Search results for: GUSTAV OELSNER
-
Novel internally quenched substrate of the trypsin-like subunit of 20S eukaryotic proteasome
Publication -
Distance between the Basic Group of the Amino Acid Residue's Side Chain in Position P1of Trypsin Inhibitor CMTI-III and Asp189in the Substrate Pocket of Trypsin Has an Essential Influence on the Inhibitory Activity
Publication -
Peptomeric analogues of trypsin inhibitor SFTI-1 isolated from sunflower seeds
Publication -
A simple method for selection of trypsin chromogenic substrates using combinatorial chemistry approach
Publication -
Highly Specific Substrates of Proteinase 3 Containing 3-(2-Benzoxazol-5-yl)-l-alanine and Their Application for Detection of This Enzyme in Human Serum
Publication -
New potent cathepsin G phosphonate inhibitors
Publication -
Identification of X-DING-CD4, a new member of human DING protein family that is secreted by HIV-1 resistant CD4+ T cells and has anti-viral activity
Publication -
Design of selective substrates of proteinase 3 using combinatorial chemistry methods
Publication -
Surface plasmon resonance imaging biosensor for cathepsin G based on a potent inhibitor: Development and applications
Publication -
New chromogenic substrates of human neutrophil cathepsin G containing non-natural aromatic amino acid residues in position P1 selected by combinatorial chemistry methods
Publication -
The new fluorogenic substrates of neutrophil proteinase 3 optimized in prime site region
Publication -
Application of specific cell permeable cathepsin G inhibitors resulted in reduced antigen processing in primary dendritic cells
Publication -
Physical, chemical and biochemical properties of Western Siberia Sphagnum and Carex peat soils
Publication -
The Role of Electron Transfer in the Fragmentation of Phenyl and Cyclohexyl Boronic Acids
PublicationIn this study, novel measurements of negative ion formation in neutral potassium-neutral boronic acid collisions are reported in electron transfer experiments. The fragmentation pattern of phenylboronic acid is comprehensively investigated for a wide range of collision energies, i.e., from 10 to 1000 eV in the laboratory frame, allowing some of the most relevant dissociation channels to be probed. These studies were performed in...
-
Derecho Evolving from a Mesocyclone—A Study of 11 August 2017 Severe Weather Outbreak in Poland: Event Analysis and High-Resolution Simulation
PublicationThis study documents atmospheric conditions, development, and evolution of a severe weather outbreak that occurred on 11 August 2017 in Poland. The emphasis is on analyzing system morphology and highlighting the importance of a mesovortex in producing the most significant wind damages. A derecho-producing mesoscale convective system (MCS) had a remarkable intensity and was one of the most impactful convective storms in the history...
-
Practical Trial for Low-Energy Effective Jamming on Private Networks With 5G-NR and NB-IoT Radio Interfaces
PublicationFourth-generation (4G) mobile networks are successively replaced by fifth-generation (5G) ones, based on the new releases of the 3rd Generation Partnership Project (3GPP) standard. 5G generation is dedicated to civilian users and the conducted analytical work shows that it has numerous technological gaps that prevent its direct implementation in military communications systems. However, the recent armed world conflicts showed that...
-
Polityki pamięci i tożsamości wobec (nie)chcianego dziedzictwa. Od Gdańska do Gdańzigu
PublicationCelem artykułu jest próba odpowiedzi na pytanie, jak w zależności od polityki pamięci, pamięci zbiorowej i kultury historycznej kształtowano fizyczną przestrzeń miasta i jego obraz. Z przeprowadzonych dotychczas analiz wynika, że sposób, w jaki budowano narracje tożsamościowe, oparty był zasadniczo na konstrukcjach mitotwórczych, zwłaszcza na micie XVI–XVII-wiecznego „złotego wieku”. W Gdańsku, ze względu na bogatą przeszłość historyczną...
-
Tribological and thermal behavior with wear identification in contact interaction of the Ti6Al4V-sintered carbide with AlTiN coatings pair
Publication -
Fetal growth trajectory in type 1 pregestational diabetes (PGDM) — an ultrasound study
Publication -
EZH2 and SMYD3 expression in papillary thyroid cancer
Publication -
Partial characterization of indigo (Polygonum tinctorium Ait.) plant seeds and leaves
PublicationThe aim of this study was to assess the contents of indigo's bioactive compounds, its antioxidant and anticancer activities in acetone, hexane and DMSO extracts and to compare the overall bioactivity with another more used medicinal plant named prolipid. It was found that the contents of the bioactive compounds in the studied extracts from different parts of indigo plant varied (P < 0.05): the significantly highest content of polyphenols...
-
Survivin splice variants expression in thyroid malignancy
Publication -
Nicotinamide phosphorybosiltransferase overexpression in thyroid malignancies and its correlation with tumor stage and with survivin/survivin DEx3 expression
Publication -
Survivin DEx3 as a biomarker of thyroid cancers: A study at the mRNA and protein level
Publication -
Superconductivity in the Cu(Ir1−xPtx)2Se4spinel
Publication -
Implication of the disulfide bridge in trypsin inhibitor SFTI-1 in its interaction with serine proteinases
PublicationFourteen monocyclic analogues of trypsin inhibitor SFTI-1 isolated from sunflower seeds were synthesized by the solid-phase method. The purpose of this work was to establish the role of a disulfide bridge present in inhibitor's side chains of Cys3 and Cys11 in association with serine proteinases. This cyclic fragment was replaced by the disulfide bridges formed by L-pencillamine (Pen), homo-L-cysteine (Hcy), N-sulfanylethylglycine...
-
Design, Synthesis, and Enzymatic Evaluation of Novel ZnO Quantum Dot-Based Assay for Detection of Proteinase 3 Activity
PublicationHerein, the synthesis and application of functionalized quantum dot-based protease probes is described. Such probes are composed of nontoxic ZnO nanocrystals decorated by amino groups followed by linker and labeled peptide attachment. Spherical NH2-terminated ZnO quantum dots (QDs) with the average size ranging from 4 to 8 nm and strong emission centered at 530 nm were prepared using the sol−gel method. The fluorescence of ZnO...
-
Activity-based protein profiling guided identification of urine proteinase 3 activity in subclinical rejection after renal transplantation
Publication -
Development of the first internally-quenched fluorescent substrates of human cathepsin C: The application in the enzyme detection in biological samples
Publication -
Three Wavelength Substrate System of Neutrophil Serine Proteinases
Publication -
Induction of Secreted Human Immunodeficiency Virus Type 1 (HIV-1) Resistance Factors in CD4-Positive T Lymphocytes by Attenuated HIV-1 Infection
Publication -
Inhibition of Human and Yeast 20S Proteasome by Analogues of Trypsin Inhibitor SFTI-1
Publication -
The influence of substrate peptide length on human β‐tryptase specificity
Publication -
Poziomy stężeń lotnych związków chlorowcoorganicznych w wodach opadowych na terenie dużej aglomeracji miejskiej = Measurement of volatile chloroorganic compounds in urban rainwater (Gdańsk, Sopot, Gdynia)
PublicationW 105 próbkach opadów atmosferycznych (deszcz, deszcz ze śniegiem) zebranych z terenu Trójmiasta w okresie od listopada 2000 r. do maja 2001 r. oznaczano chloro - i bromopochodne metanu, etanu i etenu (7 różnych związków). Najczęściej wykrywanymi i oznaczanymi były: chloroform i czterochlorek węgla, (bardzo popularne rozpuszczalniki stosowane jako środki chłodzące i czyszczące). Najwyższe stężenia obserwowano w przypadku chloroformu,...
-
Fluorescence studies by quenching and protein unfolding on the interaction of bioactive compounds in water extracts of kiwi fruit cultivars with human serum albumin
PublicationThe main aim of this investigation was to characterize new kiwi fruit cultivars after cold storage treatment and to determine the similarities and differences between them, using spectroscopic methods. The chemometric comparison of kiwi fruit cultivars based on physicochemical indices during cold storage was carried out. All kiwi fruit cultivars showed a high level of correlation between the contents of phenolic compounds (polyphenols,...
-
Nitrogen-incorporated boron-doped diamond films for enhanced electrochemical supercapacitor performance
PublicationThe electrochemical (EC) supercapacitor, known for its rapid charging, reliability, and versatile applications, demands optimized electrode characteristics and an understanding of their electrochemical behaviour. Although boron-doped diamond (BDD) holds promise as a supercapacitor electrode, a crucial gap exists in comprehending its material behaviour under specific growth conditions. Here, nitrogen-incorporated BDD (N-BDD) films...
-
Titin and dystrophin serum concentration changes in patients affected by thyroid disorders
Publication -
Study on Microstructural Characterization, Mechanical Properties and Residual Stress of GTAW Dissimilar Joints of P91 and P22 Steels
PublicationThis article deals with the dissimilar joining of two different grade Cr-Mo steel (2.25Cr-1Mo: P22 and modified 9Cr-1Mo: P91) for power plant application. The dissimilar butt-welded joint was produced for conventional V groove design by using the gas tungsten arc welding (GTAW) process with the application of an ERNiCrMo-3 Ni-based super alloy filler. A microstructure characterization was performed to measure the inhomogeneity...
-
The LD loop as an important structural element required for transmission of the allosteric signal in the HtrA (DegP) protease from Escherichia coli
Publication -
Cathepsin G deficiency reduces periaortic calcium chloride injury-induced abdominal aortic aneurysms in mice
Publication -
Sounding rocket temperature and heat transfer data
Open Research DataThis dataset contains temperature and heat transfer data measured during REXUS 25 sounding rocket HEDGEHOG Experiment launched from Esrange Space Centre, Kiruna, Sweden. For experiment details, please see:
-
HEDGEHOG HEDGEHOG – Research on dynamic and thermal environment of a sounding rocket
ProjectsProject realized in Department of Mechanics and Mechatronics from 2019-05-14
-
Determination of amino acids in urine of patients with prostate cancer and benign prostate growth
Publication -
Effect of the Relative Position of the Face Milling Tool towards the Workpiece on Machined Surface Roughness and Milling Dynamics
Publication -
Improvement of machinability of Ti and its alloys using cooling-lubrication techniques: a review and future prospect
Publication -
Metrological analysis of surface quality aspects in minimum quantity cooling lubrication
Publication -
Changes of Nicotinamide Phosphoribosyltransferase Expressions in Thyroid Glands of Patients with Different Thyroid Pathologies
Publication -
Crystal structure and physical properties of Mg6Cu16Si7-typeM6Ni16Si7, for M = Mg, Sc, Ti, Nb, and Ta
PublicationW pracy dyskutowana jest synteza i struktura krystalograficzna, określona poprzez proszkową dyfrakcję rentgenowską, dla pięciu związków M6Ni16Si7, gdzie M = Mg, Sc, Ti, Nb, and Ta. Wszystkie te związki krystalizują w strukturze typu Mg6Cu16Si7.
-
Crystal structure and physical properties of Mg6Cu16Si7-type M6Ni16Si7, for M=Mg, Sc, Ti, Nb, and Ta
Publication -
Superconductivity in the Cu(Ir1-xPtx)2Se4 spinel
PublicationWe report the observation of superconductivity in the CuIr2Se4 spinel induced by partial substitution of Pt for Ir. The optimal doping level for superconductivity in Cu(Ir1-xPtx )2Se4 is x = 0.2, where Tc is 1.76 K. A superconducting Tc vs composition dome is established between the metallic, normal conductor CuIr2Se4 and semiconducting CuIrPtSe4. Electronic structure calculations show that the optimal Tc occurs near the electron count...