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Search results for: PARKINSON DISEASE
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Needs assessment study of rare diseases education for nurses and nursing students in Poland
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Loop-mediated isothermal amplification (LAMP) as a diagnostic tool in detection of infectious diseases
PublicationLoop-mediated isothermal amplification (LAMP) is a gene amplification method which amplifies DNA with high specificity and efficiency under isothermal conditions. Because of its rapidity and simplicity, it is a valuable diagnostic tool in the early detection and identification of infectious diseases. LAMP method is based on the use of a set of four to six specially designed primers spanning six to eight distinct sequences on the...
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Characteristic profiles of DNA epigenetic modifications in colon cancer and its predisposing conditions—benign adenomas and inflammatory bowel disease
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Tax Policy Tools of Selected European Countries as a Mechanism for Counteracting the Effects of the Crisis Caused by the COVID-19 Disease Pandemic
PublicationCrises play an important role in a economics life. They are common and it is impossible to omit them. This following study investigates the concept of ‘crisis’ in the context of economic situation. This text describes the most important financial crises that took place in the past. After that authors passes on a detailed analysis of the actual corona-crisis and the way that it affects the economy globally. The main goal of this...
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Application of Wavelet Transform and Fractal Analysis for Esophageal pH-Metry to Determine a New Method to Diagnose Gastroesophageal Reflux Disease
PublicationIn this paper, a new method for analysing gastroesophageal reflux disease (GERD) is shown. This novel method uses wavelet transform (WT) and wavelet-based fractal analysis (WBFA) on esophageal pH-metry measurements. The esophageal pH-metry is an important diagnostic tool supporting the physician’s work in diagnosing some forms of reflux diseases. Interpreting the results of 24-h pH-metry monitoring is time-consuming, and the conclusions...
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Angiotensin converting enzyme gene polymorphism is associated with severity of coronary artery disease in men with high total cholesterol levels
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Detection of specific UL49 sequences of Marek's disease virus CVI988/Rispens strain using loop-mediated isothermal amplification
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Euthyroid sick syndrome as a prognostic indicator of COVID-19 pulmonary involvement, associated with poorer disease prognosis and increased mortality
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Comparison of the effects of rosuvastatin monotherapy and atorvastatin-ezetimibe combined therapy on the structure of erythrocyte membranes in patients with coronary artery disease
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A pilot study with flow mediated skin fluorescence: A novel device to assess microvascular endothelial function in coronary artery disease
PublicationBackground: Endothelial dysfunction is one of the earliest vascular manifestations in the pathogenesis of cardiovascular disease. Noninvasive, simple and inexpensive methods of endothelial function assessment are therefore needed. Methods: Microvascular endothelial function was assessed in coronary artery disease (CAD) patients by flow mediated skin fluorescence (FMSF), based on measurements of NADH fluorescence intensity during...
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Wireless Body Area Network for Preventing Self-Inoculation Transmission of Respiratory Viral Diseases
PublicationThis paper proposes an idea of Wireless Body Area Networks (WBANs) based on Bluetooth Low-Energy (BLE) standards to recognize and alarm a gesture of touching the face, and in effect, to prevent self-inoculation of respiratory viral diseases, such as COVID-19 or influenza A, B, or C. The proposed network comprises wireless modules placed in bracelets and a necklace. It relies on the received signal strength indicator (RSSI) measurements...
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Application of Navigated Ultrasound for Assessment of the Anterior Pelvic Plane in Patients With Degenerative Hip Diseases
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Myeloperoxidase Modulates Inflammation in Generalized Pustular Psoriasis and Additional Rare Pustular Skin Diseases
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Ultra-rare ultra-care: Assessing the impact of caring for children with ultra rare diseases
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Medical students' knowledge and opinions about rare diseases: A case study from Poland
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A new approach to modeling of selected human respiratory system diseases, directed to computer simulations
PublicationThis paper presents a new versatile approach to model severe human respiratory diseases via computer simulation. The proposed approach enables one to predict the time histories of various diseases via information accessible in medical publications. This knowledge is useful to bioengineers involved in the design and construction of medical devices that are employed for monitoring of respiratory condition. The approach provides the...
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Barriers to the Development of Creative Industries in Culturally Diverse Region
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BRCA1 Loss Preexisting in Small Subpopulations of Prostate Cancer Is Associated with Advanced Disease and Metastatic Spread to Lymph Nodes and Peripheral Blood
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First-Phase Left Ventricular Ejection Fraction as an Early Sign of Left Ventricular Dysfunction in Patients with Stable Coronary Artery Disease
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Design, synthesis and biological evaluation of novel N-phosphorylated and O-phosphorylated tacrine derivatives as potential drugs against Alzheimer’s disease
PublicationIn this work, we designed, synthesised and biologically investigated a novel series of 14N- and O-phosphorylated tacrine derivatives as potential anti-Alzheimer’s disease agents. In the reaction of 9-chlorotacrine and corresponding diamines/aminoalkylalcohol we obtained diamino and aminoalkylhydroxy tacrine derivatives. Next, the compounds were acid to give final products 6–13 and 16–21 that were characterised by 1H, 13 C, 31P...
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Acceptance of a potential major bleeding among patients with venous thromboembolism on long-term oral anticoagulation: the knowledge of the disease and therapy matters
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Angiogenina - nowy kierunek badań w chorobie niedokrwiennej serca? = Angiogenin - new important parameter in the assessment of ischaemic heart disease?
PublicationAngiogenezę można zdefiniować jako proces prowadzący do powstawania nowych naczyń z już istniejących, poprzez ich rozgałęzianie i wydłużanie. Z klinicznego punktu widzeniaiedza o angiogeninie jest niezwykle cennna z co najmniej dwóch powodów. Może dostarczyć informacji o tworzącym się, bardzo pożądanym krążeniu obocznym w mięśniu sercowym, a także może w przyszłości odegrać istotną rolę w leczeniu nowotworów, zapalenia stawów,...
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Activity ofα1-Antitrypsin and Some Lysosomal Enzymes in the Blood Serum of Patients with Chronic Obstructive Pulmonary Disease after Smoking Cessation
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Glucosylceramide Mimics: Highly Potent GCase Inhibitors and Selective Pharmacological Chaperones for Mutations Associated with Types 1 and 2 Gaucher Disease
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The influence of statin monotherapy and statin-ezetimibe combined therapy on FoxP3 and IL 10 mRNA expression in patients with coronary artery disease
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Therapeutic biomaterials - application in neurology and cardiology
PublicationBiomaterials are of interest in most medical fields. It's hard to imagine life without them. And due to the ever-increasing demand, scientists are developing new materials. Diseases of the nervous and cardiovascular systems are still a big problem, which are associated with a limited ability to regenerate brain or heart tissues. Therefore, this review discusses the advancement in biomaterial engineering for the treatment of neurological...
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Therapeutic biomaterials – application in neurology and cardiology
PublicationBiomaterials are of interest in most medical fields. It's hard to imagine life without them. And due to the ever-increasing demand, scientists are developing new materials. Diseases of the nervous and cardiovascular systems are still a big problem, which are associated with a limited ability to regenerate brain or heart tissues. Therefore, this review discusses the advancement in biomaterial engineering for the treatment of neurological...
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Awareness of patients suffering from selected chronic diseases of the importance of physical activity in treating their disorders
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Public Perception of the Risks Associated with Infectious Diseases in Poland: Ebola and Influenza and Their Impact on the Attitude to Vaccination
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Psychological Functioning of Women Diagnosed with Lichen Planus and Other Diseases of the Oral Cavity—Explorative Study
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Selected Psychosocial Factors, Nutritional Behavior, and the Analysis of Concentrations of Selected Vitamins in Patients with Cardiovascular Diseases
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Iranian future healthcare professionals' knowledge and opinions about rare diseases: cross-sectional study
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Iranian future healthcare professionals’ knowledge and opinions about rare diseases: cross‑sectional study
PublicationBackground: Rare diseases are a new global health priority, requiring evidence-based estimates of the global prevalenceof diseases to inform public policymakers and provide a serious challenge to the healthcare system that must not be ignored. The purpose of this study is to investigate Iranian future healthcare professionals’ knowledge and opinions about rare diseases.Results: A total of 6838 students responded...
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The Awareness of Rare Diseases Among Medical Students and Practicing Physicians in the Republic of Kazakhstan. An Exploratory Study
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Neural Graph Collaborative Filtering: Analysis of Possibilities on Diverse Datasets
PublicationThis paper continues the work by Wang et al. [17]. Its goal is to verify the robustness of the NGCF (Neural Graph Collaborative Filtering) technique by assessing its ability to generalize across different datasets. To achieve this, we first replicated the experiments conducted by Wang et al. [17] to ensure that their replication package is functional. We received sligthly better results for ndcg@20 and somewhat poorer results for...
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Neural Graph Collaborative Filtering: Analysis of Possibilities on Diverse Datasets
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Endothelial function and baroreflex sensitivity according to the oral glucose tolerance test in patients with coronary artery disease and normal fasting glucose levels
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Molecularly targeted nanoparticles: an emerging tool for evaluation of expression of the receptor for advanced glycation end products in a murine model of peripheral artery disease
PublicationAbstract Background: Molecular imaging with molecularly targeted probes is a powerful tool for studying the spatio-temporal interactions between complex biological processes. The pivotal role of the receptor for advanced glycation end products (RAGE) in numerous pathological processes, aroused the demand for RAGE targeted imaging in various diseases. In the study, we evaluated the use of a diagnostic imaging agent for RAGE quantification...
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Impact of abdominal obesity on the frequency of hypertension and cardiovascular disease in Poland – Results from the IDEA study (International Day for the Evaluation of Abdominal Obesity)
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Does abdominal obesity have a similar impact on cardiovascular disease and diabetes? A study of 91 246 ambulant patients in 27 European Countries
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Outcome and prognostic factors in advanced Hodgkin's disease treated with high-dose chemotherapy and autologous stem cell transplantation: a study of 341 patients
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Interactions between Marek’s disease virus Rispens/CVI988 vaccine strain and adenovirus field strain in chicken embryo fibroblast (CEF) cultures
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ENHANCED DISEASE SUSCEPTIBILITY 1 (EDS1) affects development, photosynthesis, and hormonal homeostasis in hybrid aspen ( Populus tremula L. × P. tremuloides )
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Cross-domain applications of multimodal human-computer interfaces
PublicationDeveloped multimodal interfaces for education applications and for disabled people are presented, including interactive electronic whiteboard based on video image analysis, application for controlling computers with mouth gestures and audio interface for speech stretching for hearing impaired and stuttering people and intelligent pen allowing for diagnosing and ameliorating developmental dyslexia. The eye-gaze tracking system named...
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Therapeutic Potential of Multifunctional Tacrine Analogues
PublicationTacrine is a potent inhibitor of cholinesterases (acetylcholinesterase and butyrylcholinesterase) that shows limiting clinical application by liver toxicity. In spite of this, analogues of tacrine are considered as a model inhibitor of cholinesterases in the therapy of Alzheimer’s disease. The interest in these compounds is mainly related to a high variety of their structure and biological properties. In the present review, we...
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In vivo evidence of ascorbate involvement in the generation of epigenetic DNA modifications in leukocytes from patients with colorectal carcinoma, benign adenoma and inflammatory bowel disease
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Psychological burden and disease-related quality of life in dialysis patients during the first wave of the COVID-19 pandemic — a cross-sectional observational study
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Editorial: Coronavirus disease (COVID-19): Socio-economic systems in the post-pandemic world: Design thinking, strategic planning, management, and public policy
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Reactivity of triphosphinoboranes towards H3B·SMe2: access to derivatives of boraphosphacycloalkanes with diverse substituents
PublicationTriphosphinoboranes activated the B–H bond in the BH3 molecule without any catalysts at room temperature. Hydroboration reactions led to boraphosphacyloalkanes with diverse structures. The outcomes of reactions depend on the size of the phosphanyl substituent on the boron atom of the parent triphosphinoborane, where derivatives of boraphosphacyclobutane and boraphosphacyclohexane were obtained. Furthermore, the precursor of triphosphinoboranes,...
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Middle Eastern Christian Spaces in Europe: Multi-sited and Super-diverse
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