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Search results for: MARKETING TERYTORIALNY
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Targeting yeast topoisomerase II by imidazo and triazoloacridinone derivatives resulting in their antifungal activity
PublicationFungal pathogens are considered as serious factors for deadly diseases and are a case of medical concern. Invasive fungal infections also complicate the clinical course of COVID-19, leading to a significant increase in mortality. Furthermore, fungal strains' multidrug resistance has increased the demand for antifungals with a different mechanism of action. The present study aimed to identify antifungal compounds targeting yeast...
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Antifungal Effect of Penicillamine Due to the Selective Targeting of L-Homoserine O-Acetyltransferase
PublicationDue to the apparent similarity of fungal and mammalian metabolic pathways, the number of established antifungal targets is low, and the identification of novel ones is highly desirable. The results of our studies, presented in this work, indicate that the fungal biosynthetic pathway of L-methionine, an amino acid essential for humans, seems to be an attractive perspective. The MET2 gene from Candida albicans encoding L-homoserine...
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Targeting mTORs by omega-3 fatty acids: A possible novel therapeutic strategy for neurodegeneration?
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Homoisocitrate dehydrogenase from Candida albicans: properties, inhibition, and targeting by an antifungal pro-drug
PublicationThe LYS12 gene from Candida albicans, coding for homoisocitrate dehydrogenase was cloned and expressed as a His-tagged protein in Escherichia coli. The purified gene product catalyzes the Mg2+- and K+-dependent oxidative decarboxylation of homoisocitrate to alpha-ketoadipate. The recombinant enzyme demonstrates strict specificity for homoisocitrate. SDS-PAGE of CaHIcDH revealed its molecular mass of 42.6±1 kDa, while in size-exclusion...
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Magdalena Brzozowska-Woś dr hab. inż.
PeopleMagdalena Brzozowska-Woś is a graduate of the Faculty of Management and Economics of the Gdańsk University of Technology (specialization: management systems). She is also a graduate of Postgraduate Studies in Advertising (Faculty of Management and Economics, GUT) and Postgraduate Studies in Public Relations (SWPS University of Humanities and Social Sciences). In the years 2000-2003, she cooperated with Panorama Internet sp. z o....
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Caderno Profissional de Marketing Unimep
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Journal of Global Scholars of Marketing Science
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International Journal of Pharmaceutical and Healthcare Marketing
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Journal of Nonprofit & Public Sector Marketing
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Asia Pacific Journal of Marketing and Logistics
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International Journal of Internet Marketing and Advertising
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International Review on Public and Nonprofit Marketing
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Journal of International Food and Agribusiness Marketing
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Management & Marketing-Challenges for the Knowledge Society
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Journal of Empirical Generalisations in Marketing Science
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International Journal of Sport Management and Marketing
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International Journal of Electronic Marketing and Retailing
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International Journal of Sports Marketing & Sponsorship
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Recherche et Applications en Marketing
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Retail and Marketing Review (South Africa)
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Journal of Digital and Social Media Marketing
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Redmarka. Revista de marketing aplicado
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Journal of Tourism, Heritage and Services Marketing
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SERRATE interacts with the nuclear exosome targeting (NEXT) complex to degrade primary miRNA precursors in Arabidopsis
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Fluctuation-Enhanced Sensing with Organically Functionalized Gold Nanoparticle Gas Sensors Targeting Biomedical Applications
PublicationDetection of volatile organic compounds is a useful approach to non-invasive diagnosis of diseases through breath analysis. Our experimental study presents a newly developed prototype gas sensor, based on organically-functionalized gold nanoparticles, and results on formaldehyde detection using fluctuation-enhanced gas sensing. Formaldehyde was easily detected via intense fluctuations of the gas sensor’s resistance, while the cross-influence...
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Maria Jastrzębska dr hab.
PeopleMaria Jastrzębska is an employee of the Department of Finance. She is the author of over 170 publications, including 8 monographs - Financial Management of Municipalities. Theoretical aspects; Budgetary policy of local government units; Debt management of local government units; Finances of local government units; Risk management in the activity of local government units with special consideration of catastrophic risk (co-author...
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Uwagi o usługach w grupie kierunków ekonomicznych w 2001 r. Dydaktyka marketingu w wyższej uczelni technicznej.
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JOURNAL OF DRUG TARGETING
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Inhibitors and Antibody Fragments as Potential Anti-Inflammatory Therapeutics Targeting Neutrophil Proteinase 3 in Human Disease
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Folic acid-conjugated mesoporous silica particles as nanocarriers of natural prodrugs for cancer targeting and antioxidant action
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Level and significance of European Union means in the budgets of non-urban poviats of Pomeranian voivodeship
PublicationJednym z warunków prowadzenia działań mających na celu rozwój obszaru jest posiadanie środków finansowych pozwalających realizować zadania, które ten rozwój determinują. Środki te pochodzić mogą z różnych źródeł. Jednym z tych źródeł jest wsparcie pochodzące z budżetu Unii Europejskiej przyznawane w określonych ramach czasowych zwanych okresem programowania. Polska już po raz drugi korzystać może z pomocy udzielanej w tej formie....
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International Journal of Nonprofit and Voluntary Sector Marketing
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International Journal of Marketing Communication and New Media
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International Journal of Applied Services Marketing Perspectives
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Journal of Direct, Data and Digital Marketing Practice
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International Journal of Customer Relationship Marketing and Management
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Journal of Marketing and Consumer Behaviour in Emerging Markets
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Marketing, Zeitschrift fur Forschung und Praxis
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Profilowanie dzieci dla celu marketingu cyfrowego w europejskim prawie ochrony danych osobowych a konieczność realizacji najlepiej pojętego interesu dziecka
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Effective Targeting of Colon Cancer Cells with Piperine Natural Anticancer Prodrug Using Functionalized Clusters of Hydroxyapatite Nanoparticles
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DNA structure and integrity checkpoints in the cell cycle and their role in drug targeting and resistance of tumor cells to anticancer treatment
PublicationW artykule dokonaliśmy przeglądu literatury dotyczącej różnych typów uszkodzeń DNA indukowanych przez różne czynniki terapeutyczne w komórkach nowotworowych. Omówiliśmy także w jaki sposób aktywują różne typy punktów kontrolnych w cyklu komórkowym i w jaki sposób punkty te są regulowane przez inne szlaki sygnalizacji wewnątrzkomórkowej takie jak szlaki naprawy uszkodzeń DNA, stresu komórkowego i śmierci-przeżycia. W szczególności...
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A new 1-nitro-9-aminoacridine derivative targeting yeast topoisomerase II able to overcome fluconazole-resistance
PublicationFungal resistance remains a significant threat and a leading cause of death worldwide. Thus, overcoming microbial infections have again become a serious clinical problem. Although acridine derivatives are widely analyzed as anticancer agents, only a few reports have demonstrated their antifungal activity. In an effort to develop biologically active antifungals, twelve novel C-857 (9-(2′ -hydroxyethylamino)-1-nitroacridine) and...
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Australian and New Zealand Marketing Academy Conference
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Targeting of FLT3-ITD kinase contributes to high selectivity of imidazoacridinone C-1311 against FLT3-activated leukemia cells
PublicationDrugs targeting receptor tyrosine kinase FLT3 are of particular interest since activating FLT3-internal tandem duplication (ITD) mutations abundantly occur in fatal acute myeloid leukemias (AMLs). Imidazoacridinone C-1311, a DNA-reactive inhibitor of topoisomerase II, has been previously shown to be a potent and selective inhibitor of recombinant FLT3. Here, we expand those findings by studying its effect on leukemia cells with...
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9,10-Dioxoanthracenyldithiocarbamates effectively inhibit the proliferation of non-small cell lung cancer by targeting multiple protein tyrosine kinases
PublicationAnthraquinones have attracted considerable interest in the realm of cancer treatment owing to their potent anticancer properties. This study evaluates the potential of a series of new anthraquinone derivatives as anticancer agents for non-small-cell lung cancer (NSCLC). The compounds were subjected to a range of tests to assess their cytotoxic and apoptotic properties, ability to inhibit colony formation, pro-DNA damage functions,...
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Foliate-Targeting Quantum Dots-β-Cyclodextrin Nanocarrier for Efficient Delivery of Unsymmetrical Bisacridines to Lung and Prostate Cancer Cells
PublicationTargeted drug delivery by nanocarriers molecules can increase the efficiency of cancer treatment. One of the targeting ligands is folic acid (FA), which has a high affinity for the folic acid receptors, which are overexpressed in many cancers. Herein, we describe the preparation of the nanoconjugates containing quantum dots (QDs) and β-cyclodextrin (β-CD) with foliate-targeting properties for the delivery of anticancer compound...
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Journal of Research in Interactive Marketing
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Kształtowanie nowego wizerunku miast delty Wisły
PublicationObszar delty wisły został dotknięty szeregiem negatywnych zjawisk będących następstwem burzliwej historii tych ziem. ważnym elementem działań naprawczych jest zmiana negatywnego wizerunku miejsca oraz wzmoicnienie poczucia tożsamości terytorialnej wśród (w większości napływowej) społeczności lokalnej.artykuł przedstawia dotychczasowe dościwadczenia oraz perspektywy dalszych działań wybranych miast delty wisły dotyczących wykorzystania,...
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Dorota Dominika Kamrowska-Załuska dr hab. inż. arch.
PeopleProf. Dorota Kamrowska-Zaluska, architect and urban planner, Associate Professor and Director of mid-career program on Urban development and management of metropolitan areas, at the Department of Urban Design and Regional Planning at Faculty of Architecture, Gdansk University of Technology; Visiting Scholar and Research Fellow at several research institutions incl. Massachusetts Institute of Technology (2013), Charted Urban Planner...
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Zeszyty Naukowe Politechniki Rzeszowskiej. Zarządzanie i Marketing
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