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Wyniki wyszukiwania dla: PRINCIPLES OF GREEN ANALYTICAL CHEMISTRY
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State of the art and prospects of methods for determination of lipophilicity of chemical compounds
PublikacjaLipophilicity of the compounds is useful to (i) explain their distribution in biological systems, which is different in plant and in animal organisms, (ii) predict the possible pathways of pollutant transport in the environment, and (iii) support drug discovery process and select optimal composition in terms of bioactivity and bioavailability. The lipophilic properties can be determined by two main approaches, experimental, which...
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Recent trends in determination of neurotoxins in aquatic environmental samples
PublikacjaAnatoxins, saxitoxins, ciguatoxins, beta-N-methylamino-l-alanine and its isomers are groups of neurotoxins which have a highly specific effect on the nervous system of animals, including humans, by interfering with the transmission of nerve impulses. In order to assess the human exposure to these neurotoxins, selective, interlaboratory-validated analytical methods are being developed to facilitate obtaining reliable results on...
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State of the art in sample preparation for human breast milk metabolomics—merits and limitations
PublikacjaHuman breast milk (HBM) contains metabolites that are diverse in chemical structure and concentration. These metabolites range from high-abundance to low-abundance compounds and from polar to nonpolar. This complex nature of HBM makes HBM samples difficult to analyze, especially in global metabolomic studies for the determination and characterization of complete sets of metabolites. In this review, the state of the art in sample...
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Solid Phase Microextraction: Apparatus, Sorbent Materials, and Application.
Publikacjahe primary objective of this review article is to strategically screen and highlight the advancements in the area of solid phase microextraction (SPME). The plenty of review articles have been written on different aspects of SPME, this review is dedicated to provide the brief but clear overview of the research footprints so produced from SPME. Some of the key advancements in types and designs, coating materials, coating strategies,...
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Birds' feathers – Suitable samples for determination of environmental pollutants
PublikacjaThe intensive development of industry and human population results in large amounts of different xenobiotic emitted into individual ecosystem components. As a consequence, monitoring of the level of pollution of particular elements of the environment by exotoxins has become a common interest. The determination of environmental changes by different types of biological indicators is called bioindication, which is used as one of the...
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The Current State-of-the-Art in the Determination of Pharmaceutical Residues in Environmental Matrices Using Hyphenated Techniques
PublikacjaSeveral thousand tons of pharmaceuticals and their transformation products (metabolites and degradation products) are introduced into the environment each year. They affect both human health and the environment, therefore, analytical procedures enabling the determination of a wide range of pharmaceuticals at trace levelswithminimal effort, time, and energy are required. Nowadays, hyphenated techniques are commonly applied in pharmaceutical...
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Occurrence of Surface Active Agents in the Environment
PublikacjaDue to the specific structure of surfactants molecules they are applied in different areas of human activity (industry, household). After using and discharging from wastewater treatment plants as effluent stream, surface active agents (SAAs) are emitted to various elements of the environment (atmosphere, waters, and solid phases), where they can undergo numerous physic-chemical processes (e.g., sorption, degradation) and freely...
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Application of gas chromatography to the analysis of spirit-based alcoholic beverages
PublikacjaSpirit-based beverages are alcoholic drinks, which production processes are dependent on the type and origin of raw materials. The composition of this complex matrix is difficult to analyze and scientists commonly choose a gas chromatography techniques for this reason. With a wide selection of extraction methods and detectors it is possible to provide qualitative and quantitative analysis for many chemical compounds with a various...
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Devices for the production of reference gas mixtures
PublikacjaFor many years there has been growing demand for gaseous reference materials, which is connected with development in many fields of science and technology. As a result, new methodological and instrumental solutions appear that can be used for this purpose. Appropriate quality assurance/quality control (QA/QC) must be used to make sure that measurement data are a reliable source of information. Reference materials are a significant...
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Application of modern sample-preparation techniques to the determination of chloropropanols in food samples
PublikacjaChloropropanols are heat-induced food toxicants that recently caused concern among industrial and scientific experts. World and European organizations related to food safety asked researchers to investigate mitigation strategies regarding these contaminants. The essential objective of this project was development of fast analytical methods enabling reliable determination and quantification of 3-monochloropropane-1,2-diol, 2-monochloropropane-1,3-diol...
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Standard gas mixtures- indispensable reference materials in the analysis of gaseous media
PublikacjaIn recent years the need for the quality control and assurance of analytical measurement results has been particularly strongly emphasised. Certified reference materials play an invaluable role in this process. The article characterises the basic types of reference materials, focusing in particular on those in the gaseous state. It also reviews the literature on the techniques of preparing standard gas mixtures over the last ten...
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Sample preparation and recent trends in volatolomics for diagnosing gastrointestinal diseases
PublikacjaThe analysis of the human volatilome can be successfully used for rapid and non-invasive diagnostics of gastrointestinal diseases. However, the introduction of techniques based on detection of volatiles is limited, among other factors, by difficulties which arise during the sampling stage and instrumental analysis. The aim of this article was to review and discuss medical and analytical literature on the analysis of volatiles in...
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Literature update of analytical methods for biogenic amines determination in food and beverages
PublikacjaBiogenic amines (BAs) have been reported in a variety of foods, such as fish, meat, cheese, and wines. The formation of BAs in food by the microbial decarboxylation of amino acids can result in human allergic reactions, characterized by difficulty in breathing, rash, vomiting, and hypertension. Control measures to prevent biogenic amine formation in foods and/or reduce their levels should be considered. Therefore, monitoring of...
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Two-Dimensional Gas Chromatography Coupled With Mass Spectrometry in Food Analysis
PublikacjaThe development of instrumental analytical techniques provided the opportunity for in-depth characterization of many food matrices. In particular, the use of gas chromatography coupled with mass spectrometry gives impressive results in terms of quality and authenticity testing, conducting food freshness evaluations and contamination assessments. A new variant of gas chromatography, namely two-dimensional gas chromatography (GC...
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Analysis of MArkers of Exposure to Constituents of Environmental Tobacco Smoke (ETS)
PublikacjaTobacco smoke is a complex mixture of more than 4000 chemical compounds, many of which are harmful to human health. These compounds belong to various chemical classes, including amides, imides, lactams, carboxylic acids, aldehydes, ketones, alcohols, phenols, amines, hydrocarbons, ethers, and inorganic compounds. There are three types of tobacco smoke streams: the mainstream, the sidestream, and environmental tobacco smoke (ETS)....
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Comparison of different techniques for extracting Polychlorinated Biphenyls from bottom sediment samples using Isotope Dilution Mass Spectrometry
PublikacjaIn this work, problems that may occur during determination of trace levels of polychlorinated biphenyls in sediment samples are described. The main error sources are connected with extraction of analytes prior to final determination. During model studies, polychlorinated biphenyls have been extracted from sediment reference material (METRANAL 2) with the use of different solvents (dichloromethane, hexane, and toluene); the process...
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Testing and sampling devices for monitoring volatile and semi-volatile organic compounds in indoor air
PublikacjaAdults spend most of their time in enclosed spaces (e.g., apartment, office and public buildings). According to research conducted by scientists, air quality indoors is much worse than the ambient air quality outdoors. Hazardous chemicals found in air indoors can adversely affect the functioning of the human body and cause many respiratory and circulatory diseases. Harmful chemical compounds (mainly volatile organic compounds and...
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Analysis of arsenic species in environmental samples
PublikacjaMany analytical methods for determining arsenic in various forms in environmental samples have been developed in recent years. The main objective of this review article is the presentation and comparison of the three principal techniques for the determination arsenic compounds, namely: hydride generation (HG), voltammetry and chromatography (liquid chromatography including high-performance liquid chromatography (HPLC), and gas...
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The Role of and the Place of Method Validation in the Quality Assurance and Quality Control (QA/QC) System
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Quality problems in determination of organic compounds in environmental samples, such as PAHs and PCBs
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Standard gas mixtures – indispensable reference materials in the analysis of gaseous media
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Gaseous standard mixtures – the challenge of obtaining small amounts of measurands
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Prospects for the Production, Research and Utilization of Reference Materials
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Validation of a sampling procedure
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Gradient reversed-phase high-performance chromatography of ionogenic analytes
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Critical approach to PLE technique application in the analysis of secondary metabolites in plants
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Recent achievements in element analysis of bee honeys by atomic and mass spectrometry methods
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Advances in assessing the elemental composition of distilled spirits using atomic spectrometry
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Chemical-vapor generation of transition metals through the reaction with tetrahydroborate in recent achievements in analytical atomic spectrometry
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Critical evaluation of recent achievements in low power glow discharge generated at atmospheric pressure between a flowing liquid cathode and a metallic anode for element analysis by optical emission spectrometry
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Development of direct-current, atmospheric-pressure, glow discharges generated in contact with flowing electrolyte solutions for elemental analysis by optical emission spectrometry
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Impact and practicability of recently introduced requirements on elemental impurities
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Cold atmospheric plasma-induced chemical vapor generation in trace element analysis by spectrometric methods
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Determination of aminoglycoside antibiotics: Current status and future trends
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Element analysis of bee-collected pollen and bee bread by atomic and mass spectrometry – Methodological development in addition to environmental and nutritional aspects
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Perspectives and challenges in extracellular vesicles untargeted metabolomics analysis
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Recent breakthroughs in the stability testing of pharmaceutical compounds
PublikacjaPharmaceutical development is mostly focused on the research leading to approval of a new and viable active substance. However, there is a number of old generation compounds that are still being used in contemporary medicinal practice. So that new analytical developments should cover not only the safety of newly developed drug substances, which is obvious, but should also be directed into the search of individual stability issues...
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A Comprehensive Review on Shilajit: What We Know about Its Chemical Composition
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Trends in biomedical analysis of red blood cells – Raman spectroscopy against other spectroscopic, microscopic and classical techniques
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Complementarity of electronic and vibrational circular dichroism based on stereochemical studies of vic-diols
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Limitations of Integrative Passive Samplers as a Tool for the Quantification of Pharmaceuticals in the Environment – A Critical Review with the Latest Innovations
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Calibration of Passive Samplers for the Monitoring of Pharmaceuticals in Water-Sampling Rate Variation
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Analytical studies on the environmental state of the Svalbard Archipelago provide a critical source of information about anthropogenic global impact
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Modern solutions in the field of microextraction using liquid as a medium of extraction
PublikacjaThe monitoring of compounds present in samples at trace/ultra-trace level usually requires a preliminary step of isolation and/or enrichment of analytes. Against, sample preparation is considered as crucial part of whole analytical procedures, in particular in samples characterized by complex matrices composition. Several new miniaturized extraction techniques is introduced and extensively applied to different type of samples....
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Application of electrochemical sensors and sensor matrixes for measurement of odorous chemical compounds
PublikacjaIn this paper describes the principle of operation of the electrochemical sensors and the sensor matrixes comprised of electrochemical sensors intended for measurement of odorous compounds. Critical comparison of these sensors’ advantages and disadvantages has been made. The fields of economy contributing to release of odours and the potential sources of their emission have been identified. Commercially available electrochemical...
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Application of Ionic Liquids in Amperometric Gas Sensors
PublikacjaThis article presents an analysis of available literature data on metrological parameters of the amperometric gas sensors containing ionic liquids as an electrolyte. Four mechanism types of signal generation in amperometric sensors with ionic liquid are described. Moreover, this article describes the influence of selected physico-chemical properties of the ionic liquids on the metrological parameters of these sensors. Some metrological...
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Modern trends in solid phase extraction: New sorbent media
PublikacjaBased on the recently published literature, this review provides an update of the most important features and application of formats and devices employed in solid phase extraction (SPE). Special attention was paid on new trapping media proposed in SPE prior the chromatography analysis, based on the use of nanostructured materials, including carbon nanomaterials, electrospun nanofibers, dendrimes and magnetic nanoparticles, molecular...
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Novel Desorber for Online Drilling Mud Gas Logging
PublikacjaThis work presents the construction solution and experimental results of a novel desorber for online drilling mud gas logging. The traditional desorbers use mechanical mixing of the liquid to stimulate transfer of hydrocarbons to the gaseous phase that is further analyzed. The presented approach is based on transfer of hydrocarbons from the liquid to the gas bubbles flowing through it and further gas analysis. The desorber was...
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Analytical procedures for quality control of pharmaceuticals in terms of residual solvents content: Challenges and recent developments
PublikacjaResidual solvents play an important role in the synthesis of drugs and in product formulations. In addition, they pose a serious problem, that is toxicity, as many of them exhibit toxic or environmentally hazardous properties. Therefore, constant monitoring of quality control is needed. In this study, we present an overview of regulatory and general methods described by various pharmacopoeias. Then, the most commonly used methodologies...
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Dopants and gas modifiers in ion mobility spectrometry
PublikacjaThe ion mobility techniques, including the most commonly used drift-tube ion mobility spectrometry (IMS) and differential mobility spectrometry (DMS), are used successfully for the detection of a wide range of organic compounds in the gas phase. In order to improve detection quality, admixtures are added to gas streams flowing through the detector. Dopants mostly prevent the ionization of interfering chemicals however, better detection...