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Efficacy and safety of B-cell receptor signaling pathway inhibitors in relapsed/refractory chronic lymphocytic leukemia: a systematic review and meta-analysis of randomized clinical trials
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Assessment of Clinical Usefulness of Resting Electrocardiogram (PH-ECG Score) in Monitoring the Efficacy of Balloon Pulmonary Angioplasty (BPA) in Patients with Chronic Thromboembolic Pulmonary Hypertension (CTEPH)
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Perceived Awareness of Clozapine associated with Socio- Demographic status, clinical, and side effect profile among patients from Mental Health Hospital, Taif, Saudi Arabia
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Pre-clinical toxicology and pathology of 9-(2'-hydroxyethylamino)-4-methyl-1-nitroacridine (C-1748), a novel anti-cancer agent in male Beagle dogs
PublicationPraca zawiera wyniki badań przedklinicznych i morfologicznych pochodnej akrydyny o symbolu C-1748 przeprowadzonych na psach. Wyznaczono maksymalną dawkę tolerowaną oraz przeprowadzono analizy zmiany składu krwi i morfologii jej komórek, pracy aminotransferaz, fosfokinaz, fosfataz i innych enzymów funkcjonalnych. Obserwowano też zachowanie się zwierząt. Stwierdzono, że związek ten wykazuje stosunkowo niską toksyczność, co przy obserwowanej...
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Perceived Awareness of Clozapine associated with Socio- Demographic status, clinical, and side effect profile among patients from Mental Health Hospital, Taif, Saudi Arabia
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Patient-Reported Quality of Life versus Physical Examination in Treating Temporomandibular Disorders with Intra-Articular Platelet-Rich Plasma Injections: An Open-Label Clinical Trial
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The Influence of SARS-CoV-2 Variants B.1.1.7 and B.1.617.2 on a Different Clinical Course and Severity of COVID-19 in Children Hospitalized in 2021 Compared With 2020
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P4604Insights into left ventricular remodelling and clinical outcomes after Wharton's jelly multipotent stem cells transcoronary administration in a pilot cohort of CIRCULATE-AMI Trial (NCT03404063)
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A Method of Lathe Checks Measurement; SMOF device and its software
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Albumin–Hyaluronan Interactions: Influence of Ionic Composition Probed by Molecular Dynamics
PublicationThe lubrication mechanism in synovial fluid and joints is not yet fully understood. Nevertheless, intermolecular interactions between various neutral and ionic species including large macromolecular systems and simple inorganic ions are the key to understanding the excellent lubrication performance. An important tool for characterizing the intermolecular forces and their structural consequences is molecular dynamics. Albumin...
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The Quality of Air in Polish Health Resorts with an Emphasis on Health on the Effects of Benzo(a)pyrene in 2015–2019
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Automatic music genre classification based on musical instrument track separation / Automatyczna klasyfikacja gatunku muzycznego wykorzystująca algorytm separacji dźwięku instrumentó muzycznych
PublicationThe aim of this article is to investigate whether separating music tracks at the pre-processing phase and extending feature vector by parameters related to the specific musical instruments that are characteristic for the given musical genre allow for efficient automatic musical genre classification in case of database containing thousands of music excerpts and a dozen of genres. Results of extensive experiments show that the approach...
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The possibility of application of the potentiometric sensor with all-solid-state electrodes containing lipid-polymer membranes for classification of tested black leaf teas in terms of their quality
PublicationPotentiometric sensor with all-solid-state electrodes containing lipid-polymer membranes for a set of black leaf teas coming from four countries (China, India, Sri Lanka and Kenia) classification was applied. The tested tea samples were reassigned to quality classes marked with numbers I–V according to the information available. The sensor results of tea samples are presented in the form of radar charts. It was observed that, in...
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Clinical and Epidemiological Characteristics of 1283 Pediatric Patients with Coronavirus Disease 2019 during the First and Second Waves of the Pandemic—Results of the Pediatric Part of a Multicenter Polish Register SARSTer
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Performance of electrochemical immunoassays for clinical diagnostics of SARS-CoV-2 based on selective nucleocapsid N protein detection: Boron-doped diamond, gold and glassy carbon evaluation
PublicationThe 21st century has already brought us a plethora of new threats related to viruses that emerge in humans after zoonotic transmission or drastically change their geographic distribution or prevalence. Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) was first spotted at the end of 2019 to rapidly spread in southwest Asia and later cause a global pandemic, which paralyzes the world since then. We have designed novel...
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Advanced Agent Identification With Fluctuation-Enhanced Sensing
PublicationPraca przedstawia wyniki szeregu zaawansowanych algorytmów przetwarzania sygnałów losowych obserwowanych w sensorach gazu typu Taguchi Gas Sensors. Stwierdzono, że proponowane metody pozwalają wykrywać bardziej efektywnie obecność wielu różnych gazów. W celu detekcji zastosowano głównie funkcje spektrum i bispektrum.
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Gas sensing by resistance fluctuations in PdxWO3 nanoparticle films.
PublicationPrzedstawiono wyniki badań sensorów gazu wykonanych z nanocząstek WO3 z dodatkiem Pd. Stwierdzono, że badanie fluktuacji rezystancji tych sensorów może istotnie zwiększyć czułość wykrywania gazu w porównaniu z obserwacją wyłącznie rezystancji stałoprądowej.
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Fluctuation enhanced gas sensing with WO3-based nanoparticle gas sensors modulated by UV light at selected wavelengths
PublicationThe sensitivity and selectivity of WO3-based gas sensors can be enhanced by UV-irradiation-induced modulation, especially if different wavelengths are employed. We used fluctuation-enhanced gas sensing, based on measurements of resistance fluctuations in the gas sensor, to study the effects of such modulation on the noise intensity for ambient atmospheres of synthetic air without and with additions of small amounts of ethanol,...
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Optimizing of MALDI-ToF-based low-molecular-weight serum proteome pattern analysis in detection of breast cancer patients; the effect of albumin removal on classification performance.
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Using Isolation Forest and Alternative Data Products to Overcome Ground Truth Data Scarcity for Improved Deep Learning-based Agricultural Land Use Classification Models
PublicationHigh-quality labelled datasets represent a cornerstone in the development of deep learning models for land use classification. The high cost of data collection, the inherent errors introduced during data mapping efforts, the lack of local knowledge, and the spatial variability of the data hinder the development of accurate and spatially-transferable deep learning models in the context of agriculture. In this paper, we investigate...
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Novel 2-(2-arylmethylthio-4-chloro-5-methylbenzenesulfonyl)-1-(1,3,5-triazin-2-ylamino)guanidine derivatives: Inhibition of human carbonic anhydrase cytosolic isozymes I and II and the transmembrane tumor-associated isozymes IX and XII, anticancer activity, and molecular modeling studies
PublicationA series of novel 2-(2-arylmethylthio-4-chloro-5-methylbenzenesulfonyl)-1-(6-substituted-4-chloro-1,3,5-triazin-2-ylamino)guanidine derivatives 9–20 have been synthesized by substitution of chlorine atom at the 1,3,5-triazine ring in compounds 5–8 with 3- or 4-aminobenzenesulfonamide and 4-(aminomethyl)benzenesulfonamide hydrochloride. All the synthesized compounds were evaluated for their inhibitory activity toward hCA I, II,...
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Oxidation Products of 5-Methylcytosine are Decreased in Senescent Cells and Tissues of Progeroid Mice
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Human CYP2 family of cytochrome P-450 takes part in metabolism of two acridine antitumor agents, C-1311 and C-1748, selected for I phase of clinical trials
PublicationPraca zawiera wyniki badań metabolicznej transformacji przeciwnowotworowych pochodnych akrydyny wobec zestawu 16 prób enzymów mikrosomalnych, pochodzących z wątroby 16 różnych pacjentów. Wykazano, że za metabolizm tych związków u człowieka odpowiedzialne są głównie izoenzymy z rodziny CYP2.
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Synthesis and structure analysis of ferrocene‐containing pseudopeptides
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Comparison of two doses of intravenous temsirolimus in patients with relapsed/refractory mantle cell lymphoma
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Odróżnienie brodawkowatego raka tarczycy od tkanki nienowotworowej w oparciu o profilowanie lipidów metodą MALDI-MSI
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The Recent Past and Possible Futures of Citizen Science: Final Remarks
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Towards development of sustainable lightweight 3D printed wall building envelopes – Experimental and numerical studies
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Акустическое изображение омонима этнического языка как входной элемент формальной классификации межъязыковой омонимии [The acoustic image of ethnic homonyms as an input element in formal classification of interlinguistic homonymy]
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Акустическое изображение омонима этнического языка как входной элемент формальной классификации межъязыковой омонимии [The acoustic image of ethnic homonyms as an input element in formal classification of interlinguistic homonymy]
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Circular Dichroism Imaging: Mapping the Local Supramolecular Order in Thin Films of Chiral Functional Polymers
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On the selectivity of nanostructured semiconductor gas sensors
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Activation of the Normal Human Skin Cells by a Portable Dielectric Barrier Discharge-Based Reaction-Discharge System of a Defined Gas Temperature
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Soil pH effects on the comparative toxicity of dissolved zinc, non-nano and nano ZnO to the earthwormEisenia fetida
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ROSANNE Project: New Procedure for Noise Characterisation of Road Surfaces in Europe
PublicationROSANNE is a collaborative project in the 7th EU Framework Programme which aims at harmonising measurement methods for skid resistance, noise emission and rolling resistance of road pavements as a preparation for standardization. The project started in November 2013 and is developing and improving standards in the field of working group CEN/TC 227/WG 5. Regarding the influence of the pavement on the road traffic noise emission,...
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Accurate, Direct, and High-Throughput Analyses of a Broad Spectrum of Endogenously Generated DNA Base Modifications with Isotope-Dilution Two-Dimensional Ultraperformance Liquid Chromatography with Tandem Mass Spectrometry: Possible Clinical Implication
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Hybrid cross-linked chitosan/protonated-proline:glucose DES membranes with superior pervaporation performance for ethanol dehydration
PublicationThis work explores a protonated L-proline:glucose (molar ratio 5:1) deep eutectic solvent (DES) in fabricating biopolymer membranes utilizing chitosan (CS). Initially, the miscibility of CS and DES to prepare homogeneous dense blend membranes has been investigated. Different techniques, such as scanning electron microscopy, contact angle (CA), atomic force microscopy (AFM), Fourier transformed infrared spectroscopy (FTIR) and swelling...
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Fluctuation-Enhanced Sensing with Organically Functionalized Gold Nanoparticle Gas Sensors Targeting Biomedical Applications
PublicationDetection of volatile organic compounds is a useful approach to non-invasive diagnosis of diseases through breath analysis. Our experimental study presents a newly developed prototype gas sensor, based on organically-functionalized gold nanoparticles, and results on formaldehyde detection using fluctuation-enhanced gas sensing. Formaldehyde was easily detected via intense fluctuations of the gas sensor’s resistance, while the cross-influence...
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New approaches for improving selectivity and sensitivity of resistive gas sensors: a review
PublicationPurpose – This paper aims to present the methods of improving selectivity and sensitivity of resistance gas sensors. Design/methodology/approach – This paper compares various methods of improving gas sensing by temperature modulation, UV irradiation or fluctuation-enhanced sensing. The authors analyze low-frequency resistance fluctuations in commercial Taguchi gas sensors and the recently developed tungsten trioxide (WO3) gas-sensing...
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Pyriculins A and B, two monosubstituted hex-4-ene-2,3-diols and other phytotoxic metabolites produced by Pyricularia grisea isolated from buffelgrass (Cenchrus ciliaris )
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Venetoclax for Patients With Chronic Lymphocytic Leukemia With 17p Deletion: Results From the Full Population of a Phase II Pivotal Trial
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Lighting conditions in home office and occupant’s perception: Exploring drivers of satisfaction
PublicationThis paper depicts lighting home office conditions within different countries and continents, emphasizing the user’s satisfaction with the visual environment. The scope of this article is to investigate the drivers of participants’ satisfaction with the lighting conditions at the home office. The study was developed by a team of international experts working together on Subtask A: User perspective and requirements, Task 61 IEA...
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Retained features of embryonic metabolism in the adult MRL mouse
PublicationThe MRL mouse is an inbred laboratory strain that was derived by selective breeding in 1960 from the rapidly growing LG/J (Large) strain. MRL mice grow to nearly twice the size of other commonly used mouse strains, display uncommonly robust healing and regeneration properties, and express later onset autoimmune traits similar to Systemic Lupus Erythematosis. The regeneration trait (heal) in the MRL mouse maps to 14-20 quantitative...
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Diurnal variability of atmospheric water vapour, precipitation and cloud top temperature across the global tropics derived from satellite observations and GNSS technique
PublicationThe diurnal cycle of convection plays an important role in clouds and water vapour distribution across the global tropics. In this study, we utilize integrated moisture derived from the global navigation satellite system (GNSS), satellite precipitation estimates from TRMM and merged infrared dataset to investigate links between variability in tropospheric moisture, clouds development and precipitation at a diurnal time scale. Over...
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The neuroprotective activity of new phenylalanine-based AMPA receptor antagonists
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ACEI and ARB — Each Unique RAAS Inhibitors
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Novel applications of noise in sensing and communications
PublicationPrzedstawiono zaproponowane w ostatnich latach sposoby wykorzystania szumów do wykrywania gazów, jako źródła informacji o atmosferze otaczającej czujnik. Ponadto, przedstawiono możliwości wykorzystania zjawisk losowych do bezpiecznej komunikacji.
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Detecting harmful gases using fluctuation-enhanced sensing with Taguchi sensors
PublicationTechniki sensorowe powinny być nie tylko wszechstronne ale także poprawiać dostarczaną informację.Artykuł przedstawia nowe podejście do analizy sygnałów obserwowanych podczas wykrywania gazów. Wykorzystuje się całe pasmo częstotliwości obserwowanych fluktuacji rezystancji sensora, w przecwieństwie do klasycznego podejścia wykorzystującego tylko obserwacje zmian rezystancji stałoprądowej. Nowe podej[cie pozwala zredukować liczbę...
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Fluctuation-Enhanced Sensing for Biological Agent Detection and Identification
PublicationPrzedstawiono wcześniejsze wyniki badań dotyczące trzech różnych sposobów wykrywania obecności substancji biologicznych za pomocą zjawisk fluktuacyjnych: 1) wirusów wnikających do komórek, 2) zapachów emitowanych przez mikroby, 3) rozkładu widma i wartości chwilowych szumów podczas rozpraszania światła używanego do wykrywania zarodników na podstawie wyznaczenia współczynnika dyfuzji opisująceo ich ruch.We survey and show our earlier...
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Muscle Cell Morphogenesis, Structure, Development and Differentiation Processes Are Significantly Regulated during Human Ovarian Granulosa Cells In Vitro Cultivation
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