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Search results for: metabolic syndrome
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Disturbances of magnetic field in surrounding of mobile, metalic plate
PublicationThe uniform magnetic field of the Earth in the surrounding of a mobile, metalic object undergoes deformation by eddy currents. The influence of the moving conducting object on total magnetic field of the Earth depends on the object's shape, position and speed of the changes relative to the magnetic field's vector of the Earth as well as the electric conductivity and the relative magnetic permeability of the material. The disturbances...
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Lactose and β-Glucosides Metabolism and Its Regulation in Lactococcus lactis: A Review
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Vitamin D Metabolism Gene Polymorphisms and Their Associated Disorders: A Literature Review
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Activities of genes controlling sphingolipid metabolism in human fibroblasts treated with flavonoids
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Modulation of expression of genes involved in glycosaminoglycan metabolism and lysosome biogenesis by flavonoids
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Ascorbate and glutathione metabolism in embryo axes and cotyledons of germinating lupine seeds
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Completing Autophagy: Formation and Degradation of the Autophagic Body and Metabolite Salvage in Plants
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Evaluation of bioconcentration and metabolism of diclofenac in mussels Mytilus trossulus - laboratory study
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Urinary metabolomic signature of muscle-invasive bladder cancer: A multiplatform approach
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Central carbon metabolism influences fidelity of DNA replication in Escherichia coli
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The II phase metabolism of endogenous and exogenous compounds, including antitumor chemotherapeutics
PublicationThe II phase metabolism, it is a set of metabolism and excretion pathways of endogenous as well as exogenous compounds including xenobiotics. UDP-glucuronyltransferases (UGTs; EC 2.4.1.17) are the most crucial representatives of II phase enzymes, which are responsible for the transformation of bilirubine and bile acids, steroids and thyroid hormones and lipids. Exogenous compounds, including drugs, carcinogens, environmental pollutants...
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The Impact of Different Drying Methods on the Metabolomic and Lipidomic Profiles of Arthrospira platensis
PublicationDrying is an inseparable part of industrial microalgae production. In this work, the impacts of eight different drying methods on the metabolome and lipidome of Arthrospira platensis were investigated. The studied drying methods were freeze drying (FD), sun drying (SD), air drying at 40 and 75 °C (AD′ and AD″), infrared drying at 40 and 75 °C (IRD′ and IRD″), and vacuum drying at 40 and 75 °C (VD′ and VD″). Results gathered by...
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Renal Regulation of Calcium-Phosphate Metabolism in Single- and Twin Pregnant Goats
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Metabolic Profiling of Jasminum grandiflorum L. Flowers and Protective Role against Cisplatin-Induced Nephrotoxicity: Network Pharmacology and In Vivo Validation
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NADPH-Cytochrome P-450 reductase in strongly involved in activating metabolic transformatios of 9-amino-1-nitroacridine antitumor agents
PublicationCelem pracy było wyjaśnienie roli reduktazy cytochromu P-450 jaką odgrywa ten enzym w przemianach metabolicznych dwóch związków przeciwnowotworowych z grupy pochodnych 1-nitroakrydyny. Zastosowano metodę HPLC do rozdziału metabolitów, a badania struktur przeprowadzono stosując metodę ESI-MS. Wykazano, że badana reduktaza jest zaangażowana bardziej w metabolizm aktywacyjny 1-nitroakrydyn niż metabolizm detoksykacyjny.
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Hypericum alpestre extract exhibits in vitro and in vivo anticancer properties by regulating the cellular antioxidant system and metabolic pathway of L‐arginine
PublicationConventional treatment methods are not effective enough to fight the rapid increase in cancer cases. The interest is increasing in the investigation of herbal sources for the development of new anticancer therapeutics. This study aims to investigate the antitumor capacity of Hypericum alpestre (H. alpestre) extract in vitro and in vivo, either alone or in combination with the inhibitors of the L‐arginine/polyamine/nitric oxide...
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The Peritoneal Neovagina after Davydov's Laparoscopic Procedure in Mayer-Rokitansky-Küster-Hauser Syndrome: Morphology and Ultrastructure Investigation of the New Epithelium
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Approach to a child with Multisystem Inflammatory Syndrome associated with COVID19. Recommendations by the Polish Paediatric Society Expert Group. Update – February 2021
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Effect of exercise training on insulin sensitivity, mitochondria and computed tomography muscle attenuation in overweight women with and without polycystic ovary syndrome
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Vascular endothelial growth factor (VEGF-C1)-dependent inflammatory response of podocytes in nephrotic syndrome glomerulopathies in children: an immunohistochemical approach
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Effect of beta-blocker therapy on heart rate response in patients with hypertension and newly diagnosed untreated obstructive sleep apnea syndrome
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Phase I and phase II metabolism simulation of antitumor-active 2-hydroxyacridinone with electrochemistry coupled on-line with mass spectrometry.
PublicationHere, we report the metabolic profile and the results of associated metabolic studies of 2-hydroxyacridinone (2-OH-AC), the reference compound for antitumor-active imidazo- and triazoloacridinones. Electrochemistry coupled with mass spectrometry was applied to simulate the general oxidative metabolism of 2-OH-AC for the first time. The reactivity of 2-OH-AC products to biomolecules was also examined. The usefulness of the electrochemistry...
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Surface roughness of ceramic parts after lapping by abrasive-metallic tools
PublicationPrzedstawiono konstrukcję narzędzi ścierno-metalowych do obróbki na docierarce jednotarczowej. Wykonano badania docierania elementów z ceramiki tlenowej. Analizowano podstawowe parametry chropowatości powierzchni elementów z Al2O3 po obróbce narzędziami na bazie węglika boru.
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An Experimental Study on the Effect of Temperature on Acoustic Emission Characteristics in Metallic Structures
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Laser Surface Alloying of Aluminium Alloys with Cu/Fe Metallic Powders
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Low-Profile Interdigitated UHF RFID Tag Antenna for Metallic Objects
PublicationThis article presents a novel miniature interdigitated ultra-high frequency (UHF) radio frequency identification (RFID) tag antenna that can be placed on metallic objects. The tag structure comprises two horizontal strip lines, each loaded with seven identical open stubs, and an integrated circuit (IC) chip connected directly to the feed lines in the middle of the structure. The perfect match to the IC chip’s impedance is realized...
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ABSORPCJA, METABOLIZM I ROLA BIOLOGICZNA KWASÓW NUKLEINOWYCH OBECNYCH W ŻYWNOŚCI
PublicationKwasy nukleinowe należą do niedocenianych składników żywności, szczególnie surowej lub nisko przetworzonej. W niniejszej publikacji skupiono się na omówieniu przemian, jakim podlegają kwasy nukleinowe w przewodzie pokarmowym człowieka, procesie absorpcji nukleotydów oraz nukleozydów z przewodu pokarmowego, a także przedstawiono podstawowe etapy ich metabolizmu w komórkach organizmu. Produkty trawienia kwasów nukleinowych stanowią...
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ClaR—a novel key regulator of cellobiose and lactose metabolism in Lactococcus lactis IL1403
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Metabolism of Tryptophan and Depressive Symptoms Six Months after Interferon- alfa Treatment
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Research Trends of Vitamin D Metabolism Gene Polymorphisms Based on a Bibliometric Investigation
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Erratum to: Activities of genes controlling sphingolipid metabolism in human fibroblasts treated with flavonoids
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The Phytoestrogen Genistein Modulates Lysosomal Metabolism and Transcription Factor EB (TFEB) Activation
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Caffeine Inhibits Differentiation Of Lung Cancer Stem Cells By Modulating Their Respiratory Metabolism
PublicationIt is ell established that many tumor types contain a fraction of cells, with stem cell-like properties, called cancer stem cells (CSCs), that are resistant to apoptosis induced by therapeutic agents. The presence of CSCs may explain why a standard anticancer treatment, that eliminates only differentiated cancer cells, does not lead to cancer cure.We previously showed the existence of caffeine-sensitive mechanism that controls...
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Effects of Single and Repeated Footshock on Dopamine Release and Metabolism in the Brains of Fischer Rats
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New supervised alignment method as a preprocessing tool for chromatographic data in metabolomic studies
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Uptake, tissue distribution, and metabolism of malachite green in the channel catfish (Ictalurus punctatus)
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The Influence of Hydrodynamic Conditions in a Laboratory-Scale Bioreactor on Pseudomonas aeruginosa Metabolite Production
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Cytochromes P-450: specyfic enzymes involved in metabolism of endogenous substances and xenobiotics
PublicationCytochromy P-450 to grupa enzymów hemoproteinowych występujących w prawie wszystkich organizmach żywych. Substratami tych enzymów są zarówno substancje endogenne jak i ksenobiotyki, włączając w to leki, dodatki do żywności oraz zanieczyszczenia środowiska. W pracy omówiono rolę polimorfizmu oraz indukcji P-450 w metabolizmie leków przeciwnowotworowych.
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Metabolic activity of tree saps of different origin towards cultured human cells in the light of grade correspondence analysis and multiple regression modeling
PublicationTree saps are nourishing biological media commonly used for beverage and syrup production. Although the nutritional aspect of tree saps is widely acknowledged, the exact relationship between the sap composition, origin, and effect on the metabolic rate of human cells is still elusive. Thus, we collected saps from seven different tree species and conducted composition-activity analysis. Saps from trees of Betulaceae, but not from...
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Analysis of 21 appendices from children with multisystem inflammatory syndrome compared to specimens of acute appendicitis – a new insight into MIS-C pathology
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Rehabilitacja dzieci autystycznych oraz z zespołem Downa a poczucie obciążenia opiekunów / Rehabilitation of children with Down Syndrome and autism, and caregivers burden
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The Role of GLP-1, GIP, MCP-1 and IGFBP-7 Biomarkers in the Development of Metabolic Disorders: A Review and Predictive Analysis in the Context of Diabetes and Obesity
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New Gene Markers for Metabolic Processes and Homeostasis in Porcine Buccal Pouch Mucosa during Cells Long Term-Cultivation—A Primary Culture Approach
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Comparative Analysis of Metabolic Variations, Antioxidant Profiles and Antimicrobial Activity of Salvia hispanica (Chia) Seed, Sprout, Leaf, Flower, Root and Herb Extracts
PublicationThe purpose of this study was to evaluate the phytochemical profiles of the seeds, sprouts, leaves, flowers, roots and herb of Salvia hispanica and to demonstrate their significant contribution to antioxidant and antimicrobial activities. Applied methods were: HPLC-DAD coupled with post-column derivatization with ABTS reagent, untargeted metabolomics performed by LC-Q-Orbitrap HRMS, and two-fold micro-dilution broth method, which...
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Novel 2-alkythio-4-chloro-N-[imino(heteroaryl)methyl]benzenesulfonamide Derivatives: Synthesis, Molecular Structure, Anticancer Activity and Metabolic Stability
PublicationA series of novel 2-alkythio-4-chloro-N-[imino-(heteroaryl)methyl]benzenesulfonamide derivatives, 8–24, were synthesized in the reaction of the N-(benzenesulfonyl)cyanamide potassium salts 1–7 with the appropriate mercaptoheterocycles. All the synthesized compounds were evaluated for their anticancer activity in HeLa, HCT-116 and MCF-7 cell lines. The most promising compounds, 11–13, molecular hybrids containing benzenesulfonamide...
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Magnetotransport Properties of Semi-Metallic Bismuth Thin Films for Flexible Sensor Applications
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Superconducting state in the atomic metallic hydrogen just above the pressure of the molecular dissociation
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FINITE GROUND CPW-FED UWB ANTENNA OVER THE METALLIC CYLINDRICAL SURFACES
PublicationThe investigation of finite ground coplanar fed ultra-wideband (UWB) antenna and the influence of its curvature and the proximity of circular metallic screen on the reflection coefficients and radiation characteristics is presented. The antenna is composed of two circular coplanar strips which enclose slot aperture of similar shape and is designed on a thin and flexible substrate which allows its bending. The antenna configuration...
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Photostability pf Cy3 and Cy5-labeled DNA in the presence of metallic silver particles
PublicationZbadano wpływ cząstek metalicznego srebra na fotostabilność oligomerów DNA kowalencyjnie związanych z Cy3 lub Cy5. Zbliżenie fluoroforów do cząstek srebra powodowało zwiększenie intensywności fluorescencji i pojawienie się frakcji emisji bardziej odpornej na wybielanie.
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Gel-based separation of single-walled carbon nanotubes for metallic and semiconducting fractions
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