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Search results for: KINAZA TYROZYNOWA FLT3
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DNA-damaging imidazoacridinone C-1311 induces autophagy followed by irreversible growth arrest and senescence in human lung cancer cells
PublicationImidazoacridinone 5-diethylaminoethylamino-8-hydroxyimidazoacridinone (C-1311) is an antitumor inhibitor of topoisomerase II and FMS-like tyrosine kinase 3 receptor. In this study, we describe the unique sequence of cellular responses to C-1311 in human non-small cell lung cancer (NSCLC) cell lines, A549 and H460. In A549 cells, C-1311 (IC80 = 0.08 µM) induced G1 and G2/M arrests, whereas H460 cells (IC80 = 0.051 µM) accumulated...
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Dobrze jest... wejść na szczyt. Spotkanie z Kingą Baranowską
EventsKinga Baranowska, himalaistka, zdobywczyni dziewięciu ośmiotysięczników, będzie gościem drugiego spotkania z cyklu "Dobrze jest...". Organizatorami są Dominikańskie Duszpasterstwo Akademickie Górka i Politechnika Otwarta
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SEM images of (La0.3Sr0.6Ce0.1)0.9Me0.1Ti0.9O3-δ (Me=Co, Fe, Ni) powder materials after reduction at 1000 deg.C in hydrogen
Open Research DataThe dataset presents SEM images of (La0.3Sr0.6Ce0.1)0.9Me0.1Ti0.9O3-δ (Me=Co, Fe, Ni) powder materials after reduction at 1000 deg.C in hydrogen. The powders were synthesized via the Pechini method. The reduction was performed in order to force the exsolution process of metallic nanoparticles.
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The XRD diffraction patterns of as-prepared (La0.3Sr0.6Ce0.1)0.9Me0.1Ti0.9O3-δ (Me= Co, Fe, Ni) materials
Open Research DataThe (La0.3Sr0.6Ce0.1)0.9Me0.1Ti0.9O3-δ (Me= Co, Fe, Ni) materials were synthesized via the Pechini method. First, the reagents in the form of nitrates were weighed and dissolved in DI water. In another beaker, a stoichiometric amount of titanium (IV) butoxide (Ti(OBu)4) was mixed together with reagent-grade ethylene glycol (EG), and citric acid (CA)...
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SEM images of (La0.3Sr0.6Ce0.1)0.9(Me1Me2Ti)O3-δ (Me1,Me2=Co, Fe, Ni) powder materials after reduction at 1000 deg.C in hydrogen
Open Research DataThe dataset presents SEM images of (La0.3Sr0.6Ce0.1)0.9(Me1Me2Ti)O3-δ (Me1,Me2=Co, Fe, Ni) powder materials after reduction at 1000 deg.C in hydrogen. The powders were synthesized via the Pechini method. The reduction was performed to force the exsolution process of bimetallic nanoparticles.
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KSZTAŁTOWANIE ZABUDOWY I SYSTEMÓW ZIELENI NA TERENACH MIEJSKICH
PublicationDynamika wzrostu miast i problemy jakości ich środowiska skłaniają do badań nad możliwościami tworzenia efektywnych użytkowo systemów zieleni zintegrowanej z zabudową. Rozwijane są rozwiązania integrujące roślinność z rozwiązaniami architektonicznymi (tzw. zielona infrastruktura). Przejawem nowego podejścia do funkcji zieleni w mieście są farmy miejskie pozwalające na produkcję roślin na potrzeby społeczności lokalnej. Podjęte zostały...
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Application of nonmetallic frustrated cations in the activation of small molecules
PublicationThe concept of nonmetallic frustrated cations has been used in small molecule activation. The in situ generated ambiphilic phosphinoborinium cation activated phenyl isocyanate, diisopropylcarbodiimide, and acetonitrile under very mild conditions without any catalyst, yielding single-, double-, or mixed-activation products. Furthermore, the mechanisms of the reactions of the phosphinoborinium cation with small molecules were elucidated...
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Mathematical Modelling and Effect Size Analysis in Support of Searching for the Proteomic Signature of Radiotherapy Toxicity
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Solubility of sulfanilamide in binary solvents containing water: Measurements and prediction using Buchowski-Ksiazczak solubility model
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Benzalkonium Salts of Amino Acids – Physicochemical Properties and Anti-Microbial Activity
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Exploring the Solubility Limits of Edaravone in Neat Solvents and Binary Mixtures: Experimental and Machine Learning Study
PublicationThis study explores the edaravone solubility space encompassing both neat and binary dissolution media. Efforts were made to reveal the inherent concentration limits of common pure and mixed solvents. For this purpose, the published solubility data of the title drug were scrupulously inspected and cured, which made the dataset consistent and coherent. However, the lack of some important types of solvents in the collection called...
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Deep Eutectic Solvents as Agents for Improving the Solubility of Edaravone: Experimental and Theoretical Considerations
PublicationIn this study, both practical and theoretical aspects of the solubility of edaravone (EDA) in Deep Eutectic Solvents (DESs) were considered. The solubility of edaravone in some media, including water, can be limited, which creates the need for new efficient and environmentally safe solvents. The solubility of EDA was measured spectrophotometrically and the complex intermolecular interactions within the systems were studied with...
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Deep Eutectic Solvents as Agents for Improving the Solubility of Edaravone: Experimental and Theoretical Considerations
PublicationIn this study, both practical and theoretical aspects of the solubility of edaravone (EDA) in Deep Eutectic Solvents (DESs) were considered. The solubility of edaravone in some media, including water, can be limited, which creates the need for new efficient and environmentally safe solvents. The solubility of EDA was measured spectrophotometrically and the complex intermolecular interactions within the systems were studied with...
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Сертифицированные эталонные материалы - неотъемлемый инструмент при контроле и обеспечения качества измерений.
PublicationСправочные материалы являются важным элементом системы управления и измерения обеспечения качества. Спрос на аналитическую информацию о составе различных материальных объектов делает его незаменимым является производство еще более широкий спектр материалов.
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Certified Reference Material - as a necessary tool for the quality control and quality assurance of measurements
PublicationReference materials are necessary to control and ensure the quality of the measurements. The demand for analytical information on the composition of different material objects makes it necessary to produce an even wider range of materials.
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Certyfikowane materiały odniesienia - niezbędne narzędzie w kontroli i zapewnieniu jakości wyników pomiarów.
PublicationMateriały odniesienia stanowią niezbędny element systemu kontroli i zapewnienia jakości wyników pomiarów. Zapotrzebowanie na informacje analityczne o składzie róznych obiektów materialnych sprawia, że niezbedna jest produkcja coraz szerszego spektrum materiałów.
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BEARING SYSTEMS OF WIND TURBINES – MAINTENANCE PROBLEMS
PublicationW praktyce eksploatacyjnej turbin wiatrowych o tradycyjnej konstrukcji (przekładniowych) obserwowana jest duża awaryjność przekładni, a zwłaszcza łożysk tocznych szybkoobrotowych wałów przekładni. W Polsce na zlecenie właściciela dużej farmy wiatrowej, firmy Energa Wytwarzanie S.A., Politechnika Gdańska we współpracy z Politechniką Poznańską i Akademią Górniczo Hutniczą podjęły badania mające na celu diagnozowanie przyczyn uszkodzeń...
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Modernized cathodic protection system for legs of the production rig – Evaluation during ten years of service
PublicationThe modernization of cathodic protection system of the Baltic Beta platform legs is described. It was that the sacrificial anodes cone-shaped groups were to be placed on the seabed at a depth of 80 m. The measurements results of cathodic protection effectiveness during its ten-years operation are presented. The effectiveness was assessed based on the potential value along the entire length of the legs from the sea surface to the...
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Corrosion hazards and inhibitor protection in the seawater injection system on the Baltic sea rig
PublicationOil extraction efficiency in LOTOS Petrobaltic Company is increased by means of injection of seawater into an oilfield aquifer, which is implemented on the Baltic Beta rig, operating on the Baltic Sea. Operational experience has shown a significant degree of corrosion aggressiveness in the injected water, which necessitates frequent repairs of the seawater injection installation. Evaluation of the corrosion phenomena is crucial...
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Optical switching technologies: problems and proposed solution
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Kinga Tokarska inż.
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Kinga Talaga
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Kinga Kuźniar
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Kinga Tomaszewska
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Kinga Nowak
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Kinga Filipiak mgr
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Dzieciątkowska Kinga inżynier architekt
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Kinga Batte inż. arch.
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Kinga Jędrysiak
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Kinga Tokarska
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Kinga Ostrowska
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Kinga Adamczyk Studentka położnictwa
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Ania Kinga inżynier
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Kinga Korniejenko
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Kinga Kraska
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Kinga Markowska Doktorant
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Kinga Gebauer licencjat
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Kinga Bilska mgr
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Kinga Woźniuk
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Kinga Sikora
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Kinga Wdowiarz
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Kinga Świokło student
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Kinga Dytrych mgr
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Kinga Dawidowska
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„…I głosu, którym mówił, przypomnieć nie mogę”. Dzieło sztuki jako implant pamięci
PublicationPodjęcie tematu pamięci odziedziczonej, pamięci zastępczej – co dzieje się z pamięcią, gdy świadków wydarzeń nie ma już wśród nas – jest obecnie szczególnie ważne dla pamięci o wydarzeniach II wojny, w szczególności w odniesieniu do pamięci o Zagładzie. Koncepcja „implantów pamięci”, rozumianych jako „wtórnie i post factum wykreowane: budowle, zapisy, obrazy czy filmy, a także treści wiedzy, które mają uzupełnić braki pamięci,...
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Screening of predicted synergistic multi-target therapies in glioblastoma identifies new treatment strategies
PublicationAbstract Background IDH-wildtype glioblastoma (GBM) is a highly malignant primary brain tumor with a median survival of 15 months after standard of care, which highlights the need for improved therapy. Personalized combination therapy has shown to be successful in many other tumor types and could be beneficial for GBM patients. Methods We performed the largest drug combination screen to date in GBM, using a high-throughput effort...
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Phosphinoborinium cation: a synthon for cationic B-P bond systems
PublicationHerein, we report access to phosphinoborinium cations via heterolytic cleavage of the boron-bromide bond in bromophosphinoborane. The product of the reaction was isolated as a dimeric dication possessing a planar P2B2 core. Activation of C-H and C-P bonds in the dication led to formation of the borinium-phosphaborene adduct. Reactivity studies revealed that title cation exhibits ambiphilic properties and intramolecular frustrated...
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Polyphenols composition, antioxidant and antimicrobial properties of Pinus sylvestris L. shoots extracts depending on different drying methods
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Organomercury Compounds in Environmental Samples: Emission Sources, Toxicity, Environmental Fate, and Determination
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Organotin Compounds: Environmental Fate and Analytics
PublicationFor more than 50 years, organotin compounds have been used in almost all sectors of industry. As a consequence, specific environmental compartments are affected by the emission of these xenobiotics. The emissions of organotin compounds into the environment from paints used in the shipbuilding industry for ship hull coating, and from the plant protection products are particularly significant.In 2001, the IMO introduced a global...