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Wyniki wyszukiwania dla: database, mirna, sirna, snorna, rna interference
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SiMiSnoRNA: Collection of siRNA, miRNA, and snoRNA database for RNA Interference
PublikacjaObjective:The discovery of sequence specific gene silencing which occurs due to the presence of double-stranded RNAs has considerable impact on biology, revealing an unknown level of regulation of gene expression. This process is known as RNA interference (RNAi) or RNA silencing in which RNA molecules inhibit gene expression, typically by causing the destruction of specific mRNA molecule. Two types of small RNA molecules - small...
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The hypoxia‐induced changes in miRNA‐mRNA in RNA ‐induced silencing complexes and HIF ‐2 induced miRNAs in human endothelial cells
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EASY ACCESS TOOL FOR SMALL INTERFERING RNA (siRNA) DATA
PublikacjaFor many decades it was an accepted dogma of molecular genetics that the expression of genes is a “one-way-road” leading only in one direction from DNA to RNA to proteins. Recent discoveries in modern molecular genetics have challenged this dogma showing that specific RNA molecules play a central role in controlling the activity of genes by changing the structure of DNA sequences, targeting other RNAs for degradation or blocking...
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mRNA adenosine methylase (MTA) deposits m 6 A on pri-miRNAs to modulate miRNA biogenesis in Arabidopsis thaliana
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The Role of miRNA in Papillary Thyroid Cancer in the Context of miRNA Let-7 Family
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Recent Insights into Plant miRNA Biogenesis: Multiple Layers of miRNA Level Regulation
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Simultaneous siRNA-mediated silencing of pairs of genes coding for enzymes involved in glycosaminoglycan synthesis.
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Posttranscriptional coordination of splicing and miRNA biogenesis in plants
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Comparison of siRNA-mediated silencing of glycosaminoglycan synthesis genes and enzyme replacement therapy for mucopolysaccharidosis in cell culture studies.
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The Role of miRNA-7 in the Biology of Cancer and Modulation of Drug Resistance
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Diagnostic potential for a serum miRNA neural network for detection of ovarian cancer
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Potential of Liquid Biopsy in Papillary Thyroid Carcinoma in Context of miRNA, BRAF and p53 Mutation
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Is the Identification of SNP-miRNA Interactions Supporting the Prediction of Human Lymphocyte Transcriptional Radiation Responses?
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Salt Stress Reveals a New Role for ARGONAUTE1 in miRNA Biogenesis at the Transcriptional and Posttranscriptional Levels
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SERRATE interacts with the nuclear exosome targeting (NEXT) complex to degrade primary miRNA precursors in Arabidopsis
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Analysis of Let-7 Family miRNA in Plasma as Potential Predictive Biomarkers of Diagnosis for Papillary Thyroid Cancer
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Serum miRNA-based signature indicates radiation exposure and dose in humans: a multicenter diagnostic biomarker study
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Serum miRNA-based signature indicates radiation exposure and dose in humans: A multicenter diagnostic biomarker study
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Circulating miRNA profiles and the risk of hemorrhagic transformation after thrombolytic treatment of acute ischemic stroke: a pilot study
PublikacjaBackground: Hemorrhagic transformation (HT) in acute ischemic stroke is likely to occur in patients treated with intravenous thrombolysis (IVT) and may lead to neurological deterioration and symptomatic intracranial hemorrhage (sICH). Despite the complex inclusion and exclusion criteria for IVT and some useful tools to stratify HT risk, sICH still occurs in approximately 6% of patients because some of the risk factors for this...
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EPAS1 resistance to miRNA-based regulation contributes to prolonged expression of HIF-2 during hypoxia in human endothelial cells
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Reduction of human chorionic gonadotropin beta subunit expression by modified U1 snRNA caused apoptosis in cervical cancer cells
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Novel Nuclear Functions of Arabidopsis ARGONAUTE1: Beyond RNA Interference
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A microcomputer database design
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Photoelectron-photoabsorption (PePa) database
PublikacjaIn this paper a recently launched Photoelectron-Photoabsorption Database is presented. The database was developed in order to gather all the photoelectron and photoabsorption spectra measured by various collaborators over the years as well as to ease the access to the data to the potential users. In the paper the main features of the database were described and its outline explained.
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Role of miR-15b/16–2 cluster network in endometrial cancer: An in silico pathway and prognostic analysis
PublikacjaEndometrial cancer (EC) is the second most common cancer in women. A large number of human cancers exhibit dysregulation of microRNA expression including EC. MiR-15b/16–2 is one of the best-known miRNA clusters that is expressed in many types of cancer tissues. Herein, we analyzed the expression of individual miR-15b/16–2 cluster members, its paralogues, and their target network analysis, as well as their prognostic significance...
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Analysis of aircraft magnetic interference
PublikacjaThe magnetometric method is used among other things on mobile platforms (planes, helicopters) in military systems and in geological research. Optically-pumped and SQUID magnetometers are used in magnetic systems on airplanes. To be able to attain the sensitivity of modern magnetometers in flight, it is important that maneuver-related magnetic interference effects be minimized. The mathematical model of an aircraft as a source of...
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Analysis of aircraft magnetic interference
PublikacjaThe magnetometric method is used among other things on mobile platforms (planes, helicopters) in military systems and in geological research. Optically-pumped and SQUID magnetometers are used in magnetic systems on airplanes. To be able to attain the sensitivity of modern magnetometers in flight, it is important that maneuver-related magnetic interference effects be minimized. The mathematical model of an aircraft as a source of...
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A Database Schema for the Analysis of Global Dynamics
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Querying the digital database of musical documents
PublikacjaW rozdziale zaprezentowano program Melody Explorer służący do formułowania zapytań dla bazy danych dokumentów muzycznych. Przedstawiono problemy związane z konwersją informacji wprowadzanych przez użytkownika na zapis nutowy. Zaproponowano ulepszenia istniejących rozwiązań mające na celu poprawę dokładności i stabilności systemu. Oprócz cyfrowego zapisu dźwięku również podany przez użytkownika rytm melodii wykorzystywany jest do...
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Broadband interference in speech reinforcement systems
PublikacjaArtykuł podejmuje niedoceniany problem wpływu liczby i rozkładu głośników w systemach nagłośnienia, na jakość przekazu głosowego, czyli na zrozumiałość mowy w audytoriach. Superpozycji przesuniętych w czasie szerokopasmowych sygnałów o tym samym kształcie i lekko różnych wielkościach, które docierają do słuchacza z licznych spójnych źródeł, towarzyszy zjawisko interferencji prowadzące do głębokiej modyfikacji odbieranych sygnałów...
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mRNA profiling for vaginal fluid and menstrual blood identification
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Internet database for photogrametric close range applications
PublikacjaPublikacja przedstawia koncepcję systemu informacyjnego przeznaczonego do gromadzenia, prezentowania i publikowania przez Internet numerycznych i cyfrowych wyników pomiarów fotogrametrycznych z różnych aplikacji fotogrametrycznych umożliwiających opracowania bliskiego zasięgu.
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FEEDB: A multimodal database of facial expressions and emotions
PublikacjaIn this paper a first version of a multimodal FEEDB database of facial expressions and emotions is presented. The database contains labeled RGB-D recordings of people expressing a specific set of expressions that have been recorded using Microsoft Kinect sensor. Such a database can be used for classifier training and testing in face recognition as well as in recognition of facial expressions and human emotions. Also initial experiences...
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Cooperative editing approach for building Wordnet database
PublikacjaArtykuł przedstawia podejście do kooperacyjnej pracy nad baza danych systemu Wordnet. Opisana została architektura systemu oraz wizualizacja sieci powiązań konceptualnych z użyciem komponentu touchgraph.
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On Facial Expressions and Emotions RGB-D Database
PublikacjaThe goal of this paper is to present the idea of creating reference database of RGB-D video recordings for recognition of facial expressions and emotions. Two different formats of the recordings used for creation of two versions of the database are described and compared using different criteria. Examples of first applications using databases are also presented to evaluate their usefulness.
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La sfida di "Re Cotone". Una nuova storia del capitalismo attraverso la storia delle commodities?
PublikacjaThe article is divided into two parts. In the first one, it highlights the role of commodities in real economy and it observes the coincidence of their price increase after 2003 and their importance as a research topic particularly in the framework of global history. In the second one, it propose a comparative analysis of two recent books on cotton, considering similarities and differences of their approaches, and the difficult...
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mRNA heptaplex protocol for distinguishing between menstrual and peripheral blood
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Nonsense-Mediated mRNA Decay: Pathologies and the Potential for Novel Therapeutics
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Multifrequency self-optimizing narrowband interference canceller
PublikacjaThe problem of cancellation of a nonstationary sinusoidal interference, acting at the output of a linear stable plant, is considered. It is assumed that disturbance is a multifrequency narrowband signal, and that system output is contaminated with wideband noise. It is not assumed that the reference signal is available. Two disturbance cancelling schemes are proposed, one for disturbances with unrelated frequency components, and...
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Multichannel self-optimizing narrowband interference canceller
PublikacjaThe problem of cancellation of a nonstationary sinusoidal interference, acting at the output of an unknown multivariable linear stable plant, is considered. No reference signal is assumed to be available. The proposed feedback controller is a nontrivial extension of the SONIC (self-optimizing narrowband interference canceller) algorithm, developed earlier for single-input, single-output plants. The algorithm consists of two loops:...
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Direct laser interference patterning: theory and application
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Simulation of compensator of magnetic interference caused by an aircraft .
PublikacjaW badaniach geologicznych Ziemi wykorzystuje się m.in. metodę magnetometryczną. Metoda ta polega na pomiarze indukcji magnetycznej na badanym obszarze. Na podstawie rozkładu pola magnetycznego można zlokalizować różnego rodzaje złoża mineralne. Poszukiwania geologiczne wykonywane są na dużych obszarach z wykorzystaniem samolotu. Samolot w swoim otoczeniu zniekształca pole magnetyczne, dlatego też system pomiarowy musi zawierać...
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Improving the quality of speech in the conditions of noise and interference
PublikacjaThe aim of the work is to present a method of intelligent modification of the speech signal with speech features expressed in noise, based on the Lombard effect. The recordings utilized sets of words and sentences as well as disturbing signals, i.e., pink noise and the so-called babble speech. Noise signal, calibrated to various levels at the speaker's ears, was played over two loudspeakers located 2 m away from the speaker. In...
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Syntactic modular decomposition of large ontologies with relational database
PublikacjaSupport for modularity allows complex ontologies to be separated into smaller pieces (modules) that are easier to maintain and compute. Instead of considering the entire complex ontology, users may benefit more by starting from a problem-specific set of concepts (signature of problem) from the ontology and exploring its surrounding logical modules. Additionally, an ontology modularization mechanism allows for the splitting up of...
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Remote Spatial Database Access in the Navigation System for the Blind
PublikacjaThe article presents the problem of a database access in the navigation systems. The authors were among the main creators of the prototype navigation system for the blind - “Voice Maps”. In the implemented prototype only exemplary, limited spatial data were used, therefore they could be stored in the mobile device’s memory without any difficulties. Currently the aforementioned system is being prepared for commercialization - the...
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An extension to the FEEDB Multimodal Database of Facial Expressions and Emotions
PublikacjaFEEDB is a multimodal database that contains recordings of people expressing different emotions, captured by using a Microsoft Kinect sensor. Data were originally provided in the device’s proprietary format (XED), requiring both the Microsoft Kinect Studio application and a Kinect sensor attached to the system to use the files. In this paper, we present an extension of the database. For a selection of recordings, we also provide...
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A Database Schema for the Analysis of Global Dynamics of Multiparameter Systems
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Is database a necessary tool in research? Some historical facts
PublikacjaAutorzy rozważają argumenty za i przeciw używaniu baz danych w badaniach naukowych, a w szczególności w inżynierii. Wnioski z rozważań są jednoznaczne - bazy danych są dziś koniecznością, autorzy podają przykłady zastosowań i pomysły na nowe wdrożenia systemów bazodanowych
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Evaluation Methodology for Ship’s Planned Maintenance System Database
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Database systems for tomorrow: new challenges and research areas
PublikacjaZaprezentowano nowe obszary badawcze w dziedzinie baz danych, które będą rozwijane w najbliższej przyszłości. Omówiono takie obszary jak systemy typu ''Plug and Play'', duże systemy sfederowane, nowe architektury systemów baz danych oparte na dużych buforach pamięciowych, integracja danych i aplikacji oraz bazy danych semistrukturalnych.