Search
Filters
total: 434
filtered: 370
Search results for: MAGNESIUM POTASSIUM PHOSPHATE
-
Experimental and theoretical analyses of the nonlinear optical effects in magnesium and copper co-doped zinc oxide nanorods
Publication -
Multisine impedimetric monitoring with an in-depth distribution of relaxation times analysis of WE43 and AZ31 magnesium alloys corrosion
PublicationThis research aims to develop and utilize an impedance-based tool for monitoring non-stationary electrochemical processes, coupling the multisinusoidal perturbation signal approach and distribution of relaxation times (DRT) analysis for the first time. The approach was used to distinguish independent processes occurring at the surface of AZ31 and WE43 Mg alloys undergoing corrosion in Hank’s Balanced Salt Solution at 37 °C. We...
-
Two small RNAs conserved in Enterobacteriaceae provide intrinsic resistance to antibiotics targeting the cell wall biosynthesis enzyme glucosamine-6-phosphate synthase
PublicationFormation of glucosamine-6-phosphate GlcN6P) by enzyme GlcN6P synthase (GlmS) represents the first step in bacterial cell envelope synthesis. In Escherichia coli, expression of glmS is controlled by small RNAs (sRNAs) GlmY and GlmZ. GlmZ activates the glmS mRNA by base-pairing. When not required, GlmZ is bound by adapter protein RapZ and recruited to cleavage by RNase E inactivating the sRNA. The homologous sRNA GlmY activates...
-
Fluconazole resistant Candida auris clinical isolates have increased levels of cell wall chitin and increased susceptibility to a glucosamine-6-phosphate synthase inhibitor
PublicationIn 2009 Candida auris was first isolated as fungal pathogen of human disease from ear canal of a patient in Japan. In less than a decade, this pathogen has rapidly spread around the world and has now become a major health challenge that is of particular concern because many strains are resistant to multiple class of antifungal drugs. The lack of available antifungals and rapid increase of this fungal pathogen provides an incentive...
-
N-Alkylation of D-glucosamine and 2-amino-2-deoxy-D-glucitol-6-phosphate
PublicationTematem pracy była synteza N-alkilowych pochodnych D-glukosaminy i 2-amino-2-deoxy-D-glukitolo-6-fosforanu
-
The effect of anionic surfactant concentration on activated sludge condition and phosphate release in biological treatment plant
PublicationThis paper discusses the influence of a wide range of anionic surfactant concentrations on activated sludge. Linear alkylbenzene sulphonate (LAS) was chosen as an example of a commonly used anionic surfactant. The fate of the surfactant during biological treatment of wastewater was tested. The effect of surfactant on glucose and starch removal was studied.
-
Inactivation of glucosamine-6-phosphate synthase by N3-oxoacyl derivatives of L-2,3-diaminopropanoic acid
PublicationN3-oksoacylowe pochodne kwasu l-2,3-diaminopropanowego zawierające ugrupowanie epoksydowe lub układ sprzężonych wiązań podwójnych inaktywują syntaze glukozamino-6-fosforanu (GlcN-6-P) z S. cerevisiae. Wyniki badań kinetycznych inaktywacji enzymu wskazują na dwuetapowy przebieg tej reakcji, przy czym tworzenie kompleksu enzym:ligand poprzedza nieodwracalną modyfikację enzymu. Badane związki różniły się powinowactwem do centrum aktywnego...
-
Directly compressible formulation of immediate release rosuvastatin calcium tablets stabilized with tribasic calcium phosphate
Publication -
Phosphorylation of glucosamine-6-phosphate synthase is important but not essential for germination and mycelial growth of Candida albicans.
PublicationStosując mutagenezę ukierunkowaną dla genu gfa1 kodującego syntazę glukozamino-6-fosforanu Candida albicans otrzymano zmutowaną wersję GFA1S208A. Produkt zmutowanego genu, który utracił miejsce fosforylacji dla kinazy A, wykazywał wszystkie właściwości identyczne do dzikiego enzymu, jednakże nie był substratem dla kinazy. Brak fosforylacji syntazy glukozamino-6-fosforanu przez kinazęA prowadził do redukcji lecz nie eliminował...
-
Glutamine analogues containing a keto function - novel inhibitors of fungal glucosamine-6-phosphate synthase
PublicationW publikacji przedstawiono syntezę nowych pochodnych kwasu (S)-2,3-diaminopropanowego, zawierających reszty kwasów z funkcją ketonową. Dla otrzymanych związków zbadano właściwości inhibicyjne w stosunku do grzybowej syntazy glukozamino-6-fosforanu, ustalono właściwości lipofilowe otrzymanych związków a także aktywność przeciwgrzybową. Dla kilku wybranych pochodnych otrzymano ich dipeptydy, zbadano także ich aktywność przeciwgrzybową...
-
Comparison of the effect of montmorillonite, magnesium hydroxide and a mixture of both on the flammability properties and mechanism of char formation of HDPE composites
Publication -
Single-Step Symmetrical Double Alkylation of β,γ-Unsaturated δ-Lactams via Magnesium ‘Ate’ Complexes
Publication -
A Probe into the Corrosion Behavior of a WE43B Magnesium Alloy in a Simulated Body Fluid using Dynamic Electrochemical Impedance Spectroscopy
PublicationWE43B is one of the newest Mg alloys with practical application in biomedical implant technology. This work attempts to scrutinize the corrosion characteristics of WE43B alloy in a simulated body fluid (SBF) at a typical body temperature. The dynamic-electrochemical impedance spectroscopy with the capacity to track changes on surfaces in a dynamic corrosive system is used in combination with other classical techniques namely, linear...
-
Visualizing the Dose Distribution and Linear Energy Transfer by 1D and 2D ESR Imaging: A Potassium Dithionate Dosimeter Irradiated with C6+ and N7+ Ions
Publication -
Sporothrix schenckii: purification and partial biochemical characterisation of glucosamine-6-phosphate synthase, a potential antifungal target
PublicationW artykule opisano izolację i charakterystykę właściwości natywnego enzymu, syntazy GlcN-6-P z komórek dimorficznego grzyba patogennego Sporothrix schenckii. Masę cząsteczkową enzymu natywnego określono na 350 kDa, a enzymu zdenaturowanego na około 79 kDa, co sugeruje homotetrameryczną strukturę białka. Wartość punktu izoelektrycznego wyniosła 6,26; wyznaczono także parametry kinetyczne katalizowanej reakcji. Aktywność enzymu była...
-
The Use of Calcium Phosphate-Based Starter Pellets for the Preparation of Sprinkle IR MUPS Formulation of Rosuvastatin Calcium
Publication -
Experimental Investigation Of Using Latent Thermal Energy Storage System Comprising Of Magnesium Chloride Hexahydrate (MgCl2.6H2O) With Domestic Gas Heater
Publication -
A facile hydrous mechano-synthesis of magnesium hydroxide [Hy-Mg(OH)2] nano fillers for flame-retardant polyester composites
Publication -
Influence of selenium and/or magnesium on alleviation alcohol induced oxidative stress in rats, normalization function of liver and changes in serum lipid parameters
Publication -
Noncryogenic Synthesis of Functionalized 2-Methoxypyridines by Halogen-Magnesium Exchange Using Lithium Dibutyl(isopropyl)magnesate(1-) and Lithium Chloride
Publication -
Bioactive monolithic composites of silica/polydimethylsiloxane/calcium phosphate obtained at room temperature in sol–gel micromolding technique
Publication -
Correction to “Emerging Anticancer Activity of Candidal Glucosamine-6-Phosphate Synthase Inhibitors upon Nanoparticle-Mediated Delivery”
Publication -
Phosphate exchange across the sediment-water interface under oxic and hypoxic/anoxic conditions in the southern Baltic Sea
Publication -
Crystallization and preliminary X-ray analysis of the isomerase domain of glucosamine-6-phosphate synthase from Candida albicans
PublicationSyntaza glukozamino-6-fosforanu (EC 2.6.1.16) katalizuje pierwszy, praktycznie nieodwracalny etap w szlaku biosyntezy heksozoamin, którego produktem końcowym jest UDP-GlcNAc, kluczowy substrat dla tworzenia ściany komórkowej drobnoustrojów. Otrzymano kryształy domeny izomerazowej syntazy GlcN-6-P z Candida albicans, składającej się z reszt 346-712 (42 kDa). Analiza rentgenograficzna kryształu wykazała, że należy on do grupy przestrzennej...
-
Volumetric and acoustic properties of D-mannitol in aqueous sodium or magnesium(II) chloride solutions over temperature range of 293.15 to 313.15 K
PublicationWykorzystując zmierzone wartości gęstości oraz prędkości rozchodzenia się dźwięku wyznaczono pozorne objętości molowe i pozorne ściśliwości molowe D- mannitolu w (1, 5 i 10) % wodnych roztworach chlorku sodu oraz chlorku magnezu(II). Obliczono graniczne wartości pozornych wielkości molowych, odpowiednie funkcje przeniesienia oraz współczynniki rozszerzalności. Otrzymane wielkości powiązano z oddziaływaniami D-mannitol -sól (NaCl...
-
Application of biocompatible and ultrastable superparamagnetic iron(iii) oxide nanoparticles doped with magnesium for efficient magnetic fluid hyperthermia in lung cancer cells
Publication -
The influence of phosphorus fractions in bottom sediments on phosphate removal in semi-natural systems as the 3rd stage of biological wastewater treatment
PublicationThe research was carried out in two semi-natural systems (the polishing ponds in Swarzewo and the free water surface constructed wetland in Zarnowiec) in Poland. They were built as the 3rd stage of a conventional mechanical–biological wastewater treatment plant. These systems were built to improve the quality of the effluent of treated wastewater. In the polishing ponds and FWS wetland system, suspended solids, organic matter as...
-
Construction, purification, and functional characterization of His-tagged Candida albicans glucosamine-6-phosphate synthase expressed in Escherichia coli
Publication -
An Excess Electron Bound to Magnesium Halides and Basic Grignard Compounds (RMgX and RMgR, R = Me, Et, Ph; X = F, Cl, Br)
Publication -
Synthesis and Physicochemical Properties of [(1R,2S,5R)-2-isopropyl-5-methylcyclohexyloxy]-thiophen-5-yl-substituted Tetrapyrazinoporphyrazine with Magnesium(II) Ion
Publication -
The structure of dimethylsulfoxide-solvated magnesium and calcium ions in solution and the solid state, and overview of the coordination chemistry of hydrated and solvated alkaline earth metal ions
PublicationOznaczono strukturę w stanie stałym i ciekłym solwatowanych jonów magnezu i wapnia w dimetylosulfotlenku. Stwierdzono, ze jony te tworzą sześciokoordynacyjne solwaty ze średnią długością wiązań Mg-O i Ca-O 2.062(4) i 2.303(5)A. Przegląd literaturowy ukazał, że jony berylu i magnezu we wszystkich rozpuszczalnikach tworzą odpowiednio cztero- i sześciokoordynacyjne solwaty, podczas gdy jony wapnia i strontu istnieją jako ośmiokoordynacyjne...
-
Fuzzy reasoning approach to properties' determination of calcium phosphate coatings processed using ion beam assisted deposition on heated substrates
PublicationPraca przedstawia rozmyty system wnioskowania dla zamodelowania związków pomiędzy temperaturą podłoża oraz stosunkiem molowym Ca/P w gradientowej powłoce hydroxyapatytowej na podłożu tytanowym. Przeprowadzono symulację działania sterownika rozmytego na pomocą oprogramowania Matlab.
-
Pore water phosphate and ammonia below the permanent halocline in the south-eastern Baltic Sea and their benthic fluxes under anoxic conditions
Publication -
Impact of the 2014 Major Baltic Inflow on benthic fluxes of ferrous iron and phosphate below the permanent halocline in the southern Baltic Sea
Publication -
Study of effect of phosphate and uranium ions on the thermal properties of surfactant-modified natural red clay using TG–FTIR–MS techniques
Publication -
Development of biocompatible iron oxide-silicon oxide core-shell nanoparticles as subcellular delivery platform for glucosamine-6-phosphate synthase inhibitors
PublicationIn order to develop the preparation of iron oxide-silica coreshell nanoparticles (CSNPs), thesis deeply explores the cetyltrimethylammonium (CTA+) directed silica coating methods of the oleic-acid capped iron oxide nanoparticles (OA-IONPs) initialized under near-neutral pH conditions. It is demonstrated that the initial alkaline hydrolysis of ethyl acetate in the presence of CTA+ and OA-IONPs induces an unusual ligand exchange...
-
Magnesium-Doped Sr2(Fe,Mo)O6−δ Double Perovskites with Excellent Redox Stability as Stable Electrode Materials for Symmetrical Solid Oxide Fuel Cells
Publication -
The synthesis and biological activity of lipophilic derivatives of bicine conjugated with n3-(4-methoxyfumaroyl)-l-2,3-diaminopropanoic acid(fmdp) - an inhibitor of glucosamine-6-phosphate synthase
PublicationOtrzymano serię pochodnych bicyny połączonych z inhibitorem syntazy glukozamino-6-fosforanu (fmdp)oraz zbadano ich właściwości lipofilowe i aktywność przeciwgrzybową. otrzymane związki charakteryzowały się wyższą llipofilowością niż fmdp. wszystkie otrzymane związki wykazywały także wyższą aktywność przeciwgrzybową niż fmdp.
-
Potassium Tri-tert-butoxysilanethiolates: Synthesis, Properties, and Crystal and Molecular Structures of [(tBuO)3SiSK]6[THF]2·2THF, {[(tBuO)3SiS]2K2}n, and [(tBuO)3SiSK]4[H2O]4·C6H6
PublicationW reakcji tri-tert-butoksysilanotiolu z potasem otrzymano trzy nowe związki:[(tBuO)3SiSK]6[THF]2·2THF, {[(tBuO)3SiS]2K2}n, i[(tBuO)3SiSK]4[H2O]4·C6H6. Stanowią one dogodne substraty w syntezach kompleksów silanotiolanowych metali przejściowych. Charakteryzują się one również różnorodnością tworzonych układów. Rentgenowska analiza strukturalna wykazała, iż tworzą one trzy typy makrocząsteczkowych układów, w których...
-
The effect of using jug-type water filters on selected metals concentration in tap water – a case study
PublicationIn this study, the effect of the filtration process on Na, K, Mg, Ca, Fe and Zn concentration in water, using filters from one of the leading European manufacturers, was investigated. The increase in Na (up to 300%) and K concentration (up to 320%) at the beginning of jug filter usage was reported. A decrease in Ca, Fe and Zn concentration was observed. Standard filters remove 80–90% of Mg from tap water at the beginning of the...
-
The impact of cold plasma on the phenolic composition and biogenic amine content of red wine
PublicationThe effect of cold plasma (CP) on phenolic compound (PC) and biogenic amine (BA) contents of red wine was investigated for the first time. The influence of CP was compared with the effects of a wine preservation using potassium metabisulfite and a combined method. The PC profile was determined by UPLC-PDA-MS/MS while BAs using DLLME-GC–MS. Chemometric analysis also was used. The content of PCs was 3.1% higher in the sample preserved...
-
Glyceraldehyde - 3 - phosphate dehydrogenase gen from Amanita citrina. Ac-cession AJ532582, 2002 GenBank NCBI [on line].**2002 [cytowany 07.01.03]. Dostępny: http://www.ncbi.nml.nih.gov Sekwencja genu kodującego dehydrogenzę aldehydu - 3 - fsfoglicerynowego dla muchomora cytrynowego (Amanita citrina).
PublicationPo raz pierwszy ustalono sekwencję nukleotydową fragmentu genu gpd (dehydro-genazy aldehydu - 3 - fosfoglicerynowego) dla muchomora cytrynowego (Amanitacitrina), pozwoli to na ustalenie sekwencji starterów umożliwiających wykry-wanie grzybów tego gatunku za pomocą techniki PCR.
-
Glyceraldehyde - 3 - phosphate dehydrogenase gene from Coprinus atramenta-rius. Accession AJ532581, 2002 GenBank NCBI [on line].**2002 [cytowany 07.01.03]. Dostępny: http://www.ncbi.nlm.nih.gov Sekwencja genu kodujacego dehydrogenazę aldehydu - 3 - fosfoglicerynowego dla czernidłaka pospolitego (Coprinus atramentarius).
PublicationPo raz pierwszy ustalono sekwencję nukleotydową fragmentu genu gpd (dehydro-genazy aldehydu - 3 - fosfoglicerynowego)dla gatunku Coprinus atramentarius,pozwoli to na zaprojektowanie pary starterów umożliwiających wykrywaniegrzybów tego gatunku za pomocą reakcji PCR.
-
The strategies of nutrient removal compounds from wastewater by using aquatic plants in the Green deal implementation
PublicationThe aim of the study was to determine the efficiency of wastewater treatment from nitrogen compounds - ammonium, nitrite, nitrate, and phosphate - using Lemna minor and Spirogyra sp. in the context of the strategies toward Green Deal Implementation. Meanwhile, the various biological treatment methods of nutrients according to the value-added and application prospects were also discussed as a future solution in the Circular Economy...
-
PRELIMINARY RESULTS FROM APPLICATION PHOSLOCK® TO REMOVE PHOSPHORUS COMPOUNDS FROM WASTEWATER
PublicationThe aim of the study is to assess the removal effectiveness of phosphorus compoundsby using lanthanum-modified bentonite. This material was produced by the Australian company Phoslock® Water Solutions Pty Ltd. According to the company, Phoslock® has substantial capacity to bound phosphate anions. The investigation was carried out in steady conditions in laboratory model with beakers. The results of the study are related to the...
-
Effect of Nb and Al on in vitro dissolution behavior and structure of Na2O-MgO CaO-P2O5 glasses
PublicationIn vitro dissolution, structure, and thermal properties of the glass series Na2O-MgOsingle bondCaOsingle bondNb2O5 -Al2O3-P2O5 were studied. The dissolution behavior in phosphate-buffered saline (PBS) confirmed the potential bioactive properties of tested glasses. The dissolution process was found to depend on the Al, Nb, and Mg contents. Al, respectively, suppresses the Nb and accelerates the Mg release process from the glasses....
-
Bioactive core material for porous load-bearing implants
PublicationSo far state of knowledge on biodegradable materials is reviewed. Among a variety of investigated materials, those composed of polymers and ceramics may be considered as only candidates for a core material in porous titanium alloy. The collagen and chitosan among natural polymers, polyhydroxy acids among synthetic polymers, and hydroxyapatite and tricalcium phosphate among ceramics are proposed for further research. Three essential...
-
The role of slowly biodegradable organic compounds in a full-scale biological nutrient removal activated sludge systems
PublicationThe aim of this study was to determine the immediate effects of slowly biodegradable substrates on the denitrification capability and phosphate release/uptake interactions for a full-scale biomass process from two large wastewater treatment plants (WWTPs) located in the cities of Gdansk and Gdynia (northern Poland). Since it is hard to distinguish the slowly biodegradable substrate in a direct way, a novel procedure based on batch...
-
Synthesis of thiol derivatives of azobenzocrown ethers. The preliminary studies on recognition of alkali metal ions by gold nanoparticles functionalized with azobenzocrown and lipoic acid
PublicationThe article presents the synthesis of novel 13- and 16-membered azobenzocrown derivatives with peripheral thiol moieties and preliminary studies assessing their possible application in plasmonic sensors based on gold nanoparticles. The effect of the length of the chain connecting the macrocycle with the thiol group and the effect of the presence of the additional functional compound,...
-
Synthesis of 2-amino-2,6-dideoxy-D-glucitol-6-sulfonic acid as a potential antifungal agent.
PublicationGlucosamine-6P (GlcN-6P) synthase catalyzes the first committed step in the biosynthetic pathway leading to the formation of UDP-GlcNAc, a sugar nucleotide precursor providing D-glucosamine for the formation of chitin and manoproteins. 2-Amino-2,6-dideoxy-D-glucitol-6-sulfonic acid is an analog of 2-amino-2-deoxy-D-glucitol 6-phosphate (GlcN-ol-6-P), a known inhibitor of GlcN-6-P synthase, in which the phosphate group of the latter...