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Search results for: drug delivery devices
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INTERNATIONAL JOURNAL OF NUMERICAL MODELLING-ELECTRONIC NETWORKS DEVICES AND FIELDS
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Formation of Highly Conductive Boron-Doped Diamond on TiO2 Nanotubes Composite for Supercapacitor or Energy Storage Devices
PublicationIn the present paper, we report the phenomena of the formation of the novel composite nanostructures based on TiO2 nanotubes (NTs) over-grown by thin boron-doped diamond (BDD) film produced in Microwave Plasma Enhanced Chemical Vapor Deposition (PE MWCVD). The TiO2 nanotube array overgrown by boron-doped diamond immersed in 0.1 M NaNO3 can deliver high specific capacitance of 7.46 mF cm−2. The composite electrodes were characterized...
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Effect of buffer layers on performance of organic photovoltaic devices based on copper phthalocyanine-perylene dye heterojunction
PublicationPraca przedstawia wyniki badań układu fotowoltaicznego złożonego z cienkich warstw organicznych tworzących złącze (CuPc i MePTCDI), elektrod (ITO i Ag) oraz z warstw buforowych (MoO3 przy ITO i BCP przy Ag).
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New devices to capture the temperature effect under dynamic compression and impact perforation of polymers, application to PMMA
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Mathematical Models of Control Systems of Angular Speed of Steam Turbines for Diagnostic Tests of Automatic and Mechatronic Devices
PublicationAccurate modeling of physical processes of many automatics and mechatronics systems is often necessity. In power system such a process is control of angular velocity of power objects during connection to operation in parallel. This process is extremely dynamic. For this reason response of control system depends from changes of many physical parameters (temperature, pressure and flow of the medium, etc.). Precision modeling influences...
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All-fiber tunable devices based on high-index photonic crystal fibers filled with liquid crystals
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Assessing the Operation System of Fire Alarm Systems for Detection Line and Circuit Devices with Various Damage Intensities
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Ability of paramedics to perform intraosseous access. A randomized cadaver study comparing EZ-IO® and NIO® devices
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The Quantum Efficiency Roll-Off Effect in Near-Infrared Organic Electroluminescent Devices with Iridium Complexes Emitters
PublicationThe electroluminescence quantum efficiency roll-off in iridium(III)-based complexes, namely Ir(iqbt)2(dpm) and Ir(iqbt)3(iqbt=1 (benzo[b]thiophen-2-yl)-isoquinolinate, dpm=2,2,6,6-tetramethyl-3,5-heptanedionate) utilized as near-infrared emitters in organic light emitting diodes with remarkable external quantum efficiencies, up to circa 3%, 1.5% and 1%, are measured and analyzed. With a 5–6 weight % of emitters embedded...
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Photoplethysmographic Time-Domain Heart Rate Measurement Algorithm for Resource-Constrained Wearable Devices and its Implementation
PublicationThis paper presents an algorithm for the measurement of the human heart rate, using photoplethysmography (PPG), i.e., the detection of the light at the skin surface. The signal from the PPG sensor is processed in time-domain; the peaks in the preprocessed and conditioned PPG waveform are detected by using a peak detection algorithm to find the heart rate in real time. Apart from the PPG sensor, the accelerometer is also used to...
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Real‐Time PPG Signal Conditioning with Long Short‐Term Memory (LSTM) Network for Wearable Devices
PublicationThis paper presents an algorithm for real‐time detection of the heart rate measured on a person’s wrist using a wearable device with a photoplethysmographic (PPG) sensor and accelerometer. The proposed algorithm consists of an appropriately trained LSTM network and the Time‐Domain Heart Rate (TDHR) algorithm for peak detection in the PPG waveform. The Long Short‐Term Memory (LSTM) network uses the signals from the accelerometer...
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Inhibition of ALDH1A1 activity decreases expression of drug transporters and reduces chemotherapy resistance in ovarian cancer cell lines
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Microarray-based detection and expression analysis of new genes associated with drug resistance in ovarian cancer cell lines
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Novel 2019 coronavirus structure, mechanism of action, antiviral drug promises and rule out against its treatment
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The antitumor derivative, C-1748, affects CYP3A4: crosstalk between drug metabolism, CYP3A4 expression and enzymatic activity
PublicationJedną z głównych przeszkód w przewidywaniu wyników terapii u pacjentów z nowotworem jest indywidualny przebieg metabolizmu stosowanych leków wynikający z polimorfizmu genów enzymów metabolizujących, jak również duża zmienność farmakokinetyki leków obserwowana u różnych pacjentów podczas trwania chemioterapii. Z powodu tzw. ''wąskiego okna terapeutycznego'' występującego w przypadku terapii lekami przeciwnowotworowymi, małe zmiany...
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DNA structure and integrity checkpoints in the cell cycle and their role in drug targeting and resistance of tumor cells to anticancer treatment
PublicationW artykule dokonaliśmy przeglądu literatury dotyczącej różnych typów uszkodzeń DNA indukowanych przez różne czynniki terapeutyczne w komórkach nowotworowych. Omówiliśmy także w jaki sposób aktywują różne typy punktów kontrolnych w cyklu komórkowym i w jaki sposób punkty te są regulowane przez inne szlaki sygnalizacji wewnątrzkomórkowej takie jak szlaki naprawy uszkodzeń DNA, stresu komórkowego i śmierci-przeżycia. W szczególności...
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Impact of orthostatic hypotension and antihypertensive drug treatment on total and cardiovascular mortality in a very elderly community-dwelling population
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High mortality explained by mildly elevated blood pressure in Scandinavian adolescent conscripts – A plea for early drug treatment?
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Semi-continuous production of the anticancer drug taxol by Aspergillus fumigatus and Alternaria tenuissima immobilized in calcium alginate beads
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Development of biocompatible iron oxide-silicon oxide core-shell nanoparticles as subcellular delivery platform for glucosamine-6-phosphate synthase inhibitors
PublicationIn order to develop the preparation of iron oxide-silica coreshell nanoparticles (CSNPs), thesis deeply explores the cetyltrimethylammonium (CTA+) directed silica coating methods of the oleic-acid capped iron oxide nanoparticles (OA-IONPs) initialized under near-neutral pH conditions. It is demonstrated that the initial alkaline hydrolysis of ethyl acetate in the presence of CTA+ and OA-IONPs induces an unusual ligand exchange...
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Fundamentals of Machinery Operation and Power Engineering Devices, L, ENE, sem. 5, zima 2022/23 (PG_00042101)
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Fundamentals of Machinery Operation and Power Engineering Devices, W, PE, sem 05, zimowy 23/24 (PG_00042101)
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Fundamentals of Machinery Operation and Power Engineering Devices, L, ET, sem.5, zima 23/24 (PG_00042101)
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CURRENT CANCER DRUG TARGETS
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CURRENT OPINION IN DRUG DISCOVERY & DEVELOPMENT
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Current Computer-Aided Drug Design
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CNS & Neurological Disorders-Drug Targets
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Acta Poloniae Pharmaceutica - Drug Research
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EUROPEAN JOURNAL OF DRUG METABOLISM AND PHARMACOKINETICS
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ANTISENSE & NUCLEIC ACID DRUG DEVELOPMENT
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Expert Opinion on Drug Metabolism & Toxicology
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International Journal of Alcohol and Drug Research
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Journal of Global Drug Policy and Practice
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African Journal of Drug and Alcohol Studies
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Recent Patents on CNS Drug Discovery
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Drug Discovery Today: Disease Models
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Cardiovascular and Hematological Disorders - Drug Targets
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Current Research in Pharmacology and Drug Discovery
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AMERICAN JOURNAL OF DRUG AND ALCOHOL ABUSE
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PROBLEMS OF THE STARTING AND OPERATING OF HYDRAULIC COMPONENTS AND SYSTEMS IN LOW AMBIENT TEMPERATURE (PART V) METHODS ENSURING CORRECT START-UP OF HYDRAULIC COMPONENTS OF SHIP’S ONBOARD DEVICES IN LOW AMBIENT TEMPERATURES
PublicationA large number of hydraulic devices and systems are started in low ambient temperatures. A good example of such a device is the hoisting winch on the ship. Starting hydraulic drive units in thermal shock conditions (rapid supply of hot oil to the cold unit) may lead to incorrect operation of the actuating system, for instance, due to the loss of clearance between cooperating elements. The article presents methods to prevent the...
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Nanoemulsion Structural Design in Co-Encapsulation of Hybrid Multifunctional Agents: Influence of the Smart PLGA Polymers on the Nanosystem-Enhanced Delivery and Electro-Photodynamic Treatment
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Renal denervation achieved by endovascular delivery of ultrasound in RADIANCE-HTN SOLO or by radiofrequency energy in SPYRAL HTN-OFF and SPYRAL-ON lowers blood pressure
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Aminopropyl-functionalized mesoporous silica SBA-15 as drug carrier for cefazolin: adsorption profiles, release studies, and mineralization potential
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Monolithic polydimethylsiloxane-modified silica composites prepared by a low-temperature sol–gel micromolding technique for controlled drug release
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Expression of Osteoblast-Specific Factor 2 (OSF-2, Periostin) Is Associated with Drug Resistance in Ovarian Cancer Cell Lines
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PTPRK Expression Is Downregulated in Drug Resistant Ovarian Cancer Cell Lines, and Especially in ALDH1A1 Positive CSCs-Like Populations
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Preliminary Investigation of the Antibacterial Activity of Antitumor Drug 3-Amino-1,2,4-Benzotriazine-1,4-Dioxide (Tirapazamine) and its Derivatives
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Development and Validation of a Gas Chromatography Method for the Trace Level Determination of Allylamine in Sevelamer Hydrochloride and Sevelamer Carbonate Drug Substances
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Core/shell structured silica spheres with controllable thickness of mesoporous shell and its adsorption, drug storage and release properties
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Transport Mechanism of Paracetamol (Acetaminophen) in Polyurethane Nanocomposite Hydrogel Patches—Cloisite® 30B Influence on the Drug Release and Swelling Processes
PublicationThis article describes the swelling and release mechanisms of paracetamol in polyurethane nanocomposite hydrogels containing Cloisite® 30B (organically modified montmorillonite). The transport mechanism, swelling and release processes of the active substance in nanocomposite matrix were studied using gravimetric and UV-Vis spectroscopic methods. Swelling and release processes depend on the amount of clay nanoparticles in these...