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Search results for: DNA TOPOIZOMERAZA II
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Effect of new bisacridines IKE16, IKE18 and IE10 on the yeast topoisomerase II relaxation activity
Open Research DataThe datasets contain the results of new bisacridines IKE16, IKE18 and IE10 inhibition activity against yeast topoisomerase II. DNA topoisomerases (Topo) are enzymes that catalyze changes in the spatial structure of DNA and play an important role in replication, transcription and recombination. Beyond their normal functions, DNA topo are significant...
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Phylogenetic trees of genus Oncidium Sw. based on analysis of DNA sequences
Open Research DataGenus Oncidium Sw. is widely regarded as a polyphiletic, and the taxonomic boundaries between him and such genera as Odontoglossum Kunth. or Miltonia Lindley remain blurred. The goal of the study was to determine the phylogenetic relationships within the genus Oncidium s.lato based on the DNA sequences analysis. The correlation between molecular data...
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Analysis of induction of DNA DSBs on telomeres in A549 cells
Open Research DataData consist of an analysis of DNA DSBs on telomeres. A549 were treated with compounds (TXT4, MTX, DMSO) at IC90 concentration for the indicated time. Images were acquired with an LSM 800 inverted laser scanning confocal microscope (Carl Zeiss; Dresden, Germany) equipped with an Airyscan detector using a ×63 1.4 NA Plan Apochromat objective (Carl Zeiss)....
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Flow cytometry analysis of DNA DSBs in telomerase positive and negative cell lines after treatment with TXT2 and TXT4
Open Research DataFlow cytometry analysis of DNA DSBs in telomerase positive (A549, H460) and negative (NHBE2594, U2OS) cell lines after treatment with equitoxic concentrations of TXT2 and TXT4. MTX and DMSO were used as positive and negative controls, respectively.
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Molecular differences in mitochondrial DNA (mtDNA) genomes of dogs with malignant mammary tumours
Open Research DataThe aim of this study was to determine molecular defects in mitochondrial DNA with the use of large-scale genome analysis in malignant canine mammary gland tumours and indicate whether these changes were linked with the carcinogenesis process. With the use of the NGS technology, we sequenced 27 samples of mtDNA isolated from blood and tumours obtained...
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Study of the ability of TXT-compounds to promote telomeric G4 DNA thermal stabilization using FRET melting assay
Open Research DataThe data set contains a DNA melting screen obtained from the FRET melting assay. Thermal stabilities of G-quadruplex structures were analysed in the presence and in absence of ligands. TMPyP4 and MTX were used as references. Measurements were carried out in triplicate using a LightCycler 480 thermocycler (Roche Life Science) with a filter setting of...
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IKE1-IKE3 (C-1305 derivatives) inhibitory effect of the Yeast Topoisomerase II relaxation activity
Open Research DataInhibition of Yeast Topoisomerase II were analyzed according to relaxation assay kit from Inspiralis. Briefly, 250 ng of supercoiled pBR322 DNA, 1 mM ATP, 1-200 μM of analyzed compound were mixed with reaction buffer (1 mM Tris-HCl (pH 7.9), 10 mM KCl, 0.5 mM MgCl 2, 0.2 % (v/v) glycerol). The reaction was initiated by the addition of an enzyme, allowed...
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Electrochemical measurements of borophene functionalized with nickel(II) oxide (NiO)
Open Research DataThis dataset contains linear sweep voltammetry (LSV) and chronopotentiometry (CP) technique results for borophene functionalized with nickel(II) oxide (NiO) and reference samples: ruthenium(IV) oxide (RuO2), nickel(II) oxide (NiO) and pristine borophene. Linear sweep voltammetry (LSV) results show the oxygen evolution reaction permormance of the obtained...
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X-ray diffraction (XRD) patterns of nickel(II) oxide (NiO) functionalized borophene and bulk boron
Open Research DataThese data include X-ray diffration (XRD) patterns of nickel(II) oxide (NiO) functionalized borophene before and after oxygen evolution reaction (OER), bulk boron (B), graphiic foil (GF) and nickel(II) oxide nanoparticles (NiO).
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X-ray photoelectron spectroscopy (XPS) results for nickel(II) oxide (NiO) functionalized borophene and boron
Open Research DataThis dataset contain X-ray photoelectron spectroscopy (XPS) results for nickel(II) oxide (NiO) functionalized borophene before and after oxygen evolution reacion (OER) nad bulk boron.
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Starogard Gdański 2019, Pomorska – Aleja Jana Pawła II street - video data - pedestrian, bicycles, vehicles
Open Research DataThe data contain video traffic data (pedestrian, cyclists, vehicles) registered at aleja Jana Pawła II street. Date 13.06.2019, 6:00-18:00. The video camera was installed around intersections at Pomorska and Aleja Jana Pawła II street. Camera was mounted on 7-meter-high mast.
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Video traffic data - Interchange Balice II (A4-744), Poland
Open Research DataThe data includes video traffic data registered with 12 video cameras at entry and exit lanes of the Balice II interchange within A4 motorway in Poland (interchange of motorway A4 and regional road 744), located in the Krakow Agglomeration. The data covers the two days: 29.08.2017 and 30.08.2017 (motorway A4).
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Carbon (II) oxide (CO) calibration set of FTIR spectra
Open Research DataThe calibration spectra for CO concentration calibration were supplied with this dataset
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Starogard Gdański 2019, Tadeusza Kościuszki – aleja Jana Pawła II street - video data - pedestrian, bicycles, vehicles
Open Research DataThe data contain video traffic data (pedestrian, cyclists, vehicles) registered at Kościuszki street. Date 13.06.2019, 6:00-18:00. The video camera was installed around intersections at Kościuszki and Jana Pawła II street. Camera was mounted on 7-meter-high mast.
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Confocal microscopy analysis of DNA DSB in telomerase negative cells after exposure to TXT2 and TXT4
Open Research DataThe data sets contain confocal microscopic images showing the γ-H2AX with TRF2 after treatment of NHBE and U2OS cell lines with TXT2 and TXT4 in equitoxic concentrations. Images were acquired with an LSM 800 inverted laser scanning confocal microscope (Carl Zeiss; Dresden, Germany) equipped with an Airyscan detector using a ×63 1.4 NA Plan Apochromat...
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ArchBGal32cB 441Glu mutein gene analysis dataset
Open Research Data -
Dataset of phase portraits of the fractional prey-predator model with Holling type-II interaction (without predator harvesting)
Open Research DataThe need for a fractional generalization of a given classical model is often due to new behaviors which cannot be taken into account by the model. In this situation, it can be useful to look for a fractional deformation of the initial system, trying to fit the fractional exponent of differentiation in order to catch properly the data.
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Split-beam echosounder data from Puck Bay autumn 2018 Part II
Open Research DataThe acoustic data was collected in 2018, in the Bay of Puck, in the seasons: autumn. Data was collected during the day and night. Three split-beam echosounders with frequencies of 38 kHz, 120 kHz and 333 kHz were used to collect the data. The data was collected at a designated study area not far from the city of Hel and on the route Hel - Gdynia while...
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Case Study NEB Atlas / part II - Autodesk Forma analysis / BedZED, London
Open Research DataThe data presents the results of work on the analysis of contemporary neighbourhoods. The aim of this part of the research was to analysis housing estates already existed in various cities in Europe. The analyses ware done in real time with AI and powered for key factors such as sun hours, daylight potential, noise, wind, and microclimate. These data...
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Split-beam echosounder data from Puck Bay spring 2019 Part II
Open Research DataThe acoustic data was collected in 2019, in the Bay of Puck, in the season: spring. Data was collected during the sunrise and sunset. Three split-beam echosounders with frequencies of 38 kHz, 120 kHz and 333 kHz were used to collect the data. The data was collected at a designated study area not far from the city of Hel, while the ship was sailing....