA nanoflowers as potential drug delivery system is reported for the first time. Methods: Embedding ciprofloxacin...
-
New Life of an Old Drug: Caffeine as a Modulator of Antibacterial Activity of Commonly Used Antibiotics
Publikacja -
The Current Use of Mass Spectrometry in Combination with Other Separation Techniques in Drug Discovery Arena
Publikacja -
Drug-Eluting Biopsy Needle as a Novel Strategy for Antimicrobial Prophylaxis in Transrectal Prostate Biopsy
PublikacjaOBJECTIVES: To preclinically evaluate drug-eluting biopsy needles (patent pending WO2016118026) as a new potential way of antimicrobial prophylaxis for transrectal prostate biopsy. METHODS: Twenty steel biopsy needles have been coated with polyvinyl alcohol, ciprofloxacin, and amikacin. Modified biopsy needles have been randomly divided into 3 groups (1:2:1 ratio). Needles from group I were immersed for 30 minutes in dedicated...
-
Homoisocitrate dehydrogenase from Candida albicans: properties, inhibition, and targeting by an antifungal pro-drug
PublikacjaThe LYS12 gene from Candida albicans, coding for homoisocitrate dehydrogenase was cloned and expressed as a His-tagged protein in Escherichia coli. The purified gene product catalyzes the Mg2+- and K+-dependent oxidative decarboxylation of homoisocitrate to alpha-ketoadipate. The recombinant enzyme demonstrates strict specificity for homoisocitrate. SDS-PAGE of CaHIcDH revealed its molecular mass of 42.6±1 kDa, while in size-exclusion...
-
Nanosize effect of clay mineral nanoparticles on the drug diffusion processes in polyurethane nanocomposite hydrogels
PublikacjaStudies of swelling and release of naproxen sodium (NAP) solution by polyurethane nanocomposite hydrogels containing Cloisite® 30B (organically modified montmorillonite (OMMT)) have been performed. Polyurethane nanocomposite hydrogels are hybrid, nontoxic biomaterials with unique swelling and release properties in comparison with unmodified hydrogels. These features enable to use nanocomposite hydrogels as a modern wound dressing....
-
DRUGS OF THE FUTURE
Czasopisma -
Modeling of pharmaceuticals mixtures toxicity with deviation ratio and best-fit functions models
PublikacjaThe present study deals with assessment of ecotoxicological parameters of 9 drugs (diclofenac (sodium salt), oxytetracycline hydrochloride, fluoxetine hydrochloride, chloramphenicol, ketoprofen, progesterone, estrone, androstenedione and gemfibrozil), present in the environmental compartments at specific concentration levels, and theirmutual combinations by couples against Microtox® and XenoScreen YES/YAS® bioassays. As the quantitative...
-
Analiza modalna konstrukcji podpierającej stanowiska badawczego dynamiki małogabarytowych wirników część druga - badania symulacyjne
PublikacjaCelem niniejszej pracy było przedstawienie badań eksperymentalnych oraz symulacyjnych stanowiska VIBstand. W pracy przedstawiono dokładne wyniki badań symulacyjnych, oraz skrótowo wyniki badań eksperymentalnych w celu porównania wyników. Dokładne wyniki badań eksperymentalnych przedstawione zostały części pierwszej artykułu (Analiza modalna konstrukcji podpierającej stanowiska badawczego dynamiki małogabarytowych wirników. Część...
-
DRUG AND CHEMICAL TOXICOLOGY
Czasopisma -
DRUG METABOLISM AND DISPOSITION
Czasopisma -
DRUG DEVELOPMENT RESEARCH
Czasopisma -
DRUG METABOLISM REVIEWS
Czasopisma -
ASSAY AND DRUG DEVELOPMENT TECHNOLOGIES
Czasopisma -
ARZNEIMITTEL-FORSCHUNG-DRUG RESEARCH
Czasopisma -
CURRENT CANCER DRUG TARGETS
Czasopisma -
Expert Opinion On Drug Safety
Czasopisma -
American Health and Drug Benefits
Czasopisma -
Drug Delivery and Translational Research
Czasopisma -
Expert Opinion on Drug Delivery
Czasopisma -
Drug Design Development and Therapy
Czasopisma -
Journal of Drug Metabolism & Toxicology
Czasopisma -
International Journal of Drug Discovery
Czasopisma -
Expert Opinion on Drug Discovery
Czasopisma -
DRUG DEVELOPMENT AND INDUSTRIAL PHARMACY
Czasopisma -
FOOD AND DRUG LAW JOURNAL
Czasopisma -
Drug Healthcare and Patient Safety
Czasopisma -
Clinical Pharmacology in Drug Development
Czasopisma -
INTERNATIONAL JOURNAL OF DRUG POLICY
Czasopisma -
Journal of Drug Policy Analysis
Czasopisma -
Current drug abuse reviews
Czasopisma -
Infectious Disorders - Drug Targets
Czasopisma -
Journal of Nanopharmaceutics and Drug Delivery
Czasopisma -
Drug Discovery Today: Technologies
Czasopisma