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Glutathione conjugation of the antitumor-active 1-nitroacridine derivatives compounds C-857 and C-1748 – the major role of glutathione S-transferase M1-1
Open Research DataObjectives: C-857 and C-1748 are antitumor-active agents, monomers of unsymmetrical bisacridine derivatives. The aim of this study was to analyze their glutathione (GSH) conjugation in vitro in the presence of glutathione S-transferase (GST) M1-1.
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Sex Education: Sexuality, Society and Learning
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The Journal of Adventure Education and Outdoor Learning
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International Electronic Journal for Leadership in Learning
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Journal of Structural Learning and Intelligent Systems
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International Journal for Lesson and Learning Studies
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International Journal of Management, Knowledge and Learning
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International Journal of Mobile and Blended Learning
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Canadian Journal for the Scholarship of Teaching and Learning
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International Journal of Machine Learning and Cybernetics
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GIST-Education and Learning Research Journal
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International Journal of Information and Learning Technology
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Bulletin of the Technical Committee on Learning Technology
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Studies in Second Language Learning and Teaching
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International Journal of Game-Based Learning
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BMJ Simulation & Technology Enhanced Learning
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Journal of University Teaching and Learning Practice
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International Journal of Emerging Technologies in Learning
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Journal of E-Learning and Knowledge Society
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International Journal of Learning and Intellectual Capital
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International Journal of Technology Enhanced Learning
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International Journal of Research in E-learning
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Interdisciplinary Journal of Problem-Based Learning
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International Journal of Work-Integrated Learning
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International Journal of Machine Learning and Computing
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Studies in Self-Access Learning Journal
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Visual Inquiry-Learning & Teaching Art
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International Journal of Early Childhood Learning
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Per Linguam-A Journal of Language Learning
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Teaching & Learning Inquiry-The ISSOTL Journal
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International Journal of Mobile Learning and Organisation
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International Journal of Learning in Higher Education
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Journal of Education and e-Learning Research
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Adults Learning Mathematics International Journal
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Journal of Teaching and Learning for Graduate Employability
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Journal of Digital Learning in Teacher Education
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Journal of Research in Innovative Teaching and Learning
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Research and Practice in Technology Enhanced Learning
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Ijaz Arabi Journal of Arabic Learning
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Language Learning and Technology (LL&T)
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Minerva - A Review of Science, Learning and Policy
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MedEdPORTAL : the journal of teaching and learning resources
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Antike Kunst. Zeitschrift für klassische Archäologie
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Salinity enhances high optically active L-lactate production from co-fermentation of food waste and waste activated sludge: Unveiling the response of microbial community shift and functional profiling
PublicationLactic acid (LA), a versatile platform molecule, can be fermented from organic wastes, such as food waste and waste activated sludge. In this study, an efficient approach using salt, a component of food waste as an additive, was proposed to increase LA production. The LA productivity was increased at 10 g NaCl/L and optical pure L-lactate was obtained at 30 g NaCl/L. The enhancement of LA was in accordance with the increased solubilization...
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Identyfikacja i izolacja genu kodującego zaadaptowaną do zimna β-galaktozydazę Paracoccus sp. = Identification and izolation of the gene encoding cold-active β-galactosidase from paracoccus sp.
PublicationZaprezentowane badania były prowadzone u eehi wyizolowania ze środo¬wiska organizmu psychrofilnego, zdolnego do hydrolizy laktozy w niskiej tempe¬raturze, oraz zidentyfikowania genu kodującego (i-galaktozydazę zaadaptowaną do zimna.Poszukiwan gen został w izolowany z psychrofilnego szczepu autarkicz¬nego Paracoccus sp. 321). Na podstawie sekwencji nukleotydowej genu kodują¬cego fS-galaktozdaze ustalono skład aminokwasów),...
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An MTA-phosphorylase gene discovered in the metagenomic library derived from Antarctic top soil during screening for lipolytic active clones confers strong pink fluorescence in the presence of rhodamine B.
PublicationIn this work, we present the construction of a metagenomic library in Escherichiacoli using the pUC19 vector and environmental DNA directly isolated fromAntarctic topsoil and screened for lipolytic enzymes. Unexpectedly, the screeningon agar supplemented with olive oil and rhodamine B revealed one unusual pinkfluorescent clone (PINKuv) out of 85 000 clones. This clone harbored a plasmid,pPINKuv, which has an insert of 8317 bp that...
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Synthesis and biological evaluation of 2,7-Dihydro-3H-dibenzo[de,h]cinnoli- ne-3,7-done derivatives a novel group of anticancer agents active on a multidrug resistance cell line.
PublicationZsyntezowano serię pochodnych pirydazonu z jednym lub dwoma łańcuchami bocznymi w różnych pozycjach chromoforu tetracyklicznego. Związki wykazały aktywność cytoksyczną na mysią białaczkę L1210 i ludzką k562 oraz na linii komórkowej oporności krzyżowej MDR (k562/DX). Dwa najbardziej aktywne związki przetestowano in vivo na mysiej białaczce P388. Wykazały one aktywność przeciwnowotworową porównywalną z aktywnością Mitoxantronu.
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Overproduction of homoserine O-acetyltransferase (CaMet2p) native and His-tag versions.
Open Research DataEnzyme of fungal L-methionine biosynthetic pathway: homoserine O-acetyltransferase (Met2p) could be exploited as molecular target for antifungal chemotherapy. The goal of the study was to obtain conditions optimal for protein production with the use of prokaryotic cells. The constructed expression plasmids, designed in three different versions: encoding...
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Light4Health eLearning Course: health research for interior lighting design. Re-thinking design approaches based on science
PublicationThis paper presents the results of 'Light4Health' (L4H), a three-year EU Erasmus+ Strategic Partnership grant project (2019-2021), which investigated, systematized and taught health-related research on the impact of natural and artificial light on human health and well-being relevant to indoor lighting design. The objective was to re-think evidence-based lighting design approaches for residential, working/educational, and healthcare...
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eLearning im Wandel der Zeit am Beispiel der TU Gdansk und der FH Flensburg
PublicationW referacie omówiono zmiany systemów eLearning na przykładzie ich rozwoju na Politechnice Gdańskiej i w Wyższej Szkole Zawodowej we Flensburgu. Dokonano analizy pierwszych rozwiązań, w tym własnych systemów i narzędzi, jak również dokonanego na obu uczelniach zwrotu w kierunku otwartych systemów LMS. Podkreślono rolę oceny jakości(QoS) systemów zdalnego nauczania.