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Substrate Reduction Therapies for Mucopolysaccharidoses
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Lysosome Alterations in the Human Epithelial Cell Line HaCaT and Skin Specimens: Relevance to Psoriasis
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From Bioink to Tissue: Exploring Chitosan-Agarose Composite in the Context of Printability and Cellular Behaviour
PublikacjaThis study presents an innovative method for producing thermosensitive bioink from chitosan hydrogels saturated with carbon dioxide and agarose. It focuses on a detailed characterisation of their physicochemical properties and potential applications in biomedicine and tissue engineering. The ORO test approved the rapid regeneration of the three-dimensional structure of chitosan–agarose composites in a unidirectional bench press...
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Managing Unemployment under COVID-19 Conditions (States of Emergency or Crisis)
PublikacjaRising unemployment is one of the consequences of the COVID-19 pandemic in many countries. This, in turn, has forcedpolicymakers to respond immediately with policy tools to minimize unemployment. The purpose of our study is to contribute toempirical knowledge by looking at activities of 40 local government units to counteract unemployment in the cross-border regionon the Polish side. In doing this, our study contributes to the...
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Osteoprotegerin gene polymorphism in diabetic Charcot neuroarthropathy
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Representing and describing nanomaterials in predictive nanoinformatics
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Impact of selected amino acids of HP0377 (Helicobacter pylori thiol oxidoreductase) on its functioning as a CcmG (cytochrome c maturation) protein and Dsb (disulfide bond) isomerase
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Molecularly targeted nanoparticles: an emerging tool for evaluation of expression of the receptor for advanced glycation end products in a murine model of peripheral artery disease
PublikacjaAbstract Background: Molecular imaging with molecularly targeted probes is a powerful tool for studying the spatio-temporal interactions between complex biological processes. The pivotal role of the receptor for advanced glycation end products (RAGE) in numerous pathological processes, aroused the demand for RAGE targeted imaging in various diseases. In the study, we evaluated the use of a diagnostic imaging agent for RAGE quantification...
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On the Conley index in Hilbert spaces - a multivalued case
PublikacjaW pracy podano definicję niezmiennika topologicznego wykrywającego zbiory niezmiennicze dla wielowartościowych układów dynamicznych generowanych przez inkluzje różniczkowe semiliniowe w przestrzeni Hilberta. Naszkicowano możliwość zastosowania do badania rozwiązań okresowych inkluzji hamiltonowskich.
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Degree of T-equivariant maps in R^n
PublikacjaW pracy przedstawiona jest konstrukcja niezmienniczego stopnia topologicznego dla odwzorowań z symetriami działających na przestrzeni euklidesowej z inwolucją. Udowodnione jest twierdzenie, że dwa dopuszczalne i gradientowe odwzorowania niezmiennicze są niezmienniczo homotopijne wtedy i tylko wtedy, gdy są one homotopijne niezmienniczo i gradientowo.
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Module structure in Conley theory with some applications
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On the Nielsen fixed point theory for multivalued mappings
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Connection matrix theory for discrete dynamical systems
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Connection matrix theory for discrete dynamical systems
PublikacjaIn [C] and [F1] the connection matrix theory for Morse decomposition is developedin the case of continuous dynamical systems. Our purpose is to study the case of discrete timedynamical systems.
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Approximative sequences and almost homoclinic solutions for a class of second order perturbed Hamiltonian systems
PublikacjaIn this work we will consider a class of second order perturbed Hamiltonian systems with a superquadratic growth condition on a time periodic potential and a small aperiodic forcing term. To get an almost homoclinic solution we approximate the original system by time periodic ones with larger and larger time periods. These approximative systems admit periodic solutions, and an almost homoclinic solution for the original system...
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Module structure in Conley theory with some applications
PublikacjaA multiplicative structure in the cohomological versjon of Conley index is described . In the case of equivariant flows we apply the normalization procedure known from equivariant degree theory and we propose a new continuation invariant. The theory is then applied to obtain a mountain pass type theorem. Another application is a result on multiple bifurcations for some elliptic PDE.
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A note on an approximative scheme of finding almost homoclinic solutions for Newtonian systems
PublikacjaIn this work we will be concerned with the existence of an almost homoclinic solution for a perturbed Newtonian system in a finite dimensional space. It is assumed that a potential is C^1 smooth and its gradient is bounded with respect to a time variable. Moreover, a forcing term is continuous, bounded and squere integrable. We will show that the appproximative scheme due to J. Janczewska for a time periodic potential extends to...
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3D Hierarchical Boron-Doped Diamond-Multilayered Graphene Nanowalls as an Efficient Supercapacitor Electrode
PublikacjaSynthesis of stable hybrid carbon nanostructure for high-performance supercapacitor electrode with long life-cycle for electronic and energy storage devices is a real challenge. Here, we present a one-step synthesis method to produce conductive boron-doped hybrid carbon nanowalls (HCNWs), where sp2-bonded graphene has been integrated with and over a three-dimensional curved wall-like network of sp3-bonded diamond. The spectroscopic...
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Genistein: a natural isoflavone with a potential for treatment of genetic diseases
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Why are behaviors of children suffering from various neuronopathic types of mucopolysaccharidoses different?
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Osteoblast and bacterial cell response on RGD peptide‐functionalized chitosan coatings electrophoretically deposited from different suspensions on Ti13Nb13Zr alloy
PublikacjaMetallic materials for long-term load-bearing implants still do not provide high antimicrobial activity while maintaining strong compatibility with bone cells. This study aimed to modify the surface of Ti13Nb13Zr alloy by electrophoretic deposition of a chitosan coating with a covalently attached Arg-Gly-Asp (RGD) peptide. The suspensions for coating deposition were prepared in two different ways either using hydroxyacetic acid...
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8-Oxo-7,8-dihydroguanine and uric acid as efficient predictors of survival in colon cancer patients
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Lactoferrin B Combined with Antibiotics Exhibits Leukemic Selectivity and Antimicrobial Activity
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Lactoferricin B Combined with Antibiotics Exhibits Leukemic Selectivity and Antimicrobial Activity
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Lactoferricin B Combined with Antibiotics Exhibits Leukemic Selectivity and Antimicrobial Activity
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Assessment of Clinical Usefulness of Resting Electrocardiogram (PH-ECG Score) in Monitoring the Efficacy of Balloon Pulmonary Angioplasty (BPA) in Patients with Chronic Thromboembolic Pulmonary Hypertension (CTEPH)
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The process of fuzzy model development for the case of polish internet mortgage market
PublikacjaThe aim of the paper is to present the conceptual description of fuzzy model representing the Polish Internet mortgage market. The first part of the paper consists of assessment and verification of model variables which are important for the Polish Internet Mortgage Market. This process begins with the initial set of variables which was used previously for the rule based model of the same market. As numerous aspects of the market...
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[18F]Amylovis as a Potential PET Probe for β-Amyloid Plaque: Synthesis, In Silico, In vitro and In vivo Evaluations
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P.238 Lithium treatment modulates the expression of inflammation involved genes in major depressive disorder
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Analysis of the Link between the Redox State and Enzymatic Activity of the HtrA (DegP) Protein from Escherichia coli
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HLA-DQA1*05 Associates with Extensive Ulcerative Colitis at Diagnosis: An Observational Study in Children
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Safety and Outcomes of Inferior Vena Cava Filter Placement in Oncology Patients: A Single-Centre Experience
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Oxidative stress and 8-oxoguanine repair are enhanced in colon adenoma and carcinoma patients
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MCORD: MPD cosmic ray detector for NICA
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In vivo evidence of ascorbate involvement in the generation of epigenetic DNA modifications in leukocytes from patients with colorectal carcinoma, benign adenoma and inflammatory bowel disease
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Synthesis, Chemical Characterization and Multiscale Biological Evaluation of a dimericcRGD Peptide for Targeted Imaging of αVβ3 Integrin Activity
PublikacjaCyclic peptides containing the Arg-Gly-Asp (RGD) sequence have been shown to specifically bind the angiogenesis biomarker α V β3 integrin. We report the synthesis, chemical characterization, and biological evaluation of two novel dimeric cyclic RGD-based molecular probes for the targeted imaging of α V β3 activity (a radiolabeled version, 64Cu-NOTA-PEG4-cRGD2, for PET imaging, and a fluorescent version, FITC-PEG4-cRGD2, for in...
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Characteristic profiles of DNA epigenetic modifications in colon cancer and its predisposing conditions—benign adenomas and inflammatory bowel disease
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Emerging Role of Balloon Pulmonary Angioplasty in Chronic Thromboembolic Pulmonary Disease—Insights from the 2022 ESC Guidelines
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B13 Can Dna Methylation Be A Factor In The Pathogenesis Of Huntington's Disease?
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Ibrutinib versus temsirolimus in patients with relapsed or refractory mantle-cell lymphoma: an international, randomised, open-label, phase 3 study
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A computational view on nanomaterial intrinsic and extrinsic features for nanosafety and sustainability
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MCORD - MPD Cosmic Ray Detector a new features
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Transcriptome Changes in Three Brain Regions during Chronic Lithium Administration in the Rat Models of Mania and Depression
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Genes involved in glucocorticoid receptor signalling affect susceptibility to mood disorders
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Characteristics and Outcomes of Patients Consulted by a Multidisciplinary Pulmonary Embolism Response Team: 5-Year Experience
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Outcome-Driven Thresholds for Ambulatory Blood Pressure Based on the New American College of Cardiology/American Heart Association Classification of Hypertension
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Do we know more about hypertension in Poland after the May Measurement Month 2017?—Europe
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Ryzyko na rynku kredytów hipotecznych
PublikacjaW referacie przedstawiono podział ryzyka bankowego oraz precyzyjnie zdefiniowano pojęcie kredytu hipotecznego. Analizie poddano rozmiary rynku kredytów hipotecznych dla osób prywatnych w Polsce, ze szczególnym naciskiem na kredyty mieszkaniowe, które stanowią najważniejszy segment omawianego rynku. Zbadano także wartość kredytów zagrożonych. Ocenie poddano wpływ wybranych czynników, na zmiany w obszarze ryzyka bankowego, związane...
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Polityka podatkowa przedsiębiorców po zmianach prawa podatkowego
PublikacjaPo zmianach prawa finansowego wprowadzonych w Polsce po 01 stycznia 2001 r. prawo podatkowe stwarza dobre warunki do uprawiania polityki podatkowej przez przedsiębiorców.
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Wpływ ryzyka finansowego na aktywa gospodarstw domowych w Polsce
PublikacjaNiezależnie od uzyskiwanych dochodów każde gospodarstwo domowe jest uczestnikiem rynku finansowego. Z każdym wykorzystywanym przez niego instrumentem finansowym wiąże się określone ryzyko finansowe. Ryzyko to może wpłynąć na wzrost bądź spadek aktywów finansowych tych podmiotów, niezależnie od podejmowanych przez niego działań. Celem niniejszego opracowania jest określenie podstawowych rodzajów ryzyka związanego z obecnością gospodarstw...