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Search results for: Ukraina
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AmiP from hyperthermophilic Thermus parvatiensis prophage is a thermoactive and ultrathermostable peptidoglycan lytic amidase
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Entrepreneurship Today: Selected Aspects
PublicationAt its very beginning, entrepreneurship was a purely economic notion. However, this growing interest in entrepreneurship-related problems prompted other sciences to participate in explaining the entrepreneurship phenomenon. Nowadays, entrepreneurship is analyzed through multiple theoretical lenses of economics, management, psychology, sociology – just to name a few. Therefore, it would be difficult to find a notion that could be...
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Fatty acyl benzamido antibacterials based on inhibition of DnaK-catalyzed protein folding
PublicationWe have reported that the hsp70 chaperone DnaK from Escherichia coli might assist protein folding by catalyzing the cis/trans isomerization of secondary amide peptide bonds in unfolded or partially folded proteins. In this study a series of fatty acylated benzamido inhibitors of the cis/trans isomerase activity of DnaK was developed and tested for antibacterial effects in E. coli MC4100 cells. Nα-[Tetradecanoyl-(4-aminomethylbenzoyl)]-l-asparagine...
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Dehydration converts DsbG crystal diffraction from low to high resolution
PublicationDiffraction quality crystals are essential for crystallographic studies of protein structure, and the production of poorly diffracting crystals is often regarded as a dead end in the process. Here we show a dramatic improvement of poorly diffracting DsbG crystals allowing high-resolution diffraction data measurement. Before dehydration, the crystals are fragile and the diffraction pattern is streaky, extending to 10 Å resolution....
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Challenges of Comparing Marine Microbiome Community Composition Data Provided by Different Commercial Laboratories and Classification Databases
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The first Polish cohort of adult patients with common variable immunodeficiency from four specialized centers: do we provide standards of care?
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Shorter Diagnostic Delay in Polish Adult Patients With Common Variable Immunodeficiency and Symptom Onset After 1999
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Structure and function of the Ts2631 endolysin of Thermus scotoductus phage vB_Tsc2631 with unique N-terminal extension used for peptidoglycan binding
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CSR at HEIs: Between Ignorance, Awareness and Knowledge
PublicationThe paper focuses on CSR education in Higher Education Institutions. It analyzes current approaches to this education and the enhancements already deployed in the international perspective. The main aim is to conceptualize CSRS education forms within the context of technology-oriented HEIs and propose the model for this education. This model has also been partially verified using the cases of four technical universities. This research...
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Przeciwdziałanie nielegalnej emigracji na granicy polsko-rosyjskiej w dobie członkostwa Polski w Unii Europejskiej
PublicationPrzeciwdziałaniu nielegalnej emigracji do państw Unii Europejskiej służą akty prawa unijnego i krajowego. Do najważniejszych unijnych aktów prawa należy zaliczyć: traktat o funkcjonowaniu Unii Europejskiej, program „Otwarta i bezpieczna Europa: realizacja założeń” oraz dyrektywy w sprawie przeciwdziałania nielegalnej migracji. Do polskich aktów prawnych należą ustawy: o cudzoziemcach, o udzielaniu cudzoziemcom ochrony na terytorium...
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Six Weeks of Calorie Restriction Improves Body Composition and Lipid Profile in Obese and Overweight Former Athletes
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Role of size scale of ZnO nanoparticles and microparticles on toxicity toward bacteria and osteoblast cancer cells
PublicationThe specific role of size scale, surface capping, and aspect ratio of zinc oxide (ZnO) particles on toxicity toward prokaryotic and eukaryotic cells was investigated. ZnO nano and microparticles of controlled size and mor- phology were synthesized by wet chemical methods. Cytotoxicity toward mammalian cells was studied using a human osteoblast cancer cell line and antibacterial activity using Gram-negative bacteria (Escherichia...
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Electrochemical performance of Co3O4/CeO2 electrodes in H2S/H2O atmospheres in a proton-conducting ceramic symmetrical cell with BaZr0.7Ce0.2Y0.1O3 solid electrolyte
PublicationThe electrochemical performance of Co3O4/CeO2 mixed oxide materials as electrodes, when exposed to H2S/H2O atmospheres, was examined employing a proton conducting symmetrical cell, with BaZr0.7Ce0.2Y0.1O3 (BZCY72) as the solid electrolyte. The impact of temperature (700–850 °C) and H2S concentration (0–1 v/v%) in steam-rich atmospheres (90 v/v% H2O) on the overall cell performance was thoroughly assessed by means of electrochemical...
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CPLFD-GDPT5: High-resolution gridded daily precipitation and temperature data set for two largest Polish river basins
PublicationThe CHASE-PL (Climate change impact assessment for selected sectors in Poland) Forcing Data–Gridded Daily Precipitation & Temperature Dataset–5 km (CPLFD-GDPT5) consists of 1951–2013 daily minimum and maximum air temperatures and precipitation totals interpolated onto a 5 km grid based on daily meteorological observations from the Institute of Meteorology and Water Management (IMGW-PIB; Polish stations), Deutscher Wetterdienst...
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Discovery and characterization of RecA protein of thermophilic bacterium Thermus thermophilus MAT72 phage Tt72 that increases specificity of a PCR-based DNA amplification
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A mobile loop order–disorder transition modulates the speed of chaperonin cycling
PublicationMolecular machines order and disorder polypeptides as they form and dissolve large intermolecular interfaces, but the biological significance of coupled ordering and binding has been established in few, if any, macromolecular systems. The ordering and binding of GroES co-chaperonin mobile loops accompany an ATP-dependent conformational change in the GroEL chaperonin that promotes client protein folding. Following ATP hydrolysis,...
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Asocjacje – jak gdyby, tak jakby…
PublicationKrzysztof Wróblewski prezentuje „In Touch / Anonymous”. (Twarz – jako maska, dłoń – jako dotyk i ślad) – dwa obrazy (olej na płótnie, wymiary: 146x228 cm) wraz z komentarzem: „W kuratorskim tekście do wystawy Asocjacje – jak gdyby, tak jakby zainteresował mnie cytat z teorii umysłu: jesteśmy świadomi umysłów innych ludzi i to ma wpływ na nasze poczynania i procesy umysłowe. Sztuka jako jedno z narzędzi komunikacji jest wysyłaniem...
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Molecular Characterization of a Novel Lytic Enzyme LysC from Clostridium intestinale URNW and Its Antibacterial Activity Mediated by Positively Charged N-Terminal Extension
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Electron-Induced Decomposition of Uracil-5-yl O-(N,N-dimethylsulfamate): Role of Methylation in Molecular Stability
PublicationThe incorporation of modified uracil derivatives into DNA leads to the formation of radical species that induce DNA damage. Molecules of this class have been suggested as radiosensitizers and are still under investigation. In this study, we present the results of dissociative electron attachment to uracil-5-yl O-(N,N-dimethylsulfamate) in the gas phase. We observed the formation of 10 fragment anions in the studied range of electron...
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Molecular Characterization of a DNA Polymerase from Thermus thermophilus MAT72 Phage vB_Tt72: A Novel Type-A Family Enzyme with Strong Proofreading Activity
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Increased Urinary C-Peptide and Albumin Excretion in Juvenile Borderline Hypertensives
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Novel Lytic Enzyme of Prophage Origin from Clostridium botulinum E3 Strain Alaska E43 with Bactericidal Activity against Clostridial Cells
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Molecular Strategy for Survival at a Critical High Temperature in Eschierichia coli
PublicationThe molecular mechanism supporting survival at a critical high temperature (CHT) in Escherichia coli was investigated. Genome-wide screening with a single-gene knockout library provided a list of genes indispensable for growth at 47°C, called thermotolerant genes. Genes for which expression was affected by exposure to CHT were identified by DNA chip analysis. Unexpectedly, the former contents did not overlap with the latter except...
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The Characteristics of New SSB Proteins from Metagenomic Libraries and Their Use in Biotech Applications
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Diamonds in the Mine. Strategies for the Cities in the Silesian Metropolitan Region. / Diamenty w kopalni. Strategie rozwoju dla miast śląskiego regionu metropolitalnego.
PublicationJan Olbrycht, poseł do Parlamentu Europejakiego, w swojej działalności związanej z rozwojem miast współpracuje z Towarzystwem Urbanistów Polskich, jednym z najstarszych stowarzyszeń urbanistów w Europie, które aktywnie działa od 1923 roku. Miałam przyjemność i zaszczyt reprezentować Zarząd Główny Towarzystwa w naszych ostatnich wspólnych przedsięwzięciach. W roku 2016 po konferencji „Miasto - Zarządzanie Miastem” corocznie...
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Euro 2012. Czy ten mecz można wygrać?
PublicationZbliżające się Mistrzostwa Europy w Piłce Nożnej, które w 2012 roku będą odbywały się na Ukrainie i w Polsce, od wielu lat budzą emocje, nie tylko wśród kibiców. Zaraz po ogłoszeniu wyników wyboru gospodarzy tej imprezy, pojawiło się wiele doniesień na temat korzyści gospodarczych, jakie ta impreza im przyniesie. Fala entuzjazmu trochę osłabła gdy okazało się ile musimy, jako kraj sporo zainwestować, aby te korzyści rzeczywiście...
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Novel Highly Thermostable Endolysin from Thermus scotoductus MAT2119 Bacteriophage Ph2119 with Amino Acid Sequence Similarity to Eukaryotic Peptidoglycan Recognition Proteins
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Coalition Shaping the Vaccination Landscape
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Activation mechanism and activity of globupain, a thermostable C11 protease from the Arctic Mid-Ocean Ridge hydrothermal system
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Biochemical Characterization and Validation of a Catalytic Site of a Highly Thermostable Ts2631 Endolysin from the Thermus scotoductus Phage vB_Tsc2631
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Crystal structure and initial characterization of a novel archaeal-like Holliday junction-resolving enzyme from Thermus thermophilus phage Tth15-6
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A Novel Cryptic Clostridial Peptide That Kills Bacteria by a Cell Membrane Permeabilization Mechanism
PublicationThis work reports detailed characteristics of the antimicrobial peptide Intestinalin (P30), which is derived from the LysC enzyme of Clostridium intestinale strain URNW. The peptide shows a broader antibacterial spectrum than the parental enzyme, showing potent antimicrobial activity against clinical strains of Gram-positive staphylococci and Gram-negative pathogens and causing between 3.04 ± 0.12 log kill for Pseudomonas aeruginosa...
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Fluoride content in the hair in dependence of the place of residence, sex, dietary habits and anthropometric data
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Intramolecular Proton Transfer in the Radical Anion of Cytidine Monophosphate Sheds Light on the Sensitivities of Dry vs Wet DNA to Electron Attachment-Induced Damage
PublicationSingle-strand breaks (SSBs) induced via electron attachment were previously observed in dry DNA under ultrahigh vacuum (UHV), while hydrated electrons were found not able to induce this DNA damage in an aqueous solution. To explain these findings, crossed electron-molecular beam (CEMB) and anion photoelectron spectroscopy (aPES) experiments coupled to density functional theory (DFT) modeling were used to demonstrate the fundamental...
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Seeking Optimal Nutrition for Healthy Body Mass Reduction Among Former Athletes
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Crystal structures of the Bacillus subtilis prophage lytic cassette proteins XepA and YomS
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Health-related quality of life data from a phase 3, international, randomized, open-label, multicenter study in patients with previously treated mantle cell lymphoma treated with ibrutinib versus temsirolimus
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Ibrutinib versus temsirolimus in patients with relapsed or refractory mantle-cell lymphoma: an international, randomised, open-label, phase 3 study
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Analysis of urinary cathepsin C for diagnosing Papillon–Lefèvre syndrome
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Going to extremes – a metagenomic journey into the dark matter of life
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Effects of hospital facilities on patient outcomes after cancer surgery: an international, prospective, observational study
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Global variation in postoperative mortality and complications after cancer surgery: a multicentre, prospective cohort study in 82 countries
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