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Search results for: PROTON CONDUCTORS
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MP3vec: A Reusable Machine-Constructed Feature Representation for Protein Sequences
Publication—Machine Learning (ML) methods have been used with varying degrees of success on protein prediction tasks, with two inherent limitations. First, prediction performance often depends upon the features extracted from the proteins. Second, experimental data may be insufficient to construct reliable ML models. Here we introduce MP3vec, a transferable representation for protein sequences that is designed to be used specifically for sequence-to-sequence...
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Photo-acoustic response of active biological systems
PublicationZbadano dwie próbki organiczne gatunku Trunculariopsis trunculus,jedną wilgotną, drugą - suchą. W obu przypadkach zaobserwowanointensywne szerokie pasma absorpcyjne w zakresie widzialnym (żółtymi poniżej 330 nm). Widma foto-akustyczne zawierają wszystkie pasma uznane za związane z aktywnością biologiczną.
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Variable Size Twin-Rotor Wind Turbine
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Bounds on the cover time of parallel rotor walks
PublicationThe rotor-router mechanism was introduced as a deterministic alternative to the random walk in undirected graphs. In this model, a set of k identical walkers is deployed in parallel, starting from a chosen subset of nodes, and moving around the graph in synchronous steps. During the process, each node successively propagates walkers visiting it along its outgoing arcs in round-robin fashion, according to a fixed ordering. We consider...
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Bounds on the Cover Time of Parallel Rotor Walks
PublicationThe rotor-router mechanism was introduced as a deterministic alternative to the random walk in undirected graphs. In this model, a set of k identical walkers is deployed in parallel, starting from a chosen subset of nodes, and moving around the graph in synchronous steps. During the process, each node maintains a cyclic ordering of its outgoing arcs, and successively propagates walkers which visit it along its outgoing arcs in...
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Rotor Blade Geometry Optimisation in Kaplan Turbine
PublicationThe paper presents the description of method and results of rotor blade shape optimisation. The rotor blading constitutes a part ofturbine flow path. Optimisation consists in selection of the shape that minimises ratio of polytrophic loss. Shape of the blade isdefined by the mean camber line and thickness of the airfoil. Thickness is distributed around the camber line based on the ratio ofdistribution. Global optimisation was done...
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Dependence of Power Characteristics on Savonius Rotor Segmentation
PublicationSavonius rotors are large and heavy because they use drag force for propulsion. This leads to a larger investment in comparison to horizontal axis wind turbine (HAWT) rotors using lift forces. A simple construction of the Savonius rotor is preferred to reduce the production effort. Therefore, it is proposed here to use single-segment rotors of high elongation. Nevertheless, this rotor type must be compared with a multi-segment...
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Dissociative photo-double-ionization of the isoxazole molecules
PublicationThe five-membered heterocyclic rings are incorporated into a wide variety of structures that play a vital role in many biochemical processes. In particular, the isoxazole molecule appears in many bioactive compounds due to its unique ring structure that consists of one oxygen atom and one nitrogen atom at adjacent positions. The unique atomic composition and bond arrangement of isoxazole imply its specific electronic properties...
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The thermoluminescence characteristics and the glow curves of Thulium doped silica fiber exposed to 10MV photon and 21MeV electron radiation
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Thermoluminescent response of differently doped lithium magnesium phosphate (LiMgPO4, LMP) crystals to protons, neutrons and alpha particles
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Core/Shell Quantum Dots Encapsulated in Biocompatible Oil-Core Nanocarriers as Two-Photon Fluorescent Markers for Bioimaging
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Stability of delay induced oscillations in gene expression of Hes1 protein model
PublicationW pracy prezentowana jest matematyczna analiza modelu ekspresji genu białka Hes1. Rozważamy układ równań z dwoma opóźnieniami - w produkcji białka Hes1 oraz jego mRNA. Dowodzimy istnienia i jednoznaczności oraz nieujemności rozwiązań. Pokazujemy istnienie dokładnie jednego dodatniego stanu stacjonarnego. Wykazujemy, że stabilność stanu stacjonarnego zależy od sumy opóźnień. Podajemy warunek dostateczny na wystąpienie bifurkacji...
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The Nutritional Value and Biological Activity of Concentrated Protein Fraction of Potato Juice
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Serum Fatty Acid-Binding Protein 4 is Increased in Patients with Psoriasis
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Survivin DEx3 as a biomarker of thyroid cancers: A study at the mRNA and protein level
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Zeta potential and droplet size of n-tetradecane/ethanol (protein) emulsions
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Two-dimensional gel-based serum protein profile of growing piglets
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Effect of Functionalization of Carbon Nanotubes with Psychosine on Complement Activation and Protein Adsorption
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Myotilin, a New Topotecan Resistant Protein in Ovarian Cancer Cell Lines
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C-reactive protein as a diagnostic and prognostic factor in inflammatory bowel diseases
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Simulation of Protein Structure and Dynamics with the Coarse-Grained UNRES Force Field
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Inhibition of protein glycosylation reverses the MDR phenotype of cancer cell lines
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Blind prediction of homo‐ and hetero‐protein complexes: The CASP13‐CAPRI experiment
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Trial Proteomic Qualitative and Quantitative Analysis of the Protein Matrix of Submandibular Sialoliths
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Riboflavin binding protein—Chiral stationary phase: Investigation of retention mechanism
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Functional Protein Composition in Femoral Glands of Sand Lizards (Lacerta agilis)
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TOLLIP Protein Expression Predicts Unfavorable Outcome in Renal Cell Carcinoma
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CAVER 3.0: A Tool for the Analysis of Transport Pathways in Dynamic Protein Structures
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BALCONY: an R package for MSA and functional compartments of protein variability analysis
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Investigations of non-uniform structure of the tetacene layer by photoen-hanced current
PublicationBadano stany pułapkujące nośniki w powierzchniowych obszarach warstwy tetra-cenu. W badaniach wykorzystano metodę prądów fotowzmocnionych. Wykazano obe-cność różnych rozkładów energetycznych pułapek przy obu powierzchniach war-stw tetracenu.
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Comparative analysis of process alternatives for manufacturing piston rods of hydraulic cylinders.
PublicationZawarto wyniki analiz porównawczych alternatywnych technologii tłoczysk siłowników hydraulicznych w warunkach elastycznej automatyzacji wytwarzania. Uwzględniając zarówno tradycyjne struktury tych procesów z operacjami szlifowania i polerowania, jak i nowoczesne technologie z operacjami nagniatania, przedstawiono zintegrowane podejście do planowania sekwencji operacji procesu i harmonogramowania zadań produkcyjnych wraz z algorytmem...
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Relationship between Milk Protein Polymorphism and Selected Cows’ Reproductive Indices
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Changes in mussel Mytilus galloprovincialis protein profile as a reaction of water pollution
PublicationW pracy przedstawiono zmiany w profilu białkowym małża Mytilus galloprovincialis jako odpowiedź na zanieczyszczenia wody. Określono pojemność przeciwutleniającą z wykorzystaniem testu TEAC. Stwierdzono różnice w poziomie inhibicji w białku pochodzącym od małży zebranych z regionów zanieczyszczonych w stosunku do małży pochodzących z regionów czystych.Zawartość cynku i kadmu w białkach małży pochodzących z regionów zanieczyszczonych...
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Evolution towards simplicity in bacterial small heat shock protein system
PublicationEvolution can tinker with multi-protein machines and replace them with simpler single-protein systems performing equivalent functions in an equally efficient manner. It is unclear how, on a molecular level, such simplification can arise. With ancestral reconstruction and biochemical analysis, we have traced the evolution of bacterial small heat shock proteins (sHsp), which help to refold proteins from aggregates using either two...
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WYKORZYSTANIE TESTU MUSHRA W BADANIU KORZYŚCI UŻYTKOWANIA PROTEZ SŁUCHOWYCH
PublicationOcena jakości dopasowania aparatów słuchowych w kontekście korzyści, jakie może przy-nieść proteza jest złożonym zagadnieniem. Obiektywne parametry aparatów, które można wy-znaczyć (np. wzmocnienie czy pasmo przenoszenia) nie zawsze mają bezpośredni i decydujący wpływ w subiektywnej ocenie jakości dopasowania protezy słuchowej przez pacjenta. Pomiary efektywności aparatu słuchowego mogą dotyczyć wielu aspektów, między innymi kompensacji...
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Protein overproduction alters exosome secretion in Chinese hamster ovary cells
PublicationDespite the abundance of available cell lines, nearly 70% of all recombinant therapeutic proteins today are produced in Chi-nese hamster ovary (CHO) cells. The impact of protein overproduction on the secretion of exosomes by CHO cells has been investigated here. Increased secretion of extracellular vesicles (EVs) by protein overexpressing CHO cells was demonstrated with protein content assay, nanoparticle tracking analysis, and...
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Impact of AlphaFold on structure prediction of protein complexes: The CASP15‐CAPRI experiment
PublicationWe present the results for CAPRI Round 54, the 5th joint CASP-CAPRI protein assembly prediction challenge. The Round offered 37 targets, including 14 homodimers, 3 homo-trimers, 13 heterodimers including 3 antibody–antigen complexes, and 7 large assemblies. On average 70 CASP and CAPRI predictor groups, including more than 20 automatics servers, submitted models for each target. A total of 21 941 models submitted by these groups...
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Modified Peptide Molecules As Potential Modulators of Shelterin Protein Functions; TRF1
PublicationIn this work, we present studies on relatively new and still not well-explored potential anticancer targets which are shelterin proteins, in particular the TRF1 protein can be blocked by in silico designed "peptidomimetic" molecules. TRF1 interacts directly with the TIN2 protein, and this protein-protein interaction is crucial for the proper functioning of telomere, which could be blocked by our novel modified peptide molecules....
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Micellar aggregation of Triton X-100 surfactant in imidazolium ionic liquids
PublicationIn this work we investigated aggregation behavior of a nonionic surfactant Triton X-100 in eighteen imidazolium ionic liquids (ILs) with two to eight carbon atoms in cations alkyl chain, namely 1-ethyl-3-methylimidazolium, [EMIM], 1-butyl-3-methylimidazolium, [PrMIM], 3-methyl-1-propylimidazolium, [BMIM], 1-hexyl-3-methylimidazolium, [PMIM], 3-methyl-1-pentyl-imidazolium, [HMIM], and 1-octyl-3-methylimidazolium, [OMIM], and with...
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Water-mediated influence of a crowded environment on internal vibrations of a protein molecule
PublicationThe influence of crowding on the protein inner dynamics is examined by putting a single protein molecule close to one or two neighboring protein molecules. The presence of additional molecules influences the amplitudes of protein fluctuations. Also, a weak dynamical coupling of collective velocities of surface atoms of proteins separated by a layer of water is detected. The possible mechanisms of these phenomena are described....
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DSC and electrophoretic studies on protein denaturation of Anodonta woodiana (Lea, 1834)
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Novel primosomal protein B from thermophilic bacterium Thermoanerobacter tengcongensis
PublicationWe report the identification and characterization of theprimosomal protein B (PriB) from thermophilic bacteriumThermoanerobacter tengcongensis (TtePriB). It is the largestknown bacterial PriB protein consisting 216 amino acidresidues with a calculated molecular mass of 25 kDa. Surprisingly,it is functional as monomer containing two single-stranded DNA binding domain (OB-fold) and it is thecompletely new kind structure of SSB protein....
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Failure model of main elements of the ship engine crankshaft-piston assembly
PublicationThe paper presents a failure model of main elements of the crankshaft-piston assembly, based on failures ofcrankshaft-piston assembly and timing gear system of the Sulzer RD engines, retrieved from the equipment reliabilitydata of selected ships.
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Use of waste heat to improve the conditions of the piston engines start up
PublicationZespoły prądotwórcze z tłokowymi silnikami spalinowymi są obecnie powszechne stosowane jako awaryjne źródła energii elektrycznej albo elektrownie uzupełniające niedobory energii czy stabilizujące częstotliwość. Ich czas rozruchu powinien być krótki - poniżej 5 minut w przypadku dużych mocy. Zużycie silnika, zużycie paliwa i emisji spalin są silnie uzależnione od stanu cieplnego przed rozruchem. Przedstawiono pomiary laboratoryjne...
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RESEARCH OF HYDRAULIC PISTON PUMPS’ START-UP IN LOW AMBIENT TEMPERATURES
PublicationStarting hydraulic pumps in low ambient temperatures may cause: decreased hydraulic-mechanical efficiency, larger vibration of hydraulic installation, faster wear and more frequent damage to the elements of pumps, change of material properties of elements, increase of pressure drop. As a result of increase of resistance of cold oil flow in the suction pipe, large underpressure may be experienced, causing incomplete filling of pump...
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A coarse‐grained approach to NMR ‐data‐assisted modeling of protein structures
PublicationThe ESCASA algorithm for analytical estimation of proton positions from coarse-grained geometry developed in our recent work has been implemented in modeling protein structures with the highly coarse-grained UNRES model of polypeptide chains (two sites per residue) and nuclear magnetic resonance (NMR) data. A penalty function with the shape of intersecting gorges was applied to treat ambiguous distance restraints, which automatically...
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Mathematical analysis of a generalised p53-Mdm2 protein gene expression model
PublicationWe propose the generalisation of the p53-Mdm2 protein gene expression model introduced by Monk (2003). We investigate the stability of a unique positive steady state and formulate conditions which guarantee the occurrence of the Hopf bifurcation. We show that oscillatory behaviour can be caused not only by time lag in protein transcription process, but also can be present in the model without time delay. Moreover, we investigate...
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Influence of Gaps’ Geometry Change on Leakage Flow in Axial Piston Pumps
PublicationAxial piston pumps are the core elements of most medium and high-pressure hydraulic systems. High volumetric efficiency and high working pressures are the main advantages of this type of pumps. Therefore it is necessary to accurately calculate the leakage flow through the gaps to design efficient high-pressure pump. The main difficulty of such calculations is the fact, that the gaps change their geometry during pumping process....
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Interactions of protons with furan molecules studied by collision-induced emission spectroscopy at the incident energy range of 50–1000 eV
PublicationInvestigations of the ion-molecule reactions provide insight into many fields ranging from the stellar wind interaction with interstellar media, up to medicine and industrial applications. Besides the applications, the understanding of these processes is itself a problem of fundamental importance. Thus, interactions of protons with the gas-phase furan molecules have been investigated for the first time in the energy range of 50–1000...
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Correlation between the Reactivity and Spectroscopic Properties of N-Substituted Secondary Thioamides. New Intramolecular N• •H+• •N Binding Approach and Proton Complexes Based on Thioamide Ligation
PublicationFrom a comparison of chem. shifts and wavenumbers of several secondary thioamides and amides having monocationic substituents attached to thiocarbamoyl or carbamoyl groups by a polymethylene chain, new intramol. unconventional N···H+···N H bonding effects were discovered. It is argued that the CH2-N rotation is hindered and two +H···NHMe nonequiv. protons occur in a proton spectrum of hydrochloride RCH2C(S)NH(CH2)3NHMe-HCl...