Anna Stanisławska-Sachadyn - Publikacje - MOST Wiedzy

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  • Association of Genes Related to Oxidative Stress with the Extent of Coronary Atherosclerosis
    Publikacja

    - Life - Rok 2020

    Oxidative stress is believed to play a critical role in atherosclerosis initiation and progression. In line with this, in a group of 1099 subjects, we determined eight single nucleotide polymorphisms (SNPs) related to oxidative stress (PON1 c.575A>G, MPO c.463G>A, SOD2 c.47T>C, GCLM c.590C>T, NOS3 c.894G>T, NOS3 c.786T>C, CYBA c.214C>T, and CYBA c.932A>G) and assessed the extent of atherosclerosis in coronary arteries based on...

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  • NADPH Oxidase Gene Polymorphism is Associated with Mortality and Cardiovascular Events in 7-Year Follow-Up
    Publikacja
    • M. Racis
    • W. Sobiczewski
    • A. Stanisławska-Sachadyn
    • M. Wirtwein
    • E. Bluj
    • M. Nedoszytko
    • J. Borzyszkowska
    • J. Limon
    • A. Rynkiewicz
    • M. Gruchała

    - Journal of Clinical Medicine - Rok 2020

    The CYBA gene encodes the regulatory subunit of NADPH oxidase, which maintains the redox state within cells and in the blood vessels. That led us to investigate the course of coronary artery disease (CAD) with regards to CYBA polymorphisms. Thus, we recruited 1197 subjects with coronary atherosclerosis and observed them during 7-year follow-up. Three CYBA polymorphisms: c.214C>T (rs4673), c.-932G>A (rs9932581), and c.*24G>A (1049255)...

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Rok 2019
  • Folate/homocysteine metabolism and lung cancer risk among smokers
    Publikacja

    - PLOS ONE - Rok 2019

    Background: Folate and homocysteine are involved in DNA synthesis and methylation processes, which are deregulated during carcinogenesis. Objectives: The aim of this study was to assess the relationship between folate/homocysteine concentrations, the functional polymorphisms of folate/homocysteine genes and lung cancer risk among cigarette smokers. Study design: The study included 132 lung cancer patients and 396 controls from...

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