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Search results for: THERAPY
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Epigenetic-Based Therapy—A Prospective Chance for Medulloblastoma Patients’ Recovery
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Newborn screening and gene therapy in SMA: Challenges related to vaccinations
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The p53-mediated cytotoxicity of photodynamic therapy of cancer: Recent advances
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Documentation of endpoint prevention with combination therapy in hypertension is urgently needed
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Updated ESH position paper on interventional therapy of resistant hypertension
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Dosimetric evaluation of a novel polymer gel dosimeter for proton therapy
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VEGF – targeted therapy for the treatment of cervical cancer – literature review
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Diagnostic pure transgastric NOTES in an intensive therapy unit patient
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TRF1 and TRF2: pioneering targets in telomere-based cancer therapy
PublicationThis article presents an in-depth exploration of the roles of Telomere Repeat-binding Factors 1 and 2 (TRF1 and TRF2), and the shelterin complex, in the context of cancer biology. It emphasizes their emerging significance as potential biomarkers and targets for therapeutic intervention. Central to the shelterin complex, TRF1 and TRF2 are crucial in maintaining telomere integrity and genomic stability, their dysregulation often...
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Investigation of photothermolysis therapy of human skin diseases using optical phantoms
PublicationDermatological diseases, such as neurofibroma (Recklinghausen disease) or hemangiomas can be efficiently treated using photothermolysis from laser irradiation. We have utilized a developed 975 nm fiber diode laser as a low-cost alternative over common Nd:YAG lasers. This paper describes the investigations of interaction of 975 nm diode laser radiation-pulses with optical skin phantoms which were designed and manufactured in our...
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Tinnitus Therapy Based on High-Frequency Linearization Principles - Preliminary Results
PublicationThe aim of this work is to present problems related to tinnitus symptoms, its pathogenesis, hypotheses on tinnitus causes, and therapy treatment to reduce or mask the phantom noise. In addition, the hypothesis on the existence of parasitic quantization that accompanies hearing loss has been recalled. Moreover, the paper describes a study carried out by the Authors with the application of high-frequency dither having specially formed...
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Smart Pen - new multimodal computer control tool for graphomotorical therapy
PublicationW sytuacji, gdy około 15% populacji uczniów wykazuje cechy dyslektyczne, koniecznością staje się wyposażenie szkół w efektywne narzędzia do diagnozy i terapii tego rodzaju zaburzeń. Dzięki wykorzystaniu tabletu i specjalnie skonstruowanego długopisu wyposażonego w czujniki nacisku uzyskano możliwość monitorowania wielu parametrów, które do tej pory były dla terapeutów całkowicie niedostępne (np. pomiar nacisku na podłoże czy ścisku...
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H2AX phosphorylation, its role in DNA damage response and cancer therapy
PublicationDouble-strand breaks (DSBs) are the most deleterious DNA lesions, which, if left unrepaired, may have severe consequences for cell survival, as they lead to chromosome aberrations, genomic instability, or cell death. Various physical, chemical, and biological factors are involved in DSB induction. Cells respond to DNA damage by activating the so-called DNA damage response (DDR), a complex molecular mechanism developed to detect...
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Cortisol Levels in Infants with Central Coordination Disorders during Vojta Therapy
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Cortisol Levels in Infants with Central Coordination Disorders during Vojta Therapy
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Monitoring the Efficiency of Equilibrium Reactions During Therapy in Children With Postural Disorders
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Monitoring the Efficiency of Equilibrium Reactions During Therapy in Children With Postural Disorders
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Effect of renal replacement therapy on selected arachidonic acid derivatives concentration
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Effect of brefeldin A and castanospermine on resistant cell lines as supplements in anticancer therapy
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Dual-task exercise as a therapy for executive motor function in Parkinson’s disease
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Nurses and Pharmacists in Interdisciplinary Team of Health Care Providers in Photodynamic Therapy
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Antithrombotic therapy in patients with atrial fibrillation undergoing percutaneous coronary intervention
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Theophylline Therapy for Near-Fatal Cheyne–Stokes Respiration: A Case Report
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Radiation therapy dosimetry using magnetic resonance imaging of polymer gels
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Inhibitory mikrotubul w terapii przeciwnowotworowej = Inhibitors of microtubule in cancer therapy
PublicationW artykule opisano inhibitory mikrotubul, różnorodne związki chemiczne, znajdujące się w zaawansowanych przedklinicznych i wstępnych badaniach klinicznych. Pośród nich na uwagę zasługują półsyntetyczne analogi taksolu, substancje pochodzenia naturalnego, takie jak: epotilony, kombretastatyny, kolchinoidy, dolastatyny oraz syntetyczne związki o niskim ciężarze czasteczkowym: heterokombretastatyny, sulfonamidy, fenostatyny, pochodne...
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The effect of renal replacement therapy on the concentration of selected arachidonic acid derivatives
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COVID-19: Is There Evidence for the Use of Herbal Medicines as Adjuvant Symptomatic Therapy?
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Selection of physiological parameters for optoelectronic system supporting behavioral therapy of autistic children
PublicationIn this article the procedure of selection of physiological parameters for optoelectronic system supporting behavioral therapy of autistic children is proposed. Authors designed and conducted an experiment in which a group of 30 health volunteers (16 females and 14 males) were examined. Under controlled conditions people were exposed to a stressful situation caused by the picture or sound (1kHz constant sound, which was gradually...
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Binocular Vision Impairments Therapy Supported By Contactless Eye-gaze Tracking System
PublicationBinocular vision impairments often result in partial or total loss of stereoscopic vision. The lack of binocular vision is a serious vision impairment that deserves more attention. Very important result of the binocular vision impairments is a binocular depth perception. This paper describes also a concept of a measurement and therapy system for the binocular vision impairments by using eye-gaze tracking system.
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Limiting futile therapy as part of end-of-life care in intensive care units
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Artificial intelligence models in prediction of response to cardiac resynchronization therapy: a systematic review
PublicationThe aim of the presented review is to summarize the literature data on the accuracy and clinical applicability of artificial intelligence (AI) models as a valuable alternative to the current guidelines in predicting cardiac resynchronization therapy (CRT) response and phenotyping of patients eligible for CRT implantation. This systematic review was performed...
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Possiblities of application of recombined lysostaphin as an alternative agent in the therapy of Staphylococcus aureus mastitis
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The role of oat products in the prevention and therapy of type 2 diabetes, hypercholesterolemia and obesity
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Application of the laser diode with central wavelength 975 nm for the therapy of neurofibroma and hemangiomas
PublicationThis paper presents newly developed dermatological laser (with central wavelength 975 nm) for application in therapies requiring deep penetration of tissue, e.g. cutaneous (dermal) neurofibroma (Recklinghausen disease) and hemangiomas. This laser can work either in pulse or continues wave mode. Laser radiation is transmitted toward the application region by optical fiber with a diameter of 0.6 mm. The compact design of the laser...
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Investigating the disease‐modifying properties of sclerotiorin in Alzheimer's therapy using acetylcholinesterase inhibition
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Surfactant replacement therapy as promising treatment for COVID-19: an updated narrative review
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Serum MicroRNAs as Xerostomia Biomarkers in Patients With Oropharyngeal Cancer Undergoing Radiation Therapy
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Recent progress in the engineering of multifunctional colloidal nanoparticles for enhanced photodynamic therapy and bioimaging
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Therapy with CD4+CD25+ T regulatory cells – should we be afraid of cancer?
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Reasons for the discontinuation of therapy of personal insulin pump in children with type 1 diabetes
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Radiation Therapy-Induced Changes in Serum Lipidome of Head and Neck Cancer Patients
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Photophysical properties and photocytotoxicity of novel phthalocyanines – potentially useful for their application in photodynamic therapy
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More is Less? Optimal Combination Therapy for Adequate Blood Pressure Lowering in Hypertension
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Potential application of pure silica optical flat fibers for radiation therapy dosimetry
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Interactions of Bacteriophages with Animal and Human Organisms—Safety Issues in the Light of Phage Therapy
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Investigating the disease- modifying properties of sclerotiorin in Alzheimer's therapy using acetylcholinesterase inhibition
PublicationAlzheimer's disease (AD) is a progressive neurodegenerative disorder caused due to the damage and loss of neurons in specific brain regions. It is the most common form of dementia observed in older people. The symptoms start with memory loss and gradually cause the inability to speak and do day-to-day activities. The cost of caring for those affected individuals is huge and is probably beyond most developing countries capability....
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Phage therapy as a novel strategy in the treatment of urinary tract infections caused by E. coli
PublicationUrinary tract infections (UTIs) are regarded as one of the most common bacterial infections affecting millions of people, in all age groups, annually in the world. The major causative agent of complicated and uncomplicated UTIs are uropathogenic E. coli strains (UPECs). Huge problems with infections of this type are their chronicity and periodic recurrences. Other disadvantages that are associated with UTIs are accompanying complications...
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The Use of Physical Therapy Procedures in the Treatment of Soft Tissue Injuries in a Horse: A Case Study
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Comparison of conventional tacrolimus versus prolong release formula as initial therapy in heart transplantation
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Use of optical skin phantoms for preclinical evaluation of laser efficiency for skin lesion therapy
PublicationSkin lesions are commonly treated using laser heating. However, the introduction of new devices into clinical practice requires evaluation of their performance. This study presents the application of optical phantoms for assessment of a newly developed 975-nm pulsed diode laser system for dermatological purposes. Such phantoms closely mimic the absorption and scattering of real human skin (although not precisely in relation to...