displaying 1000 best results Help
Search results for: NON-SMALL-CELL LUNG CANCER
-
Effects of Non-Opioid Analgesics on the Cell Membrane of Skin and Gastrointestinal Cancers
Publication -
Ewa Klugmann-Radziemska prof. dr hab.
PeopleEwa Klugmann-Radziemska graduated from the University of Gdansk with a degree in physics, and since 1996 has been associated with the Gdansk University of Technology, when she began PhD studies. Currently, he is a professor at the Faculty of Chemistry at the Gdansk University of Technology, since 2006 head of the Department of Chemical Apparatus and Machinery. In the years 2008–2016 she was the Vice-Dean for cooperation and development,...
-
Structure–bioavailability relationship study of genistein derivatives with antiproliferative activity on human cancer cell
Publication -
Drug transporter expression profiling in chemoresistant variants of the A2780 ovarian cancer cell line
Publication -
Translational Lung Cancer Research
Journals -
C421 allele-specific ABCG2 gene amplification confers resistance to the antitumor triazoloacridone C-1305 in human lung cancer cells
PublicationGen ABCG2 charakteryzuje polimorficzność pozycji C341, która jest związana ze znacznym obniżeniem ekspresji tego genu i zdolności do transportu przez błonę komórkową. W pracy wykazaliśmy, że komórki raka płuc, które nabyły oporności na związek C-1305, zmieniły fenotyp z heterozygotycznego w odniesieniu do genu ABCG2 i wykazują amplifikację jedynie allelu C341 genu oraz zwiększoną zawartość mRNA i zmutowanego białka pompy ABCG2...
-
Increased plasma concentration of 4-pyridone-3-carboxamide-1-ß-D-ribonucleoside (4PYR) in lung cancer. Preliminary studies
Publication -
Small isomeric push–pull chromophores based on thienothiophenes with tunable optical (non)linearities
Publication -
Cancer stem cells in drug resistance and drug screening: can we exploit the cancer stem cell paradigm in search for new antitumor agents?
PublicationPraca przedstawia przegląd literatury dotyczącej hipotezy komórek pierwotnych nowotworu, w szczególności w ich oporności na istniejące terapie. Dyskutowane jest także zagadnienie możliwości wykorzystania wiedzy o tych komórkach do konstrukcji nowych testów do badań przesiewowych in vitro w celu poszukiwania nowych leków przeciwnowotworowych.
-
Cancer Cell International
Journals -
Poly(amidoamine) Dendrimer/Camptothecin Complex: From Synthesis to In Vitro Cancer Cell Line Studies
Publication -
Increased Expression of Several Collagen Genes is Associated with Drug Resistance in Ovarian Cancer Cell Lines
Publication -
Extracellular Matrix Proteins Expression Profiling in Chemoresistant Variants of the A2780 Ovarian Cancer Cell Line
Publication -
Application of biocompatible and ultrastable superparamagnetic iron(iii) oxide nanoparticles doped with magnesium for efficient magnetic fluid hyperthermia in lung cancer cells
Publication -
Comparison of peptide cancer signatures identified by mass spectrometry in serum of patients with head and neck, lung and colorectal cancers: Association with tumor progression
Publication -
c-Myc Protein Level Affected by Unsymmetrical Bisacridines Influences Apoptosis and Senescence Induced in HCT116 Colorectal and H460 Lung Cancer Cells
PublicationUnsymmetrical bisacridines (UAs) are highly active antitumor compounds. They contain in their structure the drugs previously synthesized in our Department: C-1311 and C-1748. UAs exhibit different properties than their monomer components. They do not intercalate to dsDNA but stabilize the G-quadruplex structures, particularly those of the MYC and KRAS genes. Since MYC and KRAS are often mutated and constitutively expressed in cancer...
-
Ewa Augustin dr hab.
People -
Non-vitamin K antagonist oral anticoagulants (NOACs) in cancer patients with atrial fibrillation
Publication -
Virtual screening for small molecular non-covalent binders of the SARS-CoV-2 main protease
Publication -
A non-quasi-static small-signal model of the four-terminal MOSFET for radio and microwave frequencies.
PublicationW pracy zaprezentowano nowy małosygnałowy model tranzystora MOS, w którymuwzględnia się efekt nasycenia prędkości nośników. Model jest spójny fizycznie i może być stosowany w analizie dowolnej konfiguracji włączenia tranzystora.
-
Study of Bioreductive Anticancer Agent RH-1-Induced Signals Leading the Wild-Type p53-Bearing Lung Cancer A549 Cells to Apoptosis
Publication -
The Role of Matrix Gla Protein (MGP) Expression in Paclitaxel and Topotecan Resistant Ovarian Cancer Cell Lines
Publication -
New and Old Genes Associated with Primary and Established Responses to Paclitaxel Treatment in Ovarian Cancer Cell Lines
Publication -
Analysis of MDR genes expression and cross-resistance in eight drug resistant ovarian cancer cell lines
Publication -
Proteomic profile of melanoma cell‐derived small extracellular vesicles in patients’ plasma: a potential correlate of melanoma progression
Publication -
R&D of satellite pumps and motors with small geometrical displacement supplied with oil and non-flammable liquids
PublicationThe newest construction of satellite motors and self-suction satellite pumps with small geometrical displacement have been described in this article. The characteristics of volumetric and total efficiency of one satellite motor, selected from the series, supplied with oil have been presented. These characteristics have been compared with the orbital motors' characteristics. The remaining specifications of these motors were also...
-
Radiation pattern measurements of geometrically small antennas performed in non-anechoic environments
Open Research DataThe dataset contains unprocessed measurements of radiation pattern characteristics performed in non-anechoic regime for three geometrically small antenna structures: a spline-parameterized Vivaldi structure, a compact spline-based monopole, and a quasi-Yagi geometry with enhanced bandwidth. The responses have been obtained over broad frequency ranges...
-
Synthesis of isomeric, oxathiolone fuded chalcones and comparison of their activity toward various microorganisms and human cancer cell lines
PublicationIzomeryczne oksationolowe sprzężone chalkony otrzymano w wyniku kondensacji odpowiedniego acetylobenzo[1,3]oksatiolo-2-onu z aldehydem benzoesowym w środowisku kwaśnym. Określono aktywność cytotoksyczną otrzymanych związków wobec komórek linii HeLa, przeciwbakteryjną wobec Micrococcus luteus, Staphylococcus aureus, Salmonella typhimurium, Escherichia coli i Proteus vulgaris, przeciwgrzybową wobec Candida albicans i tuberkulostatyczną...
-
Bacteria Residing at Root Canals Can Induce Cell Proliferation and Alter the Mechanical Properties of Gingival and Cancer Cells
Publication -
New and Old Genes Associated with Primary and Established Responses to Cisplatin and Topotecan Treatment in Ovarian Cancer Cell Lines
Publication -
Inhibition of ALDH1A1 activity decreases expression of drug transporters and reduces chemotherapy resistance in ovarian cancer cell lines
Publication -
Microarray-based detection and expression analysis of new genes associated with drug resistance in ovarian cancer cell lines
Publication -
Evaluation of inhibition of cancer cell proliferation in vitro with different berries and correlation with their antioxidant level by advanced analytical methods
PublicationW pracy opisano wyniki badań:- właściwości przeciwutleniających ekstraktów rozpuszczalnikowych (DMSO) uzyskanych z różnych gatunków owoców jagodowych- zdolność do infibizacji proliferacji komórek rakowych.W badaniach wykorzystano testy (DPPH) oraz zaawansowane techniki analityczne (spektroskopia FTIR oraz fluoroscencja 3D)Wyniki badań wskazują, że spożywanie owoców jagodowych może zredukować zagrożenie procesu proliferacji komórek...
-
Cancer stem cells and escape from drug-induced premature senescence in human lung tumor cells: implications for drug resistance and in vitro drug screening models
PublicationBadania z użyciem modelu komórek nowotworu płuc A549 wykazały, że komórki te po traktowaniu lekami uszkadzającymi DNA zatrzymują proliferację i wchodzą w stan starzenia komórkowego. Jednak post-inkubacja tych komórek prowadzi do powrotu do stanu proliferacji małej frakcji komórek. Wykazaliśy, że frakcja ta związana jest z obecnością komórek pierwotnych nowotworu w populacji komórek A549. Powrót do stanu proliferacji komóek A549...
-
Expression of stem cell and mesenchymal markers in circulating tumor cells is associated with poor prognosis of early breast cancer patients
Publication -
Expression of Osteoblast-Specific Factor 2 (OSF-2, Periostin) Is Associated with Drug Resistance in Ovarian Cancer Cell Lines
Publication -
PTPRK Expression Is Downregulated in Drug Resistant Ovarian Cancer Cell Lines, and Especially in ALDH1A1 Positive CSCs-Like Populations
Publication -
Discussion on 3-hydroxy-3-methylglutaryl-coenzyme a reductase inhibitors reduce human pancreatic cancer cell invasion and metastasis
Publication -
Genotoxicity of selected pharmaceuticals, their binary mixtures, and varying environmental conditions – study with human adenocarcinoma cancer HT29 cell line
PublicationPharmaceutical residues are present in the environment in mixtures and their adverse effects may also result from interactions that occur between compounds. Studies presented in this work focus on genotoxicity of pharmaceuticals from different therapeutic groups in mixtures and in individual solutions impacted with different environmental conditions assessed using comet assay (alkaline approach). Binary mixtures of pharmaceuticals...
-
BRCA1 Loss Preexisting in Small Subpopulations of Prostate Cancer Is Associated with Advanced Disease and Metastatic Spread to Lymph Nodes and Peripheral Blood
Publication -
Small field radiotherapy of head and neck cancer patients is responsible for oxidatively damaged DNA/oxidative stress on the level of a whole organism
Publication -
Phase IIa study of the CD19 antibody MOR208 in patients with relapsed or refractory B-cell non-Hodgkin’s lymphoma
Publication -
Time-Gating method with automatic calibration for accurate measurements of electrically small antenna radiation patterns in Non-Anechoic environments
PublicationNon-anechoic sites represent a cheap alternative to measurements of antennas in dedicated facilities. However, due to a high noise—from the external EM signal sources and multipath interferences—the quality of radiation patterns obtained in non-anechoic conditions is poor. The characteristics can be corrected using a time-gating method (TGM), which involves filtering of the noise based on temporal analysis of the measured signals....
-
Amplification of c-myc gene and overexpression of c-Myc protein in breast cancer and adjacent non-neoplastic tissue
Publication -
Piperine Targets Different Drug Resistance Mechanisms in Human Ovarian Cancer Cell Lines Leading to Increased Sensitivity to Cytotoxic Drugs
Publication -
The Significance of MicroRNAs Expression in Regulation of Extracellular Matrix and Other Drug Resistant Genes in Drug Resistant Ovarian Cancer Cell Lines
Publication -
The influence of 4-substituted and unsubstituted derivatives of 1-nitroacridine on the cell cycle and induction of apoptosis in human cancer HT29 and HeLa S3.
PublicationZbadano wpływ pochodnych 1-nitroakrydyny C-1748 i C-857, w stężeniach biologicznie istotnych, na cykl życiowy oraz indukcję apoptozy komórek raka jelita grubego HT29 oraz raka szyjki macicy HeLa S3. Metodą cytometrii przepływowej wykazano, że 4-metylo-1-nitroakrydyna C-1748 powoduje akumulację komórek HT29 w fazie S i komórek HeLa S3 w fazie G2 cyklu komórkowego zaś związek C-857 indukuje akumulację komórek HT29 i HeLa S3 w fazie...
-
Transmission measurements between two geometrically small Vivaldi antennas performed in non-anechoic propagation conditions
Open Research DataThe dataset contains unprocessed measurements of complex transmission (and reflection) characteristics obtained in non-anechoic regime for a geometrically small, broadband spline-parameterized Vivaldi structure. The measurement setup comprises two Vivaldi antennas with the same topology where one is used as a reference structure, and another one as...
-
Emphysema affects the number and appearance of solitary pulmonary nodules identified in chest low-dose computed tomography: a study on high risk lung cancer screenees recruited in Silesian District
Publication -
Deep Learning-based Recalibration of the CUETO and EORTC Prediction Tools for Recurrence and Progression of Non–muscle-invasive Bladder Cancer
Publication