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Search results for: HERNIA REPAIR
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EXPERIMENTS AND SIMULATIONS FOR LAPAROSCOPICVENTRAL HERNIA REPAIR IMPROVEMENT
PublicationThe authors conducted a wide experimental and numerical study in order to determine effective approaches in the laparoscopic VH repair. At first the study covered identification of mechanical properties of the abdominal fascia, implants, tacks and transabdominalsutures. Basis on these data, the one and two-dimensional mathematical models were formulated and a number of numerical static and dynamic analyses were carried out. Then...
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Mechanical properties of mosquito nets in the context of hernia repair
PublicationThe paper deals with issue of applying mosquito nets as implants in hernia repair, which have already been used in resource-poor developing countries. Uniaxial tensile tests have been conducted on polyester mosquito meshes in two orthogonal directions. Non-linear elastic constitutive laws parameters have been identified to be applied in dense net material models. Mechanical performance of tested mosquito nets has been compared...
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Two-criteria optimisation problem for ventral hernia repair
PublicationTwo-criteria optimisation problem related to laparoscopic ventral hernia repair is formulated in this paper. An optimal implant from a given set and its orientation is sought. The implant is subjected to kinematic extortions due to a patient’s body movement and intra-abdominal pressure. The first criterion of the optimisation problem deals with the reaction force in the implant fastener, while the deflection of the implant constitutes...
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Mechanical compatibility of implants used in hernia repair with abdominal wall
PublicationThe paper deals with a membrane model of a synthetic surgical mesh for treatment of abdominal hernia. The authors analyse the compatibility of two implant types with the human wall: Dualmesh Gore and Proceed. The finite element method is applied to simulate tjhe behavior of the proposed model. Due fact that recurrences are usually caused by connection failure, this study is focused on reaction forces in supports representing the...
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Assessment of usefulness of different tacks in laparoscopic ventral hernia repair
PublicationLaparoscopic ventral hernia repair is becoming a popular technique with good results and fast postoperative recovery. The mesh is placed directly under the peritoneum and anchored with transabdominal sutures and tacks. However, the ideal size of the mesh covering the hernia orifice is know, nor the ideal type or amount of tacks has to be described.
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Paraesophageal Hernia Repair Followed by Cardiac Tamponade Caused by ProTacks
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SIMULATION OF PROCEED® SURGICAL MESH APPLIED TO VENTRAL HERNIA REPAIR
PublicationIn the present research, Proceed® implant is considered. The system is subjected to short-time dynamic pressure load, similar to post-operative cough naturally occurring in human abdomen. The model refers to a clinical case of 5cm of hernia operated by Proceed implant fixed by 15 joints every 3cm around the orifice. The simulations of the implanted mesh are performed by means of the Finite Element Method. The implant is modelled...
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Mechanical Modelling of Human Fascia in the Problem of Ventral Hernia Repair
PublicationPraca dotyczy badań doświadczalnych tkanki ludzkiej oraz symulacji numerycznej zachowania tej tkanki. Na podstawie eksperymentu dokonuje się identyfikacji modelu materiałowego tkanki a następnie w celu wweryfikacji przeprowadza się symulacje numeryczną zachowania modelowanej struktury. Celem badań jest uzyskanie informacji przydatnych podczas leczenia przepuklin brzusznych u ludzi.
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Mathematical modelling of implant in an operated hernia for estimation of the repair persistence
PublicationThis paper presents mathematical modelling of an implanted surgical mesh used in the repair process of the abdominal hernia. The synthetic implant is simulated by a membrane structure. The author provides a material modelling of the implant based on the dense net model appropriate for technical fabrics. The accuracy of the proposed solution is evaluated by comparing the simulations of the dynamic behaviour of the system with the...
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Orthotropic membrane as a mechanical model of surgical implant in abdominal hernia repair
PublicationEven though the incisional hernia repair surgery is a well known procedure, mechanical properties of the tissue-implant system are unknown so the implantation of the repairing mesh is quite intuitive and, recurrences of the illness still take place. The main objective of the study is to define an operated hernia model that can be used for surgery planning and the assessment of the repair persistence. The load applied to the structure...
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Dynamics of mechanical model of implant-tissue system in ventral hernia repair
PublicationThe paper deals with a finite element modelling of implants in the problem of ventral hernia repair. The synthetic mesh implanted in the abdomen during surgery is here modelled as a membrane structure. Thesystem undergoes the internal abdominal pressure that occurs during the postoperative cough, the load identified in the literature as the main cause of the connection failure and hernia recurrence. The model can be used to estimate...
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IMPLANT USED IN HERNIA REPAIR UNDER PHYSIOLOGICAL MOVEMENTS OF HUMAN ABDOMEN
PublicationThe study deals with the mechanical behaviour of implant used in repair of abdominal hernia. The influence of orientation of the orthotropic implants in different areas of abdominal wall is studied.
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In vivo performance of intraperitoneal onlay mesh after ventral hernia repair
PublicationBackground: Ventral hernia repair needs to be improved since recurrence, postoperative pain and other complications are still reported in many patients. The behavior of implants in vivo is not sufficiently understood to design a surgical mesh mechanically compatible with the human abdominal wall. Methods: This analysis was based on radiological pictures of patients who underwent laparoscopic ventral hernia repair. The pictures...
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Cough influence on fascia-mesh system built for a hernia repair - an experimental research
PublicationAn experimental approach to identify stronger and weaker fixation schemes in laparoscopic ventral hernia repair is presented in the paper. Two types of implants, whose mechanical properties are significantly different and five kinds of connectors are considered. Physical models of operated hernia have been built using those materials and porcine abdominal tissue. The models have been subjected to dynamic impulse load, similar to...
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Mechanical behaviour of the implant used in human hernia repair under physiological loads
PublicationIn laparoscopic operations of abdominal hernias some recurrences still take place, even when applying a surgical mesh. This is usually caused by a failure of the connection between the tissue and the implant. The study deals with the influence of an implant’s orientation on forces in joints, which connect the mesh to human tissues. In the paper, the implant is modelled as a membrane structure within framework of the Finite Element...
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A PRELIMINARY STUDY ON THE OPTIMAL CHOICE OF AN IMPLANT AND ITS ORIENTATION IN VENTRAL HERNIA REPAIR
PublicationThis paper addresses the problem of ventral hernia repair. The main goals are to find an optimal surgical mesh for hernia repair and to define its optimal orientation in the abdominal wall to minimise the maximum force at the tissue-implant juncture. The optimal mesh is chosen from a set of orthotropic meshes with different stiffness ratios for typical hernia placement in the abdominal area. The implant is subjected to an anisotropic...
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Surgical implant used in ventral hernia repair subjected to physiological pressure - computer simulation
PublicationW streszczeniu przedstawiono matemayczny model implantu wszczepionego pacjentowi podczas laparoskopowej naprawy przepukliny brzusznej. Wykonano go z użyciem metody elementów skończonych. Przyjęto ortotropowy model materiałowy implantu.
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Biomechanics of the front abdominal wall as a potential factorleading to recurrence with laparoscopic ventral hernia repair
PublicationThis study investigated the front abdominal wallto describe its elasticity in vivo and searched for elongationsthat possibly stretched an implanted mesh, therebycausing fixation failure and subsequent recurrence.To measure front abdominal wall elongations, amodel of fascia movements was created. Eight healthyvolunteers were measured during exercise to determine theextent of elongations in their front abdominal wall. Videoswere...
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Antibiotic prophylaxis in open inguinal hernia repair: a literature review and summary of current knowledge
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Behaviour of orthotropic surgical implant in hernia repair due to the material orientation and abdomen surface deformation
Publicationrelation to the different range of typical deformations observed in different directions and zones of abdomen surface due to the patients’ life activities, has a significant influence on the extreme junction forces in the mesh–tissue connections and hence the repair persistence. The finite element model of the orthotropic implant was developed, and the junction forces in the connections of tissue and mesh were studied. The kinematical...
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Physical and mathematical modelling of implant-fascia system in order to improve laparoscopic repair of ventral hernia
PublicationThis paper describes an investigation of biomechanical behaviour of hernia repair, which is focused on the selection of safe linking of certain type of implant with fascia in laparoscopic operation. The strength of various fixations of the implant to the fascia is analysed. Methods: The research is based on experimental observations of operated hernia model behaviour during a dynamic impulse load corresponding to post-operative...
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Modeling of the fascia-mesh system and sensitivity analysis of a junction force after a laparoscopic ventral hernia repair
PublicationW pracy rozpatrywano prosty model cięgnowy układu powięż-siatka do oszacowania siły połączenia siatki z powięzią po operacji laparoskopowej przepukliny brzusznej. Cięgno obciążone jest ciśnieniem wewnątrz brzusznym, symulującym kaszel, oraz przemieszczeniami jego końców wywołanymi skłonami pacjenta. Wpływ poszczególnych parametrów cięgna na siłę połączenia określono za pomocą analizy wrażliwości. Sformułowano pewne wnioski ważne...
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Constitutive Modelling of Knitted Abdominal Implants in Numerical Simulations of Repaired Hernia Mechanics
PublicationThe paper presents a numerical approach to describe mechanical behavior of anisotropic textile material, which is a selected abdominal prosthesis. Two constitutive nonlinear concepts are compared. In the first one the material is considered composed from two families of threads (dense net model) and in the second one the material is homogeneous but anisotropic (as proposed by Gassel, Ogden, Holzapfel). Parameters of both models...
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Investigation of abdomen surface deformation due to life excitation: implications for implant selection and orientation in laparoscopic ventral hernia repair
PublicationVentral hernia is a common medical problem. Statistically there are around 10% recurrences of the sickness. The authors' former investigation proved edges of the hernia orifice displacements to be one of the factors causing recurrence. Thus, experimental investigation of the abdomen surface deformation due to some normal activities of people is studied.The extreme strains, their localization and directions are identified. The acquired...
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Safety and efficacy of a Ventralight ST echo ps implant for a laparoscopic ventral hernia repair – a prospective cohort study with a one-year follow-up
Publicationing new products Thus, every mesh prior to introduction in clinical settings should be tested with a dedicated tacker to discover the proper fixation algorithm. The aim of the study was to assess the safety and efficacy of the Ventralight ST implant with an ECHO positioning system and a dedicated fixation device, the SorbaFix stapler, in a prospective cohort of patients. Material and methods. The study was a prospective single...
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6.2, Engineering structures. [Chapter] 6.2.1, Assessment of the technical condition and repairs to cylindrical tank : 6.2.2, Assessment and repair of underground arterial pipelines : 6.2.4, Assessment and repair of steel chimneys
PublicationJerzy Ziółko opracował następujące fragmenty książki: w rozdziale 6.2. Engineering structures (Obiekty inżynierskie), pkt. 6.2.1 Assessment of the technical condition and repairs to cylindrical tank (Diagnostyka stanu technicznego i naprawy zbiorników walcowych), pkt. 6.2.2 Assessment and repair of underground arterial pipelines (Diagnostyka i naprawy podziemnych rurociągów magistralnych, pkt. 6.2.4 Assessment and repair of steel...
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Folding‐upon‐repair DNA nanoswitches for monitoring DNA repair enzymes activity
PublicationWe demonstrate here a new class of DNA‐based nanoswitches that, upon enzymatic repair, could undergo a conformational change mechanism leading to a change in fluorescent signal. Such folding‐upon‐repair DNA nanoswitches are synthetic DNA sequences containing O6‐methyl‐guanine (O6‐MeG) nucleobases and labelled with a fluorophore/quencher optical pair. The nanoswitches are rationally designed so that only upon enzymatic demethylation...
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Development of polyurethanes for bone repair
PublicationThe purpose of this paper is to review recent developments on polyurethanes aimed at the design, synthesis, modifications, and biological properties in the field of bone tissue engineering. Different polyurethane systems are presented and discussed in terms of biodegradation, biocompatibility and bioactivity. A comprehensive discussion is provided of the influence of hard to soft segments ratio, catalysts, stiffness and hydrophilicity...
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Mechanical behaviour of knit synthetic mesh used in hernia surgery
PublicationPurpose: There is a discussion in literature concerning mechanical properties and modelling of surgical meshes. An important feature of elastic modulus dependency on load history is taken into account in this paper, as implants are subjected to variable loading during human activity. The example of DynaMesh®-IPOM surgical implant is studied. Methods: The analysis is based on failure tension tests and cyclic loading and unloading...
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Damage repair of the double shell tank
PublicationPłaszcz wewnętrzny stalowego zbiornika dwupłaszczowego o pojemności 10000 m3 został zdeformowany w wyniku błędu popełnionego podczas próby wodnej przy odbiorze zbiornika. W referacie omówiono technologię naprawy silnie zdeformowanego płaszcza zbiornika. Stosowano roztłaczanie hydrauliczne, prostowanie mechaniczne i termiczne oraz wymianę najbardziej uszkodzonych blach.
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Influence of Polymorphisms in DNA Repair GenesXPD, XRCC1andMGMTon DNA Damage Induced by Gamma Radiation and its Repair in LymphocytesIn Vitro
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Optimization and control of tissue growth and repair in bioreactor.
PublicationPraca przedstawia model matematyczny procesu optymalizacji i odnowy hodowanej w bioreaktorze tkanki. Model matematyczno-numeryczny umożliwia właściwy dobór parametrów w trakcie hodowli w celu uzyskania pożądanych efektów w zakresie fizyko-chemicznych właściwości rozmnażającej się tkanki. Charakterystyką o znamionach nowości jest wieloparametrowość optymalizacji w zakresie hodowli tkanek.
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Common variants of DNA repair genes and malignant melanoma
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A Method Supporting Monitoring And Repair Processes of Information Systems
PublicationW pracy zaproponowano nową metodę (ARM) zarządzania monitorowaniem i naprawą systemów IT, bez przerywania ciągłości ich funkcjonowania. Metoda ta integruje procesy monitorowania (uwzględniając już istniejące i stosowane rozwiązania) z procesami naprawy. Stworzono formalny model koncepcyjny opisujący dziedzinę monitorowania i naprawy oraz formalne specyfikacje mechanizmu napraw oraz wybranych procedur naprawczych. Do specyfikacji...
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Towards automating repairs of IT systems
PublicationThis paper presents formal description of working principles of the repair library, being the essential component of the Repair Management Framework (RMF), which aims at automating the process of repairing IT systems, and consists also of the Repair Management Model (RMM) and the Repair Management System (RMS). RMM introduces two mathematical models (model of monitoring and model of repair processes), general enough to cover the...
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A system automating repairs of IT systems
PublicationThis paper presents two problems that are important nowadays: the problem of IT systems monitoring and the problem of repairing them. It shows the developed solution, aimed to automate the existing industrial repair process and to integrate it with the existing monitoring solutions and mechanisms. Described solution is a part of a bigger whole, called the Repair Management Framework (RMF). This paper presents also briefly a case...
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Towards automation of IT systems repairs
PublicationMonitoring and repair are two sides of the on-the-fly maintenance of IT systems.Monitoring is well supported by automatic tools. In contrast, repairs involve much higherhuman intervention which negatively affects reliability and efficiency. The paper intro-duces a method of automating repairs of IT systems which can be integrated with any ofthe existing monitoring mechanisms. The method is described as a collection of modelsand...
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Experimental Study on Polymer Mass Used to Repair Damaged Structures
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Experimental study on polymer mass used to repair damaged structures
PublicationA new method of repairing damaged structures by injecting the cracks with specially designed polymer mass (flexible two-component grout based on polyurethane resin) has been recently proposed. The technique is mainly dedicated to damaged masonries, especially historical structures where minimum intervention is permitted. The cracks are filled with the special injection, forming the flexible joints bonding the disrupted structural...
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MutL protein as a constituent of vsp, ner and mmr repair systems
PublicationMutS and MutL proteins are renowned mostly for their functions in well-characterized, post-DNA replication mis- match repair system (MMR). However, there is growing evidence that MMR system is not the only field of action for these pro- teins. Moreover, the participation in MMR does not even have to be their primary function. There are some reports indicat- ing involvement of MutL in BER, NER and VSP (very short patch repair)....
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Towards Understanding of Mechanics of Hernia Managed by Synthetic Mesh in Laparoscopic Operation: A Single Case Study
PublicationIn this paper a research towards understanding of mechanics of ventral hernia operated with the use of Physiomesh Open image in new window implant and SecureStrap Open image in new window staples is described. Experimental and numerical studies are conducted for that purpose. Experimental works cover uni-axial tension tests of the implant samples and of the implant-staples-tissue system. Also experiments on implant-staples-tissue...
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Safety assessment of a concrete viaduct damaged by vehicle impact and an evaluation of the repair
PublicationDamage to lower parts of viaducts caused by impact from under-passing high vehicles is relatively frequent. One such incident, in which a viaduct was damaged by the impact from a truck with an improperly assembled hydraulic crane, is considered in this work. The analysis is based on a detailed object damage evaluation, 3D laser scanning, and numerical simulations. The aim of the study is to accurately model the vehicle impact into...
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DNA repair is responsible for the presence of oxidatively damaged DNA lesions in urine
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Underwater Wet Repair Welding of API 5L X65M Pipeline Steel
PublicationThis paper presents results of the research of effect of polymer insulation of pipeline made of API 5L X65M steel as well as underwater wet welding parameters on properties of joints made by covered electrodes. Effect of heat input on structure and hardness of joints during repair of underwater pipeline was analyzed. Welding defects like microcracks, micro-lacks of fusion, slag inclusions, as well as HAZ hardness increase over...
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A FEM membrane model of human fascia-synthetic implant system in a case of a stiff ventral hernia orifice
PublicationPraca prezdstawia model matematyczny układu tkanka ludzka - implant syntetyczny w postaci tzw. siatki w leczeniu przepuklin brzusznych. Implant jest tu moelowany jako struktura membranowa. Ocena wpływu danych materiałowych oraz wstępnego napięcia na zachowanie pracującej membrany po implantacji została przedstawiona na podstawie analizy wrażliwości. Pracę podsumowują pewne wskazówki dla chirurgów implantujących siatki.
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Polymorphisms in nucleotide excision repair genes and susceptibility to colorectal cancer in the Polish population
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Conservative surgical repair in cervical atresia associated with partial or complete absence of the vagina
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Mechanism for Repair of Thymine Dimers by Photoexcitation of Proximal 8-Oxo-7,8-dihydroguanine
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Oxidative stress and 8-oxoguanine repair are enhanced in colon adenoma and carcinoma patients
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Imunofan - RDKVYR peptide - stimulates skin cell proliferation and promotes tissue repair
PublicationRegeneration and wound healing are vital to tissue homeostasis and organism survival. One of the biggest challenges of today's science and medicine is finding methods and factors to stimulate these processes in the human body. Effective solutions to promote regenerative responses will accelerate advances in tissue engineering, regenerative medicine, transplantology, and a number of other clinical...