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The INTERSALT Study and the complex relationship between salt intake and blood pressure
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Blood Pressure celebrates 20 years of dedication to Nordic hypertension research
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Application of GC-MS/MS technique for the determination of benzodiazepines in blood samples
PublicationAbstract Benzodiazepines (BZD) are widely used as pharmaceuticals in medicine. However, due to psychostimulatory effect of BZD, in the last decade, they are more and more often used as drugs of abuse. These compounds produce similar effects to classical illicit drugs and are sold as “legal” alternatives to them as new psychoactive substances (NPS). Currently new BZD, named designer benzodiazepines (DBZD), are synthesized each year...
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An Insight into the Stages of Ion Leakage during Red Blood Cell Storage
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Effects of local anesthetics on the respiratory burst of cord blood neutrophils in vitro
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Anaerobic Exercise-Induced Activation of Antioxidant Enzymes in the Blood of Women and Men
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Brain/blood distribution described by a combination of partition coefficient and molecular mass
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An electrochemical interface for direct analysis of amlodipine in tablets and human blood samples
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Resistance Training with Blood Flow Restriction and Ocular Health: A Brief Review
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The Influence of Winter Swimming on Oxidative Stress Indicators in the Blood of Healthy Males
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Sex differences in excess and reservoir arterial blood pressures as markers of phenotype
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The Effect of Herbal Supplements on Blood Pressure: Systematic Review and Meta-Analysis
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Directional surface plasmon-coupled emission - application for an immunoassay in whole blood
PublicationZaprezentowano badania fluorescencji znakowanej barwnikiem immunoglobuliny G, na powierzchni srebra.
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Numerical investigation of multiphase blood flow coupled with lumped parameter model of outflow
PublicationPurpose The purpose of this paper is the application of the computational fluid dynamics model simulating the blood flow within the aorta of an eight-year-old patient with Coarctation of Aorta. Design/methodology/approach The numerical model, based on commercial code ANSYS Fluent, was built using the multifluid Euler–Euler approach with the interaction between the phases described by the kinetic theory of granular flow (KTGF). Findings A...
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Machine-aided detection of SARS-CoV-2 from complete blood count
PublicationThe current gold standard for SARS-CoV-2 detection methods lacks the functionality to perform population screening. Complete blood count (CBC) tests are a cost-effective way to reach a wide range of people – e.g. according to the data of the Central Statistical Office of Poland from 2016, there are 3,000 blood diagnostic laboratories in Poland, and 46% of Polish people have at least one CBC test per year. In our work, we show...
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Non-invasive blood glucose monitoring with Raman spectroscopy: prospects for device miniaturization
PublicationThe number of patients with diabetes has reached over 350 million, and still continues to increase. The need for regular blood glucose monitoring sparks the interest in the development of modern detection technologies. One of those methods, which allows for noninvasive measurements, is Raman spectroscopy. The ability of infrared light to penetrate deep into tissues allows for obtaining measurements through the skin without its...
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Challenges in oscillometric blood pressure measurement in atrial fibrillation: looking for practical solutions
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More is Less? Optimal Combination Therapy for Adequate Blood Pressure Lowering in Hypertension
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Determination of MDPBP in postmortem blood samples by gas chromatography coupled with mass spectrometry
PublicationMDPBP (1-(3,4-methylenedioxyphenyl)-2-(1-pyrrolidinyl)-1-butanone) is a new psychoactive substance sold on the black market. It has been a controlled drug of abuse in Poland and China since 2015 as some toxic and fatal cases connected with use of synthetic cathinone derivatives were observed. The fatal case outlined here concerns a 19 year-old man, who was found dead with an envelope containing white powder lying nearby the cadaver....
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Modeling of subarachnoid space width change caused by blood circulation in brain vessels
PublicationThe subarachnoid space is an anatomic space, lying in the central nervous system, between the arachnoid membrane and the pia mater. It is filled with cerebrospinal fluid, which protects and nourishes the brain. The pathological disorder of the subarachnoid space (i.e. increase or decrease of its width) a ects the nervous system. Therefore, it is important to diagnose the width changes of the subarachnoid space. One way to support...
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Gender-Related Differences in Trimethylamine and Oxidative Blood Biomarkers in Cardiovascular Disease Patients
PublicationGender differences in the burden of cardiovascular disease (CVD) have been observed worldwide. In this study, plasmatic levels of trimethylamine (TMA) and blood oxidative biomarkers have been evaluated in 358 men (89 controls and 269 CVD patients) and 189 women (64 control and 125 CVD patients). The fluorescence technique was applied to determine erythrocyte membrane fluidity using 1,6-diphenyl-1,3,5-hexatriene (DPH) and Laurdan,...
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Multiscale model for blood flow after a bileaflet artificial aortic valve implantation
PublicationCardiovascular diseases are the leading cause of mortality in the world, mainly due to atherosclerosis and its consequences. The article presents the numerical model of the blood flow through artificial aortic valve. The overset mesh approach was applied to simulate the valve leaflets motion and to realize the moving mesh, in the aortic arch and the main branches of cardiovascular system. To capture the cardiac system’s response...
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Impact of slow breathing on the blood pressure and subarachnoid space width oscillations in humans
PublicationThe aim of the study was to assess cardiac and respiratory blood pressure (BP) and subarachnoid space (SAS) width oscillations during the resting state for slow and fast breathing and breathing against inspiratory resistance. Experiments were performed on a group of 20 healthy volunteers (8 males and 12 females; age 25.3 ± 7.9 years; BMI = 22.1 ± 3.2 kg/m2). BP and heart rate (HR) were measured using continuous finger-pulse photoplethysmography....
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Differentially expressed proteins in the blood serum of piglets in response to a diet supplemented with inulin
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Comparison of Oxidative Stress/DNA Damage in Semen and Blood of Fertile and Infertile Men
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Blood glucose level as an insufficient indicator of feline diabetes mellitus: a case report
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The effects of nordic walking training on blood antioxidant defence in patients with intermittent claudication
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Changes in Non-Enzymatic Antioxidants in the Blood Following Anaerobic Exercise in Men and Women
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Foetal haemoglobin-blood cells (F-cells) as a feature of embryonic tumours (blastomas)
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Gender-Selective Interaction Between Aging, Blood Pressure, and Sympathetic Nerve Activity
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Resting sympathetic outflow does not predict the morning blood pressure surge in hypertension
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Relationship Between Muscle Sympathetic Nerve Activity and Diurnal Blood Pressure Profile
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Interactive Effect of Heart Rate and Muscle Sympathetic Nerve Activity on Blood Pressure
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Enantioselective sensing of (S)-Thalidomide in blood plasma with a chiral naphthalene diimide derivative
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The protocol for using elastic wall model in modeling blood flow within human artery
PublicationMedical diagnostic tools will play a major role in the future for an effective patient treatment and reduction their mortality, related to the cardiovascular system diseases (CVDs). There is an urgent need for developing diagnostic procedure to be robust, reliable, accurate and efficient, in the framework of a paradigm shift. Application of numerical techniques is seen as a perspective tool for such purpose. Nevertheless, existing...
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Active dynamic thermography method for TRAM flap blood perfusion mapping in breast reconstruction
PublicationThis paper presents the new method of the transverse rectus abdominis musculocutaneous flap blood perfusion mapping based on the active dynamic thermography. The method is aimed at aiding a surgeon during breast reconstruction procedure. A pair of dTnorm and t90_10 parameters were used as parametric image descriptors of the flap blood perfusion. The method was tested on 38 patients that were subjected to breast reconstruction procedure....
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Modelling of subarachnoid space width changes in apnoea resulting as a function of blood flow parameters
PublicationDuring apnoea, the pial artery is subjected to two opposite physiological processes: vasoconstriction due to elevated blood pressure and vasorelaxation driven by rising pH in the brain parenchyma. We hypothesized that the pial artery response to apnoea may vary, depending on which process dominate. Apnoea experiments were performed in a group of 19 healthy, non-smoking volunteers (9 men and 10 women). The following parameters...
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COVID-19 severity forecast based on machine learning and complete blood count data
PublicationProper triage of COVID-19 patients is a key factor in eective case management, especially with limited and insucient resources. In this paper, we propose a machine-aided diagnostic system to predict how badly a patient with COVID-19 will develop disease. The prognosis of this type is based on the parameters of commonly used complete blood count tests, which makes it possible to obtain data from a wide range of patients.We chose...
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COVID-19 severity forecast based on machine learning and complete blood count data
PublicationProper triage of COVID-19 patients is a key factor in eective case management, especially with limited and insucient resources. In this paper, we propose a machine-aided diagnostic system to predict how badly a patient with COVID-19 will develop disease. The prognosis of this type is based on the parameters of commonly used complete blood count tests, which makes it possible to obtain data from a wide range of patients.We chose...
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Response of a New Low-Coherence Fabry-Perot Sensor to Hematocrit Levels in Human Blood
PublicationIn this paper, a low-coherence Fabry-Perot sensor with a spectrally measured signal processing response to the refractive index of liquids is presented. Optical fiber sensors are potentially capable of continuous measuring hematocrit levels in blood. Low-coherence Fabry-Perot interferometric sensors offer a robust solution, where information about the measurand is encoded in the full spectrum of light reflected from the sensing...
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Which Target Blood Pressure in Year 2018? Evidence from Recent Clinical Trials
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Coupling between Blood Pressure and Subarachnoid Space Width Oscillations during Slow Breathing
PublicationThe precise mechanisms connecting the cardiovascular system and the cerebrospinal fluid (CSF) are not well understood in detail. This paper investigates the couplings between the cardiac and respiratory components, as extracted from blood pressure (BP) signals and oscillations of the subarachnoid space width (SAS), collected during slow ventilation and ventilation against inspiration resistance. The experiment was performed on...
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Mesenchymal Phenotype of CTC-Enriched Blood Fraction and Lymph Node Metastasis Formation Potential
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Response of a New Low-Coherence Fabry-Perot Sensor to Hematocrit Levels in Human Blood
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Spectroscopic Signature of Red Blood Cells in a D-Galactose-Induced Accelerated Aging Model
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Metabolic Gene Expression in the Muscle and Blood Parameters of Broiler Chickens Stimulated In Ovo with Synbiotics
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Blood plasma protein and lipid profile changes in calves during the first week of life
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Blood pressure disturbances and endothelial dysfunction markers in children and adolescents with type 1 diabetes
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Local anaesthetics upregulate nitric oxide generation in cord blood and adult human neutrophils
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Blood–brain barrier permeability mechanisms in view of quantitative structure–activity relationships (QSAR)
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