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Wyniki wyszukiwania dla: SAR
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A nanostructured carbon-reinforced polyisobutylene-based thermoplastic elastomer
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Uptake and Release of Double‐Walled Carbon Nanotubes by Mammalian Cells
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Interventions reducing car usage: Systematic review and meta-analysis
PublikacjaThis systematic literature review aimed to investigate the extent to which transport-related interventions induced a reduction in car use. Both qualitative synthesis and meta-analysis were employed. The synthesis included 31 original studies, while the meta-analysis included 21. Of the qualitatively synthesised studies, 74 % demonstrated that interventions were effective in reducing car use. The pooled estimates of the effects...
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Which transport policies increase physical activity of the whole of society? A systematic review
PublikacjaPurpose: There is strong evidence of the links between car-dependence and the physical inactivity pandemic. Physical inactivity accounts for 6–10% of major non-communicable diseases. Research consistently shows that unlike passive transport, active transport is associated with higher total daily physical activity (PA). While there are public policies that support PA in transport and, as a result, overall PA levels, the specific...
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Electrochromic foil-based devices: optical transmittance and modulation range, effect of ultraviolet irradiation,and quality assessment by 1/f current noise
PublikacjaPrzedstawiono technologię wytwarzania elementów wykazujących zjawisko elektrochromizmu - zmiany transmitancji optycznej pod wpływem gromadzenia ładunku. Pokazano, że zastosowanie warstwy odbijającej może poprawić stopień zmian transmitancji optycznej. Ponadto, pokazano, że zjawiska losowe generujące szum typu 1/f w tych elementach może być wykorzystane do oceny ich jakości.
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O07 Filaggrin insufficiency renders keratinocyte-derived small extracellular vesicles capable of affecting CD1a-mediated T-cell responses and promoting allergic inflammation
PublikacjaThe association between FLG loss-of-function mutations and the development of atopic dermatitis (AD) indicates that filaggrin is critical to skin barrier function; the mutations are also linked to additional allergic manifestations, but it is unknown how the skin may influence inflammation in distant tissues. Here we investigated the impact of filaggrin insufficiency on keratinocyte-derived exosome-enriched small extracellular...
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Keratinocyte-derived small extracellular vesicles supply antigens for CD1a-resticted T cells and promote their type 2 bias in the context of filaggrin insufficiency
PublikacjaIntroduction: Exosome-enriched small extracellular vesicles (sEVs) are nanosized organelles known to participate in long distance communication between cells, including in the skin. Atopic dermatitis (AD) is a chronic inflammatory skin disease for which filaggrin (FLG) gene mutations are the strongest genetic risk factor. Filaggrin insufficiency affects multiple cellular function, but it is unclear if sEV-mediated cellular communication...
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Surface-enhanced Raman scattering (SERS) and tip-enhanced Raman scattering (TERS) in label-free characterization of erythrocyte membranes and extracellular vesicles at the nano-scale and molecular level
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Venetoclax in relapsed or refractory chronic lymphocytic leukaemia with 17p deletion: a multicentre, open-label, phase 2 study
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Phytotherapy and food applications from Brassica genus
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SPARC, a Novel Regulator of Vascular Cell Function in Pulmonary Hypertension
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Cathepsin G activity lowers plasma LDL and reduces atherosclerosis
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Induced Pluripotent Stem Cell (iPSC)–Derived Extracellular Vesicles Are Safer and More Effective for Cardiac Repair Than iPSCs
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Converting beach wrack into a resource as a challenge for the Baltic Sea (an overview)
PublikacjaThe paper distinguishes beach wrack, the marine generated organic part of beach cast, as a separate management object and discusses research questions related to its management and economically viable use. Based on experiences from the Baltic Sea and existing practices from countries with different management systems clear distinction between the management of natural and anthropogenic components of cast material is seen as an...
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Static in vitro digestion model adapted to the general older adult population: an INFOGEST international consensus
PublikacjaUnderstanding the mechanisms of food digestion is of paramount importance to determine the effect foods have on human health. Significant knowledge on the fate of food during digestion has been generated in healthy adults due to the development of physiologically-relevant in vitro digestion models. However, it appears that the performance of the oro-gastrointestinal tract is affected by ageing and that a model simulating the digestive...
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Therapeutic targeting of cathepsin C: from pathophysiology to treatment
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Natural Resources for Human Health: A New Interdisciplinary Journal Dedicated to Natural Sciences
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Evaluation of the BNT162b2 Covid-19 Vaccine in Children 5 to 11 Years of Age
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ERCC1-deficient cells and mice are hypersensitive to lipid peroxidation
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Sequence-dependent structural properties of B-DNA: what have we learned in 40 years?
PublikacjaThe structure of B-DNA, the physiological form of the DNA molecule, has been a central topic in biology, chemistry and physics. Far from uniform and rigid, the double helix was revealed as a flexible and structurally polymorphic molecule. Conformational changes that lead to local and global changes in the helix geometry are mediated by a complex choreography of base and backbone rearrangements affecting the ability of the B-DNA...
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Documenting the de-identification process of clinical and imaging data for AI for health imaging projects
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Country‐level and individual‐level predictors of men's support for gender equality in 42 countries
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13th International Conference on Conservative Management of Spinal Deformities and First Joint Meeting of the International Research Society on Spinal Deformities and the Society on Scoliosis Orthopaedic and Rehabilitation Treatment – SOSORT-IRSSD 2016 meeting
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Gendered Self-Views Across 62 Countries: A Test of Competing Models
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Psychometric Properties and Correlates of Precarious Manhood Beliefs in 62 Nations
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Pediatric trauma and emergency surgery: an international cross-sectional survey among WSES members
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An analysis and evaluation of the WeFold collaborative for protein structure prediction and its pipelines in CASP11 and CASP12
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18th European Symposium on Radiopharmacy and Radiopharmaceuticals
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Belief in a zero-sum game and subjective well-being across 35 countries
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INFOGEST inter-laboratory recommendations for assaying gastric and pancreatic lipases activities prior to in vitro digestion studies
PublikacjaIn vitro digestion studies often use animal digestive enzyme extracts as substitutes of human gastric and pancreatic secretions. Pancreatin from porcine origin is thus commonly used to provide relevant pancreatic enzymes such as proteases, amylase and lipase. Rabbit gastric extracts (RGE) have been recently introduced to provide gastric lipase in addition to pepsin. Before preparing simulated gastric and pancreatic extracts with...
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Sparse autoregressive modeling
PublikacjaIn the paper the comparison of the popular pitch determination (PD) algorithms for thepurpose of elimination of clicks from archive audio signals using sparse autoregressive (SAR)modeling is presented. The SAR signal representation has been widely used in code-excitedlinear prediction (CELP) systems. The appropriate construction of the SAR model is requiredto guarantee model stability. For this reason the signal representation...
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Are the short cationic lipopeptides bacterial membrane disruptors? Structure-Activity Relationship and molecular dynamic evaluation
PublikacjaShort cationic lipopeptides are amphiphilic molecules that exhibit antimicrobial activity mainly against Grampositives. These compounds bind to bacterial membranes and disrupt their integrity. Here we examine the structure-activity relation (SAR) of lysine-based lipopeptides, with a prospect to rationally design more active compounds. The presented study aims to explain how antimicrobial activity of lipopeptides is affected by...
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The Unrestricted Global effort to complete the Closed Or Open after Source Control Laparotomy for Severe Complicated Intra-Abdominal Sepsis (COOL) Trial
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The unrestricted global effort to complete the COOL trial
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Surgical site infection after gastrointestinal surgery in high-income, middle-income, and low-income countries: a prospective, international, multicentre cohort study
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Prediction of protein assemblies, the next frontier: The CASP14‐CAPRI experiment
PublikacjaWe present the results for CAPRI Round 50, the 4th joint CASP-CAPRI protein assembly prediction challenge. The Round comprised a total of 12 targets, including 6 dimers, 3 trimers, and 3 higher-order oligomers. Four of these were easy targets, for which good structural templates were available either for the full assembly, or for the main interfaces (of the higher-order oligomers). Eight were difficult targets for which only distantly...
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Global variation in anastomosis and end colostomy formation following left‐sided colorectal resection
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Pooled analysis of WHO Surgical Safety Checklist use and mortality after emergency laparotomy
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A global multinational survey of cefotaxime-resistant coliforms in urban wastewater treatment plants
PublikacjaThe World Health Organization Global Action Plan recommends integrated surveillance programs as crucial strategies for monitoring antibiotic resistance. Although several national surveillance programs are in place for clinical and veterinary settings, no such schemes exist for monitoring antibiotic-resistant bacteria in the environment. In this transnational study, we developed, validated, and tested a low-cost surveillance and...
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Comparability of Raman Spectroscopic Configurations: A Large Scale Cross-Laboratory Study
PublikacjaThe variable configuration of Raman spectroscopic platforms is one of the major obstacles in establishing Raman spectroscopy as a valuable physicochemical method within real-world scenarios such as clinical diagnostics. For such real world applications like diagnostic classification, the models should ideally be usable to predict data from different setups. Whether it is done by training a rugged model with data from many setups...
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The ChoCO-W prospective observational global study: Does COVID-19 increase gangrenous cholecystitis?
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Incidence of severe critical events in paediatric anaesthesia (APRICOT): a prospective multicentre observational study in 261 hospitals in Europe
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Effects of hospital facilities on patient outcomes after cancer surgery: an international, prospective, observational study
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Global variation in postoperative mortality and complications after cancer surgery: a multicentre, prospective cohort study in 82 countries
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Coastline change-detection method using remote sensing satellite observation data
PublikacjaCoastal zones are not only the fundaments for local economics based on trade, shipping and transport services, but also a source of food, energy and resources. Apart from offering diverse opportunities for recreation and tourism, coastal zones provide protection against storms and other meteorological disturbances. Environmental information is also essential because of the direct influence on a country’s maritime zones, which are...
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10Kin1day: A Bottom-Up Neuroimaging Initiative
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10Kin1day: A bottom-up neuroimaging initiative
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Appropriate Shocks and Mortality in Patients With Versus Without Diabetes With Prophylactic Implantable Cardioverter Defibrillators
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Prospective Observational Study on acute Appendicitis Worldwide (POSAW)
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Diversity and ethics in trauma and acute care surgery teams: results from an international survey
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