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Search results for: AMYLOID INHIBITION
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L-Homoserine O-acetyltransferase (CaMet2p) activity and inhibition
Open Research DataThe dataset contains the description of methodology and data files with the results obtained spectrophotometrically at 412 nm to determine the rate of fungal enzyme activity. The goal of the study was to obtain conditions optimal for L-homoserine O-acetyltransferase (Met2p) activity as well as evaluation of inhibitory potential of commercially available...
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Results of pharmaceuticals mixtures toxicity on inhibition of bioluminescence of Vibrio fischeri (Microtox)
Open Research DataThe research was concerned with verifying the impact of mixtures of nine pharmaceuticals against a selected organism, i.e., the bacterium Aliivibrio fischeri. A. fisheri is used as a model organism in the monitoring of acute toxicity in environmental and reference samples in Microtox® systems. Tested pharmaceuticals, namely: diclofenac (sodium salt),...
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The corrosion studies of 3,4,5-trihydroxybenzoic acid as an effective corrosion inhibitor of low alloy steel
Open Research DataThe dataset contains the electrochemical studies evaluating if gallic acid is a corrosion inhibitor for low alloy steel. Three measurements were carried out each case; corrosion potential (label ecorr), electrochemical impedance spectroscopy (label eis) and cyclic polarization (label cp). The measurements were carried out in sodium chloride, acidified...
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The effect of pH change of oxyteracycline solutions on the on inhibition of bioluminescence of Vibrio fischeri (Microtox)
Open Research DataIn this study attempt was also made to determine whether a pH change of the sample containing oxyteracycline solutions affects the total toxicity of the sample using the Microtox®
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Determination of the effective concentration of oxyteracycline solutions on the inhibition of bioluminescence of Vibrio fischeri (Microtox)
Open Research DataIn this study an attempt was made to determine the effective concentration for oxytetracycline solutions on the inhibition of bioluminescence of Vibrio fischeri (Microtox).
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Dynamic impedance data for various carboxylic acids corrosion inhibition of aluminium in alkaline media (pH=11)
Open Research DataThis dataset contains the results of Dynamic Electrochemical Impedance Spectroscopy (DEIS) carried out in galvanostatic mode under iDC=0, carried out in order to define the corrosion inhibition effect of various studied carboxylic acids: citric acid, malic acid, maleic acid, succinic acid, tartaric acid, carballylic acid, and serine. The experiment...
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X-ray Photoelectron Spectroscopy studies of various carboxylic acids adsorption on aluminium alloys in alkaline media
Open Research DataThis dataset contains the results of high-resolution XPS studies obtained during evaluation of high corrosion inhibition efficiency of various carboxylic acids towards aluminium alloy 5754 in bicarbonate buffer pH=11.
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Effect of new bisacridines IKE16, IKE18 and IE10 on the yeast topoisomerase II relaxation activity
Open Research DataThe datasets contain the results of new bisacridines IKE16, IKE18 and IE10 inhibition activity against yeast topoisomerase II. DNA topoisomerases (Topo) are enzymes that catalyze changes in the spatial structure of DNA and play an important role in replication, transcription and recombination. Beyond their normal functions, DNA topo are significant...
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Determination of the effective concentration of ketoprofen against the germination of Sorghum bicolor (sorghum) seeds
Open Research DataResearch data includes an attempt to determine the effective concentration of ketoprofen that inhibits germination of Sorghum bicolor (sorghum) seeds.
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X-ray Photoelectron Spectroscopy studies of citric acid adsorption on aluminium alloy 5754 in alkaline media
Open Research DataThis dataset contains the results of high-resolution XPS obtained during evaluation of high corrosion inhibition efficiency of citric acid towards aluminium alloy 5754 in bicarbonate buffer pH=11. The exposition duration of samples to electrolytic environment was 100 min. Each sample was exposed at different citric acid concentration ranging from 0...
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IKE1-IKE3 (C-1305 derivatives) inhibitory effect of the Yeast Topoisomerase II relaxation activity
Open Research DataInhibition of Yeast Topoisomerase II were analyzed according to relaxation assay kit from Inspiralis. Briefly, 250 ng of supercoiled pBR322 DNA, 1 mM ATP, 1-200 μM of analyzed compound were mixed with reaction buffer (1 mM Tris-HCl (pH 7.9), 10 mM KCl, 0.5 mM MgCl 2, 0.2 % (v/v) glycerol). The reaction was initiated by the addition of an enzyme, allowed...
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Effect of antitumor compounds on the yeast topoisomerase II relaxation activity
Open Research DataThe datasets contain results of antitumor compounds* (known inhibitors of human topoisomerase alpha II) inhibitory activity against yeast topoisomerase II. DNA topoisomerases (Topo) are enzymes that catalyze changes in the spatial structure of DNA and play an important role in replication, transcription and recombination. Beyond their normal functions,...
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AFM visualization of Mg alloy surface modification
Open Research DataMagnesium alloys with additives improving their mechanical properties are valued as materials with low density and elasticity coefficient. Additionally, their biocompatibility and biodegradability make them interesting in prosthetic applications. However, the last of these features, valuable in medicine, contradicts the industrial needs for the described...
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Impact of binary mixtures of ketoprofen and chloramphenicol on the germination of Sorghum bicolor (sorgo) seeds
Open Research DataResearch was carried out for various ratios of the previously determined EC50 values for mixture of ketoprofen and chloramphenicol, the first substance at 100% of its EC50 concentration was mixed with the second substance at 100% of its EC50 concentration, or the first substance at 50% of its EC50 concentration was mixed with the second substance at...
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Impact of binary mixtures of ketoprofen and diclofenac on the germination of Sorghum bicolor (sorgo) seeds
Open Research DataResearch was carried out for various ratios of the previously determined EC50 values for mixture of ketoprofen and diclofenac, the first substance at 100% of its EC50 concentration was mixed with the second substance at 100% of its EC50 concentration, or the first substance at 50% of its EC50 concentration was mixed with the second substance at 150%...
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Impact of binary mixtures of ketoprofen and oxytetracycline on the germination of Sorghum bicolor (sorgo) seeds
Open Research DataResearch was carried out for various ratios of the previously determined EC50 values for mixture of ketoprofen and oxytetracycline the first substance at 100% of its EC50 concentration was mixed with the second substance at 100% of its EC50 concentration, or the first substance at 50% of its EC50 concentration was mixed with the second substance at...
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AFM images of the platinum (111) single crystal surface as delivered, without the polishing treatment
Open Research DataPlatinum (111) single crystal surface images as delivered, without polishing treatment. Topographic measurements in contact mode. NTEGRA Prima (NT-MDT) device. CSG probe 10.
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Polyacrylamide substrate viscosity impact on temozolomide activity in glioblastoma cells by flow cytometry and rheological measurements
Open Research DataDataset includes raw data on cell lines LN-229 and LN-18 treated with temozolomide measured by flow cytometry, rheometry and cell projections. It also includes calculations necessary for creation of figures and conclusions based on those figures in the publication titiled: "Substrate viscosity impairs temozolomide-mediated inhibition of glioblastoma...
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The mechanism of internalization study of QDgreen−CD−FA−C−2028 conjugate at IC80 value to cancer (H460, Du-145, and LNCaP) and normal (MRC-5 and PNT1A) cells
Open Research DataThe influence of different endocytosis inhibitors on the internalization of QDgreen−CD−FA−C−2028 conjugate at IC80 value in cancer (H460, Du-145, and LNCaP) and normal (MRC-5 and PNT1A) cells. First, the cells were preincubated with: drug-free medium (no inhibitor), at 4 °C, 5 µM Cytochalasin D, 30 µM Amiloride, 80 µM Dynasore, 25 µM Pitstop 2 and 1.5...