Wyniki wyszukiwania dla: cancer

• D-loop sequences retrieved from Canis lupus familiaris mitochondrial genome

  Dane Badawcze

  open access

  • K. Kowal
  • B. Ślaska
  • A. Tkaczyk-Wlizło

  Canine mitochondrial genome is built of 16727 bp. Non-coding control region (mtCR), called also D-loop, begins with 15458 nucleotide and ends with 16727 nucleotide. The length of this fragment is 1270 bp (Kim et al., 1998). D-loop region is responsible for replication and transcription of mitochondrial DNA. Mutations that occur within it may cause irregularity...

• Phosphoroorganic Metal Complexes in Therapeutics

  Publikacja

  • S. Demkowicz
  • W. Kozak
  • M. Daśko
  • J. Rachoń

  - MINI-REVIEWS IN MEDICINAL CHEMISTRY - Rok 2016

  The present mini-review highlights recent developments on antitumor activity of metal-based therapeutics which have been a subject of researches for the last few decades. In 1965, Rosenberg found that during an electrolysis on platinum electrodes a complex of Pt is generated which inhibited to a great extent a binary fission in Escherichia coli bacteria. This discovery started a new chapter in medicinal chemistry and the interesting...

  Pełny tekst do pobrania w serwisie zewnętrznym

• Evaluating experimental molecular physics studies of radiation damage in DNA*

  Publikacja

  • M. Śmiałek-Telega

  - EUROPEAN PHYSICAL JOURNAL D - Rok 2016

  The field of Atomic and Molecular Physics (AMP) is a mature field exploring the spectroscopy, excitation, ionisation of atoms and molecules in all three phases. Understanding of the spectroscopy and collisional dynamics of AMP has been fundamental to the development and application of quantum mechanics and is applied across a broad range of disparate disciplines including atmospheric sciences, astrochemistry, combustion and environmental...

  Pełny tekst do pobrania w portalu

• Hydroperoxyl radical and formic acid formation from common DNA stabilizers upon low energy electron attachment

  Publikacja

  • A. Ribar
  • S. Huber
  • M. Śmiałek-Telega
  • K. Tanzer
  • M. Neustetter
  • R. Schürmann
  • I. Bald
  • S. Denifl

  - PHYSICAL CHEMISTRY CHEMICAL PHYSICS - Rok 2018

  2-Amino-2-(hydroxymethyl)-1,3-propanediol (TRIS) and ethylenediaminetetraacetic acid (EDTA) are key components of biological buffers and are frequently used as DNA stabilizers in irradiation studies. Such surface or liquid phase studies are done with the aim to understand the fundamental mechanisms of DNA radiation damage and to improve cancer radiotherapy. When ionizing radiation is used, abundant secondary electrons are formed...

  Pełny tekst do pobrania w serwisie zewnętrznym

• Explicit solvent repulsive scaling replica exchange molecular dynamics ( RS‐REMD ) in molecular modeling of protein‐glycosaminoglycan complexes

  Publikacja

  • M. Marcisz
  • M. Gaardløs
  • K. Bojarski
  • T. Siebenmorgen
  • M. Zachariasen
  • S. A. Samsonov

  - JOURNAL OF COMPUTATIONAL CHEMISTRY - Rok 2022

  Glycosaminoglcyans (GAGs), linear anionic periodic polysaccharides, are crucial for many biologically relevant functions in the extracellular matrix. By interacting with proteins GAGs mediate processes such as cancer development, cell proliferation and the onset of neurodegenerative diseases. Despite this eminent importance of GAGs, they still represent a limited focus for the computational community in comparison to other classes...

  Pełny tekst do pobrania w serwisie zewnętrznym

• ADT in mammography

  Publikacja

  • M. Kaczmarek
  • M. Moderhak
  • A. Z. Nowakowski

  - Rok 2013

  We discuss limitations of the known methods of IR imaging in diagnostics of breast cancer. In conclusion we show that for practical reasons one requires new approaches because the known methods based on simple observation of external temperature distribution are not fully effective. Even advanced pattern recognition could not help too much for static images. We ask the question: may active dynamic thermography, known in nondestructive...

• Isothiocyanates may chemically detoxify mutagenic amines formed in heat processed meat

  Publikacja

  • A. Lewandowska
  • W. Przychodzeń
  • B. Kusznierewicz
  • D. Kołodziejski
  • J. Namieśnik
  • A. Bartoszek-Pączkowska

  - FOOD CHEMISTRY - Rok 2014

  Meat consumption represents a dietary risk factor increasing the incidence of common cancers, probably due to carcinogenic amines (HAAs) formed upon meat heating. Interestingly, cancers whose incidence is increased by meat consumption, are decreased in populations consuming brassica vegetables regularly. This inverse correlation is attributed to brassica anticarcinogenic components, especially isothiocyanates (ITCs) that stimulate...

  Pełny tekst do pobrania w portalu

• Genetic predisposition to inflammatory bowel disease

  Publikacja

  • B. Ferra
  • M. Góra-Gębka
  • R. Kotlowski
  • L. Holec-Gąsior
  • D. Drapała

  - Acta Biochimica Polonica - Rok 2012

  Inflammatory bowel disease (IBD) is a chronic, incurable inflammatory disease of the digestive system. The two main disease entities included in the IBD are ulcerative colitis and Crohn's disease. According to epidemiological studies there are more and more new cases every year. In especially among the youngest patients with symptoms of malnutrition and growth inhibition to land up in hospitalwith cancer suspected. The purpose...

  Pełny tekst do pobrania w serwisie zewnętrznym

• Triazoloacridone C-1305 impairs XBP1 splicing by acting as a potential IRE1α endoribonuclease inhibitor

  Publikacja

  • S. Bartoszewska
  • J. Króliczewski
  • D. Crossman
  • A. Pogorzelska
  • M. Bagiński
  • J. F. Collawn
  • R. Bartoszewski

  - CELLULAR & MOLECULAR BIOLOGY LETTERS - Rok 2021

  Inositol requiring enzyme 1 alpha (IRE1α) is one of three signaling sensors in the unfolding protein response (UPR) that alleviates endoplasmic reticulum (ER) stress in cells and functions to promote cell survival. During conditions of irrevocable stress, proapoptotic gene expression is induced to promote cell death. One of the three signaling stressors, IRE1α is an serine/threonine-protein kinase/endoribonuclease (RNase) that...

  Pełny tekst do pobrania w portalu

• Invasive breast carcinoma of no special type - Female, 51 - Tissue image [7100730013393741]

  Dane Badawcze

  open access

  • Gdański Uniwersytet Medyczny

  This is the histopathological image of BREAST tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: VS200 Olympus slide scanner (20x magnification) and saved to DICOM format.

• Invasive breast carcinoma of no special type - Female, 51 - Tissue image [7100730013396771]

  Dane Badawcze

  open access

  • Gdański Uniwersytet Medyczny

  This is the histopathological image of BREAST tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: VS200 Olympus slide scanner (20x magnification) and saved to DICOM format.

• Invasive breast carcinoma of no special type - Female, 51 - Tissue image [7100730013399511]

  Dane Badawcze

  open access

  • Gdański Uniwersytet Medyczny

  This is the histopathological image of BREAST tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: VS200 Olympus slide scanner (20x magnification) and saved to DICOM format.

• Invasive breast carcinoma of no special type - Female, 51 - Tissue image [7100730013395141]

  Dane Badawcze

  open access

  • Gdański Uniwersytet Medyczny

  This is the histopathological image of BREAST tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: VS200 Olympus slide scanner (20x magnification) and saved to DICOM format.

• Invasive breast carcinoma of no special type - Female, 51 - Tissue image [7100730013397651]

  Dane Badawcze

  open access

  • Gdański Uniwersytet Medyczny

  This is the histopathological image of BREAST tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: VS200 Olympus slide scanner (20x magnification) and saved to DICOM format.

• Invasive breast carcinoma of no special type - Female, 65 - Tissue image [7100730013381381]

  Dane Badawcze

  open access

  • Gdański Uniwersytet Medyczny

  This is the histopathological image of BREAST tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: VS200 Olympus slide scanner (20x magnification) and saved to DICOM format.

• Invasive breast carcinoma of no special type - Female, 66 - Tissue image [7100730013393151]

  Dane Badawcze

  open access

  • Gdański Uniwersytet Medyczny

  This is the histopathological image of BREAST tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: VS200 Olympus slide scanner (20x magnification) and saved to DICOM format.

• Invasive breast carcinoma of no special type - Female, 66 - Tissue image [7100730013391861]

  Dane Badawcze

  open access

  • Gdański Uniwersytet Medyczny

  This is the histopathological image of BREAST tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: VS200 Olympus slide scanner (20x magnification) and saved to DICOM format.

• Invasive breast carcinoma of no special type - Female, 66 - Tissue image [7100730013395071]

  Dane Badawcze

  open access

  • Gdański Uniwersytet Medyczny

  This is the histopathological image of BREAST tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: VS200 Olympus slide scanner (20x magnification) and saved to DICOM format.

• Invasive breast carcinoma of no special type - Female, 66 - Tissue image [7100730013391271]

  Dane Badawcze

  open access

  • Gdański Uniwersytet Medyczny

  This is the histopathological image of BREAST tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: VS200 Olympus slide scanner (20x magnification) and saved to DICOM format.

• Invasive breast carcinoma of no special type - Female, 66 - Tissue image [7100730013398691]

  Dane Badawcze

  open access

  • Gdański Uniwersytet Medyczny

  This is the histopathological image of BREAST tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: VS200 Olympus slide scanner (20x magnification) and saved to DICOM format.

• Metal nanoparticles-assisted early diagnosis of diseases

  Publikacja

  • M. Jouyandeh
  • S. M. Sajadi
  • F. Seidi
  • S. Habibzadeh
  • M. T. Munir
  • O. Abida
  • S. Ahmadi
  • D. Kowalkowska-Zedler
  • N. Rabiee
  • M. Rabiee... i 4 innych

  - OpenNano - Rok 2022

  Early diagnosis is essential for the effective illness treatment, but traditional diagnostic approaches inevitably have major downsides. Recent advancements in nanoparticle-based biosensors have created new opportunities for accelerating diagnosis. High surface area, exceptional sensitivity, high specificity, and optical characteristics of metal and metal oxide nanoparticles have made it possible to detect a variety of health conditions...

  Pełny tekst do pobrania w portalu

• The Usefulness of Cyclic Diamidines with Different Core-substituents as Antitumor Agents

  Publikacja

  • J. Spychala

  - BIOORGANIC CHEMISTRY - Rok 2008

  A series of related polycationic compds. has been screened for potential antitumor activity by the NCI's in vitro testing (one dose primary anticancer assay and the NCI-60 full panel screening).  The GI50 values of triazines 3 and 4 are on av. 1.9 μM and 2.4 μM, resp.  Furan 8 deserves mention too (1.9 μM).  The biol. test results showed that carbazole 10 possessed cytotoxic activity in the nanomolar range, much better than...

  Pełny tekst do pobrania w serwisie zewnętrznym

• Poloxamer: A versatile tri-block copolymer for biomedical applications

  Publikacja

  • P. Zarrintaj
  • J. D. Ramsey
  • A. Samadi
  • Z. Atoufi
  • M. K. Yazdi
  • M. Ganjali
  • L. M. Amirabad
  • E. Zangene
  • M. Farokhi
  • K. Formela... i 3 innych

  - Acta Biomaterialia - Rok 2020

  Poloxamers, also called Pluronic, belong to a unique class of synthetic tri-block copolymers containing central hydrophobic chains of poly(propylene oxide) sandwiched between two hydrophilic chains of poly(ethylene oxide). Some chemical characteristics of poloxamers such as temperature-dependent self-assembly and thermo-reversible behavior along with biocompatibility and physiochemical properties make poloxamer-based biomaterials...

  Pełny tekst do pobrania w portalu

• Adenocarcinoma, NOS - Male, 75 - Tissue image [6210730043079541]

  Dane Badawcze

  open access

  • Gdański Uniwersytet Medyczny

  This is the histopathological image of STOMACH tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: VS200 Olympus slide scanner (20x magnification) and saved to DICOM format.

• Adenocarcinoma, NOS - Male, 75 - Tissue image [6210730043071051]

  Dane Badawcze

  open access

  • Gdański Uniwersytet Medyczny

  This is the histopathological image of STOMACH tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: VS200 Olympus slide scanner (20x magnification) and saved to DICOM format.

• Adenocarcinoma, NOS - Male, 65 - Tissue image [6210730043077781]

  Dane Badawcze

  open access

  • Gdański Uniwersytet Medyczny

  This is the histopathological image of STOMACH tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: VS200 Olympus slide scanner (20x magnification) and saved to DICOM format.

• Adenocarcinoma, NOS - Male, 75 - Tissue image [6210730043073191]

  Dane Badawcze

  open access

  • Gdański Uniwersytet Medyczny

  This is the histopathological image of STOMACH tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: VS200 Olympus slide scanner (20x magnification) and saved to DICOM format.

• Adenocarcinoma, NOS - Male, 75 - Tissue image [6210730043072281]

  Dane Badawcze

  open access

  • Gdański Uniwersytet Medyczny

  This is the histopathological image of STOMACH tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: VS200 Olympus slide scanner (20x magnification) and saved to DICOM format.

• Adenocarcinoma, NOS - Male, 75 - Tissue image [6210730043076901]

  Dane Badawcze

  open access

  • Gdański Uniwersytet Medyczny

  This is the histopathological image of STOMACH tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: VS200 Olympus slide scanner (20x magnification) and saved to DICOM format.

• Adenocarcinoma, NOS - Male, 75 - Tissue image [6210730043077911]

  Dane Badawcze

  open access

  • Gdański Uniwersytet Medyczny

  This is the histopathological image of STOMACH tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: VS200 Olympus slide scanner (20x magnification) and saved to DICOM format.

• Adenocarcinoma, NOS - Female, 70 - Tissue image [6210730043068741]

  Dane Badawcze

  open access

  • Gdański Uniwersytet Medyczny

  This is the histopathological image of STOMACH tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: VS200 Olympus slide scanner (20x magnification) and saved to DICOM format.

• BREAST, Mammary gland - Female, 46 - Tissue image [5230730013279871]

  Dane Badawcze

  open access

  • Gdański Uniwersytet Medyczny

  This is the histopathological image of BREAST tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: VS200 Olympus slide scanner (20x magnification) and saved to DICOM format.

• BREAST, Mammary gland - Female, 65 - Tissue image [5230730013286241]

  Dane Badawcze

  open access

  • Gdański Uniwersytet Medyczny

  This is the histopathological image of BREAST tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: VS200 Olympus slide scanner (20x magnification) and saved to DICOM format.

• BREAST, Mammary gland - Female, 65 - Tissue image [5230730013281441]

  Dane Badawcze

  open access

  • Gdański Uniwersytet Medyczny

  This is the histopathological image of BREAST tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: VS200 Olympus slide scanner (20x magnification) and saved to DICOM format.

• BREAST, Mammary gland - Female, 65 - Tissue image [5230730013284131]

  Dane Badawcze

  open access

  • Gdański Uniwersytet Medyczny

  This is the histopathological image of BREAST tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: VS200 Olympus slide scanner (20x magnification) and saved to DICOM format.

• BREAST, Mammary gland - Female, 46 - Tissue image [5230730013273471]

  Dane Badawcze

  open access

  • Gdański Uniwersytet Medyczny

  This is the histopathological image of BREAST tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: VS200 Olympus slide scanner (20x magnification) and saved to DICOM format.

• BREAST, Mammary gland - Female, 46 - Tissue image [5230730013273641]

  Dane Badawcze

  open access

  • Gdański Uniwersytet Medyczny

  This is the histopathological image of BREAST tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: VS200 Olympus slide scanner (20x magnification) and saved to DICOM format.

• BREAST, Mammary gland - Female, 46 - Tissue image [5230730013274161]

  Dane Badawcze

  open access

  • Gdański Uniwersytet Medyczny

  This is the histopathological image of BREAST tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: VS200 Olympus slide scanner (20x magnification) and saved to DICOM format.

• BREAST, Mammary gland - Female, 65 - Tissue image [5230730013282511]

  Dane Badawcze

  open access

  • Gdański Uniwersytet Medyczny

  This is the histopathological image of BREAST tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: VS200 Olympus slide scanner (20x magnification) and saved to DICOM format.

• BREAST, Mammary gland - Female, 65 - Tissue image [5230730013288221]

  Dane Badawcze

  open access

  • Gdański Uniwersytet Medyczny

  This is the histopathological image of BREAST tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: VS200 Olympus slide scanner (20x magnification) and saved to DICOM format.

• BREAST, Mammary gland - Female, 46 - Tissue image [5230730013274751]

  Dane Badawcze

  open access

  • Gdański Uniwersytet Medyczny

  This is the histopathological image of BREAST tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: VS200 Olympus slide scanner (20x magnification) and saved to DICOM format.

• BREAST, Mammary gland - Female, 65 - Tissue image [5230730013286141]

  Dane Badawcze

  open access

  • Gdański Uniwersytet Medyczny

  This is the histopathological image of BREAST tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: VS200 Olympus slide scanner (20x magnification) and saved to DICOM format.

• BREAST, Mammary gland - Female, 65 - Tissue image [5230730013279881]

  Dane Badawcze

  open access

  • Gdański Uniwersytet Medyczny

  This is the histopathological image of BREAST tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: VS200 Olympus slide scanner (20x magnification) and saved to DICOM format.

• BREAST, Mammary gland - Female, 46 - Tissue image [5230730013272421]

  Dane Badawcze

  open access

  • Gdański Uniwersytet Medyczny

  This is the histopathological image of BREAST tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: VS200 Olympus slide scanner (20x magnification) and saved to DICOM format.

• BREAST, Mammary gland - Female, 46 - Tissue image [5230730013273651]

  Dane Badawcze

  open access

  • Gdański Uniwersytet Medyczny

  This is the histopathological image of BREAST tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: VS200 Olympus slide scanner (20x magnification) and saved to DICOM format.

• BREAST, Mammary gland - Female, 46 - Tissue image [523073001327161]

  Dane Badawcze

  open access

  • Gdański Uniwersytet Medyczny

  This is the histopathological image of BREAST tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: VS200 Olympus slide scanner (20x magnification) and saved to DICOM format.

• BREAST, Mammary gland - Female, 65 - Tissue image [5230730013287741]

  Dane Badawcze

  open access

  • Gdański Uniwersytet Medyczny

  This is the histopathological image of BREAST tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: VS200 Olympus slide scanner (20x magnification) and saved to DICOM format.

• BREAST, Mammary gland - Female, 46 - Tissue image [5230730013276481]

  Dane Badawcze

  open access

  • Gdański Uniwersytet Medyczny

  This is the histopathological image of BREAST tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: VS200 Olympus slide scanner (20x magnification) and saved to DICOM format.

• BREAST, Mammary gland - Female, 46 - Tissue image [5230730013278771]

  Dane Badawcze

  open access

  • Gdański Uniwersytet Medyczny

  This is the histopathological image of BREAST tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: VS200 Olympus slide scanner (20x magnification) and saved to DICOM format.

• Adenocarcinoma, NOS - Male, 60 - Tissue image [621073004307631]

  Dane Badawcze

  open access

  • Gdański Uniwersytet Medyczny

  This is the histopathological image of STOMACH tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: VS200 Olympus slide scanner (20x magnification) and saved to DICOM format.