Wyszukiwarka
Wyniki wyszukiwania dla: Cardiotoxicity of radiotherapy
-
The clinician’s guide to radiotherapy complications
Publikacja -
MicroRNA composition of plasma extracellular vesicles: a harbinger of late cardiotoxicity of doxorubicin
Publikacja -
Volumetric staging in radiotherapy for oropharyngeal cancers
Publikacja -
Gold nanoparticles for cancer radiotherapy: a review
PublikacjaRadiotherapy is currently used in around 50% of cancer treatments and relies on the deposition of energy directly into tumour tissue. Although it is generally effective, some of the deposited energy can adversely affect healthy tissue outside the tumour volume, especially in the case of photon radiation (gamma and X-rays). Improved radiotherapy outcomes can be achieved by employing ion beams due to the characteristic energy deposition...
-
Systemic Effects of Radiotherapy and Concurrent Chemo-Radiotherapy in Head and Neck Cancer Patients—Comparison of Serum Metabolome Profiles
Publikacja -
Journal of Radiotherapy in Practice
Czasopisma -
Cancer Radiotherapie
Czasopisma -
Natural Products Counteracting Cardiotoxicity during Cancer Chemotherapy: The Special Case of Doxorubicin, a Comprehensive Review
PublikacjaCardiotoxicity is a frequent undesirable phenomenon observed during oncological treatment that limits the therapeutic dose of antitumor drugs and thus may decrease the effec-‐‑ tiveness of cancer eradication. Almost all antitumor drugs exhibit toxic properties towards cardiac muscle. One of the underlying causes of cardiotoxicity is stimulation of oxidative...
-
Statistical Integration of p-values for Enhancing Discovery of Radiotoxicity Gene Signatures
Publikacja -
RADIOTHERAPY AND ONCOLOGY
Czasopisma -
Use of a 3D printer to create a bolus for patients undergoing tele-radiotherapy
Publikacja -
Prognostic factors in postoperative radiotherapy for prostate cancer – tertiary center experience
Publikacja -
MicroRNA composition of plasma extracellular vesicles: a harbinger of late cardiotoxicity in long-term survivors of acute lymphoblastic leukemia treated with doxorubicin
Publikacja -
Accurate, robust and harmonized implementation of morpho-functional imaging in treatment planning for personalized radiotherapy
Publikacja -
Mathematical Modelling and Effect Size Analysis in Support of Searching for the Proteomic Signature of Radiotherapy Toxicity
Publikacja -
High Signal Resolution Pulse Oximetry as a Prognostic Indicator of Radiotherapy Toxicity: A Pilot Study
PublikacjaIntroduction: Radiotherapy plays a prominent role in the multidisciplinary treatment of cancers. Despite new irradiation techniques, radiation-induced cardiotoxicity remains a leading cause of morbidity and mortality. Therefore, prognostic indicators of radiotherapy toxicity are essential. This study aimed to investigate the influence of applied radiotherapy on the pulse wave recording and thereby on...
-
EP-1817: Radiotherapy-related changes in serum proteome patterns of head and neck cancer patients
Publikacja -
The Prognostic Value of PI-RADS Score in CyberKnife Ultra-Hypofractionated Radiotherapy for Localized Prostate Cancer
Publikacja -
Influence of genetic background and oxidative stress response on risk of mandibular osteoradionecrosis after radiotherapy of head and neck cancer
Publikacja -
SU‐GG‐T‐270: Evaluation of a Novel 3‐D Polymer Gel Dosimetry System for Proton Radiotherapy
Publikacja -
Reports of Practical Oncology and Radiotherapy
Czasopisma -
Transplantable Melanomas in Hamsters and Gerbils as Models for Human Melanoma. Sensitization in Melanoma Radiotherapy—From Animal Models to Clinical Trials
Publikacja -
Performance of a new commercial high-definition 3D patient specific quality assurance system for CyberKnife robotic radiotherapy and radiosurgery
PublikacjaConventional two dimensional and low-definition measurement techniques for dosimetric verification of radiotherapy treatment deliveries are no longer adequate in the era of hypofractionation and extremely high dose gradients. New quality assurance (QA) tools with 3D capability and high definition are urgently needed. The purpose of this study was to evaluate the performance of one of the first such commercial systems as applied...
-
Relationships between acute reactions to radiotherapy in head and neck cancer patients and parameters of radiation-induced DNA damage and repair in their lymphocytes
Publikacja -
Radiation-related Changes in Serum Proteome Profiles Detected by Mass Spectrometry in Blood of Patients Treated with Radiotherapy Due to Larynx Cancer
Publikacja -
Radiation-related Changes in Serum Proteome Profiles Detected by Mass Spectrometry in Blood of Patients Treated with Radiotherapy Due to Larynx Cancer
Publikacja -
Small field radiotherapy of head and neck cancer patients is responsible for oxidatively damaged DNA/oxidative stress on the level of a whole organism
Publikacja -
Systemic modulation of stress and immune parameters in patients treated for prostate adenocarcinoma by intensity-modulated radiation therapy or stereotactic ablative body radiotherapy
Publikacja -
Analysis of Circulating Tumor Cells in Patients with Non-Metastatic High-Risk Prostate Cancer before and after Radiotherapy Using Three Different Enumeration Assays
Publikacja -
Radiotherapy-related changes in serum proteome patterns of head and neck cancer patients; the effect of low and medium doses of radiation delivered to large volumes of normal tissue
Publikacja -
Brachytherapy boost improves survival and decreases risk of developing distant metastases compared to external beam radiotherapy alone in intermediate and high risk group prostate cancer patients
Publikacja -
Association between plasma proteome profiles analysed by mass spectrometry, a lymphocyte-based DNA-break repair assay and radiotherapy-induced acute mucosal reaction in head and neck cancer patients
Publikacja -
Investigation of energy deposition and its optical imaging in polymer gel dosimeters
PublikacjaThis following chapter describes methods for verifying the absorbed dose during radiotherapy. Special attention is paid to the method using polymer-gel dosimeters, the dose reading of which is performed by means of Laser Computed Tomography. The chapter also includes considerations on alternative solutions for dosimetric measurements and various types of radiotherapy and their pros and cons. In addition, both the methods of structural...
-
OC-0265: Whole body response to radiation in head and neck and prostate cancer patient; the serum proteome comparative analysis
Publikacja -
A link between seasonality and radiation-related toxicity: The big time or time will tell?
Publikacja -
Serum miRNA-based signature indicates radiation exposure and dose in humans: A multicenter diagnostic biomarker study
Publikacja -
Roadmap on dynamics of molecules and clusters in the gas phase
PublikacjaThis roadmap article highlights recent advances, challenges and future prospects in studies of the dynamics of molecules and clusters in the gas phase. It comprises nineteen contributions by scientists with leading expertise in complementary experimental and theoretical techniques to probe the dynamics on timescales spanning twenty orders of magnitudes, from attoseconds to minutes and beyond, and for systems ranging in complexity...
-
VUV photofragmentation of the six-membered heterocyclic molecules containing oxygen
PublikacjaCancer is a significant public health concern worldwide, which results in millions of deaths each year. The standard cure routine for cancer is surgery, and nowadays, radiotherapy or a hadrontherapy. Depending on the type of cancer, patients may undergo additional treatment, including targeted therapy. A combination of radio- or hadron-therapy with proper drug treatment can inhibit the proliferation of cancer cells and thus can...
-
292. Cisplatin and 5-fluorouracil in recurrent, persistent or metastatic cervical carcinoma
Publikacja -
260. The role of patients and doctors in making decisions about the choice of the kind of adjuvant treatment in early brest cancer
Publikacja -
Hydroperoxyl radical and formic acid formation from common DNA stabilizers upon low energy electron attachment
Publikacja2-Amino-2-(hydroxymethyl)-1,3-propanediol (TRIS) and ethylenediaminetetraacetic acid (EDTA) are key components of biological buffers and are frequently used as DNA stabilizers in irradiation studies. Such surface or liquid phase studies are done with the aim to understand the fundamental mechanisms of DNA radiation damage and to improve cancer radiotherapy. When ionizing radiation is used, abundant secondary electrons are formed...
-
Medical Image Segmentation Using Deep Semantic-based Methods: A Review of Techniques, Applications and Emerging Trends
PublikacjaSemantic-based segmentation (Semseg) methods play an essential part in medical imaging analysis to improve the diagnostic process. In Semseg technique, every pixel of an image is classified into an instance, where each class is corresponded by an instance. In particular, the semantic segmentation can be used by many medical experts in the domain of radiology, ophthalmologists, dermatologist, and image-guided radiotherapy. The authors...
-
The imidazoacridinone C-1311 induces p53-dependent senescence or p53-independent apoptosis and sensitizes cancer cells to radiation
PublikacjaC-1311 is a small molecule, which has shown promise in a number of preclinical and clinical studies. However, the biological response to C-1311 exposure is complicated and has been reported to involve a number of cell fates. Here, we investigated the molecular signaling which determines the response to C-1311 in both cancer and non-cancer cell lines. For the first time we demonstrate that the tumor suppressor, p53 plays a key role...
-
Thanos Of Titan
Osoby -
Follicular lymphoma, grade 1 - Female, 59 - Tissue image [910073000327131]
Dane BadawczeThis is the histopathological image of LYMPH NODES tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.
-
Lobular carcinoma, metastatic - Female, 62 - Tissue image [1230630016189961]
Dane BadawczeThis is the histopathological image of OVARY tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.
-
Follicular lymphoma, grade 1 - Female, 59 - Tissue image [9100730003272521]
Dane BadawczeThis is the histopathological image of LYMPH NODES tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.
-
Follicular lymphoma, grade 1 - Female, 59 - Tissue image [9100730003272741]
Dane BadawczeThis is the histopathological image of LYMPH NODES tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.
-
Dominant Pathways of Adenosyl Radical-Induced DNA Damage Revealed by QM/MM Metadynamics
PublikacjaBrominated nucleobases sensitize double stranded DNA to hydrated electrons, one of the dominant genotoxic species produced in hypoxic cancer cells during radiotherapy. Such radiosensitizers can therefore be administered locally to enhance treatment efficiency within the solid tumor while protecting the neighboring tissue. When a solvated electron attaches to 8-bromoadenosine, a potential sensitizer, the dissociation of bromide...
-
Lobular carcinoma, metastatic - Female, 62 - Tissue image [1230630016184251]
Dane BadawczeThis is the histopathological image of OVARY tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.